PT100979A - Epitopos de celula t dos alergenos principais de dermatophagoides (acaro do po domestico), peptidos modificados, sequencias de acidos nucleicos que os codificam, composicoes farmaceuticas que os contem e seu uso - Google Patents

Epitopos de celula t dos alergenos principais de dermatophagoides (acaro do po domestico), peptidos modificados, sequencias de acidos nucleicos que os codificam, composicoes farmaceuticas que os contem e seu uso

Info

Publication number: PT100979A
Authority: PT; Portugal
Prior art keywords: peptides; der; cell; dermatophagoides; epithopes
Prior art date: 1991-10-16

Application number

PT100979A

Other languages

English (en)

Other versions

PT100979B (pt

Inventor

Bruce L Rogers

Richard D Garman

Julia L Greenstein

Mei-Chang Kuo

Original Assignee

Immulogic Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-10-16

Filing date

1992-10-16

Publication date

1994-01-31

1992-10-16 Application filed by Immulogic Pharma Corp filed Critical Immulogic Pharma Corp

1994-01-31 Publication of PT100979A publication Critical patent/PT100979A/pt

1999-08-31 Publication of PT100979B publication Critical patent/PT100979B/pt

Links

239000013566 allergen Substances 0.000 title abstract 5
241000238710 Dermatophagoides Species 0.000 title abstract 2
108091005601 modified peptides Proteins 0.000 title abstract 2
150000007523 nucleic acids Chemical class 0.000 title abstract 2
102000039446 nucleic acids Human genes 0.000 title 1
108020004707 nucleic acids Proteins 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 4
108090000765 processed proteins & peptides Proteins 0.000 abstract 4
210000001744 T-lymphocyte Anatomy 0.000 abstract 2
229960004784 allergens Drugs 0.000 abstract 2
108090000623 proteins and genes Proteins 0.000 abstract 2
102000004169 proteins and genes Human genes 0.000 abstract 2
230000001225 therapeutic effect Effects 0.000 abstract 2
108010055622 Dermatophagoides farinae antigen f 1 Proteins 0.000 abstract 1
108010061629 Dermatophagoides pteronyssinus antigen p 1 Proteins 0.000 abstract 1
108010061608 Dermatophagoides pteronyssinus antigen p 2 Proteins 0.000 abstract 1
241000238711 Pyroglyphidae Species 0.000 abstract 1
238000003745 diagnosis Methods 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
229940046533 house dust mites Drugs 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
230000035945 sensitivity Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43531—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from mites
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Zoology (AREA)
General Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Medicinal Chemistry (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Insects & Arthropods (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Tropical Medicine & Parasitology (AREA)
Gastroenterology & Hepatology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Toxicology (AREA)
Microbiology (AREA)
Pulmonology (AREA)
Peptides Or Proteins (AREA)
Housing For Livestock And Birds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

PT100979A 1991-10-16 1992-10-16 Epitopos de celula t dos alergenos principais de dermatophagoides (acaro do po domestico), peptidos modificados, sequencias de acidos nucleicos que os codificam, composicoes farmaceuticas que os contem e seu uso PT100979B (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US77785991A	1991-10-16	1991-10-16
US88139692A	1992-05-08	1992-05-08

Publications (2)

Publication Number	Publication Date
PT100979A true PT100979A (pt)	1994-01-31
PT100979B PT100979B (pt)	1999-08-31

Family

ID=27119374

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT100979A PT100979B (pt)	1991-10-16	1992-10-16	Epitopos de celula t dos alergenos principais de dermatophagoides (acaro do po domestico), peptidos modificados, sequencias de acidos nucleicos que os codificam, composicoes farmaceuticas que os contem e seu uso

Country Status (15)

