ES2191183T3 - Derivados 6,6- o 6,7-biciclicos que contienen pirido o pirimido sustituidos. - Google Patents

Derivados 6,6- o 6,7-biciclicos que contienen pirido o pirimido sustituidos.

Info

Publication number
ES2191183T3
ES2191183T3 ES97929472T ES97929472T ES2191183T3 ES 2191183 T3 ES2191183 T3 ES 2191183T3 ES 97929472 T ES97929472 T ES 97929472T ES 97929472 T ES97929472 T ES 97929472T ES 2191183 T3 ES2191183 T3 ES 2191183T3
Authority
ES
Spain
Prior art keywords
pirimido
derivatives containing
bicycle derivatives
replaced
containing replaced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97929472T
Other languages
English (en)
Inventor
Yuhpyng Liang Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PFIZER
Pfizer Inc
Original Assignee
PFIZER
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PFIZER, Pfizer Inc filed Critical PFIZER
Application granted granted Critical
Publication of ES2191183T3 publication Critical patent/ES2191183T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

LA INVENCION SE REFIERE A COMPUESTOS DE FORMULA (I), EN LA QUE A, B, D, E, K, G, Z, R 3 Y R 5 SE DEFINEN COMO EN LA MEMORIA, Y A LAS SALES FARMACEUTICAMENTE ACEPTABLES DE DICHOS COMPUESTOS. LOS COMPUESTOS (I) SON ANTAGONISTAS DEL FACTOR (HORMONA) DE LIBERACION DE LA CORTICOTROPINA FLC (HLC).
ES97929472T 1996-08-06 1997-07-23 Derivados 6,6- o 6,7-biciclicos que contienen pirido o pirimido sustituidos. Expired - Lifetime ES2191183T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2345396P 1996-08-06 1996-08-06

Publications (1)

Publication Number Publication Date
ES2191183T3 true ES2191183T3 (es) 2003-09-01

Family

ID=21815208

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97929472T Expired - Lifetime ES2191183T3 (es) 1996-08-06 1997-07-23 Derivados 6,6- o 6,7-biciclicos que contienen pirido o pirimido sustituidos.

Country Status (40)

Country Link
US (1) US6492520B1 (es)
EP (1) EP0920429B1 (es)
JP (1) JP3345021B2 (es)
KR (1) KR20000029843A (es)
CN (1) CN1093130C (es)
AP (1) AP1096A (es)
AR (1) AR008829A1 (es)
AT (1) ATE232863T1 (es)
AU (1) AU709203B2 (es)
BG (1) BG103143A (es)
BR (1) BR9710808A (es)
CA (1) CA2262692C (es)
CO (1) CO4900060A1 (es)
CZ (1) CZ292806B6 (es)
DE (1) DE69719193T2 (es)
DK (1) DK0920429T3 (es)
DZ (1) DZ2289A1 (es)
EA (1) EA003188B1 (es)
ES (1) ES2191183T3 (es)
GT (1) GT199700089A (es)
HR (1) HRP970432B1 (es)
ID (1) ID17980A (es)
IL (1) IL128188A0 (es)
IS (1) IS4948A (es)
MA (1) MA24296A1 (es)
NO (1) NO313293B1 (es)
NZ (1) NZ333727A (es)
OA (1) OA10970A (es)
PA (1) PA8435201A1 (es)
PE (1) PE97098A1 (es)
PL (1) PL331602A1 (es)
SA (1) SA97180334A (es)
SK (1) SK14099A3 (es)
TN (1) TNSN97135A1 (es)
TR (1) TR199900228T2 (es)
TW (1) TW550265B (es)
UY (1) UY24655A1 (es)
WO (1) WO1998005661A1 (es)
YU (1) YU5399A (es)
ZA (1) ZA976954B (es)

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Also Published As

Publication number Publication date
BR9710808A (pt) 1999-08-17
TW550265B (en) 2003-09-01
CZ41199A3 (cs) 2000-01-12
NO990544L (no) 1999-03-31
HRP970432A2 (en) 1998-08-31
SA97180334A (ar) 2005-12-03
AP1096A (en) 2002-08-26
HK1021734A1 (en) 2000-06-30
PL331602A1 (en) 1999-08-02
IS4948A (is) 1999-01-19
UY24655A1 (es) 2000-09-29
NO313293B1 (no) 2002-09-09
AU3356397A (en) 1998-02-25
EP0920429B1 (en) 2003-02-19
ATE232863T1 (de) 2003-03-15
SK14099A3 (en) 2000-05-16
CN1093130C (zh) 2002-10-23
MA24296A1 (fr) 1998-04-01
DE69719193T2 (de) 2003-09-25
US6492520B1 (en) 2002-12-10
CN1227552A (zh) 1999-09-01
CZ292806B6 (cs) 2003-12-17
KR20000029843A (ko) 2000-05-25
HRP970432B1 (en) 2002-10-31
CO4900060A1 (es) 2000-03-27
JP3345021B2 (ja) 2002-11-18
JP2000501116A (ja) 2000-02-02
TNSN97135A1 (fr) 2005-03-15
TR199900228T2 (xx) 1999-03-22
AP9701052A0 (en) 1997-10-31
CA2262692C (en) 2002-06-11
GT199700089A (es) 1999-01-26
WO1998005661A1 (en) 1998-02-12
AU709203B2 (en) 1999-08-26
IL128188A0 (en) 1999-11-30
EA003188B1 (ru) 2003-02-27
YU5399A (sh) 2002-03-18
PA8435201A1 (es) 1999-12-27
DE69719193D1 (de) 2003-03-27
DZ2289A1 (fr) 2002-12-25
PE97098A1 (es) 1999-01-12
NZ333727A (en) 2000-09-29
CA2262692A1 (en) 1998-02-12
NO990544D0 (no) 1999-02-05
EP0920429A1 (en) 1999-06-09
DK0920429T3 (da) 2003-05-12
OA10970A (en) 2001-11-05
AR008829A1 (es) 2000-02-23
EA199900083A1 (ru) 1999-08-26
BG103143A (en) 1999-09-30
ID17980A (id) 1998-02-12
ZA976954B (en) 1999-02-05

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