GR1002545B - Μεθοδος παρασκευης νεων συνθεσεων ινσουλινης. - Google Patents

Μεθοδος παρασκευης νεων συνθεσεων ινσουλινης.

Info

Publication number
GR1002545B
GR1002545B GR900100206A GR900100206A GR1002545B GR 1002545 B GR1002545 B GR 1002545B GR 900100206 A GR900100206 A GR 900100206A GR 900100206 A GR900100206 A GR 900100206A GR 1002545 B GR1002545 B GR 1002545B
Authority
GR
Greece
Prior art keywords
preparing new
insulin compositions
new insulin
compositions
preparing
Prior art date
Application number
GR900100206A
Other languages
English (en)
Other versions
GR900100206A (el
Inventor
Benned Finn Hansen
Per Balschmidt
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Publication of GR900100206A publication Critical patent/GR900100206A/el
Publication of GR1002545B publication Critical patent/GR1002545B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GR900100206A 1989-03-20 1990-03-20 Μεθοδος παρασκευης νεων συνθεσεων ινσουλινης. GR1002545B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK134189A DK134189D0 (da) 1989-03-20 1989-03-20 Insulinforbindelser

Publications (2)

Publication Number Publication Date
GR900100206A GR900100206A (el) 1991-07-31
GR1002545B true GR1002545B (el) 1997-01-28

Family

ID=8103787

Family Applications (1)

Application Number Title Priority Date Filing Date
GR900100206A GR1002545B (el) 1989-03-20 1990-03-20 Μεθοδος παρασκευης νεων συνθεσεων ινσουλινης.

Country Status (23)