Country	Link
EP (1)	EP0623168B1 (pt)
JP (2)	JPH07502890A (pt)
KR (1)	KR100260342B1 (pt)
AT (1)	ATE444360T1 (pt)
AU (1)	AU676668B2 (pt)
DE (1)	DE69233772D1 (pt)
ES (1)	ES2334179T3 (pt)
FI (1)	FI110385B (pt)
HU (1)	HU220462B1 (pt)
IL (1)	IL103452A (pt)
MX (1)	MX9205985A (pt)
NO (1)	NO314586B1 (pt)
NZ (1)	NZ244772A (pt)
PT (1)	PT100979B (pt)
WO (1)	WO1993008279A1 (pt)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5433948A (en) *	1990-02-13	1995-07-18	Thomas; Wayne R.	Cloning and sequencing of allergens of dermatophagoides (house dust mite)
WO1994024281A1 (en) *	1993-04-14	1994-10-27	Immulogic Pharmaceutical Corporation	T cell epitopes of the major allergens from dermatophagoides (house dust mite)
AU664920B2 (en) *	1992-08-14	1995-12-07	Asahi Breweries, Ltd.	Peptide having allergenicity
EP0705108A4 (en) *	1993-06-02	1997-08-06	Tvw Telethon Inst Child Health	USE OF CRYPTIC PEPTIDES FOR INDUCTION IMMUNOLOGICAL TOLERANCE
AU7195194A (en) *	1993-07-16	1995-02-13	Meiji Milk Products Co., Ltd.	Antiallergic agent
US6180771B1 (en)	1993-12-08	2001-01-30	Immulogic Pharmaceutical Corp.	Nucleic acids encoding a house dust mite allergen, Der p III, and uses therefor
KR100733887B1 (ko) *	1993-12-08	2007-12-20	헤스카 코포레이션	DerpⅢ단백질알레르겐을암호화하는분리된핵산
JP3520089B2 (ja) *	1993-12-22	2004-04-19	アサヒビール株式会社	新規な組換えＤｅｒｌアレルゲン物質、そのプロ体及びこれらの産生方法
JPH07215996A (ja) *	1994-01-31	1995-08-15	Torii Yakuhin Kk	ダニアレルゲンのｂ細胞エピトープ
DK0755407T3 (da) *	1994-04-14	2007-08-06	Merck Patent Gmbh	Farmaceutisk peptidformuleringer til behandling af stövmideallergi
SE9403526D0 (sv)	1994-10-14	1994-10-14	Astra Ab	New Peptides
SE9501067D0 (sv)	1995-03-24	1995-03-24	Astra Ab	New peptides
US6737406B1 (en)	1996-03-21	2004-05-18	Circassia, Ltd.	Cryptic peptides and method for their identification
JP4218987B2 (ja)	1996-11-13	2009-02-04	明治乳業株式会社	ペプチド免疫療法治療剤
AR020102A1 (es)	1998-07-30	2002-04-10	Ucb Sa	Compuesto para la prevencion y/o tratamiento de la alergia; composicion farmaceutica, composicion cosmetica, composicion en forma de bebida, alimento y/oalimento para animales domesticos que lo comprende y uso de dicho compuesto o dicha composicion farmaceutica para la fabricacion de un alimento
GB0006437D0 (en)	2000-03-17	2000-05-10	Leuven Res & Dev Vzw	Compounds for the modulation of allergen sensitivity by antigens sharing T cell epitopes with allergens
FR2809413B1 (fr) *	2000-05-29	2004-10-22	Tabacs & Allumettes Ind	Production d'allergenes recombinants dans des cellules vegetales
GB0108752D0 (en) *	2001-04-06	2001-05-30	Isis Innovation	Peptide epitopes and uses thereof
ES2709176T3 (es)	2006-08-11	2019-04-15	Life Sciences Res Partners Vzw	Péptidos inmunogénicos y su uso en trastornos inmunitarios
GB0710529D0 (en)	2007-06-01	2007-07-11	Circassia Ltd	Vaccine
NZ583362A (en) *	2007-08-15	2012-06-29	Circassia Ltd	Peptide with reduced dimer formation
EP2252329B1 (en)	2008-02-14	2015-06-17	Life Sciences Research Partners VZW	Elimination of immune responses to viral vectors
EP2626081B1 (en)	2008-02-14	2017-03-22	Life Sciences Research Partners VZW	Immunogenic control of tumours and tumour cells
ES2637812T3 (es)	2008-02-14	2017-10-17	Life Sciences Research Partners Vzw	Inmunoterapia dirigida a patógenos intracelulares
EP2245059B1 (en)	2008-02-14	2017-09-20	Life Sciences Research Partners VZW	Cd4+ t-cells with cytolytic properties
EP2331124A1 (en)	2008-08-15	2011-06-15	Circassia Limited	T-cell antigen peptide from allergen for stimulation of il-10 production
GB0821806D0 (en)	2008-11-28	2009-01-07	Circassia Ltd	Compositions with reduced dimer formation
DE11787873T1 (de)	2010-11-25	2013-12-12	Imnate Sarl	Immugene Peptide zur Verwendung bei der Vorbeugung und/oder Behandlung von Infektionskrankheiten, Autoimmunerkrankungen, Immunreaktionen auf Allofaktoren, allergischen Erkrankungen, Tumoren, Transplantatabstossungen und Immunreaktionen auf virale Vektoren
GB201201511D0 (en)	2012-01-30	2012-03-14	Univ Leuven Kath	Modified epitopes for boosting CD4+ T-cell responses
GB201309469D0 (en)	2013-05-28	2013-07-10	Imcyse Sa	Detection of CD4+ T lymphocytes
CA2914037A1 (en) *	2013-06-06	2014-12-11	Anergis S.A.	Contiguous overlapping peptides for treatment of house dust mites allergy
US10729791B2 (en)	2015-05-18	2020-08-04	Imcyse Sa	Animal models for evaluating pharmaceutical compounds
CA2995771A1 (en)	2015-09-25	2017-03-30	Imcyse Sa	Improved methods and compounds for eliminating immune responses to therapeutic agents
BR112018071466A2 (pt)	2016-04-19	2019-03-19	Imcyse Sa	novos peptídeos de ligação a cd1d imunogênicos
US11826423B2 (en) *	2016-11-16	2023-11-28	Immunomic Therapeutics, Inc.	Nucleic acids for treatment of allergies
KR102010436B1 (ko) *	2018-02-28	2019-08-13	을지대학교 산학협력단	신규 알러지 반응 검사용 조성물
GB202409214D0 (en) *	2024-06-26	2024-08-07	Univ Birmingham	tolerogenic peptides

