FI104465B - Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö - Google Patents

Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö Download PDF

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Publication number
FI104465B
FI104465B FI952926A FI952926A FI104465B FI 104465 B FI104465 B FI 104465B FI 952926 A FI952926 A FI 952926A FI 952926 A FI952926 A FI 952926A FI 104465 B FI104465 B FI 104465B
Authority
FI
Finland
Prior art keywords
preparation
lactobacillus
atcc
protein hydrolyzate
treatment
Prior art date
Application number
FI952926A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI952926L (fi
FI952926A0 (fi
Inventor
Eeva-Liisa Syvaeoja
Hannu Korhonen
Erika Isolauri
Leena Metsaeniitty
Seppo Salminen
Original Assignee
Valio Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8543602&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI104465(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Valio Oy filed Critical Valio Oy
Priority to FI952926A priority Critical patent/FI104465B/fi
Publication of FI952926A0 publication Critical patent/FI952926A0/fi
Priority to MYPI96002357A priority patent/MY113912A/en
Priority to EP96918707A priority patent/EP0833649B2/en
Priority to US08/973,963 priority patent/US6506380B1/en
Priority to RO97-02328A priority patent/RO120243B1/ro
Priority to CZ19973997A priority patent/CZ291904B6/cs
Priority to KR1019970709383A priority patent/KR100494741B1/ko
Priority to SK1715-97A priority patent/SK284245B6/sk
Priority to PCT/FI1996/000350 priority patent/WO1997000078A1/en
Priority to ES96918707T priority patent/ES2191103T5/es
Priority to HK98110938.7A priority patent/HK1010081B/en
Priority to DK96918707T priority patent/DK0833649T4/da
Priority to BR9607827-8A priority patent/BR9607827A/pt
Priority to PL96324010A priority patent/PL185123B1/pl
Priority to CA2224320A priority patent/CA2224320C/en
Priority to EE9700339A priority patent/EE03424B1/xx
Priority to AT96918707T priority patent/ATE230606T1/de
Priority to JP50267197A priority patent/JP3983804B2/ja
Priority to NZ310478A priority patent/NZ310478A/xx
Priority to DE69625690T priority patent/DE69625690T3/de
Priority to CNB961947527A priority patent/CN1154506C/zh
Priority to IL12257796A priority patent/IL122577A0/xx
Priority to AU61278/96A priority patent/AU710126C/en
Priority to ARP960103134A priority patent/AR003960A1/es
Priority to ZA965088A priority patent/ZA965088B/xx
Publication of FI952926L publication Critical patent/FI952926L/fi
Priority to MX9710109A priority patent/MX9710109A/es
Priority to NO19975832A priority patent/NO321504B1/no
Priority to BG102144A priority patent/BG63153B1/bg
Publication of FI104465B publication Critical patent/FI104465B/fi
Application granted granted Critical
Priority to US10/321,661 priority patent/US7172756B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/018—Hydrolysed proteins; Derivatives thereof from animals from milk
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A23J3/341—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
    • A23J3/343—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins
    • A23J3/344—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins of casein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Dairy Products (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI952926A 1995-06-14 1995-06-14 Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö FI104465B (fi)

Priority Applications (29)

