|
US7048906B2
(en)
|
1995-05-17 |
2006-05-23 |
Cedars-Sinai Medical Center |
Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
|
|
AU757658B2
(en)
|
1998-03-09 |
2003-02-27 |
Zealand Pharma A/S |
Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
|
|
SE9801571D0
(sv)
|
1998-05-05 |
1998-05-05 |
Wapharm Ab |
Melanokortin-1-receptorselektiva föreningar
|
|
US6444788B1
(en)
|
1999-03-15 |
2002-09-03 |
Novo Nordisk A/S |
Ion exchange chromatography of GLP-1, analogs and derivatives thereof
|
|
US6528486B1
(en)
|
1999-07-12 |
2003-03-04 |
Zealand Pharma A/S |
Peptide agonists of GLP-1 activity
|
|
US7371721B2
(en)
|
2000-09-18 |
2008-05-13 |
Sanos Bioscience A/S |
Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes
|
|
WO2002022151A2
(en)
|
2000-09-18 |
2002-03-21 |
Osteometer Bio Tech A/S |
Use of glp-1 and flp-2 peptides for treatment of bone disorders
|
|
EP2186824A3
(en)
|
2000-12-13 |
2010-09-22 |
Eli Lilly & Company |
Chronic treatment regimen using glucagon-like insulinotropic peptides
|
|
CN1162446C
(zh)
|
2001-05-10 |
2004-08-18 |
上海华谊生物技术有限公司 |
促胰岛素分泌肽衍生物
|
|
CN1158304C
(zh)
*
|
2001-05-10 |
2004-07-21 |
上海华谊生物技术有限公司 |
蛙皮抗菌肽衍生物
|
|
US20030119734A1
(en)
|
2001-06-28 |
2003-06-26 |
Flink James M. |
Stable formulation of modified GLP-1
|
|
JP2005501058A
(ja)
|
2001-07-31 |
2005-01-13 |
ザ ガバメント オブ ザ ユナイテッドステイツ オブ アメリカ アズ リプレゼンテッド バイ ザ セクレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ ザ ナショナル インステ |
Glp−1、exendin−4、そのペプチド・アナログ及びその使用
|
|
US7176278B2
(en)
|
2001-08-30 |
2007-02-13 |
Biorexis Technology, Inc. |
Modified transferrin fusion proteins
|
|
US8129504B2
(en)
|
2001-08-30 |
2012-03-06 |
Biorexis Technology, Inc. |
Oral delivery of modified transferrin fusion proteins
|
|
PL205971B1
(pl)
|
2001-09-24 |
2010-06-30 |
Imp Innovations Ltd |
Zastosowanie PYY₃-₃₆ do wytwarzania leku na ograniczanie apetytu, zmniejszenie otyłości lub do zapobiegania otyłości
|
|
AU2002351752A1
(en)
|
2001-12-29 |
2003-07-30 |
Novo Nordisk A/S |
Combined use of a glp-1 compound and another drug for treating dyslipidemia
|
|
AU2003201998C1
(en)
|
2002-01-10 |
2012-10-25 |
Imperial Innovations Limited |
Modification of feeding behavior
|
|
US7105489B2
(en)
|
2002-01-22 |
2006-09-12 |
Amylin Pharmaceuticals, Inc. |
Methods and compositions for treating polycystic ovary syndrome
|
|
JP2005535569A
(ja)
*
|
2002-04-04 |
2005-11-24 |
ノボ・ノルデイスク・エー/エス |
Glp−1アゴニスト及び心臓血管合併症
|
|
ES2327328T3
(es)
|
2002-07-04 |
2009-10-28 |
Zealand Pharma A/S |
Glp-1 y procedimientos para el tratamiento de la diabetes.
