NO890823L - 1h-imidazo-(4,5-c)-kinolin-4-klorforbindelser. - Google Patents

1h-imidazo-(4,5-c)-kinolin-4-klorforbindelser.

Info

Publication number: NO890823L
Authority: NO; Norway
Prior art keywords: carbon atoms; imidazo; quinoline; group; chlorine compounds
Prior art date: 1983-11-18

Application number

NO890823A

Other languages

English (en)

Other versions

NO890823D0 (no

NO165146B (no

NO165146C (no

Inventor

John Franklin Gerster

Original Assignee

Riker Laboratories Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-11-18

Filing date

1989-02-27

Publication date

1985-05-20

1985-05-20 Publication of NO890823L publication Critical patent/NO890823L/no

1989-02-27 Application filed by Riker Laboratories Inc filed Critical Riker Laboratories Inc

1989-02-27 Priority to NO890823A priority Critical patent/NO165146C/no

1989-02-27 Publication of NO890823D0 publication Critical patent/NO890823D0/no

1990-09-24 Publication of NO165146B publication Critical patent/NO165146B/no

1991-01-02 Publication of NO165146C publication Critical patent/NO165146C/no

Links

125000004432 carbon atom Chemical group C* 0.000 abstract 5
125000000217 alkyl group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
ITIRVXDSMXFTPW-UHFFFAOYSA-N 1H-imidazo[4,5-c]quinoline Chemical class C1=CC=CC2=C(NC=N3)C3=CN=C21 ITIRVXDSMXFTPW-UHFFFAOYSA-N 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
125000004210 cyclohexylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Physical Water Treatments (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Macromonomer-Based Addition Polymer (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Alarm Systems (AREA)
Quinoline Compounds (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Luminescent Compositions (AREA)
Lubricants (AREA)

NO890823A 1983-11-18 1989-02-27 1h-imidazo-(4,5-c)-kinolin-4-klorforbindelser. NO165146C (no)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
NO890823A NO165146C (no)	1983-11-18	1989-02-27	1h-imidazo-(4,5-c)-kinolin-4-klorforbindelser.

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US55315883A	1983-11-18	1983-11-18
US55315783A	1983-11-18	1983-11-18
NO844565A NO163819C (no)	1983-11-18	1984-11-15	Analogifremgangsmaate for fremstilling av terapeutisk aktive 1h-imidazo(4,5-c)kinolin og derivater derav.
NO890823A NO165146C (no)	1983-11-18	1989-02-27	1h-imidazo-(4,5-c)-kinolin-4-klorforbindelser.

Publications (4)

Publication Number	Publication Date
NO890823L true NO890823L (no)	1985-05-20
NO890823D0 NO890823D0 (no)	1989-02-27
NO165146B NO165146B (no)	1990-09-24
NO165146C NO165146C (no)	1991-01-02

Family

ID=27070262

Family Applications (7)

Application Number	Title	Priority Date	Filing Date
NO844565A NO163819C (no)	1983-11-18	1984-11-15	Analogifremgangsmaate for fremstilling av terapeutisk aktive 1h-imidazo(4,5-c)kinolin og derivater derav.
NO890822A NO165145C (no)	1983-11-18	1989-02-27	Analogifremgangsmaate for fremstilling av terapeutisk aktive 1h-imidazo-(4,5-c)-kinolin-4-aminderivater.
NO890826A NO168705C (no)	1983-11-18	1989-02-27	3-nitro-kinoliner.
NO890823A NO165146C (no)	1983-11-18	1989-02-27	1h-imidazo-(4,5-c)-kinolin-4-klorforbindelser.
NO890824A NO165147C (no)	1983-11-18	1989-02-27	1h-imidazo(4,5-c)-kinolin-5-oxydforbindelser.
NO890825A NO169437C (no)	1983-11-18	1989-02-27	3-amino-kinoliner.
NO1999015C NO1999015I1 (no)	1983-11-18	1999-07-08	Imiquimod

Family Applications Before (3)

Application Number	Title	Priority Date	Filing Date
NO844565A NO163819C (no)	1983-11-18	1984-11-15	Analogifremgangsmaate for fremstilling av terapeutisk aktive 1h-imidazo(4,5-c)kinolin og derivater derav.
NO890822A NO165145C (no)	1983-11-18	1989-02-27	Analogifremgangsmaate for fremstilling av terapeutisk aktive 1h-imidazo-(4,5-c)-kinolin-4-aminderivater.
NO890826A NO168705C (no)	1983-11-18	1989-02-27	3-nitro-kinoliner.

