HRP20190761T1 - Bakterija za upotrebu kao probiotik za nutritivne i medicinske primjene - Google Patents
Bakterija za upotrebu kao probiotik za nutritivne i medicinske primjene Download PDFInfo
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
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- A—HUMAN NECESSITIES
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- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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Claims (18)
1. Bakterijski soj koji ima
(a) 16S rRNK identitet od barem 99.5% sa sojem koji pripada vrsti Roseburia hominis položenoj pod pristupnim brojem NCIMB 14029, ili
(b) DNK-DNK homologiju barem 95% identičnu s bakterijskim sojem koji pripada vrsti Roseburia hominis položenoj pod pristupnim brojem NCIMB 14029
za upotrebu u medicini.
2. Farmaceutski sastav koji sadrži bakterijski soj koji ima (a) 16S rRNK identitet od barem 99.5% sa sojem koji pripada vrsti Roseburia hominis položenoj pod pristupnim brojem NCIMB 14029, ili (b) DNK-DNK homologiju barem 95% identičnu s bakterijskim sojem koji pripada vrsti Roseburia hominis položenoj pod pristupnim brojem NCIMB 14029 i farmaceutski prihvatljivu pomoćnu tvar, nosač ili razrjeđivač.
3. Nutritivni dodatak koji sadrži bakterijski soj koji ima (a) 16S rRNK identitet od barem 99.5% sa sojem koji pripada vrsti Roseburia hominis položenoj pod pristupnim brojem NCIMB 14029, ili (b) DNK-DNK homologiju barem 95% identičnu s bakterijskim sojem koji pripada vrsti Roseburia hominis položenoj pod pristupnim brojem NCIMB 14029 i nutritivno prihvatljivu pomoćnu tvar, nosač ili razrjeđivač.
4. Probiotski sastav, hrana za životinje, prehrambeni proizvod, dijetetski suplement ili dodatak prehrani koji sadrži bakterijski soj koji ima (a) 16S rRNK identitet od barem 99.5% sa sojem koji pripada vrsti Roseburia hominis položenoj pod pristupnim brojem NCIMB 14029, ili (b) DNK-DNK homologiju barem 95% identičnu s bakterijskim sojem koji pripada vrsti Roseburia hominis položenoj pod pristupnim brojem NCIMB 14029.
5. Bakterijski soj za upotrebu prema zahtjevu 1 ili farmaceutski sastav, nutritivni dodatak, probiotski sastav, hrana za životinje, prehrambeni proizvod, dijetetski suplement ili dodatak prehrani prema bilo kojem od zahtjeva 2-4, pri čemu bakterijski soj je soj koji pripada vrsti Roseburia hominis položenoj pod pristupnim brojem NCIMB 14029.
6. Bakterijski soj za upotrebu prema zahtjevu 1 ili farmaceutski sastav, nutritivni dodatak, probiotski sastav, hrana za životinje, prehrambeni proizvod, dijetetski suplement ili dodatak prehrani prema bilo kojem od zahtjeva 2-4, pri čemu bakterijski soj ima genom koji se sastoji od 3,592,125-bp kromosoma sa četiri ribosomna operona, 66 RNK i 3,273 predviđenih proteina.
7. Bakterijski soj za upotrebu prema zahtjevu 1 ili farmaceutski sastav, nutritivni dodatak, probiotski sastav, hrana za životinje, prehrambeni proizvod, dijetetski suplement ili dodatak prehrani prema bilo kojem od zahtjeva 2-4, pri čemu je bakterijski soj u obliku liofilizirane populacije bakterija.
8. Bakterijski soj za upotrebu prema zahtjevu 1 ili zahtjevu 5, naznačen time da je soj za upotrebu u regulaciji imunološkog sustava subjekta.
9. Bakterijski soj za upotrebu prema zahtjevu 8, naznačen time da je regulacija imunološkog sustava regulacija urođenog imunološkog sustava subjekta.
