ID30262A - Ligan reseptor melanokortin - Google Patents
Ligan reseptor melanokortinInfo
- Publication number
- ID30262A ID30262A IDW00200102111A ID20012111A ID30262A ID 30262 A ID30262 A ID 30262A ID W00200102111 A IDW00200102111 A ID W00200102111A ID 20012111 A ID20012111 A ID 20012111A ID 30262 A ID30262 A ID 30262A
- Authority
- ID
- Indonesia
- Prior art keywords
- melanokortin
- ligan
- receptor
- ligan receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/68—Melanocyte-stimulating hormone [MSH]
- C07K14/685—Alpha-melanotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/40—Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/68—Melanocyte-stimulating hormone [MSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychology (AREA)
- Pregnancy & Childbirth (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12667399P | 1999-03-29 | 1999-03-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID30262A true ID30262A (id) | 2001-11-15 |
Family
ID=22426131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDW00200102111A ID30262A (id) | 1999-03-29 | 2000-03-21 | Ligan reseptor melanokortin |
Country Status (34)
| Country | Link |
|---|---|
| US (2) | US6613874B1 (fr) |
| EP (1) | EP1165613B1 (fr) |
| JP (1) | JP2002542159A (fr) |
| KR (2) | KR100519201B1 (fr) |
| CN (1) | CN1249086C (fr) |
| AR (1) | AR023201A1 (fr) |
| AT (1) | ATE393783T1 (fr) |
| AU (1) | AU763510B2 (fr) |
| BR (1) | BR0009497A (fr) |
| CA (1) | CA2368431C (fr) |
| CO (1) | CO5170531A1 (fr) |
| CZ (1) | CZ20013407A3 (fr) |
| DE (1) | DE60038734T2 (fr) |
| DK (1) | DK1165613T3 (fr) |
| ES (1) | ES2304345T3 (fr) |
| HK (1) | HK1044954B (fr) |
| HU (1) | HUP0202203A3 (fr) |
| ID (1) | ID30262A (fr) |
| IL (1) | IL145406A0 (fr) |
| MA (1) | MA25403A1 (fr) |
| MX (1) | MXPA01009881A (fr) |
| MY (1) | MY126585A (fr) |
| NO (1) | NO20014568L (fr) |
| NZ (1) | NZ514141A (fr) |
| PE (1) | PE20001641A1 (fr) |
| PL (1) | PL350095A1 (fr) |
| PT (1) | PT1165613E (fr) |
| RU (1) | RU2213098C2 (fr) |
| SA (1) | SA00210192B1 (fr) |
| SK (1) | SK13082001A3 (fr) |
| TR (1) | TR200102765T2 (fr) |
| TW (1) | TWI250990B (fr) |
| WO (1) | WO2000058361A1 (fr) |
| ZA (1) | ZA200107411B (fr) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7192713B1 (en) | 1999-05-18 | 2007-03-20 | President And Fellows Of Harvard College | Stabilized compounds having secondary structure motifs |
| CA2377369A1 (fr) | 1999-06-04 | 2000-12-14 | Merck & Co., Inc. | Piperidines substituees en tant qu'agonistes du recepteur de melanocortine-4 |
| US7235625B2 (en) | 1999-06-29 | 2007-06-26 | Palatin Technologies, Inc. | Multiple agent therapy for sexual dysfunction |
| US6693165B2 (en) | 2000-01-18 | 2004-02-17 | Merck & Co., Inc. | Cyclic peptides as potent and selective melanocortin-4 receptor antagonists |
| PL366630A1 (en) | 2000-08-30 | 2005-02-07 | F.Hoffmann-La Roche Ag | Selective cyclic peptides |
| NZ524190A (en) * | 2000-09-27 | 2004-09-24 | Procter & Gamble | Melanocortin receptor ligands |
| AU2002238106A1 (en) | 2001-02-13 | 2002-08-28 | Palatin Technologies, Inc. | Melanocortin metallopeptides for treatment of sexual dysfunction |