Application Number Priority Date Filing Date Title
FI952926A FI104465B (fi) 1995-06-14 1995-06-14 Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö
MYPI96002357A MY113912A (en) 1995-06-14 1996-06-11 Method of preventing or treating allergies
AU61278/96A AU710126C (en) 1995-06-14 1996-06-12 Methods of preventing or treating allergies
PL96324010A PL185123B1 (pl) 1995-06-14 1996-06-12 Sposób wytwarzania mieszanki hydrolizatu białkowego i zastosowanie mieszanki hydrolizatu białkowego
JP50267197A JP3983804B2 (ja) 1995-06-14 1996-06-12 アレルギーを予防または治療する方法
RO97-02328A RO120243B1 (ro) 1995-06-14 1996-06-12 Procedee de preparare a unor formule de hidrolizat proteic, pentru prevenirea sau tratarea alergiilor şi utilizarea acestora
CZ19973997A CZ291904B6 (cs) 1995-06-14 1996-06-12 Způsob výroby proteinového hydrolyzátového prostředku, tento prostředek a jeho použití
KR1019970709383A KR100494741B1 (ko) 1995-06-14 1996-06-12 알레르기의치료또는예방방법
SK1715-97A SK284245B6 (sk) 1995-06-14 1996-06-12 Spôsob výroby proteínového hydrolyzátového prostriedku a jeho použitie
PCT/FI1996/000350 WO1997000078A1 (en) 1995-06-14 1996-06-12 Methods of preventing or treating allergies
ES96918707T ES2191103T5 (es) 1995-06-14 1996-06-12 Procedimientos de prevencion o de tratamiento de alergia.
HK98110938.7A HK1010081B (en) 1995-06-14 1996-06-12 Methods of preventing or treating allergies
DK96918707T DK0833649T4 (da) 1995-06-14 1996-06-12 Proteinhydrolysatpræparater til forebyggelse eller behandling af allergier
BR9607827-8A BR9607827A (pt) 1995-06-14 1996-06-12 Método para fazer uma fórmula de hidrolisado de proteìna, fórmula de hidrolizado de proteìna,métodos de prevenir ou tratar reações de hipersensibilidade induzidas por alimentos, de tratar alergia a leite de vaca e de promoves respostas tolerogênicas imunes a antìgenos de alimentos.
EP96918707A EP0833649B2 (en) 1995-06-14 1996-06-12 Methods of preventing or treating allergies
CA2224320A CA2224320C (en) 1995-06-14 1996-06-12 Method of promoting hypoallergenicity or tolerogenic immune response and compositions therefor
EE9700339A EE03424B1 (et) 1995-06-14 1996-06-12 Allergiavastase valguhüdrolüsaadipreparaadi valmistamise meetod
AT96918707T ATE230606T1 (de) 1995-06-14 1996-06-12 Verfahren zur vorbeugung und behandlung von allergien
US08/973,963 US6506380B1 (en) 1995-06-14 1996-06-12 Methods of preventing or treating allergies
NZ310478A NZ310478A (en) 1995-06-14 1996-06-12 method of making a protein hydrolysate formulation derived by hydrolysing proteins with enzymes from a probiotic gastointestinal bacteria and with pepsin and/or trypsin
DE69625690T DE69625690T3 (de) 1995-06-14 1996-06-12 Verfahren zur vorbeugung und behandlung von allergien
CNB961947527A CN1154506C (zh) 1995-06-14 1996-06-12 预防或治疗过敏的方法
IL12257796A IL122577A0 (en) 1995-06-14 1996-06-12 Methods of preventing or treating allergies
ARP960103134A AR003960A1 (es) 1995-06-14 1996-06-13 Metodo y medios para suprimir reacciones de hipersensibilidad inducidas por alimentos en pacientes que sufren de alergia a los alimentos
ZA965088A ZA965088B (en) 1995-06-14 1996-06-14 Methods of preventing or treating allergles
MX9710109A MX9710109A (es) 1995-06-14 1997-12-11 Metodo y medios para suprimir reacciones de hipersensibilidad inducidas por alimentos en pacientes que sufren de alergia a los alimentos.
NO19975832A NO321504B1 (no) 1995-06-14 1997-12-11 Fremgangsmater for in vitro fremstilling av proteinhydrolysatsammensetning, oral proteinhydrolysatsammensetning og anvendelser derav.
BG102144A BG63153B1 (bg) 1995-06-14 1997-12-23 Метод за получаване на протеинов хидролизат и използването му за предотвратяване или лечение на алергии
US10/321,661 US7172756B2 (en) 1995-06-14 2002-12-18 Methods of promoting tolerogenic immune responses and compositions therefor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI952926 1995-06-14
FI952926A FI104465B (fi) 1995-06-14 1995-06-14 Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö

Publications (3)

Publication Number Publication Date
FI952926A0 FI952926A0 (fi) 1995-06-14
FI952926L FI952926L (fi) 1996-12-15
FI104465B true FI104465B (fi) 2000-02-15

Family

ID=8543602

Family Applications (1)

Application Number Title Priority Date Filing Date
FI952926A FI104465B (fi) 1995-06-14 1995-06-14 Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö

Country Status (26)

Country Link
US (2) US6506380B1 (2)
EP (1) EP0833649B2 (2)
JP (1) JP3983804B2 (2)
KR (1) KR100494741B1 (2)
CN (1) CN1154506C (2)
AR (1) AR003960A1 (2)
AT (1) ATE230606T1 (2)
BG (1) BG63153B1 (2)
BR (1) BR9607827A (2)
CA (1) CA2224320C (2)
CZ (1) CZ291904B6 (2)
DE (1) DE69625690T3 (2)
DK (1) DK0833649T4 (2)
EE (1) EE03424B1 (2)
ES (1) ES2191103T5 (2)
FI (1) FI104465B (2)
IL (1) IL122577A0 (2)
MX (1) MX9710109A (2)
MY (1) MY113912A (2)
NO (1) NO321504B1 (2)
NZ (1) NZ310478A (2)
PL (1) PL185123B1 (2)
RO (1) RO120243B1 (2)
SK (1) SK284245B6 (2)
WO (1) WO1997000078A1 (2)
ZA (1) ZA965088B (2)