10. Bakterijski soj za upotrebu prema zahtjevu 1 ili 5, naznačen time da se soj koristi za tretman poremećaja odabranog od upalnog poremećaja, poremećaja imuniteta i intestinalnog poremećaja kao što je poremećaj odabran između: sindroma iritabilnog crijeva (IBS), kolitisa, upalnog oboljenja crijeva (IBD), uključujući Chronovu bolest i ulcerozni kolitis, upalu ilealnog spremnika, funkcionalnu dispepsiju, funkcionalnu konstipaciju, funkcionalnu dijareju, uključujući sa antibioticima povezanu dijareju, putničku dijareju i pedijatrijsku dijareju, funkcionalnu abdominalnu bol, funkcionalnu nadutost, sindrom epigastrične boli, sindrom postprandijalnog distresa, gastrointestinalnu refluksnu bolest (GERD), autoimune bolesti kao što su dijabetes, artritis, multipla skleroza i psorijaza, alergije, atopične bolesti kao npr. atopijski dermatitis, nekrotizirajući enterokolitis, druge infekcije, celijakija, i rinitis i njihove kombinacije.
11. Bakterijski soj za upotrebu prema zahtjevu 1 ili zahtjevu 5, naznačen time da je soj za upotrebu u popravljanju crijevne mikroflore subjekta, za upotrebu u unaprjeđenju zdravlja crijeva subjekta, za upotrebu u unaprjeđenju T regulatornih stanica i tolerancije imuniteta ili je za upotrebu u održavanju homeostaze imuniteta subjekta.
12. Bakterijski soj za upotrebu prema zahtjevu 1 ili zahtjevu 5, naznačen time da je soj za upotrebu u povećavanju apetita subjekta.
13. Bakterijski soj za upotrebu u zahtjevu 1 ili zahtjevu 5, naznačen time da je soj za upotrebu u negativnoj regulaciji izraženosti gena povezanih sa surpresijom apetita, opcionalno naznačeno time da je gen Npy2r ili Cartpt.
14. Bakterijski soj za upotrebu prema zahtjevu 1 ili zahtjevu 5, naznačen time da je soj za upotrebu u povećavanju tjelesne mase subjekta.
15. Bakterijski soj za upotrebu prema bilo kojem od patentnih zahtjeva 1 ili 5 - 14, pri čemu bakterijski soj:
(i) regulira indukciju i/ili izraženost najmanje jednog gena za mobilizaciju ili kemotaksiju, poželjnije pozitivno regulira izraženost gena izabranog od MobA i MobL; ili
(ii) regulira najmanje jedan gen odabran od FlaA1, Fla2, FlaA3, i FlaB; ili
(iii) regulira izraženost barem jednog od sljedećeg: acetil-CoA acetiltransferaza, 3-hidroksiacil-CoA dehidrogenaza, butiril-CoA dehidrogenaza, beta podjedinice elektron-prijenosnog-flavoproteina, alfa podjedinice elektron-prijenosnog-flavoproteina; ili
(iv) negativno regulira izraženost barem jednog gena izabranog od Agt, Cartpt, Cck, Cxcl12 i Gcg; ili
(v) aktivira najmanje jedan gen za imunološki odgovor u debelom crijevu ili ileumu; ili
(vi) aktivira adaptivni imunološki odgovor putem regulacije indukcije i/ili izraženosti gena povezanih sa regulacijom T-stanica; ili
(vii) pozitivno regulira izraženost najmanje jednog gena izabranog od Ly6g6c i Ly6g6e u uzlaznom debelom crijevu; ili
(viii) regulira izraženost najmanje jednog gena koji je izabran od Tlr5, TiR1, Vnn1, Defb37, Pla2g, Muc16, ltln, Sprr1a, Cldn4, Pmp22, Crb3, Magi3, Marveld3, Mpp7, Defcr20, Pcgf2, Ltbp4, Igsf8 i Tcfe2a.
