IL103452A - Isolated peptide of a dermatophagoides protein allergen comprising at least one t-cell epitope of the protein allergen - Google Patents

Isolated peptide of a dermatophagoides protein allergen comprising at least one t-cell epitope of the protein allergen

Info

Publication number
IL103452A
IL103452A IL10345292A IL10345292A IL103452A IL 103452 A IL103452 A IL 103452A IL 10345292 A IL10345292 A IL 10345292A IL 10345292 A IL10345292 A IL 10345292A IL 103452 A IL103452 A IL 103452A
Authority
IL
Israel
Prior art keywords
seq
peptide
amino acid
per
ala
Prior art date
Application number
IL10345292A
Other languages
English (en)
Other versions
IL103452A0 (en
Original Assignee
Immulogic Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immulogic Pharma Corp filed Critical Immulogic Pharma Corp
Publication of IL103452A0 publication Critical patent/IL103452A0/xx
Publication of IL103452A publication Critical patent/IL103452A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43531—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from mites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Insects & Arthropods (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Housing For Livestock And Birds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL10345292A 1991-10-16 1992-10-16 Isolated peptide of a dermatophagoides protein allergen comprising at least one t-cell epitope of the protein allergen IL103452A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77785991A 1991-10-16 1991-10-16
US88139692A 1992-05-08 1992-05-08

Publications (2)

Publication Number Publication Date
IL103452A0 IL103452A0 (en) 1993-03-15
IL103452A true IL103452A (en) 2004-07-25

Family

ID=27119374

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10345292A IL103452A (en) 1991-10-16 1992-10-16 Isolated peptide of a dermatophagoides protein allergen comprising at least one t-cell epitope of the protein allergen

Country Status (15)

Country Link
EP (1) EP0623168B1 (de)
JP (2) JPH07502890A (de)
KR (1) KR100260342B1 (de)
AT (1) ATE444360T1 (de)
AU (1) AU676668B2 (de)
DE (1) DE69233772D1 (de)
ES (1) ES2334179T3 (de)
FI (1) FI110385B (de)
HU (1) HU220462B1 (de)
IL (1) IL103452A (de)
MX (1) MX9205985A (de)
NO (1) NO314586B1 (de)
NZ (1) NZ244772A (de)
PT (1) PT100979B (de)
WO (1) WO1993008279A1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5433948A (en) * 1990-02-13 1995-07-18 Thomas; Wayne R. Cloning and sequencing of allergens of dermatophagoides (house dust mite)
WO1994024281A1 (en) * 1993-04-14 1994-10-27 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from dermatophagoides (house dust mite)
WO1994004572A1 (fr) * 1992-08-14 1994-03-03 Torii & Co., Ltd. Peptide allergene
AU674584B2 (en) * 1993-06-02 1997-01-02 Tvw Telethon Institute For Child Health Research Cryptic peptides for use in inducing immunologic tolerance
AU7195194A (en) * 1993-07-16 1995-02-13 Meiji Milk Products Co., Ltd. Antiallergic agent
US6180771B1 (en) 1993-12-08 2001-01-30 Immulogic Pharmaceutical Corp. Nucleic acids encoding a house dust mite allergen, Der p III, and uses therefor
KR100733887B1 (ko) * 1993-12-08 2007-12-20 헤스카 코포레이션 DerpⅢ단백질알레르겐을암호화하는분리된핵산
AU1201595A (en) * 1993-12-22 1995-07-10 Asahi Breweries, Ltd. Novel recombinant deri allergenic substance, precursor thereof, and process for producing them
JPH07215996A (ja) * 1994-01-31 1995-08-15 Torii Yakuhin Kk ダニアレルゲンのｂ細胞エピトープ
ES2285703T3 (es) * 1994-04-14 2007-11-16 Merck Patent Gmbh Formulaciones farmaceuticas de peptidos para el tratamiento de alergia a los acaros del polvo.
SE9403526D0 (sv) 1994-10-14 1994-10-14 Astra Ab New Peptides
SE9501067D0 (sv) 1995-03-24 1995-03-24 Astra Ab New peptides
WO1997035193A1 (en) 1996-03-21 1997-09-25 Imperial College Of Science, Technology And Medicine Cryptic peptides and method for their identification
WO1998020902A1 (en) * 1996-11-13 1998-05-22 Meiji Milk Products Co., Ltd. Peptide immunotherapeutic agent
AR020102A1 (es) * 1998-07-30 2002-04-10 Ucb Sa Compuesto para la prevencion y/o tratamiento de la alergia; composicion farmaceutica, composicion cosmetica, composicion en forma de bebida, alimento y/oalimento para animales domesticos que lo comprende y uso de dicho compuesto o dicha composicion farmaceutica para la fabricacion de un alimento
GB0006437D0 (en) 2000-03-17 2000-05-10 Leuven Res & Dev Vzw Compounds for the modulation of allergen sensitivity by antigens sharing T cell epitopes with allergens
FR2809413B1 (fr) * 2000-05-29 2004-10-22 Tabacs & Allumettes Ind Production d'allergenes recombinants dans des cellules vegetales
GB0108752D0 (en) * 2001-04-06 2001-05-30 Isis Innovation Peptide epitopes and uses thereof
JP5750600B2 (ja) 2006-08-11 2015-07-22 ライフ・サイエンシーズ・リサーチ・パートナーズ・フェレニゲング・ゾンデル・ウィンストーメルクＬｉｆｅ Ｓｃｉｅｎｃｅｓ Ｒｅｓｅａｒｃｈ Ｐａｒｔｎｅｒｓ Ｖｚｗ 免疫原性ペプチドおよび免疫障害におけるその使用
GB0710529D0 (en) 2007-06-01 2007-07-11 Circassia Ltd Vaccine
DK2083856T3 (da) 2007-08-15 2011-01-24 Circassia Ltd Peptider til desensibilisering mod allergener
AU2009214041A1 (en) 2008-02-14 2009-08-20 Katholieke Universiteit Leuven CD4+ T-cells with cytolytic properties
EP2719396B1 (de) 2008-02-14 2017-06-21 Life Sciences Research Partners VZW Auf intrazelluläre Pathogene abzielende Immuntherapie
CA2715488C (en) 2008-02-14 2019-09-24 Life Sciences Research Partners Vzw Immunogenic control of tumours and tumour cells
EP2252329B1 (de) 2008-02-14 2015-06-17 Life Sciences Research Partners VZW Beseitigung von immunreaktionen gegen virale vektoren
WO2010018384A1 (en) * 2008-08-15 2010-02-18 Circassia Limited T-cell antigen peptide from allergen for stimulation of il-10 production
GB0821806D0 (en) 2008-11-28 2009-01-07 Circassia Ltd Compositions with reduced dimer formation
WO2012069568A2 (en) 2010-11-25 2012-05-31 Imnate Sarl Immunogenic peptides for use in the prevention and/or treatment of infectious diseases, autoimmune diseases, immune responses to allofactors, allergic diseases, tumors, graft rejection and immune responses against viral vectors used for gene therapy or gene vaccination
GB201201511D0 (en) 2012-01-30 2012-03-14 Univ Leuven Kath Modified epitopes for boosting CD4+ T-cell responses
GB201309469D0 (en) 2013-05-28 2013-07-10 Imcyse Sa Detection of CD4+ T lymphocytes
HK1223019A1 (zh) * 2013-06-06 2017-07-21 Anergis Sa 用於治疗室内尘蟎过敏的连续重叠肽
US10729791B2 (en) 2015-05-18 2020-08-04 Imcyse Sa Animal models for evaluating pharmaceutical compounds
ES2874077T3 (es) 2015-09-25 2021-11-04 Imcyse Sa Métodos y compuestos mejorados para eliminar respuestas inmunitarias a agentes terapéuticos
SG11201808710UA (en) 2016-04-19 2018-11-29 Imcyse Sa Novel immunogenic cd1d binding peptides
JP7078620B2 (ja) * 2016-11-16 2022-05-31 イミュノミック セラピューティックス， インコーポレイテッド アレルギーの治療のための核酸
KR102010436B1 (ko) * 2018-02-28 2019-08-13 을지대학교 산학협력단 신규 알러지 반응 검사용 조성물
GB202409214D0 (en) * 2024-06-26 2024-08-07 Univ Birmingham tolerogenic peptides

