ES2007341A6 - Un procedimiento para producir m-csf - Google Patents

Un procedimiento para producir m-csf

Info

Publication number
ES2007341A6
ES2007341A6 ES878701345A ES8701345A ES2007341A6 ES 2007341 A6 ES2007341 A6 ES 2007341A6 ES 878701345 A ES878701345 A ES 878701345A ES 8701345 A ES8701345 A ES 8701345A ES 2007341 A6 ES2007341 A6 ES 2007341A6
Authority
ES
Spain
Prior art keywords
csf
procedure
producing
sequence
macrophagus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES878701345A
Other languages
English (en)
Inventor
Steven C Clark
Gordon G Wong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetics Institute LLC
Original Assignee
Genetics Institute LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/860,377 external-priority patent/US4879227A/en
Priority claimed from US06/940,362 external-priority patent/US4868119A/en
Application filed by Genetics Institute LLC filed Critical Genetics Institute LLC
Publication of ES2007341A6 publication Critical patent/ES2007341A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Prostheses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

UN PROCEDIMIENTO PARA PRODUCIR M-CSF (FACTOR ESTIMULANTE DE COLONIAS DE MACROFAGOS).COMPRENDE: CULTIVAR UNA CELULA ADECUADA TRANSFORMADA CON UNA SECUENCIA DE CDNA QUE CODIFICA UNA PROTEINA QUE CONTIENE LA SIGUIENTE SECUENCIA DE AMINOACIDOS:ESTANDO DICHA SECUENCIA EN ASOCIACION OPERATIVA CON UNA SECUENCIA DE CONTROL DE EXPRESION PARA ESTA.TIENE UTILIDAD PARA EL TRATAMIENTO TERAPEUTICO DE LOS TRASTORNOS CARACTERIZADOS POR DEFICIENCIAS EN LAS CELULAS HEMATOPOYETICAS.
ES878701345A 1986-05-06 1987-05-05 Un procedimiento para producir m-csf Expired ES2007341A6 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/860,377 US4879227A (en) 1986-05-06 1986-05-06 Production of a recombinant human colony stimulating factor
US06/940,362 US4868119A (en) 1986-12-11 1986-12-11 Hematopoietic growth factors

Publications (1)

Publication Number Publication Date
ES2007341A6 true ES2007341A6 (es) 1989-06-16

Family

ID=27127565

Family Applications (1)

Application Number Title Priority Date Filing Date
ES878701345A Expired ES2007341A6 (es) 1986-05-06 1987-05-05 Un procedimiento para producir m-csf

Country Status (21)

