ID22753A - Turunan-turunan benzotiofenkarboksamida dan antagonis pgd2 yang mengandung turunan benzotiofenkarboksamida tersebut - Google Patents

Turunan-turunan benzotiofenkarboksamida dan antagonis pgd2 yang mengandung turunan benzotiofenkarboksamida tersebut

Info

Publication number: ID22753A
Authority: ID; Indonesia
Prior art keywords: benzotiofencarcoxamide; benzotiofencarcox; carboxamide; characters; distribution
Prior art date: 1996-12-13

Application number

IDW990472A

Other languages

English (en)

Indonesian (id)

Inventor

Tsunetoshi Honbma

Yoshiharu Hiramatsu

Akinori Arimura

Original Assignee

Shionogi & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-12-13

Filing date

1997-12-10

Publication date

1999-12-09

1997-12-10 Application filed by Shionogi & Co filed Critical Shionogi & Co

1999-12-09 Publication of ID22753A publication Critical patent/ID22753A/id

Links

102100029100 Hematopoietic prostaglandin D synthase Human genes 0.000 title 1
101000988802 Homo sapiens Hematopoietic prostaglandin D synthase Proteins 0.000 title 1
239000005557 antagonist Substances 0.000 title 1
150000003857 carboxamides Chemical class 0.000 title 1
BHMBVRSPMRCCGG-OUTUXVNYSA-N prostaglandin D2 Chemical compound CCCCC[C@H](O)\C=C\[C@@H]1[C@@H](C\C=C/CCCC(O)=O)[C@@H](O)CC1=O BHMBVRSPMRCCGG-OUTUXVNYSA-N 0.000 title 1
BHMBVRSPMRCCGG-UHFFFAOYSA-N prostaglandine D2 Natural products CCCCCC(O)C=CC1C(CC=CCCCC(O)=O)C(O)CC1=O BHMBVRSPMRCCGG-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Pulmonology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Ophthalmology & Optometry (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Indole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IDW990472A 1996-12-13 1997-12-10 Turunan-turunan benzotiofenkarboksamida dan antagonis pgd2 yang mengandung turunan benzotiofenkarboksamida tersebut ID22753A (id)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP33349596		1996-12-13
JP25400197		1997-09-19

Publications (1)

Publication Number	Publication Date
ID22753A true ID22753A (id)	1999-12-09

Family

ID=26541496

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDW990472A ID22753A (id)	1996-12-13	1997-12-10	Turunan-turunan benzotiofenkarboksamida dan antagonis pgd2 yang mengandung turunan benzotiofenkarboksamida tersebut

Country Status (25)

