ES2054797T3 - Soportes policationicos para purificar, separar e hibridar acidos nucleicos. - Google Patents
Soportes policationicos para purificar, separar e hibridar acidos nucleicos.Info
- Publication number
- ES2054797T3 ES2054797T3 ES88301839T ES88301839T ES2054797T3 ES 2054797 T3 ES2054797 T3 ES 2054797T3 ES 88301839 T ES88301839 T ES 88301839T ES 88301839 T ES88301839 T ES 88301839T ES 2054797 T3 ES2054797 T3 ES 2054797T3
- Authority
- ES
- Spain
- Prior art keywords
- nucleic acids
- supports
- policationic
- purify
- separate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
- C07H1/06—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Cleaning Or Drying Semiconductors (AREA)
- Detergent Compositions (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Cleaning And De-Greasing Of Metallic Materials By Chemical Methods (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Extraction Or Liquid Replacement (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Abstract
SE DESCRIBE EL EMPLEO DE SOPORTES SOLIDOS POLICATIONICOS EN LA PURIFICACION DE ACIDOS NUCLEICOS A PARTIR DE SOLUCIONES QUE CONTIENEN CONTAMINANTES. LOS ACIDOS NUCLEICOS SE UNEN DE FORMA NO-COVALENTE AL SOPORTE SIN QUE SE PRODUZCA UNA UNION IMPORTANTE DE LOS CONTAMINANTES, PERMITIENDO ASI SU SEPARACION DE ELLOS. LOS ACIDOS NUCLEICOS UNIDOS AL SOPORTE SE PUEDEN RECUPERAR DE EL. TAMBIEN SE DESCRIBE EL EMPLEO DE LOS SOPORTES COMO MEDIO PARA SEPARAR POLINUCLEOTIDOS DE ELLOS CON UNA SONDA NUCLEOTIDICA A PARTIR DE LA SONDA NO HIBRIDIZADA. SE DESCRIBEN ENSAYOS PARA SECUENCIAS NUCLEOTIDICAS, QUE EMPLEAN ESTE PROCEDIMIENTO DE SEPARACION.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2086687A | 1987-03-02 | 1987-03-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2054797T3 true ES2054797T3 (es) | 1994-08-16 |
Family
ID=21801014
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES88301839T Expired - Lifetime ES2054797T3 (es) | 1987-03-02 | 1988-03-02 | Soportes policationicos para purificar, separar e hibridar acidos nucleicos. |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0281390B1 (es) |
| JP (1) | JP2862547B2 (es) |
| KR (1) | KR960000479B1 (es) |
| AT (1) | ATE107654T1 (es) |
| CA (1) | CA1339446C (es) |
| DE (1) | DE3850273T2 (es) |
| DK (1) | DK607588A (es) |
| ES (1) | ES2054797T3 (es) |
| FI (1) | FI885022A0 (es) |
| NO (1) | NO884847L (es) |
| PT (1) | PT86881A (es) |
| WO (1) | WO1988006633A1 (es) |
Families Citing this family (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5310650A (en) * | 1986-09-29 | 1994-05-10 | Abbott Laboratoires | Method and device for improved reaction kinetics in nucleic acid hybridizations |
| US6270961B1 (en) * | 1987-04-01 | 2001-08-07 | Hyseq, Inc. | Methods and apparatus for DNA sequencing and DNA identification |
| US5512439A (en) * | 1988-11-21 | 1996-04-30 | Dynal As | Oligonucleotide-linked magnetic particles and uses thereof |
| EP0446260B1 (en) * | 1988-11-21 | 1994-03-02 | Dynal A.S. | Nucleic acid probes |
| CA2012984A1 (en) * | 1989-03-27 | 1990-09-27 | Frank W. Hobbs Jr. | Process for rapid nucleic acid detection by incorporating a reporter moiety into amplified target nucleic acid followed by affinity capture |
| ATE140732T1 (de) * | 1989-05-31 | 1996-08-15 | Amoco Corp | Nukleinsäuresonden zum nachweis von chlamydia trachomatis und chlamydia psittaci |