| CA2453515A1 (fr) | 2001-07-11 | 2003-01-23 | Palatin Technologies, Inc. | Peptides lineaires et cycliques specifiques du recepteur de melanocortine |
| US7342089B2 (en) * | 2001-07-11 | 2008-03-11 | Palatin Technologies, Inc. | Cyclic peptides for treatment for cachexia |
| US7345144B2 (en) * | 2001-07-11 | 2008-03-18 | Palatin Technologies, Inc. | Cyclic peptides for treatment of cachexia |
| US20030195187A1 (en) * | 2002-02-04 | 2003-10-16 | Chiron Corporation | Guanidino compounds |
| US7034004B2 (en) * | 2002-05-07 | 2006-04-25 | University Of Florida | Peptides and methods for the control of obesity |
| US7323462B2 (en) | 2002-12-10 | 2008-01-29 | Pfizer Inc. | Morpholine dopamine agonists |
| AU2004251616A1 (en) * | 2003-06-19 | 2005-01-06 | Eli Lilly And Company | Melanocortin receptor 4(MC4) agonists and their uses |
| JP2006527772A (ja) * | 2003-06-19 | 2006-12-07 | イーライ リリー アンド カンパニー | メラノコルチン3受容体(mc3r)作用薬ペプチドの用途 |
| MXPA06003474A (es) * | 2003-09-30 | 2006-06-05 | Novo Nordisk As | Agonistas de receptores de melanocortina. |
| WO2005044839A2 (fr) * | 2003-11-05 | 2005-05-19 | Dana-Farber Cancer Institute, Inc. | Peptides stabilises structures en helice alpha et leurs utilisations |
| AU2015201062B2 (en) * | 2003-11-05 | 2017-03-09 | Dana-Farber Cancer Institute, Inc. | Stabilized alpha helical peptides and uses thereof |
| ES2642214T3 (es) | 2004-01-21 | 2017-11-15 | Novo Nordisk Health Care Ag | Conjugación de péptidos mediante transglutaminasa |
| US6974187B2 (en) * | 2004-01-28 | 2005-12-13 | Tachi-S Co., Ltd. | Vehicle seat structure |
| JP2007530674A (ja) * | 2004-03-29 | 2007-11-01 | イーライ リリー アンド カンパニー | 連続注入によって投与されるメラノコルチン−4受容体(mc4r)アゴニストペプチドの使用 |
| EP1804798A4 (fr) * | 2004-10-05 | 2008-01-23 | Merck & Co Inc | Procedes de traitement d'un abus d'une substance d'une addiction a cette substance |
| WO2006060873A1 (fr) * | 2004-12-09 | 2006-06-15 | Prince Henry's Institute Of Medical Research | Procede de restauration de la fonction reproductrice |
| WO2006073771A2 (fr) * | 2005-01-05 | 2006-07-13 | Eli Lilly And Company | Peptides d'agonistes mc4r ou mc3r lies au polyethyleneglycol |
| WO2006073772A1 (fr) * | 2005-01-05 | 2006-07-13 | Eli Lilly And Company | Peptides agonistes de mc4r ou de mc3r lies a un polyethyleneglycol |
| US20070021433A1 (en) | 2005-06-03 | 2007-01-25 | Jian-Qiang Fan | Pharmacological chaperones for treating obesity |
| US7754691B1 (en) | 2005-07-07 | 2010-07-13 | Palatin Technologies, Inc. | Linear melanocortin receptor-specific peptides for cachexia |
| KR100997177B1 (ko) * | 2005-07-08 | 2010-11-29 | 입센 파마 에스.에이.에스 | 멜라노코르틴 수용체 리간드 |
| AU2006269321A1 (en) * | 2005-07-08 | 2007-01-18 | Ipsen Pharma S.A.S. | Ligands of melanocortin receptors |
| WO2007077112A1 (fr) * | 2005-12-30 | 2007-07-12 | F. Hoffmann-La Roche Ag | Procede de synthese de peptides contenant arginine |
| EP2348016B1 (fr) | 2006-06-09 | 2016-02-17 | SynAct Pharma ApS | Dérivés de phényl pyrrole aminoguanidin |