Country	Link
US (1)	US6083974A (cs)
EP (1)	EP0944614B1 (cs)
JP (1)	JP3215441B2 (cs)
KR (1)	KR100433568B1 (cs)
CN (2)	CN1105112C (cs)
AR (1)	AR008939A1 (cs)
AT (1)	ATE223911T1 (cs)
AU (1)	AU718958B2 (cs)
BR (1)	BR9714016A (cs)
CA (1)	CA2274591C (cs)
CZ (1)	CZ297324B6 (cs)
DE (1)	DE69715448T2 (cs)
DK (1)	DK0944614T3 (cs)
ES (1)	ES2181039T3 (cs)
HU (1)	HU226458B1 (cs)
ID (1)	ID22753A (cs)
IL (1)	IL130660A (cs)
NO (1)	NO992838L (cs)
NZ (1)	NZ336143A (cs)
PL (1)	PL191760B1 (cs)
PT (1)	PT944614E (cs)
RU (1)	RU2161617C1 (cs)
TR (1)	TR199901280T2 (cs)
TW (1)	TW438790B (cs)
WO (1)	WO1998025919A1 (cs)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2185380C1 (ru)	1998-03-31	2002-07-20	Сионоги Энд Ко., Лтд.	Способ получения производных бензотиофенкарбоксамида и аминоспиртов (варианты)
ID26346A (id)	1998-03-31	2000-12-14	Shionogi & Co	PROSES PEMBUATAN TURUNAN ASAM 5-HIDROKSIBENZO (b)TIOFEN-3-KARBOKSILAT
ES2241283T3 (es) *	1998-06-03	2005-10-16	SHIONOGI & CO., LTD.	Remedios para el tratamiento del prurito que contienen antagonistas de pgd2.
EP1808427A3 (en) *	1999-07-02	2008-06-25	Shionogi & Co., Ltd.	Novel processes for the preparation of bicyclic aminoalcohols
KR20030010589A (ko)	2000-03-09	2003-02-05	오노 야꾸힝 고교 가부시키가이샤	인돌 유도체, 그 제조 방법 및 용도
ATE311200T1 (de) *	2000-04-12	2005-12-15	Merck Frosst Canada Inc	Verfahren und zusammensetzungen zur behandlung von allergischen zuständen mit pgd2 rezeptor antagonisten
US6410583B1 (en) *	2000-07-25	2002-06-25	Merck Frosst Canada & Co.	Cyclopentanoindoles, compositions containing such compounds and methods of treatment
US7273883B2 (en)	2000-09-14	2007-09-25	Allergan, Inc.	Prostaglandin EP4 antagonist
US7217725B2 (en)	2000-09-14	2007-05-15	Allergan, Inc.	Prostaglandin D2 antagonist
WO2002032892A1 (en) *	2000-10-17	2002-04-25	Shionogi & Co., Ltd	Process for the preparation of pgd2 antagonist
JPWO2002036583A1 (ja) *	2000-11-01	2004-03-11	塩野義製薬株式会社	Ｐｇｄ２受容体拮抗性医薬組成物
AR038136A1 (es)	2002-01-24	2004-12-29	Merck Frosst Canada Inc	Cicloalcanindoles con sustitucion con fluor composiciones que contienen estos compuestos y metodos de tratamiento
CN100378083C (zh)	2002-03-19	2008-04-02	小野药品工业株式会社	羧酸化合物和含有所述化合物作为活性成分的药物制剂
JPWO2004006956A1 (ja) *	2002-07-12	2005-11-10	独立行政法人科学技術振興機構	脳損傷の予後改善薬とそのスクリーニング方法
AU2003242485A1 (en) *	2002-09-30	2004-04-23	Shionogi And Co., Ltd.	Novel uses of prostaglandin d2, prostaglandin d2 agonist and prostaglandin d2 antagonist
EP1558614B1 (en)	2002-10-30	2010-09-01	Merck Frosst Canada Ltd.	Pyridopyrrolizine and pyridoindolizine derivatives
JP4051398B2 (ja)	2004-03-11	2008-02-20	アクテリオンファマシューティカルズリミテッド	テトラヒドロピリドインドール誘導体
JPWO2006068162A1 (ja) *	2004-12-24	2008-06-12	塩野義製薬株式会社	慢性閉塞性肺疾患の治療剤
TW200716093A (en) *	2005-04-28	2007-05-01	Shionogi & Co	An antiasthmatic agent containing PGD2 receptor antagonist and leukotriene receptor antagonist
TWI410410B (zh)	2007-08-10	2013-10-01	Ono Pharmaceutical Co	Phenylacetic acid compounds
CN102822163B (zh)	2009-12-23	2016-01-20	艾恩伍德医药品股份有限公司	Crth2调节剂
US20130178475A1 (en)	2010-03-17	2013-07-11	Ironwood Pharmaceuticals, Inc.	sGC STIMULATORS
TWI532737B (zh)	2010-06-30	2016-05-11	艾諾屋製藥公司	可溶性鳥苷酸環化酶（ｓＧＣ）刺激物
US20130259830A1 (en)	2010-07-12	2013-10-03	Ironwood Pharmaceuticals, Inc.	Crth2 modulators
WO2012009137A1 (en)	2010-07-12	2012-01-19	Ironwood Pharmaceuticals, Inc.	Crth2 modulators
JP5878546B2 (ja)	2010-11-09	2016-03-08	アイアンウッドファーマシューティカルズインコーポレイテッド	ｓＧＣ刺激剤
CA2861804C (en)	2011-12-27	2021-10-26	Ironwood Pharmaceuticals, Inc.	2-benzyl,3(pyrimidin-2-yl)substituted pyrazoles useful as sgc stimulators
WO2014047111A1 (en)	2012-09-18	2014-03-27	Ironwood Pharmaceuticals, Inc.	Sgc stimulators
EP2897953B8 (en)	2012-09-19	2019-06-26	Cyclerion Therapeutics, Inc.	Sgc stimulators
ES2911276T3 (es)	2013-03-15	2022-05-18	Cyclerion Therapeutics Inc	Estimuladores de sGC
JP2016540017A (ja)	2013-12-11	2016-12-22	アイアンウッドファーマシューティカルズインコーポレイテッド	ｓＧＣ刺激物質
WO2015106268A1 (en)	2014-01-13	2015-07-16	Ironwood Pharmaceuticals, Inc.	USE OF sGC STIMULATORS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS
EP3194382B1 (en)	2014-09-17	2021-09-08	Cyclerion Therapeutics, Inc.	Pyrazole derivatives as sgc stimulators
WO2016044445A2 (en)	2014-09-17	2016-03-24	Ironwood Pharmaceuticals, Inc.	sGC STIMULATORS
US10844064B2 (en)	2014-09-17	2020-11-24	Cyclerion Therapeutics, Inc.	sGC stimulators
JP6770522B2 (ja)	2015-02-13	2020-10-14	アンスティチュナショナルドゥラサンテエドゥラルシェルシュメディカル	全身性エリテマトーデスを予防し、及び／又は、治療するためのｐｔｇｄｒ−１及び／又はｐｔｇｄｒ−２アンタゴニスト
KR102513343B1 (ko)	2016-07-07	2023-03-22	사이클리온 테라퓨틱스, 인크.	sGC 자극제의 인 전구약물
EA039753B1 (ru)	2016-07-07	2022-03-10	Сайклерион Терапьютикс, Инк.	ТВЕРДЫЕ ФОРМЫ СТИМУЛЯТОРА sGC