Families Citing this family (171)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI104465B (fi) * 1995-06-14 2000-02-15 Valio Oy Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö
JP2002502430A (ja) * 1997-06-03 2002-01-22 ガネデン バイオテック，インコーポレイテッド Ｓｉｄｓに関連する細菌感染を処置するための共生乳酸細菌
ES2341217T3 (es) 1999-01-19 2010-06-17 Maxygen, Inc. Recombinacion de acidos nucleicos mediada por oligonucleotidos.
ES2296635T3 (es) 1999-08-05 2008-05-01 Societe Des Produits Nestle S.A. Bifidobacteria capaz de prevenir la diarrea.
ES2321797T3 (es) 1999-08-05 2009-06-12 Societe Des Produits Nestle S.A. Bifidobacterias que previenen la diarrea causada por bacterias patogenicas.
WO2001057534A2 (en) * 2000-02-04 2001-08-09 Bioseek Compositions and methods for reducing autoimmunity
FI110668B (fi) * 2000-06-20 2003-03-14 Aboatech Ab Oy Probioottien käyttö atooppisten sairauksien primaariseen ehkäisyyn
IL154284A0 (en) * 2000-09-25 2003-09-17 Nestle Sa Lactic acid bacteria capable of reducing an individual's tendency to develop allergic reactions
BRPI0114400B8 (pt) 2000-10-06 2021-05-25 Nestle Sa uso de bactéria de ácido lático probiótica para equilibrar o sistema imunológico da pele
FI109602B (fi) * 2001-01-25 2002-09-13 Valio Oy Probioottiyhdistelmä
EP1228707A1 (en) * 2001-02-01 2002-08-07 Campina Melkunie B.V. Use of alpha-lactalbumin as prebiotic agent
EA006429B1 (ru) * 2001-03-09 2005-12-29 Сосьете Де Продюи Нестле С.А. Композиция для предупреждения или восстановления возрастных функциональных дефицитов у млекопитающих и способ ее применения
JP2003137804A (ja) * 2001-10-31 2003-05-14 Morinaga Milk Ind Co Ltd インターロイキン−１８誘導剤
EP1364586A1 (en) * 2002-05-24 2003-11-26 Nestec S.A. Probiotics and oral tolerance
ES2540926T3 (es) 2002-06-04 2015-07-14 Dsm Ip Assets B.V. Hidrolizado de proteínas rico en tripéptidos
DK1565547T4 (da) 2002-06-28 2013-01-14 Biosearch S A Probiotiske stammer, en fremgangsmåde til selektion deraf, præparater deraf samt anvendelse deraf
EP1384483A1 (en) * 2002-07-23 2004-01-28 Nestec S.A. Probiotics for treatment of irritable bowel disease (IBS) through improvement of gut neuromuscular function
US7105336B2 (en) * 2002-10-07 2006-09-12 Biogaia Ab Selection and use of lactic acid bacteria for reducing inflammation caused by Helicobacter
US20040208863A1 (en) * 2003-01-30 2004-10-21 James Versalovic Anti-inflammatory activity from lactic acid bacteria
CN1863463B (zh) 2003-06-23 2011-05-04 雀巢技术公司 用于促进肠道屏障成熟的营养组合物
KR101225918B1 (ko) 2004-02-25 2013-01-24 파이어니어 하이 부렛드 인터내쇼날 인코포레이팃드 신규한 바실루스 투링기엔시스 결정 폴리펩티드,폴리뉴클레오티드, 및 이의 조성물
US20050265946A1 (en) * 2004-05-28 2005-12-01 Kao Corporation Elastase inhibitor
US7862808B2 (en) * 2004-07-01 2011-01-04 Mead Johnson Nutrition Company Method for preventing or treating respiratory infections and acute otitis media in infants using Lactobacillus rhamnosus LGG and Bifidobacterium lactis Bb-12
AU2006233918B2 (en) 2005-04-13 2012-06-21 Nestec S.A. Infant formula with probiotics
US20060233762A1 (en) * 2005-04-15 2006-10-19 Mcmahon Robert J Method for treating or preventing systemic inflammation in formula-fed infants
US7303745B2 (en) 2005-04-15 2007-12-04 Bristol-Myers Squibb Company Method for preventing or treating the development of respiratory allergies
WO2007054587A1 (en) * 2005-11-14 2007-05-18 Nestec S.A. Oral tolerance promotion with glycated proteins
ES2381211T3 (es) 2006-02-15 2012-05-24 Nestec S.A. Uso del Bifidobacterium longum para prevenir y tratar inflamaciones
RU2448720C2 (ru) 2006-03-07 2012-04-27 Нестек С.А. Синбиотическая смесь
CN101460067B (zh) * 2006-06-15 2012-09-26 雀巢产品技术援助有限公司 诱导对卵蛋白的耐受
CN105796607A (zh) * 2007-02-28 2016-07-27 Mjn 美国控股有限责任公司 用于儿童或婴幼儿的含有灭活益生菌的产品
EP1974743A1 (en) 2007-03-28 2008-10-01 Nestec S.A. Probiotics to Improve Gut Microbiota
