ES2054797T3 - Soportes policationicos para purificar, separar e hibridar acidos nucleicos. - Google Patents
Soportes policationicos para purificar, separar e hibridar acidos nucleicos.Info
- Publication number
- ES2054797T3 ES2054797T3 ES88301839T ES88301839T ES2054797T3 ES 2054797 T3 ES2054797 T3 ES 2054797T3 ES 88301839 T ES88301839 T ES 88301839T ES 88301839 T ES88301839 T ES 88301839T ES 2054797 T3 ES2054797 T3 ES 2054797T3
- Authority
- ES
- Spain
- Prior art keywords
- nucleic acids
- supports
- policationic
- purify
- separate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
- C07H1/06—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Cleaning Or Drying Semiconductors (AREA)
- Detergent Compositions (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Cleaning And De-Greasing Of Metallic Materials By Chemical Methods (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Extraction Or Liquid Replacement (AREA)
Abstract
SE DESCRIBE EL EMPLEO DE SOPORTES SOLIDOS POLICATIONICOS EN LA PURIFICACION DE ACIDOS NUCLEICOS A PARTIR DE SOLUCIONES QUE CONTIENEN CONTAMINANTES. LOS ACIDOS NUCLEICOS SE UNEN DE FORMA NO-COVALENTE AL SOPORTE SIN QUE SE PRODUZCA UNA UNION IMPORTANTE DE LOS CONTAMINANTES, PERMITIENDO ASI SU SEPARACION DE ELLOS. LOS ACIDOS NUCLEICOS UNIDOS AL SOPORTE SE PUEDEN RECUPERAR DE EL. TAMBIEN SE DESCRIBE EL EMPLEO DE LOS SOPORTES COMO MEDIO PARA SEPARAR POLINUCLEOTIDOS DE ELLOS CON UNA SONDA NUCLEOTIDICA A PARTIR DE LA SONDA NO HIBRIDIZADA. SE DESCRIBEN ENSAYOS PARA SECUENCIAS NUCLEOTIDICAS, QUE EMPLEAN ESTE PROCEDIMIENTO DE SEPARACION.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2086687A | 1987-03-02 | 1987-03-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2054797T3 true ES2054797T3 (es) | 1994-08-16 |
Family
ID=21801014
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES88301839T Expired - Lifetime ES2054797T3 (es) | 1987-03-02 | 1988-03-02 | Soportes policationicos para purificar, separar e hibridar acidos nucleicos. |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0281390B1 (es) |
| JP (1) | JP2862547B2 (es) |
| KR (1) | KR960000479B1 (es) |
| AT (1) | ATE107654T1 (es) |
| CA (1) | CA1339446C (es) |
| DE (1) | DE3850273T2 (es) |
| DK (1) | DK607588A (es) |
| ES (1) | ES2054797T3 (es) |
| FI (1) | FI885022A0 (es) |
| NO (1) | NO884847L (es) |
| PT (1) | PT86881A (es) |
| WO (1) | WO1988006633A1 (es) |
Families Citing this family (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5310650A (en) * | 1986-09-29 | 1994-05-10 | Abbott Laboratoires | Method and device for improved reaction kinetics in nucleic acid hybridizations |
| US6270961B1 (en) * | 1987-04-01 | 2001-08-07 | Hyseq, Inc. | Methods and apparatus for DNA sequencing and DNA identification |
| US5512439A (en) * | 1988-11-21 | 1996-04-30 | Dynal As | Oligonucleotide-linked magnetic particles and uses thereof |
| EP0446260B1 (en) * | 1988-11-21 | 1994-03-02 | Dynal A.S. | Nucleic acid probes |
| CA2012984A1 (en) * | 1989-03-27 | 1990-09-27 | Frank W. Hobbs Jr. | Process for rapid nucleic acid detection by incorporating a reporter moiety into amplified target nucleic acid followed by affinity capture |
| DE69027910T2 (de) * | 1989-05-31 | 1997-02-20 | Amoco Corp | Nukleinsäuresonden zum Nachweis von Chlamydia trachomatis und Chlamydia psittaci |