Country Link
US (1) US5430016A (el)
EP (1) EP0463072B1 (el)
JP (1) JPH04503808A (el)
KR (1) KR920701250A (el)
CN (1) CN1045793A (el)
AT (1) ATE116661T1 (el)
AU (1) AU637365B2 (el)
CA (1) CA2049961A1 (el)
DD (1) DD298788A5 (el)
DE (1) DE69015811T2 (el)
DK (2) DK134189D0 (el)
ES (1) ES2068384T3 (el)
FI (1) FI914419A7 (el)
GR (1) GR1002545B (el)
HU (1) HUT58349A (el)
IE (1) IE66564B1 (el)
IL (1) IL93792A0 (el)
NO (1) NO300640B1 (el)
NZ (1) NZ232953A (el)
PT (1) PT93502B (el)
WO (1) WO1990011299A1 (el)
YU (1) YU53290A (el)
ZA (1) ZA902086B (el)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH25772A (en) * 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
US5304473A (en) * 1991-06-11 1994-04-19 Eli Lilly And Company A-C-B proinsulin, method of manufacturing and using same, and intermediates in insulin production
TW224471B (el) * 1991-11-26 1994-06-01 Lilly Co Eli
US5948751A (en) * 1996-06-20 1999-09-07 Novo Nordisk A/S X14-mannitol
EA200000453A1 (ru) 1997-10-24 2000-10-30 Эли Лилли Энд Компани Композиции нерастворимого инсулина
US6531448B1 (en) 1997-12-23 2003-03-11 Eli Lilly And Company Insoluble compositions for controlling blood glucose
US7378390B2 (en) * 1999-12-29 2008-05-27 Novo Nordisk A/S Method for making insulin precursors and insulin precursor analogues having improved fermentation yield in yeast
PL374949A1 (en) * 2001-12-20 2005-11-14 Eli Lilly And Company Insulin molecule having protracted time action
US20060217290A1 (en) * 2003-04-29 2006-09-28 Kohn Wayne D Insulin analogs having protracted time action
US20100292557A1 (en) * 2007-03-19 2010-11-18 Benny Pesach Method and device for substance measurement
US8622991B2 (en) 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
MX2009010000A (es) * 2007-03-19 2010-03-17 Insuline Medical Ltd Dispositivo para el suministro de farmaco.
US9220837B2 (en) 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
US8409133B2 (en) 2007-12-18 2013-04-02 Insuline Medical Ltd. Drug delivery device with sensor for closed-loop operation
CN102007143B (zh) 2008-01-09 2015-08-26 塞诺菲-安万特德国有限公司 具有超延迟时效特征的新型胰岛素衍生物
EP2229406B1 (de) * 2008-01-09 2015-04-22 Sanofi-Aventis Deutschland GmbH Neue insulinderivate mit extrem verzögertem zeit- / wirkungsprofil
CN102256618A (zh) 2008-10-17 2011-11-23 赛诺菲-安万特德国有限公司 胰岛素和glp-1激动剂的组合
CA2743027C (en) 2008-11-07 2016-04-12 Insuline Medical Ltd. Device and method for drug delivery
PL2451437T3 (pl) 2009-07-06 2017-05-31 Sanofi-Aventis Deutschland Gmbh Wodne preparaty insuliny zawierające metioninę
TR201809460T4 (tr) 2009-11-13 2018-07-23 Sanofi Aventis Deutschland Bir GLP- 1-agonisti, bir insülin ve metiyonin içeren farmasötik bileşim.
NZ599847A (en) 2009-11-13 2013-09-27 Sanofi Aventis Deutschland Pharmaceutical composition comprising a glp-1 agonist and methionine
WO2012028172A1 (en) 2010-08-30 2012-03-08 Sanofi-Aventis Deutschland Gmbh Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
AR087693A1 (es) 2011-08-29 2014-04-09 Sanofi Aventis Deutschland Combinacion farmaceutica para uso en el control glucemico en pacientes con diabetes de tipo 2
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
SG11201508469YA (en) 2013-05-02 2015-11-27 Glaxosmithkline Ip Dev Ltd Therapeutic peptides
PE20171622A1 (es) 2014-12-12 2017-11-02 Sanofi Aventis Deutschland Formulacion de relacion fija de insulina glargina/lixisenatida
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
CN106323840A (zh) * 2016-09-13 2017-01-11 西南石油大学 一种页岩孔隙度测量方法
CN109735589B (zh) * 2019-01-02 2020-07-10 珠海冀百康生物科技有限公司 一种胰岛素DesB30的制备方法
CN113773398B (zh) * 2020-06-10 2023-05-23 宁波鲲鹏生物科技有限公司 一种德谷胰岛素衍生物及其应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
IE50892B1 (en) * 1980-02-11 1986-08-06 Novo Industri As Process for preparing insulin esters
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DE3326473A1 (de) * 1983-07-22 1985-01-31 Hoechst Ag, 6230 Frankfurt Pharmazeutisches mittel zur behandlung des diabetes mellitus
DE3326472A1 (de) * 1983-07-22 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DK58285D0 (da) * 1984-05-30 1985-02-08 Novo Industri As Peptider samt fremstilling og anvendelse deraf
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
US5008241A (en) * 1985-03-12 1991-04-16 Novo Nordisk A/S Novel insulin peptides
DK347086D0 (da) * 1986-07-21 1986-07-21 Novo Industri As Novel peptides
US4946828A (en) * 1985-03-12 1990-08-07 Novo Nordisk A/S Novel insulin peptides
DK119785D0 (da) * 1985-03-15 1985-03-15 Nordisk Gentofte Insulinpraeparat
DK129385A (da) * 1985-03-22 1986-09-23 Novo Industri As Peptider og fremstilling deraf
DK437786D0 (da) * 1986-09-12 1986-09-12 Nordisk Gentofte Insulinprecursorer
DE3717370A1 (de) * 1987-05-22 1988-12-01 Hoechst Ag Mischkristalle aus insulin und insulinderivaten, verfahren zur herstellung dieser mischkristalle, diese mischkristalle enthaltende pharmazeutische mittel und ihre verwendung zur behandlung von diabetes mellitus
DK336188D0 (da) * 1988-06-20 1988-06-20 Nordisk Gentofte Propeptider
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung

Also Published As

Publication number Publication date
DE69015811T2 (de) 1995-05-11
DE69015811D1 (de) 1995-02-16
DK0463072T3 (da) 1995-06-12
EP0463072A1 (en) 1992-01-02
AU637365B2 (en) 1993-05-27
NO913687L (no) 1991-11-19
YU53290A (sh) 1992-12-21
CA2049961A1 (en) 1990-09-21
IE901004L (en) 1990-09-20
NO913687D0 (no) 1991-09-19
DD298788A5 (de) 1992-03-12
GR900100206A (el) 1991-07-31
IL93792A0 (en) 1990-12-23
CN1045793A (zh) 1990-10-03
EP0463072B1 (en) 1995-01-04
HU902706D0 (en) 1991-12-30
JPH04503808A (ja) 1992-07-09
US5430016A (en) 1995-07-04
NO300640B1 (no) 1997-06-30
KR920701250A (ko) 1992-08-11
AU5344890A (en) 1990-10-22
ATE116661T1 (de) 1995-01-15
ZA902086B (en) 1990-11-28
HUT58349A (en) 1992-02-28
WO1990011299A1 (en) 1990-10-04
ES2068384T3 (es) 1995-04-16
FI914419A0 (fi) 1991-09-19
PT93502B (pt) 1996-02-29
IE66564B1 (en) 1996-01-24
NZ232953A (en) 1992-10-28
DK134189D0 (da) 1989-03-20
PT93502A (pt) 1990-11-07
FI914419A7 (fi) 1991-09-19

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