IL141133A - Process for preparing N,N,6-trimethyl-2-(4-methylphenyl)-imidazo-Ä1,2-AÜ- pyridine-3-acetamide and salts thereof - Google Patents

Process for preparing N,N,6-trimethyl-2-(4-methylphenyl)-imidazo-Ä1,2-AÜ- pyridine-3-acetamide and salts thereof

Info

Publication number: IL141133A
Authority: IL; Israel
Prior art keywords: imidazo; acetamide; methylphenyl; trimethyl; pyridine
Prior art date: 1998-08-06

Application number

IL14113399A

Other languages

English (en)

Other versions

IL141133A0 (en

Original Assignee

Sint Quimica Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-08-06

Filing date

1999-08-04

Publication date

2005-11-20

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8304817&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL141133(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-08-04 Application filed by Sint Quimica Sa filed Critical Sint Quimica Sa

2002-02-10 Publication of IL141133A0 publication Critical patent/IL141133A0/xx

2005-11-20 Publication of IL141133A publication Critical patent/IL141133A/xx

Links

238000004519 manufacturing process Methods 0.000 title 1
150000003839 salts Chemical class 0.000 title 1
ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 4
ROSDSFDQCJNGOL-UHFFFAOYSA-N Dimethylamine Chemical compound CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 abstract 2
FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
239000003638 chemical reducing agent Substances 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
-1 hydroxy ester Chemical class 0.000 abstract 1
150000007975 iminium salts Chemical class 0.000 abstract 1
238000011065 in-situ storage Methods 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IL14113399A 1998-08-06 1999-08-04 Process for preparing N,N,6-trimethyl-2-(4-methylphenyl)-imidazo-Ä1,2-AÜ- pyridine-3-acetamide and salts thereof IL141133A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
ES009801694A ES2151834B1 (es)	1998-08-06	1998-08-06	Procedimiento para preparar n,n,6-trimetil-2-(4-metilfenil)-imidazo-(1,2-a)-piridina-3-acetamida y sus sales.
PCT/ES1999/000250 WO2000008021A2 (es)	1998-08-06	1999-08-04	Procedimiento para preparar n,n,6- trimetil-2- (4-metilfenil)- imidazo-[1,2-a] -piridina-3- acetamida y sus sales

Publications (2)

Publication Number	Publication Date
IL141133A0 IL141133A0 (en)	2002-02-10
IL141133A true IL141133A (en)	2005-11-20

Family

ID=8304817

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL14113399A IL141133A (en)	1998-08-06	1999-08-04	Process for preparing N,N,6-trimethyl-2-(4-methylphenyl)-imidazo-Ä1,2-AÜ- pyridine-3-acetamide and salts thereof

Country Status (25)

Country	Link
US (1)	US6407240B1 (de)
EP (1)	EP1104765B2 (de)
JP (1)	JP3544944B2 (de)
KR (1)	KR100492054B1 (de)
AT (1)	ATE234836T1 (de)
AU (1)	AU750302B2 (de)
CA (1)	CA2339594C (de)
CZ (1)	CZ292446B6 (de)
DE (1)	DE69906088T3 (de)
DK (1)	DK1104765T4 (de)
ES (2)	ES2151834B1 (de)
HR (1)	HRP20010158B1 (de)
HU (1)	HUP0102936A3 (de)
IL (1)	IL141133A (de)
IS (1)	IS5839A (de)
NO (1)	NO319780B1 (de)
NZ (1)	NZ510310A (de)
PL (1)	PL195888B1 (de)
PT (1)	PT1104765E (de)
RS (1)	RS50103B (de)
RU (1)	RU2221797C2 (de)
SI (1)	SI1104765T2 (de)
SK (1)	SK283652B6 (de)
WO (1)	WO2000008021A2 (de)
ZA (1)	ZA200101294B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2151834B1 (es) †	1998-08-06	2001-08-16	Sint Quimica Sa	Procedimiento para preparar n,n,6-trimetil-2-(4-metilfenil)-imidazo-(1,2-a)-piridina-3-acetamida y sus sales.
HRP20020471B1 (en) *	1999-11-22	2007-12-31	Egis Gy�gyszergy�r RT	Process for the preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyrimidine-3-(n,n-dimethyl-acetamide) and intermediates
IT1318624B1 (it)	2000-07-14	2003-08-27	Dinamite Dipharma S P A In For	Processo per la preparazione di 2-fenil-imidazo (1,2-a)piridin-3-acetammidi.
US6596731B2 (en)	2001-03-27	2003-07-22	Hoffmann-La Roche Inc.	Substituted imidazo[1,2-A] pyridine derivatives
WO2004007496A1 (en) *	2002-07-15	2004-01-22	Scinopharm Taiwan, Ltd.	Process for the preparation of imidazo(1,2-a)pyridine-3-acetamides
ES2320758T3 (es)	2002-12-18	2009-05-28	Mallinckrodt Inc.	Sintesis de heteroaril acetamidas.
ATE451371T1 (de) *	2004-06-22	2009-12-15	Mallinckrodt Inc	Synthese von heteroarylacetamiden aus reaktionsmischungen mit reduziertem wassergehalt
WO2007040995A1 (en) *	2005-10-03	2007-04-12	Mallinckrodt Inc.	Process for preparing zolpidem hemitartrate and tartrate polymorphs
EP1803722A1 (de) *	2006-01-03	2007-07-04	Ferrer Internacional, S.A.	Imidazo[1,2-a]pyridin-3-yl-Essigsäure-Hydrazide, Verfahren zur ihrer Herstellung und ihre Verwendung als Arzneimittel
US20080145425A1 (en) *	2006-12-15	2008-06-19	Pliva Research & Development Limited	Pharmaceutical composition of zolpidem
CN103360387B (zh) *	2012-03-28	2016-12-14	江苏豪森药业集团有限公司	一种制备化合物唑吡坦的方法
CN104610253B (zh) *	2015-01-26	2016-11-16	郑州大学	2‑三氟甲基‑2‑羟基‑2‑(2‑芳基吡啶并[1,2‑α]咪唑)乙酸酯类化合物
CN114105974A (zh) *	2020-08-27	2022-03-01	鲁南制药集团股份有限公司	一种唑吡坦的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2600650B1 (fr) *	1986-06-27	1988-09-09	Synthelabo	Procede de preparation d'imidazopyridines et composes intermediaires
ES2151834B1 (es) †	1998-08-06	2001-08-16	Sint Quimica Sa	Procedimiento para preparar n,n,6-trimetil-2-(4-metilfenil)-imidazo-(1,2-a)-piridina-3-acetamida y sus sales.