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4234569A (en) * 1978-10-04 1980-11-18 The Johns Hopkins University Production of aldehyde-treated allergen-containing substances
JP2993967B2 (ja) * 1987-06-17 1999-12-27 インスティテュート・フォー・チャイルド・ヘルス・リサーチ ダニアレルゲンのクローニング
FR2650181B1 (fr) * 1989-07-27 1993-12-03 Laboratoire Stallergenes Procede pour combiner un melange de substances heterogenes a des liposomes
ES2174822T3 (es) * 1989-11-03 2002-11-16 Immulogic Pharma Corp Una proteina felina reactiva con celulas t humanas (trfp) aislada de polvo domestico y usos para la misma.
JP2596466B2 (ja) * 1990-03-03 1997-04-02 アサヒビール株式会社 ダニの主要アレルゲンの還伝情報を有するｄｎａおよび該アレルゲンの製造方法
KR100274321B1 (ko) * 1990-09-11 2000-12-15 스미드 이. 그레이엄 데르마토파고이디즈(집 먼지 진드기)의 알레르기 항원의 클로닝 및 서열결정

Also Published As

Publication number Publication date
HU220462B1 (hu) 2002-02-28
IL103452A0 (en) 1993-03-15
EP0623168A1 (de) 1994-11-09
HUT71211A (en) 1995-11-28
PT100979A (pt) 1994-01-31
NO314586B1 (no) 2003-04-14
FI941757L (fi) 1994-06-16
NZ244772A (en) 1995-09-26
AU676668B2 (en) 1997-03-20
NO941371L (no) 1994-06-15
NO941371D0 (no) 1994-04-15
FI941757A0 (fi) 1994-04-15
PT100979B (pt) 1999-08-31
AU2865492A (en) 1993-05-21
EP0623168B1 (de) 2009-09-30
MX9205985A (es) 1993-08-01
FI110385B (fi) 2003-01-15
KR940702936A (ko) 1994-09-17
JP2009005709A (ja) 2009-01-15
HU9401108D0 (en) 1994-08-29
KR100260342B1 (ko) 2000-07-01
ATE444360T1 (de) 2009-10-15
WO1993008279A1 (en) 1993-04-29
JPH07502890A (ja) 1995-03-30
ES2334179T3 (es) 2010-03-05
DE69233772D1 (de) 2009-11-12

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