EP1974735A1 (en) 2007-03-28 2008-10-01 Nestec S.A. Reduction of risk of diarrhoea
EP1974734A1 (en) † 2007-03-28 2008-10-01 Nestec S.A. Probiotics for reduction of risk of obesity
CN101273737B (zh) * 2007-03-28 2011-08-24 哈尔滨正方科技有限公司 一种在常温下保持高活菌数的发酵乳饮料的制备方法
JP2010536385A (ja) 2007-08-24 2010-12-02 コデクシス， インコーポレイテッド （ｒ）−３−ヒドロキシチオランの立体選択的生成のための改善されたケトレダクターゼポリペプチド
EP2072052A1 (en) 2007-12-17 2009-06-24 Nestec S.A. Prevention of opportunistic infections in immune-compromised subjects
KR20100120169A (ko) 2008-01-24 2010-11-12 네스텍 소시에테아노님 영양 성분을 담고 있는 캡슐 및 이 캡슐로부터 영양액을 전달하는 방법
PL2244734T3 (pl) 2008-02-01 2017-01-31 Murdoch Childrens Research Institute Sposób indukcji tolerancji na alergen
ES2658837T3 (es) 2008-03-14 2018-03-12 Nestec S.A. Mezcla simbiótica
EP2127661A1 (en) 2008-05-27 2009-12-02 Nestec S.A. Probiotics to improve gut microbiotica
DK3023494T3 (en) 2008-06-13 2019-02-25 Codexis Inc PROCEDURE FOR SYNTHESIS OF POLYNUCLEOTIDE VARIETIES
US20090312196A1 (en) 2008-06-13 2009-12-17 Codexis, Inc. Method of synthesizing polynucleotide variants
MX2010014500A (es) 2008-06-24 2011-05-30 Codexis Inc Procedimientos biocataliticos para la preparacion de compuestos de prolina biciclica fusionada sustancialmente estereomericamente puros.
EP2147678A1 (en) 2008-07-21 2010-01-27 Nestec S.A. Probiotics to increase IgA secretion in infants born by caesarean section
RU2392001C2 (ru) * 2008-08-04 2010-06-20 Государственное образовательное учреждение высшего профессионального образования "Нижегородская государственная медицинская академия Федерального агентства по здравоохранению и социальному развитию" Способ лечения желтушных форм вирусного гепатита а у детей с пищевой аллергией
EP2329013B1 (en) 2008-08-27 2015-10-28 Codexis, Inc. Ketoreductase polypeptides for the production of a 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine
HUE052297T2 (hu) 2009-01-08 2021-04-28 Codexis Inc Transzamináz polipeptidek
BRPI1013886A2 (pt) 2009-03-17 2016-10-11 Codexis Inc variantes de endoglucanases, polinucleotídeos e usos a elas relacionados
CA2757040C (en) 2009-03-31 2016-02-09 Codexis, Inc. Improved endoglucanases
BRPI1012922A2 (pt) 2009-06-16 2016-10-11 Codexis Inc polipeptídeo de b-glicosidase variante, vetor de expressão, célula hospedeira, método de produção de polipeptídeo de b-glicosidase variante, composição enzimática, método de conversão de um substrato de biomassa em açucar fermentável e método de produção de álcool
SG177331A1 (en) 2009-06-22 2012-02-28 Codexis Inc Ketoreductase-mediated stereoselective route to alpha chloroalcohols
US8614081B2 (en) 2009-07-23 2013-12-24 Codexis, Inc. Nitrilase biocatalysts
CN102905557A (zh) 2009-08-18 2013-01-30 雀巢产品技术援助有限公司 包含长双歧杆菌菌株并且特别是在婴儿和儿童中减少食物过敏症状的营养组合物
CN102695427B (zh) 2009-08-18 2016-04-13 雀巢产品技术援助有限公司 包含乳球菌属菌株并且特别是在婴儿和儿童中减少过敏症状的营养组合物
ES2575560T3 (es) 2009-08-19 2016-06-29 Codexis, Inc. Polipéptidos cetorreductasa para preparar fenilefrina
WO2011028708A1 (en) 2009-09-04 2011-03-10 Codexis, Inc. Variant cbh2 cellulases and related polynucleotides
EP2295535A1 (en) * 2009-09-11 2011-03-16 Mead Johnson Nutrition Company Probiotic material
DK3301208T3 (da) 2009-09-18 2020-12-14 Codexis Inc Reduceret codon-mutagenese
MX2012006016A (es) 2009-11-25 2012-06-25 Codexis Inc Variantes de beta-glucosidasa recombinante para produccion de azucares solubles de biomasa celulosica.
BR112012012192A2 (pt) 2009-11-25 2017-07-04 Codexis Inc b-glicosidades variantes recombinantes thermoascus aurantiacus para produção de açúcares fermentáveis a partir da biomassa celulósica
EP2509429A1 (en) 2009-12-08 2012-10-17 Nestec S.A. Infant formula with probiotics and milk fat globule membrane components
CN102884178B (zh) 2009-12-08 2014-12-03 科德克希思公司 拉唑化合物的合成
