ES2114186T3 - Conjugados de lipido y polimero y liposomas. - Google Patents

Conjugados de lipido y polimero y liposomas.

Info

Publication number
ES2114186T3
ES2114186T3 ES94910813T ES94910813T ES2114186T3 ES 2114186 T3 ES2114186 T3 ES 2114186T3 ES 94910813 T ES94910813 T ES 94910813T ES 94910813 T ES94910813 T ES 94910813T ES 2114186 T3 ES2114186 T3 ES 2114186T3
Authority
ES
Spain
Prior art keywords
liposomes
lipid
conjugate
polymer conjugates
lipido
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94910813T
Other languages
English (en)
Inventor
Samuel Zalipsky
Martin C Woodle
Danilo D Lasic
Francis J Martin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Sequus Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sequus Pharmaceuticals Inc filed Critical Sequus Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2114186T3 publication Critical patent/ES2114186T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Polyamides (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

Abstract

UN CONJUGADO DE LIPIDO-POLIMERO PARA USAR EN LA FORMACION DE LIPOSOMAS DE CIRCULACION LARGA. EL CONJUGADO COMPRENDE UN LIPIDO DE FORMACION DE VESICULA QUE TIENE COVALENTEMENTE FIJADO A SU GRUPO DE CABEZA POLAR, UNO DE LOS POLIMEROS: POLIVINILPIRROLIDONA, POLIVINILMETILETER, POLIHIDROXIPROPILMETACRILATO, POLIHIDROXIPROPILMETACRILMIDA, POLIHIDROXIETILACRILATO, POLIMETACRILAMIDA, POLIMETILACRILAMIDA, POLIMETILOXAZOLINA, POLIETILOXAZOLINA, POLIHIDROXIPROPILOXAZOLINA, O POLIASPARTAMIDA. TAMBIEN SE PREVE UN METODO PARA PREPARAR LIPOSOMAS QUE CONTIENEN EL CONJUGADO LIPIDO-POLIMERO.
ES94910813T 1993-03-03 1994-03-02 Conjugados de lipido y polimero y liposomas. Expired - Lifetime ES2114186T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/025,602 US5395619A (en) 1993-03-03 1993-03-03 Lipid-polymer conjugates and liposomes
PCT/US1994/002271 WO1994020073A1 (en) 1993-03-03 1994-03-02 Lipid-polymer conjugates and liposomes

Publications (1)

Publication Number Publication Date
ES2114186T3 true ES2114186T3 (es) 1998-05-16

Family

ID=21827009

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94910813T Expired - Lifetime ES2114186T3 (es) 1993-03-03 1994-03-02 Conjugados de lipido y polimero y liposomas.

Country Status (10)

Country Link
US (2) US5395619A (es)
EP (1) EP0688207B1 (es)
JP (1) JP3066437B2 (es)
AT (1) ATE162710T1 (es)
AU (1) AU6357594A (es)
CA (1) CA2156901C (es)
DE (1) DE69408304T2 (es)
DK (1) DK0688207T3 (es)
ES (1) ES2114186T3 (es)
WO (1) WO1994020073A1 (es)

Families Citing this family (463)

* Cited by examiner, † Cited by third party
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US5395619A (en) 1995-03-07
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ATE162710T1 (de) 1998-02-15
DE69408304D1 (de) 1998-03-05
WO1994020073A1 (en) 1994-09-15
CA2156901C (en) 2001-12-18
EP0688207A1 (en) 1995-12-27
CA2156901A1 (en) 1994-09-15
DE69408304T2 (de) 1998-08-20
DK0688207T3 (da) 1998-04-06
AU6357594A (en) 1994-09-26
US5631018A (en) 1997-05-20
JP3066437B2 (ja) 2000-07-17

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