IL134185A - Preparation of nevirapine hemihydrate and pharmaceutical suspensions containing it - Google Patents

Preparation of nevirapine hemihydrate and pharmaceutical suspensions containing it

Info

Publication number
IL134185A
IL134185A IL13418598A IL13418598A IL134185A IL 134185 A IL134185 A IL 134185A IL 13418598 A IL13418598 A IL 13418598A IL 13418598 A IL13418598 A IL 13418598A IL 134185 A IL134185 A IL 134185A
Authority
IL
Israel
Prior art keywords
preparation
suspensions containing
pharmaceutical suspensions
nevirapine hemihydrate
nevirapine
Prior art date
Application number
IL13418598A
Other languages
English (en)
Other versions
IL134185A0 (en
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22006658&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL134185(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of IL134185A0 publication Critical patent/IL134185A0/xx
Publication of IL134185A publication Critical patent/IL134185A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL13418598A 1997-08-25 1998-08-11 Preparation of nevirapine hemihydrate and pharmaceutical suspensions containing it IL134185A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5680397P 1997-08-25 1997-08-25
PCT/US1998/016581 WO1999009990A1 (en) 1997-08-25 1998-08-11 Pharmaceutical suspension comprising nevirapine hemihydrate

Publications (2)

Publication Number Publication Date
IL134185A0 IL134185A0 (en) 2001-04-30
IL134185A true IL134185A (en) 2005-11-20

Family

ID=22006658

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13418598A IL134185A (en) 1997-08-25 1998-08-11 Preparation of nevirapine hemihydrate and pharmaceutical suspensions containing it

Country Status (37)

Country Link
US (2) US6172059B1 (cs)
EP (1) EP1019058B1 (cs)
JP (1) JP3472261B2 (cs)
KR (1) KR100426516B1 (cs)
CN (1) CN1197578C (cs)
AR (2) AR016869A1 (cs)
AT (1) ATE326971T1 (cs)
AU (1) AU742761B2 (cs)
BG (1) BG64337B1 (cs)
BR (1) BR9811994B1 (cs)
CA (1) CA2301646C (cs)
CL (1) CL2008003111A1 (cs)
CO (1) CO4970742A1 (cs)
CY (1) CY1105228T1 (cs)
CZ (1) CZ290667B6 (cs)
DE (1) DE69834655T2 (cs)
DK (1) DK1019058T3 (cs)
EG (1) EG24075A (cs)
ES (1) ES2265666T3 (cs)
HR (1) HRP980461B1 (cs)
HU (1) HU226063B1 (cs)
ID (1) ID21650A (cs)
IL (1) IL134185A (cs)
MY (1) MY122272A (cs)
NO (1) NO326226B1 (cs)
NZ (1) NZ503414A (cs)
PE (1) PE105799A1 (cs)
PL (1) PL192361B1 (cs)
PT (1) PT1019058E (cs)
RS (1) RS49808B (cs)
RU (1) RU2196584C2 (cs)
SA (1) SA98190680B1 (cs)
TR (1) TR200000490T2 (cs)
TW (1) TW450812B (cs)
UA (1) UA44370C2 (cs)
WO (1) WO1999009990A1 (cs)
ZA (1) ZA987623B (cs)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002092095A1 (en) * 2001-05-11 2002-11-21 Boehringer Ingelheim International Gmbh Use of nevirapine to treat or prevent lipid pathology in patients with hiv that is resistant to nevirapine
CA2479943A1 (en) * 2002-04-23 2003-11-06 Boehringer Ingelheim Pharmaceuticals, Inc. Method for reduction of residual organic solvent in carbomer
KR20080053317A (ko) * 2005-08-31 2008-06-12 씨아이피엘에이 엘티디. 라미부딘, 스타부딘 및 네비라핀을 포함하는 약학적 조합물
EP2306980A2 (en) * 2008-06-30 2011-04-13 Tibotec Pharmaceuticals Powders for reconstitution
US9273049B2 (en) * 2009-11-10 2016-03-01 North-West University Method for increasing the solubility of nevirapine
CN102725293A (zh) * 2009-12-17 2012-10-10 西北大学 奈韦拉平的多晶型形式及其制备