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4234569A (en) *	1978-10-04	1980-11-18	The Johns Hopkins University	Production of aldehyde-treated allergen-containing substances
JP2993967B2 (ja) *	1987-06-17	1999-12-27	インスティテュート・フォー・チャイルド・ヘルス・リサーチ	ダニアレルゲンのクローニング
FR2650181B1 (fr) *	1989-07-27	1993-12-03	Laboratoire Stallergenes	Procede pour combiner un melange de substances heterogenes a des liposomes
ES2174822T3 (es) *	1989-11-03	2002-11-16	Immulogic Pharma Corp	Una proteina felina reactiva con celulas t humanas (trfp) aislada de polvo domestico y usos para la misma.
JP2596466B2 (ja) *	1990-03-03	1997-04-02	アサヒビール株式会社	ダニの主要アレルゲンの還伝情報を有するｄｎａおよび該アレルゲンの製造方法
DE69131131T2 (de) *	1990-09-11	1999-10-14	Institute For Child Health Research	Klonierung und sequenzierung von dermatophagoiden-antigenen (hausstaubmilben)

1992
- 1992-10-15 DE DE69233772T patent/DE69233772D1/de not_active Expired - Lifetime
- 1992-10-15 KR KR1019940701293A patent/KR100260342B1/ko not_active Expired - Lifetime
- 1992-10-15 JP JP5507733A patent/JPH07502890A/ja active Pending
- 1992-10-15 AT AT92922076T patent/ATE444360T1/de active
- 1992-10-15 WO PCT/US1992/008637 patent/WO1993008279A1/en not_active Ceased
- 1992-10-15 EP EP92922076A patent/EP0623168B1/en not_active Expired - Lifetime
- 1992-10-15 HU HU9401108A patent/HU220462B1/hu unknown
- 1992-10-15 ES ES92922076T patent/ES2334179T3/es not_active Expired - Lifetime
- 1992-10-15 AU AU28654/92A patent/AU676668B2/en not_active Expired
- 1992-10-16 IL IL10345292A patent/IL103452A/en not_active IP Right Cessation
- 1992-10-16 MX MX9205985A patent/MX9205985A/es active IP Right Grant
- 1992-10-16 PT PT100979A patent/PT100979B/pt not_active IP Right Cessation
- 1992-10-16 NZ NZ244772A patent/NZ244772A/en not_active IP Right Cessation
1994
- 1994-04-15 FI FI941757A patent/FI110385B/fi not_active IP Right Cessation
- 1994-04-15 NO NO19941371A patent/NO314586B1/no not_active IP Right Cessation
2008
- 2008-08-05 JP JP2008202456A patent/JP2009005709A/ja active Pending

Also Published As

Publication number	Publication date
NZ244772A (en)	1995-09-26
JPH07502890A (ja)	1995-03-30
DE69233772D1 (de)	2009-11-12
AU676668B2 (en)	1997-03-20
JP2009005709A (ja)	2009-01-15
EP0623168B1 (en)	2009-09-30
NO941371L (no)	1994-06-15
IL103452A (en)	2004-07-25
MX9205985A (es)	1993-08-01
AU2865492A (en)	1993-05-21
IL103452A0 (en)	1993-03-15
HU220462B1 (hu)	2002-02-28
EP0623168A1 (en)	1994-11-09
FI941757L (fi)	1994-06-16
KR100260342B1 (ko)	2000-07-01
KR940702936A (ko)	1994-09-17
ES2334179T3 (es)	2010-03-05
HU9401108D0 (en)	1994-08-29
FI110385B (fi)	2003-01-15
PT100979B (pt)	1999-08-31
NO941371D0 (no)	1994-04-15
WO1993008279A1 (en)	1993-04-29
NO314586B1 (no)	2003-04-14
ATE444360T1 (de)	2009-10-15
FI941757A0 (fi)	1994-04-15
HUT71211A (en)	1995-11-28