| CA1337639C (en) * | 1989-08-01 | 1995-11-28 | Joseph Eugene Celebuski | Dna probe assay using neutrally charged probe strands |
| US5523231A (en) * | 1990-02-13 | 1996-06-04 | Amersham International Plc | Method to isolate macromolecules using magnetically attractable beads which do not specifically bind the macromolecules |
| GB9003253D0 (en) * | 1990-02-13 | 1990-04-11 | Amersham Int Plc | Precipitating polymers |
| FR2666096B1 (fr) * | 1990-08-21 | 1993-12-31 | Sfri Sa | Nouveau procede de dosage d'acide desoxyribonucleique present en position extracellulaire dans un milieu. |
| DE4041080A1 (de) | 1990-12-21 | 1992-06-25 | Behringwerke Ag | Verfahren zur bestimmung eines analyten |
| US6100099A (en) | 1994-09-06 | 2000-08-08 | Abbott Laboratories | Test strip having a diagonal array of capture spots |
| US6093538A (en) * | 1992-05-06 | 2000-07-25 | Gen-Probe Incorporated | Nucleic acid probes to ureaplasma |
| WO1994028174A1 (en) * | 1993-05-24 | 1994-12-08 | Amoco Corporation | Nucleic acid probes for bacteria of the genus legionella |
| GB9314249D0 (en) * | 1993-07-09 | 1993-08-18 | Proofname Ltd | Purification method and apparatus |
| US5438127A (en) * | 1993-09-27 | 1995-08-01 | Becton Dickinson And Company | DNA purification by solid phase extraction using a PCl3 modified glass fiber membrane |
| US5610287A (en) * | 1993-12-06 | 1997-03-11 | Molecular Tool, Inc. | Method for immobilizing nucleic acid molecules |
| EP0709466B1 (en) * | 1994-10-28 | 2006-09-27 | Gen-Probe Incorporated | Compositions and methods for the simultaneous detection and quantification of multiple specific nucleic acid sequences |
| US5635349A (en) * | 1994-12-02 | 1997-06-03 | Tularik, Inc. | High-throughput screening assay for inhibitors of nucleic acid polymerases |
| GB9425138D0 (en) | 1994-12-12 | 1995-02-08 | Dynal As | Isolation of nucleic acid |
| KR100463475B1 (ko) | 1995-06-08 | 2005-06-22 | 로셰 디아그노스틱스 게엠베하 | 자기성피그먼트 |
| DE19520398B4 (de) | 1995-06-08 | 2009-04-16 | Roche Diagnostics Gmbh | Magnetisches Pigment |
| DE19534122A1 (de) * | 1995-09-14 | 1997-03-20 | Behringwerke Ag | Homogener Gensondentest mit einem gegen das Label gerichteten Rezeptor |
| US5783686A (en) * | 1995-09-15 | 1998-07-21 | Beckman Instruments, Inc. | Method for purifying nucleic acids from heterogenous mixtures |
| US5856194A (en) | 1996-09-19 | 1999-01-05 | Abbott Laboratories | Method for determination of item of interest in a sample |
| US5795784A (en) | 1996-09-19 | 1998-08-18 | Abbott Laboratories | Method of performing a process for determining an item of interest in a sample |
| DE19736366A1 (de) * | 1997-08-21 | 1999-02-25 | Ernst Prof Dr Bayer | Verfahren zur Isolierung von anionischen organischen Verbindungen aus wäßrigen Systemen mit kationischen Polymernanopartikeln |
| US7070921B2 (en) | 2000-04-28 | 2006-07-04 | Molecular Devices Corporation | Molecular modification assays |
| US7632651B2 (en) | 1997-09-15 | 2009-12-15 | Mds Analytical Technologies (Us) Inc. | Molecular modification assays |
| US5817798A (en) * | 1997-09-17 | 1998-10-06 | Abbott Laboratories | Rapid RNA isolation procedure in the presence of a transition metal ion |
| DE19743518A1 (de) | 1997-10-01 | 1999-04-15 | Roche Diagnostics Gmbh | Automatisierbare universell anwendbare Probenvorbereitungsmethode |