Family Applications After (3)

Application Number	Title	Priority Date	Filing Date
NO890824A NO165147C (no)	1983-11-18	1989-02-27	1h-imidazo(4,5-c)-kinolin-5-oxydforbindelser.
NO890825A NO169437C (no)	1983-11-18	1989-02-27	3-amino-kinoliner.
NO1999015C NO1999015I1 (no)	1983-11-18	1999-07-08	Imiquimod

Country Status (15)

Country	Link
EP (2)	EP0310950B1 (no)
JP (1)	JPS60123488A (no)
KR (1)	KR900005657B1 (no)
AT (2)	ATE84525T1 (no)
AU (2)	AU581190B2 (no)
CA (1)	CA1271477A (no)
DE (3)	DE3486043T2 (no)
DK (6)	DK164280C (no)
ES (1)	ES537677A0 (no)
IE (1)	IE57874B1 (no)
IL (2)	IL84537A (no)
NL (2)	NL980041I2 (no)
NO (7)	NO163819C (no)
NZ (1)	NZ210228A (no)
PH (1)	PH22338A (no)

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US4929624A (en) *	1989-03-23	1990-05-29	Minnesota Mining And Manufacturing Company	Olefinic 1H-imidazo(4,5-c)quinolin-4-amines
JP2988692B2 (ja) *	1989-07-18	1999-12-13	協和醗酵工業株式会社	イミダゾキノロン誘導体
US4988815A (en) *	1989-10-26	1991-01-29	Riker Laboratories, Inc.	3-Amino or 3-nitro quinoline compounds which are intermediates in preparing 1H-imidazo[4,5-c]quinolines
FR2654021B1 (fr) *	1989-11-07	1992-02-28	Simond Jacques	Procede de vitrification de cendres volantes et dispositif pour sa mise en óoeuvre.
GB8928281D0 (en) *	1989-12-14	1990-02-21	Smith Kline French Lab	Compounds
ATE143661T1 (de) *	1990-06-01	1996-10-15	Kyowa Hakko Kogyo Kk	Imidazonaphthyridinderivate
CA2289219C (en) *	1991-03-01	2003-05-20	Minnesota Mining And Manufacturing Company	1-substituted, 2-substituted 1h-imidazo[4,5-c]quinolin-4-amines
US5266575A (en) *	1991-11-06	1993-11-30	Minnesota Mining And Manufacturing Company	2-ethyl 1H-imidazo[4,5-ciquinolin-4-amines
IL105325A (en) *	1992-04-16	1996-11-14	Minnesota Mining & Mfg	Immunogen/vaccine adjuvant composition
US5395937A (en) *	1993-01-29	1995-03-07	Minnesota Mining And Manufacturing Company	Process for preparing quinoline amines
US5693811A (en) *	1996-06-21	1997-12-02	Minnesota Mining And Manufacturing Company	Process for preparing tetrahdroimidazoquinolinamines
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JPH10298181A (ja) *	1997-04-25	1998-11-10	Sumitomo Pharmaceut Co Ltd	タイプ２ヘルパーｔ細胞選択的免疫応答抑制剤
JP2000119271A (ja)	1998-08-12	2000-04-25	Hokuriku Seiyaku Co Ltd	１ｈ―イミダゾピリジン誘導体
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PT1543002E (pt)	2002-07-23	2006-11-30	Teva Gyogyszergyar Zartkoeruen	Preparação de intermediários 1h-imidazo ( 4,5-c )quinolin-4-aminas via 1h- imidazo (4,5-c ) quinolina-4-ftalimida
PL374866A1 (en)	2002-07-26	2005-11-14	Teva Gyogyszergyar Zartköruen Muködo Reszvenytarsasag	Preparation of 1h-imidazo [4,5-c] quinolin-4-amines via novel 1h-imidazo [4,5-c] quinolin-4-cyano and 1h-imidazo [4,5-c] quinolin-4-carboxamide intermediates
BRPI0413558A (pt)	2003-08-12	2006-10-17	3M Innovative Properties Co	compostos contendo imidazo substituìdo por hidroxilamina
MXPA06002199A (es) *	2003-08-27	2006-05-22	3M Innovative Properties Co	Imidazoquinolinas sustituidas con grupos ariloxi o arilalquilenoxi.
CA2537763A1 (en)	2003-09-05	2005-03-17	3M Innovative Properties Company	Treatment for cd5+ b cell lymphoma
CA2536530A1 (en)	2003-10-01	2005-04-14	Taro Pharmaceuticals U.S.A., Inc.	Method of preparing 4-amino-1h-imidazo(4,5-c)quinolines and acid addition salts thereof
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ES2577514T3 (es)	2005-08-22	2016-07-15	The Regents Of The University Of California	Antagonistas de TLR
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US7906506B2 (en)	2006-07-12	2011-03-15	3M Innovative Properties Company	Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods
ES2552471T3 (es)	2007-02-07	2015-11-30	The Regents Of The University Of California	Conjugados de agonistas de TLR sintéticos y usos de los mismos
EP2009002A1 (en) *	2007-06-21	2008-12-31	Institut National De La Sante Et De La Recherche Medicale (Inserm)	New process for the manufacture of 1H-imidazo [4,5-c]-quinoline ring systems
WO2010088924A1 (en)	2009-02-06	2010-08-12	Telormedix Sa	Pharmaceutical compositions comprising imidazoquinolin(amines) and derivatives thereof suitable for local administration
KR20110117705A (ko)	2009-02-11	2011-10-27	더 리전트 오브 더 유니버시티 오브 캘리포니아	톨-유사 수용체 조정제 및 질병의 치료
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US8728486B2 (en)	2011-05-18	2014-05-20	University Of Kansas	Toll-like receptor-7 and -8 modulatory 1H imidazoquinoline derived compounds
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US3700674A (en) *	1969-04-30	1972-10-24	American Cyanamid Co	4-alkylamino-3-nitroquinolines
IL68495A0 (en) *	1982-05-03	1983-07-31	Lilly Co Eli	2-phenylimidazo(4,5-c)pyridines