16. Bakterijski soj za upotrebu prema bilo kojem od zahtjeva 1 ili 5-15, naznačen time da je subjekt sisavac, poželjno čovjek.
17. Farmaceutski sastav prema zahtjevu 2, naznačen time da je sastav prilagođen za oralno davanje.
18. Postupak za proizvodnju farmaceutskog sastava prema zahtjevu 2 ili nutritivnog dodatka prema zahtjevu 3, pri čemu spomenuti postupak obuhvaća miješanje bakterijskog soja s farmaceutski prihvatljivom pomoćnom tvari, nosačem ili razrjeđivačem ili nutritivno prihvatljivom pomoćnom tvari, nosačem ili razrjeđivačem.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1117313.5A GB201117313D0 (en) | 2011-10-07 | 2011-10-07 | Bacterium for use in medicine |
| EP16166001.4A EP3097919B1 (en) | 2011-10-07 | 2012-10-08 | Bacterium for use as a probiotic for nutritional and medical applications |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20190761T1 true HRP20190761T1 (hr) | 2019-06-28 |
Family
ID=45035300
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20160843TT HRP20160843T1 (hr) | 2011-10-07 | 2012-10-08 | Bakterija za upotrebu kao probiotik za nutritivne i medicinske primjene |
| HRP20190761TT HRP20190761T1 (hr) | 2011-10-07 | 2019-04-24 | Bakterija za upotrebu kao probiotik za nutritivne i medicinske primjene |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20160843TT HRP20160843T1 (hr) | 2011-10-07 | 2012-10-08 | Bakterija za upotrebu kao probiotik za nutritivne i medicinske primjene |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US9314489B2 (hr) |
| EP (2) | EP3097919B1 (hr) |
| JP (2) | JP6290086B2 (hr) |
| CN (2) | CN108913615A (hr) |
| AU (2) | AU2012320255B2 (hr) |
| BR (1) | BR112014008044A8 (hr) |
| CA (1) | CA2850000C (hr) |
| CY (2) | CY1117900T1 (hr) |
| DK (2) | DK2763685T3 (hr) |
| ES (2) | ES2582932T3 (hr) |
| GB (1) | GB201117313D0 (hr) |
| HR (2) | HRP20160843T1 (hr) |
| HU (2) | HUE043304T2 (hr) |
| LT (1) | LT3097919T (hr) |
| ME (2) | ME03382B (hr) |
| MX (2) | MX350325B (hr) |
| PL (2) | PL3097919T3 (hr) |
| PT (2) | PT3097919T (hr) |
| RS (2) | RS54919B1 (hr) |
| RU (2) | RU2761636C2 (hr) |
| SI (2) | SI2763685T1 (hr) |
| SM (2) | SMT201900283T1 (hr) |
| TR (1) | TR201907488T4 (hr) |
| WO (1) | WO2013050792A1 (hr) |
Families Citing this family (128)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPQ899700A0 (en) | 2000-07-25 | 2000-08-17 | Borody, Thomas Julius | Probiotic recolonisation therapy |
| US9603876B2 (en) | 2008-09-25 | 2017-03-28 | New York University | Compositions and methods for restoring gastrointestinal microbiota following antibiotic treatment |
| US9338515B2 (en) * | 2009-09-03 | 2016-05-10 | At&T Intellectual Property I, L.P. | Real-time and secured picture/video upload via a content delivery network |
| WO2011151941A1 (ja) | 2010-06-04 | 2011-12-08 | 国立大学法人東京大学 | 制御性ｔ細胞の増殖または集積を誘導する作用を有する組成物 |
| US11998479B2 (en) | 2011-02-04 | 2024-06-04 | Seed Health, Inc. | Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure |
| US12279989B2 (en) | 2011-02-04 | 2025-04-22 | Seed Health, Inc. | Method and system for increasing beneficial bacteria and decreasing pathogenic bacteria in the oral cavity |
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