| CA1337639C (en) * | 1989-08-01 | 1995-11-28 | Joseph Eugene Celebuski | Dna probe assay using neutrally charged probe strands |
| US5523231A (en) * | 1990-02-13 | 1996-06-04 | Amersham International Plc | Method to isolate macromolecules using magnetically attractable beads which do not specifically bind the macromolecules |
| GB9003253D0 (en) * | 1990-02-13 | 1990-04-11 | Amersham Int Plc | Precipitating polymers |
| FR2666096B1 (fr) * | 1990-08-21 | 1993-12-31 | Sfri Sa | Nouveau procede de dosage d'acide desoxyribonucleique present en position extracellulaire dans un milieu. |
| DE4041080A1 (de) | 1990-12-21 | 1992-06-25 | Behringwerke Ag | Verfahren zur bestimmung eines analyten |
| US6100099A (en) | 1994-09-06 | 2000-08-08 | Abbott Laboratories | Test strip having a diagonal array of capture spots |
| US6093538A (en) * | 1992-05-06 | 2000-07-25 | Gen-Probe Incorporated | Nucleic acid probes to ureaplasma |
| WO1994028174A1 (en) * | 1993-05-24 | 1994-12-08 | Amoco Corporation | Nucleic acid probes for bacteria of the genus legionella |
| GB9314249D0 (en) * | 1993-07-09 | 1993-08-18 | Proofname Ltd | Purification method and apparatus |
| US5438127A (en) * | 1993-09-27 | 1995-08-01 | Becton Dickinson And Company | DNA purification by solid phase extraction using a PCl3 modified glass fiber membrane |
| US5610287A (en) * | 1993-12-06 | 1997-03-11 | Molecular Tool, Inc. | Method for immobilizing nucleic acid molecules |
| DE69535240T2 (de) * | 1994-10-28 | 2007-06-06 | Gen-Probe Inc., San Diego | Zusammensetzungen und Verfahren für die gleichzeitige Detektion und Quantifizierung von einer Mehrheit spezifischer Nuklein Säure Sequenzen |
| US5635349A (en) * | 1994-12-02 | 1997-06-03 | Tularik, Inc. | High-throughput screening assay for inhibitors of nucleic acid polymerases |
| GB9425138D0 (en) | 1994-12-12 | 1995-02-08 | Dynal As | Isolation of nucleic acid |
| KR100463475B1 (ko) | 1995-06-08 | 2005-06-22 | 로셰 디아그노스틱스 게엠베하 | 자기성피그먼트 |
| DE19520398B4 (de) * | 1995-06-08 | 2009-04-16 | Roche Diagnostics Gmbh | Magnetisches Pigment |
| DE19534122A1 (de) * | 1995-09-14 | 1997-03-20 | Behringwerke Ag | Homogener Gensondentest mit einem gegen das Label gerichteten Rezeptor |
| US5783686A (en) * | 1995-09-15 | 1998-07-21 | Beckman Instruments, Inc. | Method for purifying nucleic acids from heterogenous mixtures |
| US5795784A (en) | 1996-09-19 | 1998-08-18 | Abbott Laboratories | Method of performing a process for determining an item of interest in a sample |
| US5856194A (en) | 1996-09-19 | 1999-01-05 | Abbott Laboratories | Method for determination of item of interest in a sample |
| DE19736366A1 (de) | 1997-08-21 | 1999-02-25 | Ernst Prof Dr Bayer | Verfahren zur Isolierung von anionischen organischen Verbindungen aus wäßrigen Systemen mit kationischen Polymernanopartikeln |
| US7632651B2 (en) | 1997-09-15 | 2009-12-15 | Mds Analytical Technologies (Us) Inc. | Molecular modification assays |
| US7070921B2 (en) | 2000-04-28 | 2006-07-04 | Molecular Devices Corporation | Molecular modification assays |
| US5817798A (en) * | 1997-09-17 | 1998-10-06 | Abbott Laboratories | Rapid RNA isolation procedure in the presence of a transition metal ion |
| DE19743518A1 (de) * | 1997-10-01 | 1999-04-15 | Roche Diagnostics Gmbh | Automatisierbare universell anwendbare Probenvorbereitungsmethode |
| GB2346615B (en) | 1998-11-17 | 2003-10-15 | Cambridge Molecular Tech | Isolating nucleic acid |