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8406906D0 (en) *	1984-03-16	1984-04-18	Akzo Nv	Benzo-thiazole and benzothiophene derivatives
US4560343A (en) *	1984-06-11	1985-12-24	Honeywell Inc.	Functional check for a hot surface ignitor element
JPS6149A (ja) *	1984-06-12	1986-01-06	Ono Pharmaceut Co Ltd	新規な１３―アザ―１４―オキソ―ＴｘＡ２類似化合物およびそれらを有効成分として含有するトロンボキサン起因疾患治療剤
NZ218115A (en) *	1985-11-18	1990-02-26	Shionogi & Co	Bicyclic sulphonamides and pharmaceutical compositions
CA1294974C (en) *	1987-05-08	1992-01-28	Sanji Hagishita	Bicyclic sulfonamide derivatives and process therefor
US5356926A (en) *	1992-02-24	1994-10-18	Warner-Lambert Company	3-alkyloxy-, aryloxy-, or arylalkyloxy-benzo [β]thiophene-2-carboxamides as inhibitors of cell adhesion
CA2113787A1 (en) *	1993-01-29	1994-07-30	Nobuyuki Hamanaka	Carbocyclic sulfonamides
DE4317076A1 (de) *	1993-05-21	1994-11-24	Bayer Ag	Benzthiophencarbonsäureamid-S-oxide
US5863936A (en) *	1995-04-18	1999-01-26	Geron Corporation	Telomerase inhibitors
PL185107B1 (pl) *	1995-06-21	2003-02-28	Shionogi & Co	Bicykliczne związki aminowe, kompozycja farmaceutyczna i jej stosowanie
JP2001501946A (ja) *	1996-10-08	2001-02-13	イーライ・リリー・アンド・カンパニー	新規セロトニン５―ｈｔ▲下１ｆ▼アゴニスト