MX2012007681A (es) 2009-12-31 2013-01-29 Pioneer Hi Bred Int Ingenieria de resistencia de plantas a enfermedades causadas por patogenos.
HUE026367T2 (en) 2010-05-04 2016-06-28 Codexis Inc Biocatalysts for ezetimibe synthesis
WO2011143274A1 (en) 2010-05-10 2011-11-17 Perseid Therapeutics Polypeptide inhibitors of vla4
WO2011150313A1 (en) 2010-05-28 2011-12-01 Codexis, Inc. Pentose fermentation by a recombinant microorganism
HUE038434T2 (hu) 2010-06-17 2018-10-29 Codexis Inc Biokatalizátorok és módszerek (S)-3(1-aminoetil)-fenol szintéziséhez
US8574878B2 (en) 2010-06-28 2013-11-05 Behnaz Behrouzian Fatty alcohol forming acyl reductases (FARs) and methods of use thereof
CA2803952C (en) 2010-06-30 2020-03-24 Codexis, Inc. Highly stable beta-class carbonic anhydrases useful in carbon capture systems
US9006460B2 (en) 2010-08-16 2015-04-14 Cardiome International Ag Process for preparing aminocyclohexyl ether compounds
CA2807702C (en) 2010-08-20 2018-07-24 Codexis, Inc. Use of glycoside hydrolase 61 family proteins in processing of cellulose
EP2649187B1 (en) 2010-12-08 2017-11-22 Codexis, Inc. Biocatalysts and methods for the synthesis of armodafinil
EE05750B1 (et) 2011-02-25 2015-06-15 OÜ Tervisliku Piima Biotehnoloogiate Arenduskeskus Isoleeritud mikroorganismi tüvi Lactobacillus gasseri MCC2 DSM 23882 ning selle kasutamine
US8663962B2 (en) 2011-03-30 2014-03-04 Codexis, Inc. Pentose fermentation by a recombinant microorganism
HUE038800T2 (hu) 2011-04-13 2018-11-28 Codexis Inc Biokatalitikus eljárás eszlikarbazepin és ennek analógjai elõállítására
UA111078C2 (uk) * 2011-05-03 2016-03-25 Нестек С.А. Гідролізат білкового субстрату і спосіб його виготовлення
US8778652B2 (en) 2011-06-30 2014-07-15 Codexis, Inc. Pentose fermentation by a recombinant microorganism
EP2748317B1 (en) 2011-08-22 2017-04-19 Codexis, Inc. Gh61 glycoside hydrolase protein variants and cofactors that enhance gh61 activity
WO2013036861A1 (en) 2011-09-08 2013-03-14 Codexis, Inc Biocatalysts and methods for the synthesis of substituted lactams
WO2013048661A1 (en) 2011-09-30 2013-04-04 Codexis, Inc. Fungal proteases
WO2013052101A1 (en) * 2011-10-03 2013-04-11 Kelly Foods Corporation Probiotic composition for pets and method of providing the same
US20130089638A1 (en) * 2011-10-11 2013-04-11 Mead Johnson Nutrition Company Compositions Comprising Maltotriose And Methods Of Using Same To Inhibit Damage Caused By Dehydration Processes
IN2014CN04470A (2) 2011-11-18 2015-09-04 Codexis Inc
BR112014015030A2 (pt) 2011-12-20 2017-06-13 Codexis Inc variantes da endoflucanase 1b (eg1b)
CN104508126B (zh) 2012-03-23 2017-06-30 科德克希思公司 用于合成色胺和色胺类似物的衍生物的生物催化剂和方法
US20130251829A1 (en) * 2012-03-23 2013-09-26 Mead Johnson Nutrition Company Probiotic derived non-viable material for infection prevention and treatment
SG11201407295YA (en) 2012-05-08 2014-12-30 Codexis Inc Biocatalysts and methods for hydroxylation of chemical compounds
HUE036947T2 (hu) 2012-05-11 2018-08-28 Codexis Inc Átalakított iminreduktázok és eljárások keton- és aminvegyületek reduktív aminálására
US8980578B2 (en) 2012-06-11 2015-03-17 Codexis, Inc. Fungal beta-xylosidase variants
EP2922953A4 (en) 2012-11-20 2016-11-09 Shell Int Research PENTOSEFERMENTATION BY A RECOMBINANT MICROORGANISM
US9738915B2 (en) 2012-12-07 2017-08-22 Merck Sharp & Dohme Corp. Biocatalytic transamination process
SG11201504752YA (en) 2012-12-21 2015-07-30 Codexis Inc Engineered biocatalysts and methods for synthesizing chiral amines
EP2946006B1 (en) 2013-01-18 2019-04-10 Codexis, Inc. Engineered biocatalysts useful for carbapenem synthesis
US9617573B2 (en) 2013-02-28 2017-04-11 Codexis, Inc. Engineered transaminase polypeptides for industrial biocatalysis
CN103355405A (zh) * 2013-04-07 2013-10-23 苏州旭优食品科技有限公司 一种低过敏性含乳制品的加工工艺
NZ713396A (en) 2013-04-18 2020-06-26 Codexis Inc Engineered phenylalanine ammonia lyase polypeptides
CN106232619B (zh) 2013-11-13 2022-09-09 科德克希思公司 工程化的亚胺还原酶和用于酮和胺化合物的还原胺化的方法
WO2015161019A1 (en) 2014-04-16 2015-10-22 Codexis, Inc. Engineered tyrosine ammonia lyase
US9708587B2 (en) 2014-07-09 2017-07-18 Codexis, Inc. P450-BM3 variants with improved activity
MA41020A (fr) 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
US10370648B2 (en) 2014-11-25 2019-08-06 Codexis, Inc. Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
LT3237621T (lt) 2014-12-22 2023-09-25 Codexis, Inc. Žmogaus alfa-galaktozidazės variantai
WO2016130412A1 (en) 2015-02-10 2016-08-18 Codexis, Inc. Ketoreductase polypeptides for the synthesis of chiral compounds
CN107531762A (zh) 2015-05-07 2018-01-02 科德克希思公司 青霉素g酰化酶
US9683220B2 (en) 2015-07-07 2017-06-20 Codexis, Inc. P450-BM3 variants with improved activity
US10724025B2 (en) 2016-05-05 2020-07-28 Codexis, Inc. Penicillin-G acylases
WO2017213758A1 (en) 2016-06-09 2017-12-14 Codexis, Inc. Biocatalysts and methods for hydroxylation of chemical compounds
MX2018015534A (es) 2016-06-15 2019-03-14 Codexis Inc Beta-glucosidasas dise?adas y metodos de glucosilacion.
IL264686B2 (en) 2016-08-26 2024-07-01 Codexis Inc Engineered imine reductases and methods for reversible amination of ketone and amine compounds
EP3565893A4 (en) 2017-01-05 2020-12-09 Codexis, Inc. PENICILLIN G ACYLASES
CA3175070A1 (en) 2017-02-03 2018-08-09 Codexis, Inc. Engineered glycosyltransferases and steviol glycoside glucosylation methods
MX2019009615A (es) 2017-02-13 2019-10-14 Codexis Inc Polipeptidos dise?ados de fenilalanina amonio liasa.
MA48475A (fr) 2017-04-24 2020-03-04 Tesaro Inc Procédés de fabrication de niraparib
CN110831618B (zh) 2017-04-27 2023-08-25 科德克希思公司 酮还原酶多肽及多核苷酸
ES2887078T3 (es) 2017-05-08 2021-12-21 Codexis Inc Variantes de ligasa diseñadas
EP3638688A4 (en) 2017-06-14 2021-07-07 Codexis, Inc. MODIFIED TRANSAMINASE POLYPEPTIDES INTENDED FOR INDUSTRIAL BIOCATALYSIS
CN117737045A (zh) 2017-06-27 2024-03-22 科德克希思公司 青霉素g酰化酶
KR20250028535A (ko) 2017-06-30 2025-02-28 코덱시스, 인코포레이티드 T7 rna 폴리머라제 변이체
EP3645712A4 (en) 2017-06-30 2021-07-07 Codexis, Inc. T7 RNA POLYMERASE VARIANTS
EP3706780A4 (en) 2017-11-07 2021-12-22 Codexis, Inc. TRANSGLUTAMINASE VARIANTS
JP2021506252A (ja) 2017-12-13 2021-02-22 コデクシス， インコーポレイテッド アミドカップリングのためのカルボキシエステラーゼポリペプチド
CN111465688A (zh) 2017-12-13 2020-07-28 葛兰素史密斯克莱知识产权发展有限公司 羧酸酯酶催化剂
US10900055B2 (en) 2018-06-12 2021-01-26 Codexis, Inc. Engineered tyrosine ammonia lyase
IL279884B2 (en) 2018-07-09 2026-04-01 Codexis Inc Engineered pantothenate kinase variant enzymes
EP3821015A4 (en) 2018-07-09 2022-07-13 Codexis, Inc. GENETIC DEOXYRIBOSE PHOSPHATE ALDOLASES
AU2019302423B2 (en) 2018-07-09 2024-11-21 Codexis, Inc. Engineered purine nucleoside phosphorylase variant enzymes
SG11202012138XA (en) 2018-07-09 2021-01-28 Codexis Inc Engineered galactose oxidase variant enzymes
EP3821026A4 (en) 2018-07-09 2022-06-01 Codexis, Inc. MANIPULATED ENZYME VARIANTS OF PHOSPHOPENTOMUTASE
JP2021531749A (ja) 2018-07-12 2021-11-25 コデクシス， インコーポレイテッド 操作されたフェニルアラニンアンモニアリアーゼポリペプチド
WO2020028039A1 (en) 2018-07-30 2020-02-06 Codexis, Inc. Engineered glycosyltransferases and steviol glycoside glucosylation methods
AU2019373208A1 (en) 2018-10-29 2021-05-13 Codexis, Inc. Engineered DNA polymerase variants
CA3122524A1 (en) 2018-12-14 2020-06-18 Codexis, Inc. Engineered tyrosine ammonia lyase
AU2019403323B2 (en) 2018-12-20 2026-02-26 Codexis, Inc. Human alpha-galactosidase variants
CA3126671A1 (en) 2019-01-15 2020-07-23 Codexis, Inc. Engineered transaminase polypeptides
CN114096662B (zh) 2019-05-01 2025-04-15 科德克希思公司 工程化葡萄糖脱氢酶和用于酮和胺化合物的还原胺化的方法
EP3963057A4 (en) 2019-05-01 2023-06-14 Codexis, Inc. MANIPULATED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION OF KETONE AND AMINE COMPOUNDS
AU2020299358A1 (en) 2019-07-02 2021-12-23 Codexis, Inc. Engineered acetate kinase variant enzymes
WO2021003132A1 (en) 2019-07-02 2021-01-07 Codexis, Inc. Engineered sucrose phosphorylase variant enzymes
US20230173066A1 (en) 2019-07-23 2023-06-08 Frieslandcampina Nederland B.V. Nutritional composition comprising milk fat and immunoglobulin
EP4501403A3 (en) 2019-08-30 2025-05-14 Société des Produits Nestlé S.A. Engineered lipase variants
US12012620B2 (en) 2019-09-12 2024-06-18 Codexis, Inc. Peroxidase activity towards 10-acetyl-3,7-dihydroxyphenoxazine
CN114746745B (zh) 2019-10-02 2025-06-17 美国雅培糖尿病护理公司 通过蛋白质开关检测分析物
CN121780457A (zh) 2019-11-26 2026-04-03 科德克希思公司 用于化学化合物的羟基化的生物催化剂和方法
JP2023507575A (ja) 2019-12-20 2023-02-24 コデクシス， インコーポレイテッド 操作された酸性アルファ－グルコシダーゼバリアント
JP2023512683A (ja) 2020-02-04 2023-03-28 コデクシス， インコーポレイテッド 操作されたロイシンデカルボキシラーゼ
EP4133064A4 (en) 2020-04-10 2024-07-24 Codexis, Inc. Engineered transaminase polypeptides
JP7747337B2 (ja) 2020-04-10 2025-10-01 コデクシス， インコーポレイテッド 速度論的光学分割のためのカルボキシエステラーゼポリペプチド
CN116897205A (zh) 2020-08-28 2023-10-17 科德克希思公司 工程化淀粉酶变体
AU2021334371A1 (en) 2020-08-28 2023-03-09 Codexis, Inc. Engineered protease variants
US20220186231A1 (en) 2020-12-11 2022-06-16 Willow Biosciences, Inc. Recombinant acyl activating enzyme (aae) genes for enhanced biosynthesis of cannabinoids and cannabinoid precursors
WO2022133289A2 (en) 2020-12-18 2022-06-23 Codexis, Inc. Engineered uridine phosphorylase variant enzymes
EP4314262A1 (en) 2021-04-02 2024-02-07 Codexis, Inc. Engineered guanylate kinase variant enzymes
US12180483B2 (en) 2021-04-02 2024-12-31 Codexis, Inc. Engineered cyclic GMP-AMP synthase (cGAS) variant enzymes
IL305919A (en) 2021-04-02 2023-11-01 Codexis Inc Engineered adenylate kinase variant enzymes
CA3215105A1 (en) 2021-04-02 2022-10-06 Codexis, Inc. Engineered acetate kinase variant enzymes
CA3220735A1 (en) 2021-05-21 2022-11-24 Codexis, Inc. Engineered methionine gamma lyase variants
CA3227215A1 (en) 2021-07-30 2023-02-02 Trish Choudhary Recombinant prenyltransferase polypeptides engineered for enhanced biosynthesis of cannabinoids
EP4388088A1 (en) 2021-08-19 2024-06-26 Willow Biosciences, Inc. Recombinant olivetolic acid cyclase polypeptides engineered for enhanced biosynthesis of cannabinoids
US12129495B2 (en) 2021-10-15 2024-10-29 Codexis, Inc. Engineered DNA polymerase variants
CA3234383A1 (en) 2021-10-15 2023-04-27 Codexis, Inc. Engineered terminal deoxynucleotidyl transferase variants
WO2023069921A1 (en) 2021-10-19 2023-04-27 Epimeron Usa, Inc. Recombinant thca synthase polypeptides engineered for enhanced biosynthesis of cannabinoids
JP2024540358A (ja) 2021-11-01 2024-10-31 シンティス バイオ，インコーポレイティド 工学操作ロイシン脱炭酸酵素
JP2025510621A (ja) 2022-03-31 2025-04-15 青島清原化合物有限公司 モノアミン酸化酵素及びその応用
WO2024040020A1 (en) 2022-08-15 2024-02-22 Absci Corporation Quantitative affinity activity specific cell enrichment
CN120981566A (zh) 2023-01-12 2025-11-18 诺华股份有限公司 工程化酮还原酶多肽
WO2025061911A1 (en) 2023-09-22 2025-03-27 Glaxosmithkline Intellectual Property Development Limited Methods of producing nucleotide triphosphates (ntps)
WO2025144700A1 (en) 2023-12-27 2025-07-03 Absci Corporation Nanobody library screening using bacterial surface display
WO2025235589A1 (en) 2024-05-08 2025-11-13 Codexis, Inc. Dna polymerase variants
WO2025242702A1 (en) 2024-05-23 2025-11-27 Glaxosmithkline Intellectual Property Development Limited Enzymatic process for producing n-acetyl galactosamine clusters
CN121450551A (zh) * 2026-01-07 2026-02-03 善恩康生物科技（苏州）有限公司 具有抗炎活性的沙棘源益生菌及其在肠炎治疗中的应用和产品