| GB2346615B (en) | 1998-11-17 | 2003-10-15 | Cambridge Molecular Tech | Isolating nucleic acid |
| DE19937607A1 (de) * | 1999-08-09 | 2001-02-15 | Bilatec Ges Zur Entwicklung Bi | Reagenzienkit zur Isolierung von Nukleinsäuren |
| DE10006590B4 (de) * | 2000-02-11 | 2007-10-18 | Qiagen North American Holdings, Inc. | Verwendung funktionalisierter Membranen bzw. Matrizes zur Aufreinigung von Nukleinsäuren sowie entsprechende Verfahren |
| JP4519247B2 (ja) * | 2000-03-09 | 2010-08-04 | シスメックス株式会社 | 核酸の抽出精製用試薬 |
| US6692700B2 (en) | 2001-02-14 | 2004-02-17 | Handylab, Inc. | Heat-reduction methods and systems related to microfluidic devices |
| US7666588B2 (en) | 2001-03-02 | 2010-02-23 | Ibis Biosciences, Inc. | Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy |
| US20040121309A1 (en) | 2002-12-06 | 2004-06-24 | Ecker David J. | Methods for rapid detection and identification of bioagents in blood, bodily fluids, and bodily tissues |
| US20030027135A1 (en) | 2001-03-02 | 2003-02-06 | Ecker David J. | Method for rapid detection and identification of bioagents |
| US7718354B2 (en) | 2001-03-02 | 2010-05-18 | Ibis Biosciences, Inc. | Methods for rapid identification of pathogens in humans and animals |
| US7010391B2 (en) | 2001-03-28 | 2006-03-07 | Handylab, Inc. | Methods and systems for control of microfluidic devices |
| US7829025B2 (en) | 2001-03-28 | 2010-11-09 | Venture Lending & Leasing Iv, Inc. | Systems and methods for thermal actuation of microfluidic devices |
| US6852287B2 (en) | 2001-09-12 | 2005-02-08 | Handylab, Inc. | Microfluidic devices having a reduced number of input and output connections |
| US8895311B1 (en) | 2001-03-28 | 2014-11-25 | Handylab, Inc. | Methods and systems for control of general purpose microfluidic devices |
| US7217510B2 (en) | 2001-06-26 | 2007-05-15 | Isis Pharmaceuticals, Inc. | Methods for providing bacterial bioagent characterizing information |
| JP2005538929A (ja) | 2002-01-16 | 2005-12-22 | ダイナル バイオテック エイエスエイ | 単一サンプルからの核酸及びタンパク質の単離方法 |
| SE0202074D0 (sv) * | 2002-06-28 | 2002-07-02 | Amersham Biosciences Ab | Isolation of nucleic acids |
| JP4437218B2 (ja) * | 2002-11-26 | 2010-03-24 | 日生バイオ株式会社 | Rna−プロタミン複合体、その製造方法およびそれを含む健康食品 |
| JP2006516193A (ja) | 2002-12-06 | 2006-06-29 | アイシス・ファーマシューティカルス・インコーポレーテッド | ヒトおよび動物における病原体の迅速な同定方法 |
| US7601491B2 (en) | 2003-02-06 | 2009-10-13 | Becton, Dickinson And Company | Pretreatment method for extraction of nucleic acid from biological samples and kits therefor |
| US8046171B2 (en) | 2003-04-18 | 2011-10-25 | Ibis Biosciences, Inc. | Methods and apparatus for genetic evaluation |
| EP3718635A1 (en) | 2003-07-31 | 2020-10-07 | Handylab, Inc. | Processing particle-containing samples |
| US7666592B2 (en) | 2004-02-18 | 2010-02-23 | Ibis Biosciences, Inc. | Methods for concurrent identification and quantification of an unknown bioagent |
| US8119336B2 (en) | 2004-03-03 | 2012-02-21 | Ibis Biosciences, Inc. | Compositions for use in identification of alphaviruses |
| US8852862B2 (en) | 2004-05-03 | 2014-10-07 | Handylab, Inc. | Method for processing polynucleotide-containing samples |
| ES2553097T3 (es) * | 2004-05-03 | 2015-12-04 | Handylab, Inc. | Procesamiento de muestras que contienen polinucleótidos |
| EP2458619B1 (en) | 2004-05-24 | 2017-08-02 | Ibis Biosciences, Inc. | Mass spectrometry with selective ion filtration by digital thresholding |