1998
- 1998-08-06 ES ES009801694A patent/ES2151834B1/es not_active Expired - Fee Related
1999
- 1999-08-04 US US09/762,205 patent/US6407240B1/en not_active Expired - Fee Related
- 1999-08-04 NZ NZ510310A patent/NZ510310A/xx unknown
- 1999-08-04 KR KR10-2001-7001385A patent/KR100492054B1/ko not_active Expired - Fee Related
- 1999-08-04 PL PL99346158A patent/PL195888B1/pl not_active IP Right Cessation
- 1999-08-04 AT AT99938403T patent/ATE234836T1/de not_active IP Right Cessation
- 1999-08-04 PT PT99938403T patent/PT1104765E/pt unknown
- 1999-08-04 AU AU52912/99A patent/AU750302B2/en not_active Ceased
- 1999-08-04 DE DE69906088T patent/DE69906088T3/de not_active Expired - Lifetime
- 1999-08-04 EP EP99938403A patent/EP1104765B2/de not_active Expired - Lifetime
- 1999-08-04 SK SK159-2001A patent/SK283652B6/sk not_active IP Right Cessation
- 1999-08-04 WO PCT/ES1999/000250 patent/WO2000008021A2/es not_active Ceased
- 1999-08-04 CZ CZ2001360A patent/CZ292446B6/cs not_active IP Right Cessation
- 1999-08-04 DK DK99938403T patent/DK1104765T4/da active
- 1999-08-04 SI SI9930286T patent/SI1104765T2/sl unknown
- 1999-08-04 RS YUP-83/01A patent/RS50103B/sr unknown
- 1999-08-04 ES ES99938403T patent/ES2195598T5/es not_active Expired - Lifetime
- 1999-08-04 JP JP2000563654A patent/JP3544944B2/ja not_active Expired - Fee Related
- 1999-08-04 HR HR20010158A patent/HRP20010158B1/xx not_active IP Right Cessation
- 1999-08-04 HU HU0102936A patent/HUP0102936A3/hu unknown
- 1999-08-04 IL IL14113399A patent/IL141133A/xx not_active IP Right Cessation
- 1999-08-04 RU RU2001106627/04A patent/RU2221797C2/ru not_active IP Right Cessation
- 1999-08-04 CA CA002339594A patent/CA2339594C/en not_active Expired - Fee Related
2001
- 2001-02-05 NO NO20010613A patent/NO319780B1/no not_active IP Right Cessation
- 2001-02-05 IS IS5839A patent/IS5839A/is unknown
- 2001-02-15 ZA ZA200101294A patent/ZA200101294B/en unknown