| DE19937607A1 (de) * | 1999-08-09 | 2001-02-15 | Bilatec Ges Zur Entwicklung Bi | Reagenzienkit zur Isolierung von Nukleinsäuren |
| DE10006590B4 (de) * | 2000-02-11 | 2007-10-18 | Qiagen North American Holdings, Inc. | Verwendung funktionalisierter Membranen bzw. Matrizes zur Aufreinigung von Nukleinsäuren sowie entsprechende Verfahren |
| JP4519247B2 (ja) * | 2000-03-09 | 2010-08-04 | シスメックス株式会社 | 核酸の抽出精製用試薬 |
| US6692700B2 (en) | 2001-02-14 | 2004-02-17 | Handylab, Inc. | Heat-reduction methods and systems related to microfluidic devices |
| WO2004060278A2 (en) | 2002-12-06 | 2004-07-22 | Isis Pharmaceuticals, Inc. | Methods for rapid identification of pathogens in humans and animals |
| US20030027135A1 (en) | 2001-03-02 | 2003-02-06 | Ecker David J. | Method for rapid detection and identification of bioagents |
| US7666588B2 (en) | 2001-03-02 | 2010-02-23 | Ibis Biosciences, Inc. | Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy |
| US20040121309A1 (en) | 2002-12-06 | 2004-06-24 | Ecker David J. | Methods for rapid detection and identification of bioagents in blood, bodily fluids, and bodily tissues |
| US7718354B2 (en) | 2001-03-02 | 2010-05-18 | Ibis Biosciences, Inc. | Methods for rapid identification of pathogens in humans and animals |
| US7829025B2 (en) | 2001-03-28 | 2010-11-09 | Venture Lending & Leasing Iv, Inc. | Systems and methods for thermal actuation of microfluidic devices |
| US6852287B2 (en) | 2001-09-12 | 2005-02-08 | Handylab, Inc. | Microfluidic devices having a reduced number of input and output connections |
| US8895311B1 (en) | 2001-03-28 | 2014-11-25 | Handylab, Inc. | Methods and systems for control of general purpose microfluidic devices |
| US7010391B2 (en) | 2001-03-28 | 2006-03-07 | Handylab, Inc. | Methods and systems for control of microfluidic devices |
| US7217510B2 (en) | 2001-06-26 | 2007-05-15 | Isis Pharmaceuticals, Inc. | Methods for providing bacterial bioagent characterizing information |
| CN1617938A (zh) | 2002-01-16 | 2005-05-18 | 戴诺生物技术有限公司 | 从单个样品中分离核酸和蛋白质的方法 |
| SE0202074D0 (sv) * | 2002-06-28 | 2002-07-02 | Amersham Biosciences Ab | Isolation of nucleic acids |
| JP4437218B2 (ja) * | 2002-11-26 | 2010-03-24 | 日生バイオ株式会社 | Rna−プロタミン複合体、その製造方法およびそれを含む健康食品 |
| US7601491B2 (en) | 2003-02-06 | 2009-10-13 | Becton, Dickinson And Company | Pretreatment method for extraction of nucleic acid from biological samples and kits therefor |
| US8046171B2 (en) | 2003-04-18 | 2011-10-25 | Ibis Biosciences, Inc. | Methods and apparatus for genetic evaluation |
| WO2005011867A2 (en) | 2003-07-31 | 2005-02-10 | Handylab, Inc. | Processing particle-containing samples |
| US7666592B2 (en) | 2004-02-18 | 2010-02-23 | Ibis Biosciences, Inc. | Methods for concurrent identification and quantification of an unknown bioagent |
| US8119336B2 (en) | 2004-03-03 | 2012-02-21 | Ibis Biosciences, Inc. | Compositions for use in identification of alphaviruses |
| ES2572382T3 (es) * | 2004-05-03 | 2016-05-31 | Handylab Inc | Un dispositivo microfluídico para el procesamiento de muestras que contienen polinucleótidos |
| US8852862B2 (en) | 2004-05-03 | 2014-10-07 | Handylab, Inc. | Method for processing polynucleotide-containing samples |
| ES2641832T3 (es) | 2004-05-24 | 2017-11-14 | Ibis Biosciences, Inc. | Espectrometría de masas con filtración de iones selectiva por establecimiento de umbrales digitales |