| US7811753B2 (en) | 2004-07-14 | 2010-10-12 | Ibis Biosciences, Inc. | Methods for repairing degraded DNA |
| DE102005060392A1 (de) | 2005-12-16 | 2007-06-21 | Süd-Chemie AG | Verfahren zur Abtrennung von Proteinen aus flüssigen Medien |
| US7998708B2 (en) | 2006-03-24 | 2011-08-16 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
| US10900066B2 (en) | 2006-03-24 | 2021-01-26 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
| US11806718B2 (en) | 2006-03-24 | 2023-11-07 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
| ES2692380T3 (es) | 2006-03-24 | 2018-12-03 | Handylab, Inc. | Método para realizar PCR con un cartucho con varias pistas |
| CA2652052A1 (en) * | 2006-05-16 | 2007-11-29 | Nugen Technologies, Inc. | Nucleic acid separation and purification method based on reversible charge interactions |
| JP5420412B2 (ja) | 2006-09-14 | 2014-02-19 | アイビス バイオサイエンシズ インコーポレイティッド | 病原体の同定のための標的全ゲノム増幅方法 |
| WO2008060604A2 (en) | 2006-11-14 | 2008-05-22 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
| US8765076B2 (en) | 2006-11-14 | 2014-07-01 | Handylab, Inc. | Microfluidic valve and method of making same |
| JP5680304B2 (ja) | 2007-02-23 | 2015-03-04 | アイビス バイオサイエンシズ インコーポレイティッド | 迅速な法医学的dna分析法 |
| CA2629589C (en) | 2007-04-20 | 2016-03-29 | F.Hoffmann-La Roche Ag | Isolation and purification of nucleic acid molecules with a solid phase |
| US9598724B2 (en) | 2007-06-01 | 2017-03-21 | Ibis Biosciences, Inc. | Methods and compositions for multiple displacement amplification of nucleic acids |
| US8105783B2 (en) | 2007-07-13 | 2012-01-31 | Handylab, Inc. | Microfluidic cartridge |
| US8133671B2 (en) | 2007-07-13 | 2012-03-13 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
| AU2008276211B2 (en) | 2007-07-13 | 2015-01-22 | Handylab, Inc. | Polynucleotide capture materials, and methods of using same |
| US8182763B2 (en) | 2007-07-13 | 2012-05-22 | Handylab, Inc. | Rack for sample tubes and reagent holders |
| US9186677B2 (en) | 2007-07-13 | 2015-11-17 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
| US9618139B2 (en) | 2007-07-13 | 2017-04-11 | Handylab, Inc. | Integrated heater and magnetic separator |
| US8287820B2 (en) | 2007-07-13 | 2012-10-16 | Handylab, Inc. | Automated pipetting apparatus having a combined liquid pump and pipette head system |
| JP4545200B2 (ja) * | 2008-02-04 | 2010-09-15 | 積水メディカル株式会社 | 核酸固定用磁性粒子 |
| USD787087S1 (en) | 2008-07-14 | 2017-05-16 | Handylab, Inc. | Housing |
| EP2344893B1 (en) | 2008-09-16 | 2014-10-15 | Ibis Biosciences, Inc. | Microplate handling systems and methods |
| US8148163B2 (en) | 2008-09-16 | 2012-04-03 | Ibis Biosciences, Inc. | Sample processing units, systems, and related methods |
| EP2396803A4 (en) | 2009-02-12 | 2016-10-26 | Ibis Biosciences Inc | IONIZATION PROBE ASSEMBLIES |
| US9194877B2 (en) | 2009-07-17 | 2015-11-24 | Ibis Biosciences, Inc. | Systems for bioagent indentification |
| US8950604B2 (en) | 2009-07-17 | 2015-02-10 | Ibis Biosciences, Inc. | Lift and mount apparatus |
| ES2628739T3 (es) | 2009-10-15 | 2017-08-03 | Ibis Biosciences, Inc. | Amplificación por desplazamiento múltiple |
| JP6088487B2 (ja) | 2011-04-15 | 2017-03-01 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | 走査リアルタイムマイクロ流体熱サイクラーと同期熱サイクリング及び走査光学検出の方法 |