| US7981998B2 (en) | 2006-12-14 | 2011-07-19 | Aileron Therapeutics, Inc. | Bis-sulfhydryl macrocyclization systems |
| BRPI0720306A2 (pt) * | 2006-12-14 | 2014-02-04 | Aileron Therapeutics Inc | Sistemas de macrociclização da bis-sufidrila |
| PL2118123T3 (pl) | 2007-01-31 | 2016-06-30 | Dana Farber Cancer Inst Inc | Stabilizowane peptydy p53 i ich zastosowania |
| CA2678941C (fr) * | 2007-02-23 | 2018-11-27 | Aileron Therapeutics, Inc. | Systemes macrocycliques de triazole |
| JP5631201B2 (ja) * | 2007-03-28 | 2014-11-26 | プレジデント アンド フェローズ オブ ハーバード カレッジ | ステッチングされたポリペプチド |
| EP2148692B1 (fr) | 2007-05-25 | 2017-01-25 | Ipsen Pharma S.A.S. | Ligands de récepteurs de la mélanocortine modifiés au moyen d'hydantoïne |
| CN104474529A (zh) | 2008-02-08 | 2015-04-01 | 爱勒让治疗公司 | 治疗性的拟肽大环化合物 |
| US20110144303A1 (en) * | 2008-04-08 | 2011-06-16 | Aileron Therapeutics, Inc. | Biologically Active Peptidomimetic Macrocycles |
| WO2009126292A2 (fr) * | 2008-04-08 | 2009-10-15 | Aileron Therapeutics, Inc. | Macrocycles peptidomimétiques biologiquement actifs |
| TW201002340A (en) * | 2008-06-09 | 2010-01-16 | Palatin Technologies Inc | Melanocortin receptor-specific peptides for treatment of obesity |
| WO2009152079A1 (fr) | 2008-06-09 | 2009-12-17 | Palatin Technologies, Inc. | Peptides spécifiques du récepteur de mélanocortine pour le traitement d'un dysfonctionnement sexuel |
| US20110144306A1 (en) * | 2008-07-23 | 2011-06-16 | President And Fellows Of Harvard College | Ligation of stapled polypeptides |
| CN104961795A (zh) | 2008-09-22 | 2015-10-07 | 爱勒让治疗公司 | 用于制备纯化的多肽组合物的方法 |
| AU2010204648B2 (en) | 2009-01-14 | 2016-09-01 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| EP2440572B1 (fr) | 2009-06-08 | 2017-04-05 | Palatin Technologies, Inc. | Peptides spécifiques des récepteurs aux mélanocortines à pont lactame |
| EA020959B1 (ru) | 2009-06-08 | 2015-03-31 | Палатин Текнолоджиз, Инк. | Пептиды, специфичные к меланокортиновым рецепторам |
| UY32690A (es) | 2009-06-08 | 2011-01-31 | Astrazeneca Ab | Péptidos específicos para receptores de melanocortina |
| BR112012000867A2 (pt) | 2009-07-13 | 2019-09-24 | Harvard College | "polipeptídeos bifuncional costurado e uso do mesmo" |
| JP2013505300A (ja) | 2009-09-22 | 2013-02-14 | エルロン・セラピューティクス・インコーポレイテッド | ペプチド模倣大環状分子 |
| JP2013510881A (ja) * | 2009-11-16 | 2013-03-28 | イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ | Ac−Arg−シクロ(Cys−D−Ala−His−D−Phe−Arg−Trp−Cys)−NH2の合成のための方法 |
| EA021897B1 (ru) | 2009-11-23 | 2015-09-30 | Палатин Текнолоджиз, Инк. | Циклические пептиды, специфичные к рецептору меланокортина-1 |
| BR112012011780A2 (pt) | 2009-11-23 | 2019-09-24 | Palatin Technologies, Inc | peptídeo linear,composição farmacêutica,métodopara tratamento de umadoença,indicação,condição ou sídrome mediadsa por receptor de melanocortina emum mamífero humano ou não humano e método para tratamento de uma condição responsiva ás alterações em função de receptor de melanocortina em um mamifero humano ou não humano |
| CN101824415A (zh) * | 2010-03-31 | 2010-09-08 | 华东师范大学 | 黑素皮质1型受体基因的snp及其应用 |
| KR102104762B1 (ko) | 2010-08-13 | 2020-04-24 | 에일러론 테라퓨틱스 인코포레이티드 | 펩티도미메틱 거대고리 |