Also Published As

Publication number	Publication date
KR20010072173A (ko)	2001-07-31
NZ510310A (en)	2002-11-26
CZ292446B6 (cs)	2003-09-17
CA2339594C (en)	2005-05-03
IS5839A (is)	2001-02-05
JP2002522437A (ja)	2002-07-23
JP3544944B2 (ja)	2004-07-21
RU2221797C2 (ru)	2004-01-20
NO20010613D0 (no)	2001-02-05
AU750302B2 (en)	2002-07-18
ES2195598T5 (es)	2008-05-01
ES2151834B1 (es)	2001-08-16
ES2151834A1 (es)	2001-01-01
SI1104765T2 (sl)	2008-04-30
SK1592001A3 (en)	2001-12-03
HRP20010158B1 (en)	2003-12-31
ZA200101294B (en)	2002-02-15
PL346158A1 (en)	2002-01-28
KR100492054B1 (ko)	2005-05-31
WO2000008021A2 (es)	2000-02-17
CA2339594A1 (en)	2000-02-17
DK1104765T4 (da)	2008-03-03
DE69906088D1 (de)	2003-04-24
US6407240B1 (en)	2002-06-18
PT1104765E (pt)	2003-08-29
NO20010613L (no)	2001-02-05
ATE234836T1 (de)	2003-04-15
RS50103B (sr)	2009-01-22
YU8301A (sh)	2003-10-31
NO319780B1 (no)	2005-09-12
WO2000008021A3 (es)	2000-07-06
DE69906088T3 (de)	2008-04-30
SI1104765T1 (en)	2003-08-31
HRP20010158A2 (en)	2002-02-28
HK1037624A1 (en)	2002-02-15
DK1104765T3 (da)	2003-06-30
EP1104765B2 (de)	2007-11-14
HUP0102936A2 (hu)	2002-01-28
PL195888B1 (pl)	2007-11-30
IL141133A0 (en)	2002-02-10
AU5291299A (en)	2000-02-28
SK283652B6 (sk)	2003-11-04
EP1104765B1 (de)	2003-03-19
ES2195598T3 (es)	2003-12-01
EP1104765A2 (de)	2001-06-06
HUP0102936A3 (en)	2002-09-30
DE69906088T2 (de)	2003-12-24
CZ2001360A3 (cs)	2001-12-12

Legal Events

Date	Code	Title	Description
2006-02-21	FF	Patent granted
2010-10-31	MM9K	Patent not in force due to non-payment of renewal fees

Publication	Publication Date	Title
SI1104765T2 (sl)	2008-04-30	Postopek za pripravo n,n,6-trimetil-2-(4-metilfenil)-imidazo-(1,2-a)-piridin-3-acetamida in njegovih soli
DK1029861T3 (da)	2004-11-15	Benzisothiazol-piperazinylderivat og dets anvendelse som neuroleptikum
NO2001022I2 (no)	2005-10-10	Analogifremgangsmate for fremstilling av terapeutisk virksomme 2-(4-(difenylmethyl)-1-piperazinyl)-eddiksyrer og deres amider og ikke-toksiske salter
PL291472A1 (en)	1992-07-13	Method of obtaining novel derivatives of n-aryl and n-heteroaryl amide
SE9003476L (sv)	1992-05-01	Novel isoindole derivatives and salts thereof, process for producing the same and antitumor agent comprising the same
EP1247792A3 (de)	2003-10-29	Verfahren zur Herstellung von halogensubstituierten Dibenzylalkoholen, diese halogensubstituierten Dibenzylalkohole sowie deren Verwendung
DK119684A (da)	1984-09-13	Quinoloncarboxylsyrer og disses anvendelse som baktericider
ZA925080B (en)	1993-04-28	Naphthylamine polycarboxylic acids.
ES2089097T3 (es)	1996-10-01	Procedimiento para la fabricacion de derivados de bencilftalacinona y sales de la misma.
DE3460467D1 (en)	1986-09-18	Hydroquinone derivatives and production thereof
PH21982A (en)	1988-05-02	N-(3-triflouromethyl-phenyl)-n'-propargylpiperazine and method of use thereof
DE50100015D1 (de)	2002-09-12	Ester aromatischer Hydroxycarbonsäuren
ATE159519T1 (de)	1997-11-15	Verfahren zur herstellung von n-phenyl-n-(4- piperidinyl)amid-derivaten
JPS5350182A (en)	1978-05-08	Carbostyril derivatives
ATE251616T1 (de)	2003-10-15	Verfahren zur herstellung von 5- hydroxymethylthiazole
JPS5751000A (en)	1982-03-25	Ester derivative of alkoxybenzoyldeoxyfluorouridine
ATE116286T1 (de)	1995-01-15	Verfahren zur herstellung eines aliphatischen amides und salzen davon.
ATE248149T1 (de)	2003-09-15	Verfahren zur herstellung von 3-(3-pyridyl)-1- propanol derivaten
ES389687A1 (es)	1974-03-01	Un procedimiento de preparacion de derivados de carbonil- dioximorfinano.
ES451953A1 (es)	1977-10-16	Un procedimiento para la produccion de un derivado de benza-mida.
RU99110038A (ru)	2001-06-10	Способ подготовки плодов или овощей к хранению
JPS5677273A (en)	1981-06-25	Flavan derivative and its acid addition salt