1984
- 1984-11-13 CA CA000467706A patent/CA1271477A/en not_active Expired - Lifetime
- 1984-11-14 AU AU35402/84A patent/AU581190B2/en not_active Expired
- 1984-11-15 DK DK542684A patent/DK164280C/da not_active IP Right Cessation
- 1984-11-15 ES ES537677A patent/ES537677A0/es active Granted
- 1984-11-15 NO NO844565A patent/NO163819C/no not_active IP Right Cessation
- 1984-11-16 PH PH31451A patent/PH22338A/en unknown
- 1984-11-16 AT AT88116137T patent/ATE84525T1/de not_active IP Right Cessation
- 1984-11-16 IL IL84537A patent/IL84537A/xx not_active IP Right Cessation
- 1984-11-16 DE DE8888116137T patent/DE3486043T2/de not_active Expired - Lifetime
- 1984-11-16 DE DE1999175027 patent/DE19975027I2/de active Active
- 1984-11-16 NZ NZ210228A patent/NZ210228A/xx unknown
- 1984-11-16 AT AT84307974T patent/ATE49763T1/de active
- 1984-11-16 IE IE2952/84A patent/IE57874B1/en not_active IP Right Cessation
- 1984-11-16 EP EP88116137A patent/EP0310950B1/en not_active Expired - Lifetime
- 1984-11-16 DE DE8484307974T patent/DE3481124D1/de not_active Expired - Lifetime
- 1984-11-16 EP EP84307974A patent/EP0145340B1/en not_active Expired - Lifetime
- 1984-11-17 JP JP59243142A patent/JPS60123488A/ja active Granted
- 1984-11-17 KR KR1019840007224A patent/KR900005657B1/ko not_active Expired
1987
- 1987-11-19 IL IL84537A patent/IL84537A0/xx unknown
1989
- 1989-02-14 AU AU29911/89A patent/AU611997B2/en not_active Expired
- 1989-02-27 NO NO890822A patent/NO165145C/no not_active IP Right Cessation
- 1989-02-27 NO NO890826A patent/NO168705C/no not_active IP Right Cessation
- 1989-02-27 NO NO890823A patent/NO165146C/no not_active IP Right Cessation
- 1989-02-27 NO NO890824A patent/NO165147C/no not_active IP Right Cessation
- 1989-02-27 NO NO890825A patent/NO169437C/no not_active IP Right Cessation
1991
- 1991-07-16 DK DK135791A patent/DK169179B1/da not_active IP Right Cessation
- 1991-07-16 DK DK136091A patent/DK164451C/da not_active IP Right Cessation
- 1991-07-16 DK DK135891A patent/DK164455C/da not_active IP Right Cessation
- 1991-07-16 DK DK136191A patent/DK164452C/da not_active IP Right Cessation
- 1991-07-16 DK DK135991A patent/DK165921C/da not_active IP Right Cessation
1998
- 1998-12-14 NL NL980041C patent/NL980041I2/nl unknown
- 1998-12-14 NL NL980043C patent/NL980043I1/nl unknown
1999
- 1999-07-08 NO NO1999015C patent/NO1999015I1/no unknown

