GR3005155T3 - - Google Patents

Info

Publication number
GR3005155T3
GR3005155T3 GR920401500T GR920401500T GR3005155T3 GR 3005155 T3 GR3005155 T3 GR 3005155T3 GR 920401500 T GR920401500 T GR 920401500T GR 920401500 T GR920401500 T GR 920401500T GR 3005155 T3 GR3005155 T3 GR 3005155T3
Authority
GR
Greece
Prior art keywords
alkyl
aralkyl
alkoxy
hydroxy
amino
Prior art date
Application number
GR920401500T
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GR3005155T3 publication Critical patent/GR3005155T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06156—Dipeptides with the first amino acid being heterocyclic and Trp-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
GR920401500T 1985-12-31 1992-07-13 GR3005155T3 (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/815,217 US4814463A (en) 1985-12-31 1985-12-31 CCK antagonists

Publications (1)

Publication Number Publication Date
GR3005155T3 true GR3005155T3 (el) 1993-05-24

Family

ID=25217199

Family Applications (1)

Application Number Title Priority Date Filing Date
GR920401500T GR3005155T3 (el) 1985-12-31 1992-07-13

Country Status (8)

Country Link
US (1) US4814463A (el)
EP (1) EP0230151B1 (el)
JP (1) JPH0755927B2 (el)
AT (1) ATE76411T1 (el)
CA (1) CA1294737C (el)
DE (1) DE3685425D1 (el)
ES (1) ES2039205T3 (el)
GR (1) GR3005155T3 (el)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03503650A (ja) * 1988-04-05 1991-08-15 アボツト・ラボラトリーズ Ｃｃｋアンタゴニストとしてのトリプトファン誘導体
CA1326108C (en) * 1988-04-12 1994-01-11 Sun Hyuk Kim Cck antagonists
US5010089A (en) * 1988-08-12 1991-04-23 Biomeasure, Inc. CCK antagonists and their use in treating gastrointestinal disorders
US5631281A (en) * 1989-06-29 1997-05-20 Warner-Lambert Company N-substituted cycloalkyl and polycycloalkyl α-substituted Trp-Phe- and phenethylamine derivatives
US5278316A (en) * 1989-06-29 1994-01-11 Warner-Lambert Company N-substituted cycloalkyl and polycycloalkyl alpha-substituted Trp-Phe- and phenethylamine derivatives
NZ234264A (en) * 1989-06-29 1993-05-26 Warner Lambert Co N-substituted cycloalkyl and polycycloalkyl alpha-substituted trp-phe- and phenethylamine derivatives, and pharmaceutical compositions
FR2659966B1 (fr) * 1990-03-26 1992-05-22 Rhone Poulenc Sante Derives de n-aralkyl glycinamide, leur preparation et les medicaments les contenant.
WO1991013874A1 (fr) * 1990-03-07 1991-09-19 Rhone-Poulenc Rorer S.A. Derives de glycinamide, leur preparation et les medicaments les contenant
FR2667066B2 (fr) * 1990-03-07 1993-06-25 Rhone Poulenc Sante N-heterocyclyl glycinamides, leur preparation et les medicaments les contenant.
US5593967A (en) * 1990-08-31 1997-01-14 Warner-Lambert Company Cholecystokinin antagonists, their preparation and therapeutic use
US5264419A (en) * 1990-08-31 1993-11-23 Warner-Lambert Company N-substituted cycloalkyl and polycycloalkyl α-substituted TRP derivatives
US5244915A (en) * 1990-08-31 1993-09-14 Warner-Lambert Company Amico acid derivatives cyclized at the c-terminal
CA2088195A1 (en) * 1990-08-31 1992-03-01 David C. Horwell Cholecystokinin antagonists, their preparation and therapeutic use
WO1992004321A1 (en) * 1990-09-10 1992-03-19 Rhone-Poulenc Rorer International (Holdings) Inc. Substituted bicyclic aryl compounds exhibiting selective leukotriene b4 antagonist activity
US5239083A (en) * 1991-03-11 1993-08-24 Kyowa Hakko Kogyo Co., Ltd. Indole derivatives which inhibit steroid 5α reductase
WO1993001169A2 (en) * 1991-07-05 1993-01-21 Merck Sharp & Dohme Limited Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
US5218123A (en) * 1992-02-18 1993-06-08 Warner-Lambert Company Didehydrotryptophan derivatives and pharmaceutical use thereof
US5328927A (en) * 1992-03-03 1994-07-12 Merck Sharpe & Dohme, Ltd. Hetercyclic compounds, processes for their preparation and pharmaceutical compositions containing them
PT720601E (pt) * 1993-08-10 2001-02-28 Black James Foundation Ligandos de receptores de gastrina e cck
US6869957B1 (en) 1993-11-17 2005-03-22 Eli Lilly And Company Non-peptide tachykinin receptor antagonists
US6403577B1 (en) 1993-11-17 2002-06-11 Eli Lilly And Company Hexamethyleneiminyl tachykinin receptor antagonists
US20060258647A1 (en) * 2005-05-04 2006-11-16 The Regents Of The University Of California Treatment of maladaptive substance use with cholecystokinin (CCK) antagonists

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH343407A (fr) * 1955-07-01 1959-12-31 Uclaf Societe Anonyme Procédé de préparation de peptides
US4000297A (en) * 1971-05-18 1976-12-28 Rotta Research Laboratorium S.P.A. N-p-chlorobenzoyl tryptophane, salts and compositions thereof
DE2853825A1 (de) * 1978-12-13 1980-07-03 Troponwerke Gmbh & Co Kg Pharmazeutisch wirksame dipeptide
US4356118A (en) * 1981-06-02 1982-10-26 G. D. Searle & Co. Tryptophan derivatives
US4482567A (en) * 1982-10-07 1984-11-13 Research Foundation For Mental Hygiene, Inc. N-hexanoyl to n-heptadecanoyl 5-hydroxy tryptophan-5-hydroxytryptophanamides and use as analgesics
FR2546517B1 (fr) * 1983-05-24 1987-04-24 Panmedica Nouveaux dipeptides du -l-5-hydroxy-tryptophane, procedes pour leur preparation et medicaments les contenant
IT1179866B (it) * 1984-12-12 1987-09-16 Rotta Research Lab Derivati del triptofano farmaceuticamente attivi e composizioni farmaceutiche che li contengono

Also Published As

Publication number Publication date
CA1294737C (en) 1992-01-21
JPS62175461A (ja) 1987-08-01
EP0230151B1 (en) 1992-05-20
JPH0755927B2 (ja) 1995-06-14
ATE76411T1 (de) 1992-06-15
US4814463A (en) 1989-03-21
DE3685425D1 (de) 1992-06-25
EP0230151A2 (en) 1987-07-29
EP0230151A3 (en) 1989-02-01
ES2039205T3 (es) 1993-09-16

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