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5366972A (en) 1989-04-20 1994-11-22 Boehringer Ingelheim Pharmaceuticals, Inc. 5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection
ES2063202T3 (es) * 1989-06-28 1995-01-01 Boehringer Ingelheim Pharma Nuevas 5,11-dihidro-6h-dipirido(3,2-b:2',3'-e)(1,4)diazepin-6-onas y -tionas y su uso en la prevencion o tratamiento del sida.
CA2030056C (en) * 1989-11-17 1995-10-17 Karl D. Hargrave 5,11-dihydro-6h-dipyrido[3,2-b:2',3'-e][1,4]diazepines and their use in the prevention or treatment of hiv infection
US5571912A (en) * 1990-10-19 1996-11-05 Boehringer Ingelheim Pharmaceuticals, Inc. Method for the preparation of 5,11-dihydro-6h-dipyrido [3,2-b:2',3'-e][1,4]diazepines
GB9215178D0 (en) * 1992-07-16 1992-08-26 Glaxo Group Ltd Antiviral combinations
HUT74681A (en) * 1993-12-15 1997-01-28 Merck & Co Inc N-(2-hydroxy-1-indenyl)-2-phenylmethyl-4-hydroxy-5-(2-carboxamido-piperazinyl)-pentaneamide derivatives of hiv protease inhibitor activity and phrmaceutical compositions contining them
DE4403311C1 (de) * 1994-02-03 1995-04-20 Boehringer Ingelheim Kg Verfahren zur Herstellung von Nevirapine (11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4-diazepin]-6-on)

Also Published As

Publication number Publication date
AU742761B2 (en) 2002-01-10
KR20010023257A (ko) 2001-03-26
NZ503414A (en) 2002-11-26
US6172059B1 (en) 2001-01-09
NO20000906D0 (no) 2000-02-24
RS49808B (sr) 2008-08-07
MY122272A (en) 2006-04-29
CN1197578C (zh) 2005-04-20
AU8777198A (en) 1999-03-16
HK1027975A1 (en) 2001-02-02
JP2001513564A (ja) 2001-09-04
TW450812B (en) 2001-08-21
PT1019058E (pt) 2006-08-31
EP1019058B1 (en) 2006-05-24
PL338828A1 (en) 2000-11-20
HU226063B1 (hu) 2008-04-28
ES2265666T3 (es) 2007-02-16
CZ2000694A3 (cs) 2000-09-13
JP3472261B2 (ja) 2003-12-02
YU9800A (sh) 2001-12-26
ZA987623B (en) 2000-03-22
SA98190680B1 (ar) 2006-04-04
DE69834655D1 (de) 2006-06-29
KR100426516B1 (ko) 2004-04-13
NO326226B1 (no) 2008-10-20
HUP0003093A2 (hu) 2001-08-28
EP1019058A1 (en) 2000-07-19
ID21650A (id) 1999-07-08
HRP980461A2 (en) 1999-06-30
DK1019058T3 (da) 2006-06-12
CA2301646C (en) 2008-11-18
US6255481B1 (en) 2001-07-03
PE105799A1 (es) 1999-11-16
DE69834655T2 (de) 2006-12-14
CL2008003111A1 (es) 2009-09-11
BR9811994B1 (pt) 2013-11-19
NO20000906L (no) 2000-02-24
BR9811994A (pt) 2000-09-05
AR016869A1 (es) 2001-08-01
CY1105228T1 (el) 2010-03-03
AR083451A2 (es) 2013-02-27
UA44370C2 (uk) 2002-02-15
ATE326971T1 (de) 2006-06-15
CZ290667B6 (cs) 2002-09-11
BG104133A (bg) 2000-08-31
BG64337B1 (bg) 2004-10-29
EG24075A (en) 2008-05-11
RU2196584C2 (ru) 2003-01-20
TR200000490T2 (tr) 2000-08-21
CA2301646A1 (en) 1999-03-04
PL192361B1 (pl) 2006-10-31
WO1999009990A1 (en) 1999-03-04
HRP980461B1 (en) 2002-08-31
IL134185A0 (en) 2001-04-30
EP1019058A4 (en) 2004-11-10
CO4970742A1 (es) 2000-11-07
CN1268055A (zh) 2000-09-27

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Legal Events

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KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees