GR1002545B - Μεθοδος παρασκευης νεων συνθεσεων ινσουλινης. - Google Patents

Μεθοδος παρασκευης νεων συνθεσεων ινσουλινης.

Info

Publication number
GR1002545B
GR1002545B GR900100206A GR900100206A GR1002545B GR 1002545 B GR1002545 B GR 1002545B GR 900100206 A GR900100206 A GR 900100206A GR 900100206 A GR900100206 A GR 900100206A GR 1002545 B GR1002545 B GR 1002545B
Authority
GR
Greece
Prior art keywords
preparing new
insulin compositions
new insulin
compositions
preparing
Prior art date
Application number
GR900100206A
Other languages
English (en)
Other versions
GR900100206A (el
Inventor
Benned Finn Hansen
Per Balschmidt
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Publication of GR900100206A publication Critical patent/GR900100206A/el
Publication of GR1002545B publication Critical patent/GR1002545B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GR900100206A 1989-03-20 1990-03-20 Μεθοδος παρασκευης νεων συνθεσεων ινσουλινης. GR1002545B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK134189A DK134189D0 (da) 1989-03-20 1989-03-20 Insulinforbindelser

Publications (2)

Publication Number Publication Date
GR900100206A GR900100206A (el) 1991-07-31
GR1002545B true GR1002545B (el) 1997-01-28

Family

ID=8103787

Family Applications (1)

Application Number Title Priority Date Filing Date
GR900100206A GR1002545B (el) 1989-03-20 1990-03-20 Μεθοδος παρασκευης νεων συνθεσεων ινσουλινης.

Country Status (23)

Country Link
US (1) US5430016A (el)
EP (1) EP0463072B1 (el)
JP (1) JPH04503808A (el)
KR (1) KR920701250A (el)
CN (1) CN1045793A (el)
AT (1) ATE116661T1 (el)
AU (1) AU637365B2 (el)
CA (1) CA2049961A1 (el)
DD (1) DD298788A5 (el)
DE (1) DE69015811T2 (el)
DK (2) DK134189D0 (el)
ES (1) ES2068384T3 (el)
FI (1) FI914419A7 (el)
GR (1) GR1002545B (el)
HU (1) HUT58349A (el)
IE (1) IE66564B1 (el)
IL (1) IL93792A0 (el)
NO (1) NO300640B1 (el)
NZ (1) NZ232953A (el)
PT (1) PT93502B (el)
WO (1) WO1990011299A1 (el)
YU (1) YU53290A (el)
ZA (1) ZA902086B (el)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH25772A (en) * 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
US5304473A (en) * 1991-06-11 1994-04-19 Eli Lilly And Company A-C-B proinsulin, method of manufacturing and using same, and intermediates in insulin production
TW224471B (el) * 1991-11-26 1994-06-01 Lilly Co Eli
US5948751A (en) * 1996-06-20 1999-09-07 Novo Nordisk A/S X14-mannitol
JP2001521004A (ja) 1997-10-24 2001-11-06 イーライ・リリー・アンド・カンパニー 脂肪酸−アシル化インスリン類似体
CO4970787A1 (es) * 1997-12-23 2000-11-07 Lilly Co Eli Composiciones insolubles de insulina y derivados de insulina que controlan la glucosa sanguinea
US7378390B2 (en) * 1999-12-29 2008-05-27 Novo Nordisk A/S Method for making insulin precursors and insulin precursor analogues having improved fermentation yield in yeast
CZ2004710A3 (cs) * 2001-12-20 2005-02-16 Eli Lilly And Company Inzulínová sloučenina s protrahovaným účinkem
US20060217290A1 (en) * 2003-04-29 2006-09-28 Kohn Wayne D Insulin analogs having protracted time action
US8827979B2 (en) * 2007-03-19 2014-09-09 Insuline Medical Ltd. Drug delivery device
US8622991B2 (en) 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
US9220837B2 (en) 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
ES2432404T3 (es) * 2007-03-19 2013-12-03 Insuline Medical Ltd. Método y dispositivo para medida de sustancias
US8409133B2 (en) * 2007-12-18 2013-04-02 Insuline Medical Ltd. Drug delivery device with sensor for closed-loop operation
AU2009203809B2 (en) 2008-01-09 2013-07-25 Sanofi-Aventis Deutschland Gmbh Novel insulin derivatives having an extremely delayed time-action profile
BRPI0907119A2 (pt) * 2008-01-09 2015-07-14 Sanofi Aventis Deutschland Derivados de insulina tendo um perfil de ação de tempo extremamente retardado
PT3228320T (pt) 2008-10-17 2020-03-26 Sanofi Aventis Deutschland Combinação de uma insulina e de um agonista do glp-1
EP2355758A2 (en) 2008-11-07 2011-08-17 Insuline Medical Ltd. Device and method for drug delivery
KR101853606B1 (ko) 2009-07-06 2018-05-03 사노피-아벤티스 도이칠란트 게엠베하 메티오닌을 함유하는 수성 인슐린 제제
DK2498802T3 (en) 2009-11-13 2015-04-13 Sanofi Aventis Deutschland Pharmaceutical composition comprising a GLP-1 agonist, insulin and a methionine
KR101337322B1 (ko) 2009-11-13 2013-12-06 사노피-아벤티스 도이칠란트 게엠베하 Ｇｌｐ-1 효능제 및 메티오닌을 포함하는 약제학적 조성물
ES2606554T3 (es) 2010-08-30 2017-03-24 Sanofi-Aventis Deutschland Gmbh Uso de AVE0010 para la fabricación de un medicamento para el tratamiento de la diabetes mellitus de tipo 2
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
PL2750699T3 (pl) 2011-08-29 2015-12-31 Sanofi Aventis Deutschland Kombinacja farmaceutyczna do stosowania w kontroli glikemii u pacjentów z cukrzycą typu 2
AR087744A1 (es) 2011-09-01 2014-04-16 Sanofi Aventis Deutschland Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
SG11201508469YA (en) 2013-05-02 2015-11-27 Glaxosmithkline Ip Dev Ltd Therapeutic peptides
AU2015359376B2 (en) 2014-12-12 2021-09-09 Sanofi-Aventis Deutschland Gmbh Insulin glargine/lixisenatide fixed ratio formulation
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
CN106323840A (zh) * 2016-09-13 2017-01-11 西南石油大学 一种页岩孔隙度测量方法
CN109735589B (zh) * 2019-01-02 2020-07-10 珠海冀百康生物科技有限公司 一种胰岛素DesB30的制备方法
CN113773398B (zh) * 2020-06-10 2023-05-23 宁波鲲鹏生物科技有限公司 一种德谷胰岛素衍生物及其应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
US4343898A (en) * 1980-02-11 1982-08-10 Novo Industri A/S Process for preparing esters of human insulin
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DE3326473A1 (de) * 1983-07-22 1985-01-31 Hoechst Ag, 6230 Frankfurt Pharmazeutisches mittel zur behandlung des diabetes mellitus
DE3326472A1 (de) * 1983-07-22 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DK58285D0 (da) * 1984-05-30 1985-02-08 Novo Industri As Peptider samt fremstilling og anvendelse deraf
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
US4946828A (en) * 1985-03-12 1990-08-07 Novo Nordisk A/S Novel insulin peptides
US5008241A (en) * 1985-03-12 1991-04-16 Novo Nordisk A/S Novel insulin peptides
DK347086D0 (da) * 1986-07-21 1986-07-21 Novo Industri As Novel peptides
DK119785D0 (da) * 1985-03-15 1985-03-15 Nordisk Gentofte Insulinpraeparat
DK129385A (da) * 1985-03-22 1986-09-23 Novo Industri As Peptider og fremstilling deraf
DK437786D0 (da) * 1986-09-12 1986-09-12 Nordisk Gentofte Insulinprecursorer
DE3717370A1 (de) * 1987-05-22 1988-12-01 Hoechst Ag Mischkristalle aus insulin und insulinderivaten, verfahren zur herstellung dieser mischkristalle, diese mischkristalle enthaltende pharmazeutische mittel und ihre verwendung zur behandlung von diabetes mellitus
DK336188D0 (da) * 1988-06-20 1988-06-20 Nordisk Gentofte Propeptider
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung

Also Published As

Publication number Publication date
DE69015811D1 (de) 1995-02-16
ATE116661T1 (de) 1995-01-15
PT93502B (pt) 1996-02-29
EP0463072A1 (en) 1992-01-02
IE901004L (en) 1990-09-20
PT93502A (pt) 1990-11-07
NZ232953A (en) 1992-10-28
US5430016A (en) 1995-07-04
DE69015811T2 (de) 1995-05-11
KR920701250A (ko) 1992-08-11
IL93792A0 (en) 1990-12-23
GR900100206A (el) 1991-07-31
CA2049961A1 (en) 1990-09-21
FI914419A0 (fi) 1991-09-19
FI914419A7 (fi) 1991-09-19
DK0463072T3 (da) 1995-06-12
WO1990011299A1 (en) 1990-10-04
CN1045793A (zh) 1990-10-03
IE66564B1 (en) 1996-01-24
AU5344890A (en) 1990-10-22
NO913687L (no) 1991-11-19
HU902706D0 (en) 1991-12-30
EP0463072B1 (en) 1995-01-04
YU53290A (sh) 1992-12-21
NO913687D0 (no) 1991-09-19
DD298788A5 (de) 1992-03-12
AU637365B2 (en) 1993-05-27
ES2068384T3 (es) 1995-04-16
NO300640B1 (no) 1997-06-30
JPH04503808A (ja) 1992-07-09
ZA902086B (en) 1990-11-28
DK134189D0 (da) 1989-03-20
HUT58349A (en) 1992-02-28

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