IL131250A - Bite Compounds - (2 - Acylaminophenyl) Disulfide and Compounds 2 - Acylamino - Phenylthio and Pharmaceutical Preparations Containing Them - Google Patents
Bite Compounds - (2 - Acylaminophenyl) Disulfide and Compounds 2 - Acylamino - Phenylthio and Pharmaceutical Preparations Containing ThemInfo
- Publication number
- IL131250A IL131250A IL13125098A IL13125098A IL131250A IL 131250 A IL131250 A IL 131250A IL 13125098 A IL13125098 A IL 13125098A IL 13125098 A IL13125098 A IL 13125098A IL 131250 A IL131250 A IL 131250A
- Authority
- IL
- Israel
- Prior art keywords
- group
- phenyl
- substituted
- isopentylcyclohexanecarbonylamino
- unsubstituted
- Prior art date
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- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
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- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
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- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
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- C07C333/10—Monothiocarbamic acids; Derivatives thereof having nitrogen atoms of thiocarbamic groups being part of any of the groups, X being a hetero atom, Y being any atom, e.g., N-acyl-thiocarbamates
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- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Pyrrole Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Cosmetics (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4483697 | 1997-02-12 | ||
| JP16508597 | 1997-06-05 | ||
| JP10026688A JP2894445B2 (ja) | 1997-02-12 | 1998-01-23 | Cetp活性阻害剤として有効な化合物 |
| PCT/JP1998/000542 WO1998035937A1 (fr) | 1997-02-12 | 1998-02-10 | Inhibiteurs de l'activite du cetp |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL131250A0 IL131250A0 (en) | 2001-01-28 |
| IL131250A true IL131250A (en) | 2004-12-15 |
Family
ID=27285497
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13125098A IL131250A (en) | 1997-02-12 | 1998-02-10 | Bite Compounds - (2 - Acylaminophenyl) Disulfide and Compounds 2 - Acylamino - Phenylthio and Pharmaceutical Preparations Containing Them |
| IL164569A IL164569A (en) | 1997-02-12 | 2004-10-14 | Use of compounds that selectively inhibit cetp activity for preparing compositions for treating hyperlipidemia or atherosclerosis |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL164569A IL164569A (en) | 1997-02-12 | 2004-10-14 | Use of compounds that selectively inhibit cetp activity for preparing compositions for treating hyperlipidemia or atherosclerosis |
Country Status (24)
| Country | Link |
|---|---|
| US (6) | US6426365B1 (fr) |
| EP (3) | EP2292596A3 (fr) |
| JP (1) | JP2894445B2 (fr) |
| KR (1) | KR100324183B1 (fr) |
| CN (1) | CN100384821C (fr) |
| AT (1) | ATE338029T1 (fr) |
| AU (1) | AU728979B2 (fr) |
| BR (1) | BRPI9807222B8 (fr) |
| CA (1) | CA2280708C (fr) |
| CY (1) | CY2587B2 (fr) |
| CZ (1) | CZ302069B6 (fr) |
| DE (1) | DE69835760T2 (fr) |
| DK (1) | DK1020439T3 (fr) |
| ES (1) | ES2270504T3 (fr) |
| HU (1) | HU227763B1 (fr) |
| ID (1) | ID22667A (fr) |
| IL (2) | IL131250A (fr) |
| NO (1) | NO314228B1 (fr) |
| NZ (1) | NZ337122A (fr) |
| PT (1) | PT1020439E (fr) |
| RU (1) | RU2188631C2 (fr) |
| SK (1) | SK282973B6 (fr) |
| TW (1) | TW577865B (fr) |
| WO (1) | WO1998035937A1 (fr) |
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1998
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- 1998-02-10 NZ NZ337122A patent/NZ337122A/en not_active IP Right Cessation
- 1998-02-10 EP EP10012389A patent/EP2292596A3/fr not_active Withdrawn
- 1998-02-10 AT AT98901574T patent/ATE338029T1/de active
- 1998-02-10 CZ CZ0278899A patent/CZ302069B6/cs not_active IP Right Cessation
- 1998-02-10 DK DK98901574T patent/DK1020439T3/da active
- 1998-02-10 IL IL13125098A patent/IL131250A/en not_active IP Right Cessation
- 1998-02-10 HU HU0002483A patent/HU227763B1/hu unknown
- 1998-02-10 PT PT98901574T patent/PT1020439E/pt unknown
- 1998-02-10 EP EP98901574A patent/EP1020439B1/fr not_active Expired - Lifetime
- 1998-02-10 DE DE69835760T patent/DE69835760T2/de not_active Expired - Lifetime
- 1998-02-10 WO PCT/JP1998/000542 patent/WO1998035937A1/fr not_active Ceased
- 1998-02-10 AU AU57818/98A patent/AU728979B2/en not_active Expired
- 1998-02-10 CA CA002280708A patent/CA2280708C/fr not_active Expired - Lifetime
- 1998-02-10 KR KR1019997007248A patent/KR100324183B1/ko not_active Expired - Lifetime
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- 1998-02-10 CN CNB988040425A patent/CN100384821C/zh not_active Expired - Lifetime
- 1998-02-10 BR BRPI9807222A patent/BRPI9807222B8/pt not_active IP Right Cessation
- 1998-02-10 RU RU99119494/04A patent/RU2188631C2/ru active
- 1998-02-10 ID IDW991011A patent/ID22667A/id unknown
- 1998-02-10 ES ES98901574T patent/ES2270504T3/es not_active Expired - Lifetime
- 1998-02-10 EP EP06013250A patent/EP1710231A1/fr not_active Withdrawn
- 1998-02-10 SK SK1095-99A patent/SK282973B6/sk not_active IP Right Cessation
- 1998-02-11 TW TW087101827A patent/TW577865B/zh not_active IP Right Cessation
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1999
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2002
- 2002-05-22 US US10/151,813 patent/US6753346B2/en not_active Expired - Lifetime
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2004
- 2004-04-15 US US10/825,531 patent/US7271196B2/en not_active Expired - Fee Related
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2007
- 2007-08-03 US US11/833,859 patent/US7579379B2/en not_active Expired - Fee Related
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2009
- 2009-07-13 US US12/502,012 patent/US20100197736A1/en not_active Abandoned
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2012
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