| RU2622432C2 (ru) | 2011-09-30 | 2017-06-15 | Бектон, Дикинсон Энд Компани | Унифицированная полоска для реактивов |
| USD692162S1 (en) | 2011-09-30 | 2013-10-22 | Becton, Dickinson And Company | Single piece reagent holder |
| WO2013067202A1 (en) | 2011-11-04 | 2013-05-10 | Handylab, Inc. | Polynucleotide sample preparation device |
| AU2013214849B2 (en) | 2012-02-03 | 2016-09-01 | Becton, Dickinson And Company | External files for distribution of molecular diagnostic tests and determination of compatibility between tests |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8203102A (nl) * | 1982-08-04 | 1984-03-01 | Katholieke Universiteit Facult | Papier voor rna-blotting; werkwijze voor het maken daarvan; toepassingen van het papier. |
| US4672040A (en) * | 1983-05-12 | 1987-06-09 | Advanced Magnetics, Inc. | Magnetic particles for use in separations |
| US4554088A (en) * | 1983-05-12 | 1985-11-19 | Advanced Magnetics Inc. | Magnetic particles for use in separations |
| US4652517A (en) * | 1984-06-11 | 1987-03-24 | Diagnostic Research Limited Partnership | Methods for the in vitro detection and identification of unknown pathogens or genetic entities |
| EP0189280A3 (en) * | 1985-01-23 | 1987-01-07 | Dekalb-Pfizer Genetics | Qualitative testing for nucleic acid |
| JP3022967B2 (ja) * | 1985-03-15 | 2000-03-21 | アンチバイラルズ インコーポレイテッド | 立体規則性ポリヌクレオチド結合ポリマー |
| US4806546A (en) * | 1985-09-30 | 1989-02-21 | Miles Inc. | Immobilization of nucleic acids on derivatized nylon supports |
| US4806631A (en) * | 1985-09-30 | 1989-02-21 | Miles Inc. | Immobilization of nucleic acids on solvolyzed nylon supports |
-
1988
- 1988-03-02 DE DE3850273T patent/DE3850273T2/de not_active Expired - Lifetime
- 1988-03-02 KR KR1019880701387A patent/KR960000479B1/ko not_active Expired - Fee Related
- 1988-03-02 FI FI885022A patent/FI885022A0/fi not_active IP Right Cessation
- 1988-03-02 PT PT86881A patent/PT86881A/pt not_active Application Discontinuation
- 1988-03-02 AT AT88301839T patent/ATE107654T1/de not_active IP Right Cessation
- 1988-03-02 EP EP88301839A patent/EP0281390B1/en not_active Expired - Lifetime
- 1988-03-02 WO PCT/US1988/000550 patent/WO1988006633A1/en not_active Ceased
- 1988-03-02 CA CA000560293A patent/CA1339446C/en not_active Expired - Lifetime
- 1988-03-02 ES ES88301839T patent/ES2054797T3/es not_active Expired - Lifetime
- 1988-03-02 JP JP63502502A patent/JP2862547B2/ja not_active Expired - Fee Related
- 1988-10-31 NO NO884847A patent/NO884847L/no unknown
- 1988-11-01 DK DK607588A patent/DK607588A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE3850273D1 (de) | 1994-07-28 |
| WO1988006633A1 (en) | 1988-09-07 |
| JP2862547B2 (ja) | 1999-03-03 |
| EP0281390A2 (en) | 1988-09-07 |
| NO884847L (no) | 1988-12-22 |
| AU618951B2 (en) | 1992-01-16 |
| ATE107654T1 (de) | 1994-07-15 |
| FI885022L (fi) | 1988-11-01 |
| DK607588D0 (da) | 1988-11-01 |
| NO884847D0 (no) | 1988-10-31 |
| KR960000479B1 (ko) | 1996-01-08 |
| DK607588A (da) | 1988-12-28 |
| DE3850273T2 (de) | 1994-09-29 |
| FI885022A7 (fi) | 1988-11-01 |
| KR890700682A (ko) | 1989-04-26 |
| JPH01502319A (ja) | 1989-08-17 |
| PT86881A (pt) | 1989-03-30 |
| EP0281390A3 (en) | 1990-04-25 |
| AU1426988A (en) | 1988-09-26 |
| EP0281390B1 (en) | 1994-06-22 |
| CA1339446C (en) | 1997-09-09 |
| FI885022A0 (fi) | 1988-11-01 |
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