| WO2012040459A2 (fr) | 2010-09-22 | 2012-03-29 | President And Fellows Of Harvard College | Peptides de ciblage de la béta-caténine et leurs utilisations |
| WO2012100342A1 (fr) | 2011-01-27 | 2012-08-02 | Université de Montréal | Pyrazolopyridine et dérivés de pyrazolopyrimidine en tant que modulateurs du récepteur de la mélanocortine-4 |
| WO2012174423A1 (fr) | 2011-06-17 | 2012-12-20 | President And Fellows Of Harvard College | Polypeptides stabilisés comme régulateurs de fonction gtpase rab |
| EP2768518A4 (fr) | 2011-10-18 | 2015-05-27 | Aileron Therapeutics Inc | Macrocycles peptidomimétiques |
| RU2642299C2 (ru) | 2012-02-15 | 2018-01-24 | Эйлерон Терапьютикс, Инк. | P53 пептидомиметические макроциклы |
| CA2864120A1 (fr) | 2012-02-15 | 2013-08-22 | Aileron Therapeutics, Inc. | Macrocycles peptidomimetiques reticules par triazole et par thioether |
| RS61957B1 (sr) | 2012-09-26 | 2021-07-30 | Harvard College | Uvezani peptidi blokirani prolinom i njihove upotrebe |
| BR112015009470A2 (pt) | 2012-11-01 | 2019-12-17 | Aileron Therapeutics Inc | aminoácidos dissubstituídos e seus métodos de preparação e uso |
| KR20150131244A (ko) | 2013-03-13 | 2015-11-24 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 스테이플드 및 스티치드 폴리펩티드 및 그의 용도 |
| BR112015031277A2 (pt) | 2013-06-14 | 2017-09-19 | Harvard College | Moduladores do receptor de insulina de polipeptídeos estabilizados, análogos de insulina, composições farmacêuticas compreendendo os referidos polipeptídeos e métodos de preparação e usos dos mesmos |
| EP3145523A4 (fr) | 2014-05-21 | 2018-02-21 | President and Fellows of Harvard College | Peptides inhibiteurs de ras et leurs utilisations |
| CN107106642B (zh) | 2014-09-24 | 2021-02-26 | 艾瑞朗医疗公司 | 拟肽大环化合物及其制剂 |
| EP3197478A4 (fr) | 2014-09-24 | 2018-05-30 | Aileron Therapeutics, Inc. | Macrocycles peptidomimétiques et leurs utilisations |
| JP2018516844A (ja) | 2015-03-20 | 2018-06-28 | エルロン・セラピューティクス・インコーポレイテッドAileron Therapeutics,Inc. | ペプチド模倣大環状分子およびその使用 |
| US10059741B2 (en) | 2015-07-01 | 2018-08-28 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| EP3347372A4 (fr) | 2015-09-10 | 2019-09-04 | Aileron Therapeutics, Inc. | Macrocycles peptidomimétiques en tant que modulateurs de mcl-1 |
| PT3773558T (pt) | 2019-05-10 | 2022-09-13 | Synact Pharma Aps | Tratamento combinado de doença artrítica |
| CN110681362B (zh) * | 2019-09-26 | 2020-09-11 | 浙江大学 | 以羧基和吲哚基为功能基团的混合模式层析介质 |
| US11590209B2 (en) | 2020-01-21 | 2023-02-28 | Palatin Technologies, Inc. | Use of bremelanotide in patients with controlled hypertension |
| US11932628B2 (en) | 2021-01-04 | 2024-03-19 | Regents Of The University Of Minnesota | Selective small molecule peptidomimetic melanocortin ligands |
| AU2022296767A1 (en) | 2021-06-21 | 2024-02-01 | Synact Pharma Aps | Phenyl pyrrole aminoguanidine salts and formulations |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5462927A (en) | 1985-04-30 | 1995-10-31 | The Administrators Of The Tulane Educational Fund | Peptides aiding nerve regeneration |