Also Published As

Publication number	Publication date
DK135891A (da)	1991-07-16
ES8603477A1 (es)	1985-12-16
ATE49763T1 (de)	1990-02-15
DE19975027I2 (de)	2000-09-21
NL980041I2 (nl)	1999-07-01
NO890825L (no)	1985-05-20
NO163819C (no)	1990-08-01
NO168705B (no)	1991-12-16
DK542684A (da)	1985-05-19
NO169437B (no)	1992-03-16
NO844565L (no)	1985-05-20
NO890822D0 (no)	1989-02-27
NO890823D0 (no)	1989-02-27
IL84537A (en)	1990-12-23
NO165145B (no)	1990-09-24
JPS60123488A (ja)	1985-07-02
KR850003890A (ko)	1985-06-29
DK164452C (da)	1992-11-09
DK164280B (da)	1992-06-01
DK164451C (da)	1992-11-09
DK169179B1 (da)	1994-09-05
EP0310950A1 (en)	1989-04-12
ES537677A0 (es)	1985-12-16
IE57874B1 (en)	1993-05-05
DK165921C (da)	1993-06-28
NO890822L (no)	1985-05-20
IL84537A0 (en)	1988-04-29
NO890826D0 (no)	1989-02-27
IE842952L (en)	1985-05-18
DK135791A (da)	1991-07-16
AU3540284A (en)	1985-05-23
DK135791D0 (da)	1991-07-16
NO890824D0 (no)	1989-02-27
EP0310950B1 (en)	1993-01-13
EP0145340A3 (en)	1986-06-11
NO165146B (no)	1990-09-24
NO1999015I1 (no)	1999-07-08
EP0145340A2 (en)	1985-06-19
DE3486043D1 (de)	1993-02-25
ATE84525T1 (de)	1993-01-15
AU581190B2 (en)	1989-02-16
EP0145340B1 (en)	1990-01-24
NO165147B (no)	1990-09-24
DK135991D0 (da)	1991-07-16
KR900005657B1 (ko)	1990-08-03
AU611997B2 (en)	1991-06-27
DK164455B (da)	1992-06-29
DK135991A (da)	1991-07-16
NO165146C (no)	1991-01-02
DK136191D0 (da)	1991-07-16
AU2991189A (en)	1989-06-15
DK164452B (da)	1992-06-29
NZ210228A (en)	1989-01-27
NO890825D0 (no)	1989-02-27
CA1271477A (en)	1990-07-10
NO163819B (no)	1990-04-17
NL980043I1 (nl)	1999-02-01
NO165147C (no)	1991-01-02
DE3486043T2 (de)	1993-06-03
DK135891D0 (da)	1991-07-16
DK164280C (da)	1992-11-30
DE3481124D1 (de)	1990-03-01
NO169437C (no)	1992-06-24
JPH0586391B2 (no)	1993-12-10
DK165921B (da)	1993-02-08
NO165145C (no)	1991-01-02
NO890826L (no)	1985-05-20
PH22338A (en)	1988-08-12
NL980041I1 (nl)	1999-02-01
DK542684D0 (da)	1984-11-15
DK136091D0 (da)	1991-07-16
NO890824L (no)	1985-05-20
DK136091A (da)	1991-07-16
DK164455C (da)	1992-11-16
DK164451B (da)	1992-06-29
DK136191A (da)	1991-07-16
NO168705C (no)	1992-03-25

Legal Events

Date	Code	Title	Description
2004-12-13	MM1K	Lapsed by not paying the annual fees