| US7811753B2 (en) | 2004-07-14 | 2010-10-12 | Ibis Biosciences, Inc. | Methods for repairing degraded DNA |
| DE102005060392A1 (de) | 2005-12-16 | 2007-06-21 | Süd-Chemie AG | Verfahren zur Abtrennung von Proteinen aus flüssigen Medien |
| US7998708B2 (en) | 2006-03-24 | 2011-08-16 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
| US10900066B2 (en) | 2006-03-24 | 2021-01-26 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
| DK3088083T3 (en) | 2006-03-24 | 2018-11-26 | Handylab Inc | Method of carrying out PCR down a multi-track cartridge |
| US11806718B2 (en) | 2006-03-24 | 2023-11-07 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
| US20090275486A1 (en) * | 2006-05-16 | 2009-11-05 | Nurith Kurn | Nucleic acid separation and purification method based on reversible charge interactions |
| US9149473B2 (en) | 2006-09-14 | 2015-10-06 | Ibis Biosciences, Inc. | Targeted whole genome amplification method for identification of pathogens |
| US8709787B2 (en) | 2006-11-14 | 2014-04-29 | Handylab, Inc. | Microfluidic cartridge and method of using same |
| WO2008060604A2 (en) | 2006-11-14 | 2008-05-22 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
| EP2126132B1 (en) | 2007-02-23 | 2013-03-20 | Ibis Biosciences, Inc. | Methods for rapid foresnsic dna analysis |
| CA2629589C (en) | 2007-04-20 | 2016-03-29 | F.Hoffmann-La Roche Ag | Isolation and purification of nucleic acid molecules with a solid phase |
| WO2008151023A2 (en) | 2007-06-01 | 2008-12-11 | Ibis Biosciences, Inc. | Methods and compositions for multiple displacement amplification of nucleic acids |
| US8133671B2 (en) | 2007-07-13 | 2012-03-13 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
| US8287820B2 (en) | 2007-07-13 | 2012-10-16 | Handylab, Inc. | Automated pipetting apparatus having a combined liquid pump and pipette head system |
| AU2008276211B2 (en) | 2007-07-13 | 2015-01-22 | Handylab, Inc. | Polynucleotide capture materials, and methods of using same |
| US9618139B2 (en) | 2007-07-13 | 2017-04-11 | Handylab, Inc. | Integrated heater and magnetic separator |
| US8182763B2 (en) | 2007-07-13 | 2012-05-22 | Handylab, Inc. | Rack for sample tubes and reagent holders |
| US9186677B2 (en) | 2007-07-13 | 2015-11-17 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
| US8105783B2 (en) | 2007-07-13 | 2012-01-31 | Handylab, Inc. | Microfluidic cartridge |
| JP4545200B2 (ja) * | 2008-02-04 | 2010-09-15 | 積水メディカル株式会社 | 核酸固定用磁性粒子 |
| USD787087S1 (en) | 2008-07-14 | 2017-05-16 | Handylab, Inc. | Housing |
| WO2010033625A1 (en) | 2008-09-16 | 2010-03-25 | Ibis Biosciences, Inc. | Microplate handling systems and related computer program products and methods |
| US8148163B2 (en) | 2008-09-16 | 2012-04-03 | Ibis Biosciences, Inc. | Sample processing units, systems, and related methods |
| EP2396803A4 (en) | 2009-02-12 | 2016-10-26 | Ibis Biosciences Inc | IONIZATION PROBE ASSEMBLIES |
| EP2454000A4 (en) | 2009-07-17 | 2016-08-10 | Ibis Biosciences Inc | SYSTEMS FOR IDENTIFYING BIOLOGICAL SUBSTANCES |
| US8950604B2 (en) | 2009-07-17 | 2015-02-10 | Ibis Biosciences, Inc. | Lift and mount apparatus |
| EP2488656B1 (en) | 2009-10-15 | 2015-06-03 | Ibis Biosciences, Inc. | Multiple displacement amplification |
| ES2769028T3 (es) | 2011-04-15 | 2020-06-24 | Becton Dickinson Co | Termociclador microfluídico de barrido en tiempo real |
