HRP970416A2 - Method for the synthesis of analogs of parathyroid hormone and parathyroid hormone related peptide - Google Patents

Method for the synthesis of analogs of parathyroid hormone and parathyroid hormone related peptide

Info

Publication number: HRP970416A2
Authority: HR; Croatia
Prior art keywords: leu; absent; arg; ala; fragment
Prior art date: 1996-07-30

Application number

HR60/023,322A

Other languages

English (en)

Croatian (hr)

Inventor

Arzeno Humberto

Original Assignee

Arzeno Humberto

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-07-30

Filing date

1997-07-25

Publication date

1998-08-31

1997-07-25 Application filed by Arzeno Humberto filed Critical Arzeno Humberto

1998-08-31 Publication of HRP970416A2 publication Critical patent/HRP970416A2/hr

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
- C07K1/026—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution by fragment condensation in solution
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Endocrinology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Analytical Chemistry (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

HR60/023,322A 1996-07-30 1997-07-25 Method for the synthesis of analogs of parathyroid hormone and parathyroid hormone related peptide HRP970416A2 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US2332296P	1996-07-30	1996-07-30

Publications (1)

Publication Number	Publication Date
HRP970416A2 true HRP970416A2 (en)	1998-08-31

Family

ID=21814418

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR60/023,322A HRP970416A2 (en)	1996-07-30	1997-07-25	Method for the synthesis of analogs of parathyroid hormone and parathyroid hormone related peptide

Country Status (30)

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US (1)	US6849710B1 (de)
EP (1)	EP0822200B1 (de)
JP (1)	JP4229992B2 (de)
KR (1)	KR100518982B1 (de)
CN (1)	CN1293096C (de)
AR (2)	AR008094A1 (de)
AT (1)	ATE277080T1 (de)
AU (1)	AU731160B2 (de)
BR (1)	BR9704138A (de)
CA (1)	CA2206008C (de)
CO (1)	CO4650046A1 (de)
CZ (1)	CZ239697A3 (de)
DE (1)	DE69730787T2 (de)
DK (1)	DK0822200T3 (de)
ES (1)	ES2227639T3 (de)
HR (1)	HRP970416A2 (de)
HU (1)	HUP9701277A3 (de)
IL (1)	IL121391A0 (de)
MA (1)	MA24353A1 (de)
MX (1)	MX9705719A (de)
NO (1)	NO973482L (de)
NZ (1)	NZ328411A (de)
PE (1)	PE91998A1 (de)
PL (1)	PL321391A1 (de)
SG (1)	SG67408A1 (de)
TR (1)	TR199700714A2 (de)
TW (1)	TW505654B (de)
UY (1)	UY24651A1 (de)
YU (1)	YU32197A (de)
ZA (1)	ZA976555B (de)

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CA2628945A1 (en) *	2005-11-10	2007-05-24	Board Of Control Of Michigan Technological University	Black bear parathyroid hormone and methods of using black bear parathyroid hormone
BRPI0706400A2 (pt) *	2006-01-17	2011-03-29	Organon Nv	processos para a hidrólise enzimática seletiva de terc-butil ésteres c-terminais de substratos de peptìdeo, para a sìntese convergente de um peptìdeo de dois ou mais fragmentos de peptìdeo, para a sìntese enzimática por etapas de um peptìdeo na direção do terminal c, e para a sìntese de peptìdeo
US7803770B2 (en) *	2006-10-03	2010-09-28	Radius Health, Inc.	Method of treating osteoporosis comprising administration of PTHrP analog
USRE49444E1 (en)	2006-10-03	2023-03-07	Radius Health, Inc.	Method of treating osteoporosis comprising administration of PTHrP analog
BRPI0719821B8 (pt)	2006-10-03	2021-05-25	Ipsen Pharma Sas	composição estável na armazenagem apropriada para administração a pacientes
WO2010111617A2 (en)	2009-03-27	2010-09-30	Van Andel Research Institute	Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use
BR112012013725A2 (pt)	2009-12-07	2017-01-10	Univ Michigan Tech	paratormônio de urso preto e métodos de usar o paratormônio de uso preto.
CN102731643A (zh) *	2012-06-26	2012-10-17	深圳翰宇药业股份有限公司	一种治疗骨质疏松多肽的制备方法
CN102993293B (zh) *	2012-12-05	2014-05-07	深圳翰宇药业股份有限公司	一种特立帕肽醋酸盐的纯化方法
CA2907454C (en)	2013-03-21	2021-05-04	Sanofi-Aventis Deutschland Gmbh	Synthesis of hydantoin containing peptide products
US10450343B2 (en)	2013-03-21	2019-10-22	Sanofi-Aventis Deutschland Gmbh	Synthesis of cyclic imide containing peptide products
ES3055185T3 (en)	2014-03-28	2026-02-10	Univ Duke	Treatment of an estrogen receptor positive breast cancer using a selective estrogen receptor modulator
CN104530198B (zh) *	2014-12-09	2017-09-15	兰州大学	一种片段缩合制备醋酸去氨加压素的方法
KR20250152679A (ko)	2015-04-29	2025-10-23	래디어스 파마슈티컬스, 인코포레이티드	암을 치료하는 방법
JP7481115B2 (ja)	2017-01-05	2024-05-10	ラジウスファーマシューティカルズ，インコーポレイテッド	Ｒａｄ１９０１－２ｈｃｌの多形性形態
US10996208B2 (en)	2017-04-28	2021-05-04	Radius Health, Inc.	Abaloparatide formulations and methods of testing, storing, modifying, and using same
EP3765488A1 (de) *	2018-03-12	2021-01-20	Fresenius Kabi iPSUM S.r.l.	Verfahren zur herstellung von pthrp-analog
MX2020013713A (es)	2018-07-04	2021-03-02	Radius Pharmaceuticals Inc	Formas polimorficas de rad1901-2hcl.
CN111057139B (zh) *	2018-10-17	2023-12-22	南京华威医药科技集团有限公司	一种制备特立帕肽的新工艺
EP3924328A1 (de)	2019-02-12	2021-12-22	Radius Pharmaceuticals, Inc.	Verfahren und verbindungen