| ATE109793T1 (de) | 1987-05-22 | 1994-08-15 | University Patents Inc | Lineare und zyklische analoge von alpha-msh- fragmenten mit ausserordentlicher wirkung. |
| WO1989002897A1 (fr) | 1987-09-24 | 1989-04-06 | The Administrators Of The Tulane Educational Fund | Peptides a usage therapeutique |
| ZA908610B (en) | 1989-11-03 | 1991-08-28 | Univ Tulane | Peptides aiding nerve regeneration |
| ES2089256T3 (es) | 1991-02-15 | 1996-10-01 | Takeda Chemical Industries Ltd | Antagonista de la endotelina. |
| ATE155486T1 (de) | 1991-08-13 | 1997-08-15 | Takeda Chemical Industries Ltd | Zyklische peptide und ihre verwendung |
| RU2096415C1 (ru) * | 1991-09-30 | 1997-11-20 | Дзе Дюпон Мерк Фармасьютикал Компани | Циклические пептиды или их фармацевтически приемлемые соли, фармацевтическая композиция |
| EP0552417B1 (fr) | 1991-11-19 | 1999-07-07 | Takeda Chemical Industries, Ltd. | Peptides cycliques et leurs utilisations |
| EP0547317A1 (fr) | 1991-12-19 | 1993-06-23 | Takeda Chemical Industries, Ltd. | Antagonistes d'endothéline |
| DE9203901U1 (de) | 1992-03-24 | 1992-07-16 | Croon & Lucke Maschinenfabrik Gmbh, 7947 Mengen | Gestell zum Lagern von flächigen Werkstücken |
| DE69330868T2 (de) | 1992-07-27 | 2002-04-25 | Biomeasure, Inc. | Antagonisten des neuromedin b rezeptors |
| US5569741A (en) | 1992-07-27 | 1996-10-29 | Biomeasure, Inc. | Cyclic octapeptide neuromedin B receptor antagonists |
| AU673731B2 (en) | 1993-06-03 | 1996-11-21 | Banyu Pharmaceutical Co., Ltd. | Novel endothelin antagonistic peptide |
| EP0714909A1 (fr) | 1994-12-01 | 1996-06-05 | Takeda Chemical Industries, Ltd. | Composition pour la prévention et le traitement de maladies de la circulation pulmonaire |
| US6054556A (en) * | 1995-04-10 | 2000-04-25 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Melanocortin receptor antagonists and agonists |
| US5731408A (en) * | 1995-04-10 | 1998-03-24 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Peptides having potent antagonist and agonist bioactivities at melanocortin receptors |
| AU5514396A (en) | 1995-04-28 | 1996-11-18 | Takeda Chemical Industries Ltd. | Cyclic pentapeptide lh-rh receptor antagonists |
| US5817750A (en) | 1995-08-28 | 1998-10-06 | La Jolla Cancer Research Foundation | Structural mimics of RGD-binding sites |
| DE69719320T2 (de) | 1996-06-11 | 2003-12-11 | Novartis Ag, Basel | Kombination eines somatostatin analogs und eines rapamycins |
| WO1997049724A1 (fr) | 1996-06-25 | 1997-12-31 | Nisshin Flour Milling Co., Ltd. | Depsipeptides cycliques et medicaments contenant ces composes comme ingredient actif |
| US6251861B1 (en) | 1996-06-27 | 2001-06-26 | Takeda Chemical Industries, Ltd. | Treatment of cerebral infarction using cyclic hexapeptides |
| US5770380A (en) | 1996-09-13 | 1998-06-23 | University Of Pittsburgh | Synthetic antibody mimics--multiple peptide loops attached to a molecular scaffold |
| IT1288388B1 (it) | 1996-11-19 | 1998-09-22 | Angeletti P Ist Richerche Bio | Uso di sostanze che attivano il recettore del cntf ( fattore neurotrofico ciliare) per la preparazione di farmaci per la terapia |