Country Link
US (1) US5573763A (es)
EP (1) EP0307402B1 (es)
JP (2) JP2579981B2 (es)
KR (1) KR960004453B1 (es)
AT (1) ATE92966T1 (es)
AU (1) AU606056B2 (es)
CA (1) CA1334942C (es)
DE (1) DE3787020T2 (es)
DK (1) DK2688A (es)
ES (1) ES2007341A6 (es)
FI (1) FI884877L (es)
GR (1) GR870688B (es)
HU (1) HU212277B (es)
IE (1) IE60835B1 (es)
IL (1) IL82400A0 (es)
MX (1) MX9203130A (es)
MY (1) MY101209A (es)
NO (1) NO880022D0 (es)
OA (1) OA09112A (es)
PH (1) PH24301A (es)
WO (1) WO1987006954A1 (es)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5422105A (en) * 1985-02-05 1995-06-06 Cetus Oncology Corporation Use of recombinant colony stimulating factor 1
US5556620A (en) * 1985-02-05 1996-09-17 Cetus Oncology Corporation Use of recombinant colony stimulating factor-1 to enhance wound healing
AU594045B2 (en) * 1985-02-05 1990-03-01 Chiron Corporation Recombinant colony stimulating factor-1
US5837229A (en) * 1985-02-05 1998-11-17 Chiron Corporation Uses of recombinant colony stimulating factor-1
US4847201A (en) * 1985-02-05 1989-07-11 Cetus Corporation DNA encoding for CSF-1 and accompanying recombinant systems
US5573930A (en) * 1985-02-05 1996-11-12 Cetus Oncology Corporation DNA encoding various forms of colony stimulating factor-1
US6156300A (en) * 1985-02-05 2000-12-05 Chiron Corporation Point mutants of N∇2 CSF-1 and carboxy truncated fragments thereof
US5104650A (en) * 1985-02-05 1992-04-14 Cetus Corporation Uses of recombinant colony stimulating factor-1
US6117422A (en) * 1985-02-05 2000-09-12 Chiron Corporation N∇2-CSF-1(long form) and carboxy truncated fragments thereof
US4808611A (en) * 1986-07-30 1989-02-28 Immunex Corporation Use of interleukin-1 to induce development of multipotent hemopoietic cell populations
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子
JP2583829B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 ヒトｍ−ｃｓｆ
US5650297A (en) * 1986-09-17 1997-07-22 Otsuka Pharmaceutical Co., Ltd. DNA encoding human colony-stimulating factors
JPH07100720B2 (ja) * 1987-07-17 1995-11-01 森永乳業株式会社 コロニー刺激因子の製造法
IL86090A (en) * 1987-04-16 1993-03-15 Cetus Oncology Corp Production of purified, biologically active, bacterially produced recombinant human csf-1
CA1339757C (en) * 1987-04-16 1998-03-17 Robert F. Halenbeck Production of purified biologically active, bacterially produced recombinant human csf-1
US4929700A (en) * 1987-04-16 1990-05-29 Cetus Corporation Production of purified, biologically active, bacterially produced recombinant human CSF-1
DE3853721T2 (de) * 1987-09-22 1995-10-19 Cetus Oncology Corp Verwendungen von rekombinantem koloniestimulierendem faktor-1.
US5260421A (en) * 1987-12-21 1993-11-09 Applied Research Systems Ars Holding N.V. Site-directed mutagenesis modified glycoprotein hormones
US4847325A (en) * 1988-01-20 1989-07-11 Cetus Corporation Conjugation of polymer to colony stimulating factor-1
DK54589A (da) * 1988-02-08 1989-08-09 Otsuka Pharma Co Ltd Humane kolonistmulerende faktorer
JPH0610137B2 (ja) * 1988-02-29 1994-02-09 新技術事業団 ヒト単球−マクロファージコロニー刺激因子を有効成分とする造血器疾患治療剤
WO1989010158A1 (en) * 1988-04-27 1989-11-02 Immunomedics, Inc. Improved radiotherapy
US5888495A (en) * 1988-05-23 1999-03-30 Genetics Institute, Inc. Method of producing storage stable M-CSF lyophilizates
US5171675A (en) * 1988-07-28 1992-12-15 Cerretti Douglas P Macrophage colony stimulating factor-γ
US5178855A (en) * 1989-01-30 1993-01-12 Schering Corporation Treatment of luekocyte dysfunction with GM-CSF
ES2091816T3 (es) * 1989-02-10 1996-11-16 Cetus Oncology Corp Anticuerpos monoclonales del factor estimulador de colonias de macrofagos (m-csf) que reconocen un epitope conformacional neutralizante.
US5288487A (en) * 1989-02-28 1994-02-22 Morinaga Milk Industry Co., Ltd. Human monocyte-macrophage-CSF preparations
AU625081B2 (en) * 1989-02-28 1992-07-02 Morinaga Milk Industry Company Limited Human monocyte-macrophage-csf preparations
AU5355790A (en) * 1989-04-19 1990-11-16 Cetus Corporation Multifunctional m-csf proteins and genes encoding therefor
DE69026440T2 (de) * 1989-07-27 1996-10-17 Denki Kagaku Kogyo Kk Für M-CSF kodierendes Gen und dazu gehörende rekombinante Systeme
JPH08505534A (ja) * 1993-01-13 1996-06-18 森永乳業株式会社 Ｍ−ｃｓｆ２２３の製造方法
ATE386811T1 (de) 1996-04-05 2008-03-15 Novartis Vaccines & Diagnostic Alphaviren-vektors mit eine reduzierte inhibierung der synthese von zellmakromolekülen
US6455678B1 (en) * 1996-04-26 2002-09-24 Amcell Corporation Human hematopoietic stem and progenitor cell antigen
EP0937461B1 (en) * 1996-07-10 2005-07-06 Meiji Dairies Corporation Use of proteins from the mk family as hematopoietic factor
AU6283299A (en) * 1998-10-01 2000-04-17 Elan Pharma International Limited Controlled release nanoparticulate compositions
US7108852B2 (en) 2000-03-20 2006-09-19 Warner-Lambert Company Llc Methods of treating inflammation using antibodies to M-CSF
AR045563A1 (es) 2003-09-10 2005-11-02 Warner Lambert Co Anticuerpos dirigidos a m-csf
WO2008060610A2 (en) * 2006-11-17 2008-05-22 Biogen Idec Ma Inc. Systemic administration of colony stimulating factors to treat amyloid associated disorders
EP4309666A1 (en) 2022-07-21 2024-01-24 Technische Universität Dresden M-csf for use in the prophylaxis and/or treatment of viral infections in states of immunosuppression
US20260041734A1 (en) 2022-07-21 2026-02-12 Technische Universität Dresden M-csf for use in the prophylaxis and/or treatment of viral infections in states of immunosuppression