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FR2550204B1 (fr) *	1983-08-05	1987-11-13	Toyo Jozo Kk	Derives peptidiques de (nle8,nle1b, tyr34)-h-pth
AU667662B2 (en) *	1990-07-13	1996-04-04	Regents Of The University Of California, The	Parathyroid hormone analogues modified at positions 3, 6 or 9
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1997
- 1997-07-10 TW TW086109753A patent/TW505654B/zh active
- 1997-07-18 CA CA002206008A patent/CA2206008C/en not_active Expired - Lifetime
- 1997-07-21 PE PE1997000645A patent/PE91998A1/es not_active Application Discontinuation
- 1997-07-23 ZA ZA9706555A patent/ZA976555B/xx unknown
- 1997-07-23 AT AT97112595T patent/ATE277080T1/de active
- 1997-07-23 SG SG1997002618A patent/SG67408A1/en unknown
- 1997-07-23 DE DE69730787T patent/DE69730787T2/de not_active Expired - Lifetime
- 1997-07-23 EP EP97112595A patent/EP0822200B1/de not_active Expired - Lifetime
- 1997-07-23 DK DK97112595T patent/DK0822200T3/da active
- 1997-07-23 HU HU9701277A patent/HUP9701277A3/hu unknown
- 1997-07-23 ES ES97112595T patent/ES2227639T3/es not_active Expired - Lifetime
- 1997-07-24 IL IL12139197A patent/IL121391A0/xx unknown
- 1997-07-24 NZ NZ328411A patent/NZ328411A/xx unknown
- 1997-07-24 JP JP19807297A patent/JP4229992B2/ja not_active Expired - Lifetime
- 1997-07-25 YU YU32197A patent/YU32197A/sh unknown
- 1997-07-25 HR HR60/023,322A patent/HRP970416A2/hr not_active Application Discontinuation
- 1997-07-28 AR ARP970103413A patent/AR008094A1/es not_active Application Discontinuation
- 1997-07-28 CZ CZ972396A patent/CZ239697A3/cs unknown
- 1997-07-28 CO CO97042932A patent/CO4650046A1/es unknown
- 1997-07-29 KR KR1019970035861A patent/KR100518982B1/ko not_active Expired - Lifetime
- 1997-07-29 PL PL97321391A patent/PL321391A1/xx unknown
- 1997-07-29 CN CNB971154686A patent/CN1293096C/zh not_active Expired - Lifetime
- 1997-07-29 MX MX9705719A patent/MX9705719A/es active IP Right Grant
- 1997-07-29 MA MA24742A patent/MA24353A1/fr unknown
- 1997-07-29 NO NO973482A patent/NO973482L/no not_active Application Discontinuation
- 1997-07-29 UY UY24651A patent/UY24651A1/es not_active Application Discontinuation
- 1997-07-29 AU AU32362/97A patent/AU731160B2/en not_active Ceased
- 1997-07-30 TR TR97/00714A patent/TR199700714A2/xx unknown
- 1997-07-30 BR BR9704138A patent/BR9704138A/pt active Search and Examination
- 1997-07-30 US US08/903,124 patent/US6849710B1/en not_active Expired - Lifetime
1999
- 1999-02-16 AR ARP990100625A patent/AR016981A2/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
JP4229992B2 (ja)	2009-02-25
MX9705719A (es)	1998-02-28
PL321391A1 (en)	1998-02-02
ZA976555B (en)	1998-01-30
BR9704138A (pt)	1998-12-29
DK0822200T3 (da)	2005-01-31
TW505654B (en)	2002-10-11
JPH1077295A (ja)	1998-03-24
KR100518982B1 (ko)	2006-05-29
AR016981A2 (es)	2001-08-01
TR199700714A2 (xx)	1998-02-21
CO4650046A1 (es)	1998-09-03
DE69730787T2 (de)	2005-10-13
US6849710B1 (en)	2005-02-01
NO973482L (no)	1998-02-02
ATE277080T1 (de)	2004-10-15
CN1174845A (zh)	1998-03-04
AR008094A1 (es)	1999-12-09
YU32197A (sh)	1999-07-28
AU3236297A (en)	1998-02-05
EP0822200B1 (de)	2004-09-22
KR980009282A (ko)	1998-04-30
EP0822200A1 (de)	1998-02-04
SG67408A1 (en)	1999-09-21
UY24651A1 (es)	2000-12-29
PE91998A1 (es)	1998-12-31
CA2206008A1 (en)	1998-01-30
HU9701277D0 (en)	1997-09-29
CN1293096C (zh)	2007-01-03
CA2206008C (en)	2008-09-23
CZ239697A3 (cs)	1998-04-15
NO973482D0 (no)	1997-07-29
NZ328411A (en)	1998-12-23
HUP9701277A3 (en)	2001-02-28
HUP9701277A2 (hu)	1998-11-30
ES2227639T3 (es)	2005-04-01
DE69730787D1 (de)	2004-10-28
MA24353A1 (fr)	1998-07-01
IL121391A0 (en)	1998-01-04
AU731160B2 (en)	2001-03-22