1997
- 1997-12-10 BR BR9714016-3A patent/BR9714016A/pt active Search and Examination
- 1997-12-10 AU AU54097/98A patent/AU718958B2/en not_active Ceased
- 1997-12-10 KR KR10-1999-7005154A patent/KR100433568B1/ko not_active Expired - Fee Related
- 1997-12-10 PL PL334072A patent/PL191760B1/pl not_active IP Right Cessation
- 1997-12-10 EP EP97947866A patent/EP0944614B1/en not_active Expired - Lifetime
- 1997-12-10 DK DK97947866T patent/DK0944614T3/da active
- 1997-12-10 NZ NZ336143A patent/NZ336143A/en unknown
- 1997-12-10 HU HU0002869A patent/HU226458B1/hu not_active IP Right Cessation
- 1997-12-10 DE DE69715448T patent/DE69715448T2/de not_active Expired - Lifetime
- 1997-12-10 PT PT97947866T patent/PT944614E/pt unknown
- 1997-12-10 JP JP52649298A patent/JP3215441B2/ja not_active Expired - Fee Related
- 1997-12-10 US US09/308,176 patent/US6083974A/en not_active Expired - Lifetime
- 1997-12-10 ES ES97947866T patent/ES2181039T3/es not_active Expired - Lifetime
- 1997-12-10 CA CA002274591A patent/CA2274591C/en not_active Expired - Fee Related
- 1997-12-10 WO PCT/JP1997/004527 patent/WO1998025919A1/en not_active Ceased
- 1997-12-10 AT AT97947866T patent/ATE223911T1/de not_active IP Right Cessation
- 1997-12-10 IL IL13066097A patent/IL130660A/en not_active IP Right Cessation
- 1997-12-10 CZ CZ0206599A patent/CZ297324B6/cs not_active IP Right Cessation
- 1997-12-10 RU RU99115766/04A patent/RU2161617C1/ru not_active IP Right Cessation
- 1997-12-10 TR TR1999/01280T patent/TR199901280T2/xx unknown
- 1997-12-10 ID IDW990472A patent/ID22753A/id unknown
- 1997-12-10 CN CN97180628A patent/CN1105112C/zh not_active Expired - Fee Related
- 1997-12-11 TW TW086118667A patent/TW438790B/zh not_active IP Right Cessation
- 1997-12-12 AR ARP970105862A patent/AR008939A1/es active IP Right Grant
1999
- 1999-06-10 NO NO992838A patent/NO992838L/no unknown
2002
- 2002-06-11 CN CNB021227608A patent/CN1185226C/zh not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US6083974A (en)	2000-07-04
PL191760B1 (pl)	2006-06-30
HUP0002869A3 (en)	2003-01-28
AU5409798A (en)	1998-07-03
HK1020045A1 (en)	2000-03-10
CN1240438A (zh)	2000-01-05
ATE223911T1 (de)	2002-09-15
KR100433568B1 (ko)	2004-05-31
CA2274591A1 (en)	1998-06-18
AU718958B2 (en)	2000-05-04
KR20000069402A (ko)	2000-11-25
TR199901280T2 (xx)	1999-10-21
DK0944614T3 (da)	2003-01-13
IL130660A0 (en)	2000-06-01
EP0944614A1 (en)	1999-09-29
HUP0002869A2 (hu)	2001-06-28
CZ297324B6 (cs)	2006-11-15
AR008939A1 (es)	2000-02-23
TW438790B (en)	2001-06-07
CN1445225A (zh)	2003-10-01
RU2161617C1 (ru)	2001-01-10
EP0944614B1 (en)	2002-09-11
CN1105112C (zh)	2003-04-09
JP2000514824A (ja)	2000-11-07
DE69715448T2 (de)	2003-08-07
CA2274591C (en)	2005-06-14
NO992838D0 (no)	1999-06-10
HU226458B1 (en)	2008-12-29
PT944614E (pt)	2003-01-31
NZ336143A (en)	2002-05-31
WO1998025919A1 (en)	1998-06-18
JP3215441B2 (ja)	2001-10-09
IL130660A (en)	2002-03-10
PL334072A1 (en)	2000-01-31
NO992838L (no)	1999-07-20
BR9714016A (pt)	2000-02-29
CN1185226C (zh)	2005-01-19
CZ206599A3 (cs)	1999-11-17
ES2181039T3 (es)	2003-02-16
DE69715448D1 (de)	2002-10-17

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ID26099A (id)	2000-11-23	Turunan amida dan antagonis nosiseptin
DE69729805D1 (de)	2004-08-12	Vorrichtung und verfahren von thermischem spritzen mit übertragenem lichtbogen
IL130660A0 (en)	2000-06-01	Benzothiophenecarboxamide derivatives and PGD2 antagonists comprising them
ID24284A (id)	2000-07-13	Produk-produk absorben serta peralatan dan metode untuk memproduksi produk-produk absorben tersebut
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ID21781A (id)	1999-07-22	Benzamidoaldehida baru dan penggunaannya
PL336213A1 (en)	2000-06-05	Gnrh antagonists modified at positions 5 and 6
ID18816A (id)	1998-05-14	Metode dan perangkat injeksi refrigran campuran
ID27544A (id)	2001-04-12	Agonis dan antagonis muskarinat
ID18456A (id)	1998-04-09	Produksi-bersama 6-aminokapronitril dan heksametilenadiamina
ID18682A (id)	1998-04-30	Asiltransferase dan plasma yang mengkodekan asiltransferase
ID18459A (id)	1998-04-09	Produksi-bersama 6-aminokapronitril dan heksametilenadiamina
ID20771A (id)	1999-03-04	Produk yang dibusakan-injeksi dan metode pembuatannya
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