| WO1998027113A2 (fr) | 1996-12-17 | 1998-06-25 | Quadrant Holdings Cambridge Limited | Melanocortines |
| SE9700620D0 (sv) * | 1997-02-21 | 1997-02-21 | Wapharm Ab | Cykliska peptider med selektivitet för MSH-receptor subtyper |
| GB9827500D0 (en) | 1998-12-14 | 1999-02-10 | Wapharm Ab | Compounds for control of eating, growth and body weight |
-
2000
- 2000-03-21 DK DK00919500T patent/DK1165613T3/da active
- 2000-03-21 PT PT00919500T patent/PT1165613E/pt unknown
- 2000-03-21 IL IL14540600A patent/IL145406A0/xx unknown
- 2000-03-21 KR KR10-2001-7012436A patent/KR100519201B1/ko not_active Expired - Fee Related
- 2000-03-21 HU HU0202203A patent/HUP0202203A3/hu unknown
- 2000-03-21 MX MXPA01009881A patent/MXPA01009881A/es active IP Right Grant
- 2000-03-21 EP EP00919500A patent/EP1165613B1/fr not_active Expired - Lifetime
- 2000-03-21 CA CA002368431A patent/CA2368431C/fr not_active Expired - Fee Related
- 2000-03-21 DE DE60038734T patent/DE60038734T2/de not_active Expired - Fee Related
- 2000-03-21 PL PL00350095A patent/PL350095A1/xx not_active Application Discontinuation
- 2000-03-21 WO PCT/US2000/007473 patent/WO2000058361A1/fr not_active Ceased
- 2000-03-21 AU AU40179/00A patent/AU763510B2/en not_active Ceased
- 2000-03-21 SK SK1308-2001A patent/SK13082001A3/sk unknown
- 2000-03-21 TR TR2001/02765T patent/TR200102765T2/xx unknown
- 2000-03-21 AT AT00919500T patent/ATE393783T1/de not_active IP Right Cessation
- 2000-03-21 RU RU2001128890/04A patent/RU2213098C2/ru not_active IP Right Cessation
- 2000-03-21 JP JP2000608653A patent/JP2002542159A/ja active Pending
- 2000-03-21 KR KR1020047019303A patent/KR100558131B1/ko not_active Expired - Fee Related
- 2000-03-21 ES ES00919500T patent/ES2304345T3/es not_active Expired - Lifetime
- 2000-03-21 BR BR0009497-8A patent/BR0009497A/pt not_active IP Right Cessation
- 2000-03-21 NZ NZ514141A patent/NZ514141A/xx unknown
- 2000-03-21 HK HK02104687.8A patent/HK1044954B/en not_active IP Right Cessation
- 2000-03-21 CN CNB008057540A patent/CN1249086C/zh not_active Expired - Fee Related
- 2000-03-21 ID IDW00200102111A patent/ID30262A/id unknown
- 2000-03-21 CZ CZ20013407A patent/CZ20013407A3/cs unknown
- 2000-03-27 MY MYPI20001220A patent/MY126585A/en unknown
- 2000-03-28 CO CO00022068A patent/CO5170531A1/es not_active Application Discontinuation
- 2000-03-28 TW TW089105726A patent/TWI250990B/zh not_active IP Right Cessation
- 2000-03-29 PE PE2000000267A patent/PE20001641A1/es not_active Application Discontinuation
- 2000-03-29 US US09/537,789 patent/US6613874B1/en not_active Expired - Fee Related
- 2000-03-29 AR ARP000101405A patent/AR023201A1/es active IP Right Grant
- 2000-06-26 SA SA00210192A patent/SA00210192B1/ar unknown
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2001
- 2001-09-07 ZA ZA200107411A patent/ZA200107411B/xx unknown
- 2001-09-20 NO NO20014568A patent/NO20014568L/no not_active Application Discontinuation
- 2001-09-26 MA MA26340A patent/MA25403A1/fr unknown
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2003
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