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4784949A (en) * 1984-04-19 1988-11-15 Cetus Corporation Universal dominant selectable marker cassette
DE3686794T2 (de) * 1985-02-05 1993-03-04 Cetus Oncology Corp Reinigung des natuerlichen kolonie-stimulierenden faktors-1.
US4847201A (en) * 1985-02-05 1989-07-11 Cetus Corporation DNA encoding for CSF-1 and accompanying recombinant systems
AU594045B2 (en) * 1985-02-05 1990-03-01 Chiron Corporation Recombinant colony stimulating factor-1
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子
WO1988003173A2 (en) * 1986-10-24 1988-05-05 Cetus Corporation New forms of colony stimulating factor-1

Also Published As

Publication number Publication date
JP2579981B2 (ja) 1997-02-12
PH24301A (en) 1990-05-29
AU606056B2 (en) 1991-01-31
HU212277B (en) 1996-04-29
FI884877A7 (fi) 1988-10-21
MX9203130A (es) 1992-07-01
JPH07147989A (ja) 1995-06-13
DK2688D0 (da) 1988-01-05
ATE92966T1 (de) 1993-08-15
HUT47979A (en) 1989-04-28
KR880701288A (ko) 1988-07-26
US5573763A (en) 1996-11-12
DE3787020D1 (de) 1993-09-16
FI884877A0 (fi) 1988-10-21
EP0307402B1 (en) 1993-08-11
FI884877L (fi) 1988-10-21
EP0307402A1 (en) 1989-03-22
GR870688B (en) 1987-09-07
AU7289087A (en) 1987-12-01
IE60835B1 (en) 1994-08-24
DE3787020T2 (de) 1993-12-16
OA09112A (en) 1991-10-31
MY101209A (en) 1991-08-17
NO880022L (no) 1988-01-05
DK2688A (da) 1988-03-07
IL82400A0 (en) 1987-11-30
NO880022D0 (no) 1988-01-05
EP0307402A4 (en) 1990-02-22
IE870994L (en) 1987-11-06
JPH01502397A (ja) 1989-08-24
KR960004453B1 (en) 1996-04-06
CA1334942C (en) 1995-03-28
WO1987006954A1 (en) 1987-11-19

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20041102