Legal Events

Date	Code	Title
1998-08-31	A1OB	Publication of a patent application
1999-02-12	AIPI	Request for the grant of a patent on the basis of a substantive examination of a patent application
2005-02-25	ODBC	Application rejected

Publication	Publication Date	Title
HRP970416A2 (en)	1998-08-31	Method for the synthesis of analogs of parathyroid hormone and parathyroid hormone related peptide
US6472505B1 (en)	2002-10-29	Peptide parathyroid hormone analogs
AU723694B2 (en)	2000-08-31	Exendin analogues, processes for their preparation and medicaments containing them
US5229489A (en)	1993-07-20	Parathyroid hormone antagonists
JPH0532696A (ja)	1993-02-09	副甲状腺ホルモン誘導体
CN102171244A (zh)	2011-08-31	糖依赖性胰岛素释放肽的类似物
JP2001500365A (ja)	2001-01-16	Ｐ５３とｍｄｍ２の間の相互作用の阻害剤
JPH06184198A (ja)	1994-07-05	ペプチド類
JP3135122B2 (ja)	2001-02-13	ｈＰＴＨフラグメント（１―３７）とその誘導体
JP5744844B2 (ja)	2015-07-08	副甲状腺ホルモン（ｐｔｈ）受容体アゴニストとしての短鎖ペプチド
JPH0684400B2 (ja)	1994-10-26	新規な生長ホルモン遊離ペプチド
EP0225020A2 (de)	1987-06-10	Peptide, welche in der Sequenz Einheiten von Aminosäureresten 17 bis 24 von VIP enthalten
JPS61210099A (ja)	1986-09-18	新規な成長ホルモン放出性ペプチド
AU736207B2 (en)	2001-07-26	Peptides which promote activation of latent TGF-beta and method of screening TGF-beta activity-regulating compounds
JPWO1998051704A1 (ja)	1999-10-05	潜在型ＴＧＦ−βの活性化を促進するペプチドおよびＴＧＦ−β活性調節化合物のスクリーニング方法
HK1008533A (en)	1999-05-14	Synthesis of analogs of pth and ptrp
MXPA99010560A (en)	2000-09-04	Detergent compositions
JPH08505393A (ja)	1996-06-11	誘導体化カルシトニン
JPWO1995008566A1 (ja)	1996-01-23	新規ペプチド
HK1168863A (en)	2013-01-11	Short-chain peptides as parathyroid hormone (pth) receptor agonist
MXPA99010562A (en)	2001-05-17	Peptide parathyroid hormone analogs
JPH04217997A (ja)	1992-08-07	ペプチド誘導体