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3886288A (en) * 1970-06-15 1975-05-27 Swift & Co Cheese manufacture using highly active proteolytic enzymes
JPS5279086A (en) 1975-12-25 1977-07-02 Nippon Soda Co Ltd Preparation of antibiotic tunicamycin
JPS5279083A (en) * 1975-12-26 1977-07-02 Morinaga Milk Industry Co Ltd Production of protein decomposed substance not having bitterness and antigen property
JPS6041751B2 (ja) 1976-06-22 1985-09-18 ジエコ−株式会社 デジタル電子時計
JPS548785A (en) 1977-06-21 1979-01-23 Kikkoman Corp Preparation of protein hydrolyzate
US4839281A (en) † 1985-04-17 1989-06-13 New England Medical Center Hospitals, Inc. Lactobacillus strains and methods of selection
DK589785A (da) * 1985-12-18 1987-06-19 Samuelsson Ernst Gunnar Peptidpraeparat, fremgangsmaade til fremstilling deraf samt anvendelse af peptidpraeparatet
ATE84680T1 (de) † 1987-12-23 1993-02-15 Nestle Sa Verfahren zur herstellung eines molkeeiweisshydrolysates und eines hypoallergenen nahrungsmittels.
DD281540A5 (de) * 1988-08-08 1990-08-15 Berlin Chemie Veb Verfahren zur herstellung von nutritiva
ES2063882T5 (es) † 1989-10-02 2001-12-01 Novartis Nutrition Ag Hidrolizados de proteinas.
JP3071877B2 (ja) † 1991-06-27 2000-07-31 財団法人糧食研究会 経口寛容誘導能を有する低アレルゲン性酵素分解ペプチド組成物
US5952034A (en) * 1991-10-12 1999-09-14 The Regents Of The University Of California Increasing the digestibility of food proteins by thioredoxin reduction
ATE161181T1 (de) * 1992-07-06 1998-01-15 Nestle Sa Lactobacillus acidophilus enthaltende antigastritis-mittel
FI94089C (fi) 1992-12-10 1995-07-25 Valio Oy Menetelmä allergiaa aiheuttavien yhdisteiden poistamiseksi proteiinipitoisista koostumuksista
RU2031586C1 (ru) 1993-02-05 1995-03-27 Тамара Георгиевна Извекова Биологически активный кисломолочный продукт "ацидолакт-наринэ" и способ его получения
GB9312369D0 (en) 1993-06-16 1993-07-28 Sandoz Nutrition Ltd Organic compounds
WO1995014485A1 (en) 1993-11-23 1995-06-01 Kabushiki Kaisha Wado Doctors Group Intestinal flora improver composition, and apparatus and system for producing the same
FI104465B (fi) * 1995-06-14 2000-02-15 Valio Oy Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö

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