Legal Events

Date	Code	Title	Description
1994-01-31	BB1A	Laying open of patent application	Effective date: 19930701
1999-08-31	FG3A	Patent granted, date of granting	Effective date: 19990506
2007-01-31	PC4A	Transfer of assignment	Owner name: HESKA CORPORATION, US Effective date: 20061205
2007-01-31	TE4A	Change of address (patent)	Owner name: HESKA CORPORATION, US Effective date: 20061207
2007-07-13	PC4A	Transfer of assignment	Owner name: MERCK PATENT GMBH, DE Effective date: 20070703
2014-05-14	MM4A	Annulment/lapse due to non-payment of fees, searched and examined patent	Free format text: MAXIMUM VALIDITY LIMIT REACHED Effective date: 20140506

Publication	Publication Date	Title
PT100979A (pt)	1994-01-31	Epitopos de celula t dos alergenos principais de dermatophagoides (acaro do po domestico), peptidos modificados, sequencias de acidos nucleicos que os codificam, composicoes farmaceuticas que os contem e seu uso
ATE178940T1 (de)	1999-04-15	Klonierung und sequenzierung von dermatophagoiden-antigenen (hausstaubmilben)
ATE352559T1 (de)	2007-02-15	Verfahren zur verminderung der immunogenität von proteinen
ES2163444T3 (es)	2002-02-01	Composiciones y metodos para la administracion oral de farmacos.
PT100978A (pt)	1994-01-31	Peptidos recombitopos, sequencias de acidos nucleicos que os codificam, composicoes terapeuticas que os contem e seu uso
ATE54826T1 (de)	1990-08-15	Thymusextraktfraktionen enthaltende pharmazeutische zusammensetzung.
AR013528A1 (es)	2000-12-27	PROTEíNA-2 QUIMIOTÁCTICA MONOCíTICA (MCP-2) HUMANA AMINO TERMINALMENTE TRUNCADA, MOLÉCULA DE ADN QUE LA CODIFICA, VECTOR DE EXPRESIoN Y CÉLULA HUÉSPED CORRESPONDIENTES, PROCESO RECOMBINANTE PARA PREPARAR DICHAS PROTEíNAS, USO DE DICHAS PROTEíNAS PARA LA FABRICACIoN DE UN MEDICAMENTO uTIL PARA LA TER
DE3877547D1 (de)	1993-02-25	Basisches protein phospholipase a2 aus dem gift der schlangen aus der familie der elapiden, deren aminosaeuresequenz, derivate und fragmente dieses proteins, verfahren um es zu erhalten, therapeutische kompositionen und diagnosemittel, alle dieses protein enthaltend und/oder dessen derivate und/oder dessen fragmente.
NO953571L (no)	1995-11-10	T-celle-epitoper av vanlig raigress-pollen allergen
ES549115A0 (es)	1986-12-01	Procedimiento de producir preparaciones para tratar pacien- tes de hemofilia a inhibidores
NO960553L (no)	1996-04-12	T-celle-epitoper av raigresspollen-allergen
NO943811L (no)	1994-12-06	T-celle-epitoper av hovedallergenene fra Ambriosa artemisiifolia
FI950602A0 (fi)	1995-02-10	Raiheinän siitepolyallergeenin T-soluepitoopit
Romagnani et al.	1976	Studies on allergens of Dermatophagoides pteronyssinus by direct and indirect RAST
ATE359296T1 (de)	2007-05-15	Pharmazeutische peptide formulierungen zur behandlung von staubmilben allergie
Bengis-Garber et al.	1993	Calcium-binding myeloid protein (P8, 14) is phosphorylated in fMet-Leu-Phe-stimulated neutrophils
NO892266D0 (no)	1989-06-02	Amblyommin, et nytt virkemiddel for antikoagulasjonsterapien.
ES2083636T3 (es)	1996-04-16	Componente adhesivo para la restauracion de la sustancia dental dura.
ES2057008T3 (es)	1994-10-16	Medicamento.
NO881661D0 (no)	1988-04-15	Humane rhinoviruspeptider.