| USD692162S1 (en) | 2011-09-30 | 2013-10-22 | Becton, Dickinson And Company | Single piece reagent holder |
| ES2645966T3 (es) | 2011-09-30 | 2017-12-11 | Becton, Dickinson And Company | Tira reactiva unificada |
| CN104040238B (zh) | 2011-11-04 | 2017-06-27 | 汉迪拉布公司 | 多核苷酸样品制备装置 |
| AU2013214849B2 (en) | 2012-02-03 | 2016-09-01 | Becton, Dickinson And Company | External files for distribution of molecular diagnostic tests and determination of compatibility between tests |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8203102A (nl) * | 1982-08-04 | 1984-03-01 | Katholieke Universiteit Facult | Papier voor rna-blotting; werkwijze voor het maken daarvan; toepassingen van het papier. |
| US4554088A (en) * | 1983-05-12 | 1985-11-19 | Advanced Magnetics Inc. | Magnetic particles for use in separations |
| US4672040A (en) * | 1983-05-12 | 1987-06-09 | Advanced Magnetics, Inc. | Magnetic particles for use in separations |
| US4652517A (en) * | 1984-06-11 | 1987-03-24 | Diagnostic Research Limited Partnership | Methods for the in vitro detection and identification of unknown pathogens or genetic entities |
| EP0189280A3 (en) * | 1985-01-23 | 1987-01-07 | Dekalb-Pfizer Genetics | Qualitative testing for nucleic acid |
| WO1986005519A1 (en) * | 1985-03-15 | 1986-09-25 | James Summerton | Polynucleotide assay reagent and method |
| US4806631A (en) * | 1985-09-30 | 1989-02-21 | Miles Inc. | Immobilization of nucleic acids on solvolyzed nylon supports |
| US4806546A (en) * | 1985-09-30 | 1989-02-21 | Miles Inc. | Immobilization of nucleic acids on derivatized nylon supports |
-
1988
- 1988-03-02 EP EP88301839A patent/EP0281390B1/en not_active Expired - Lifetime
- 1988-03-02 PT PT86881A patent/PT86881A/pt not_active Application Discontinuation
- 1988-03-02 DE DE3850273T patent/DE3850273T2/de not_active Expired - Lifetime
- 1988-03-02 CA CA000560293A patent/CA1339446C/en not_active Expired - Lifetime
- 1988-03-02 FI FI885022A patent/FI885022A0/fi not_active IP Right Cessation
- 1988-03-02 WO PCT/US1988/000550 patent/WO1988006633A1/en not_active Ceased
- 1988-03-02 ES ES88301839T patent/ES2054797T3/es not_active Expired - Lifetime
- 1988-03-02 JP JP63502502A patent/JP2862547B2/ja not_active Expired - Fee Related
- 1988-03-02 AT AT88301839T patent/ATE107654T1/de not_active IP Right Cessation
- 1988-03-02 KR KR1019880701387A patent/KR960000479B1/ko not_active Expired - Fee Related
- 1988-10-31 NO NO884847A patent/NO884847L/no unknown
- 1988-11-01 DK DK607588A patent/DK607588A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DK607588D0 (da) | 1988-11-01 |
| PT86881A (pt) | 1989-03-30 |
| ATE107654T1 (de) | 1994-07-15 |
| DK607588A (da) | 1988-12-28 |
| DE3850273D1 (de) | 1994-07-28 |
| NO884847L (no) | 1988-12-22 |
| AU618951B2 (en) | 1992-01-16 |
| AU1426988A (en) | 1988-09-26 |
| EP0281390A2 (en) | 1988-09-07 |
| FI885022L (fi) | 1988-11-01 |
| EP0281390A3 (en) | 1990-04-25 |
| CA1339446C (en) | 1997-09-09 |
| DE3850273T2 (de) | 1994-09-29 |
| KR960000479B1 (ko) | 1996-01-08 |
| EP0281390B1 (en) | 1994-06-22 |
| NO884847D0 (no) | 1988-10-31 |
| FI885022A7 (fi) | 1988-11-01 |
| FI885022A0 (fi) | 1988-11-01 |
| KR890700682A (ko) | 1989-04-26 |
| JP2862547B2 (ja) | 1999-03-03 |
| JPH01502319A (ja) | 1989-08-17 |
| WO1988006633A1 (en) | 1988-09-07 |
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