|
|
JP2006501820A
(ja)
*
|
2002-09-06 |
2006-01-19 |
バイエル・フアーマシユーチカルズ・コーポレーシヨン |
修飾glp−1受容体アゴニストおよびそれらの薬理学的使用法
|
|
US7273921B2
(en)
|
2002-09-25 |
2007-09-25 |
Novo Nordisk A/S |
Method for producing acylated peptides
|
|
BR0314996A
(pt)
*
|
2002-10-02 |
2005-08-09 |
Zealand Pharma As |
Composição, composição farmaceuticamente aceitável, método para produzir a composição, métodos para estabilizar a exendina-4 (1-39) ou uma sua variante, derivado ou análogo contra a degradação, antes, durante ou após o uso pretendido, para tratar doenças, para tratar de estados de doenças associados com nìveis elevados de glicose do sangue, para a regulação dos nìveis de glicose do sangue, para a regulação do esvaziamento gástrico, para estimular a liberação de insulina em um mamìfero para reduzir o nìvel de glicose do sangue em um mamìfero, para reduzir o nìvel de lipìdeos plasmáticos em um mamìfero, para reduzir a mortalidade e a morbidez após o infarto miocárdico em um mamìfero, para estimular a liberação de insulina em um mamìfero, e para produzir uma exendina (1-39) estabilizada, e, exendina (1-39) estabilizada
|
|
KR20050049525A
(ko)
*
|
2002-10-11 |
2005-05-25 |
가부시키가이샤산와카가쿠켄큐쇼 |
Glp-1 유도체 및 그의 경점막 흡수형 제제
|
|
US6818721B2
(en)
|
2002-12-02 |
2004-11-16 |
Rpo Pty Ltd. |
Process for producing polysiloxanes and use of the same
|
|
EP1688148A1
(en)
*
|
2002-12-03 |
2006-08-09 |
Novo Nordisk A/S |
Combination treatment using exendin-4 and thiazolidinediones
|
|
AU2003283216A1
(en)
*
|
2002-12-03 |
2004-06-23 |
Novo Nordisk A/S |
Combination treatment using exendin-4 and thiazolidinediones
|
|
GB0300571D0
(en)
|
2003-01-10 |
2003-02-12 |
Imp College Innovations Ltd |
Modification of feeding behaviour
|
|
WO2004078777A2
(en)
*
|
2003-03-04 |
2004-09-16 |
Biorexis Pharmaceutical Corporation |
Dipeptidyl-peptidase protected proteins
|
|
DE10314610A1
(de)
|
2003-04-01 |
2004-11-04 |
Aventis Pharma Deutschland Gmbh |
Neues Diphenylazetidinon mit verbesserten physiologischen Eigenschaften, Verfahren zu dessen Herstellung, diese Verbindungen enthaltende Arzneimittel und dessen Verwendung
|
|
ES2425221T3
(es)
|
2003-05-30 |
2013-10-14 |
Amylin Pharmaceuticals, Llc |
Nuevos métodos y composiciones para suministro por vía transmucosa potenciado de péptidos y proteínas
|
|
US7094800B2
(en)
|
2003-07-25 |
2006-08-22 |
Sanofi-Aventis Deutschland Gmbh |
Cyanopyrrolidides, process for their preparation and their use as medicaments
|
|
US7008957B2
(en)
|
2003-07-25 |
2006-03-07 |
Sanofi-Aventis Deutschland Gmbh |
Bicyclic cyanoheterocycles, process for their preparation and their use as medicaments
|
|
US7094794B2
(en)
|
2003-07-28 |
2006-08-22 |
Sanofi-Aventis Deutschland Gmbh |
Substituted thiazole-benzoisothiazole dioxide derivatives, process for their preparation and their use
|
|
DE10335092B3
(de)
|
2003-08-01 |
2005-02-03 |
Aventis Pharma Deutschland Gmbh |
Substituierte Benzoylureido-o-benzoylamide, Verfahren zu deren Herstellung und deren Verwendung
|
|
KR101241862B1
(ko)
*
|
2003-09-19 |
2013-03-13 |
노보 노르디스크 에이/에스 |
신규 glp-1 유도체
|
|
RU2401276C2
(ru)
*
|
2003-09-19 |
2010-10-10 |
Ново Нордиск А/С |
Производные глюкагон-подобного пептида-1 (glp-1)
|
|
TW200522976A
(en)
|
2003-09-19 |
2005-07-16 |
Novo Nordisk As |
Novel plasma protein affinity tags
|
|
CN101380476A
(zh)
*
|
2003-09-19 |
2009-03-11 |
诺沃挪第克公司 |
治疗肽的清蛋白结合型衍生物
|
|
US20060287221A1
(en)
|
2003-11-13 |
2006-12-21 |
Novo Nordisk A/S |
Soluble pharmaceutical compositions for parenteral administration comprising a GLP-1 peptide and an insulin peptide of short time action for treatment of diabetes and bulimia
|
|
ES2373660T3
(es)
*
|
2003-11-13 |
2012-02-07 |
Novo Nordisk A/S |
Composición farmacéutica que comprende un análogo insulinotrópico de glp-1 (7-37), insulina asp(b28) y un tensioactivo.
|
|
PT1687019T
(pt)
|
2003-11-20 |
2018-02-26 |
Novo Nordisk As |
Formulações de péptidos que contêm polietileno glicol que são ótimas para produção e para utilização em dispositivos de injeção
|
|
WO2005056036A2
(en)
|
2003-12-09 |
2005-06-23 |
Novo Nordisk A/S |
Regulation of food preference using glp-1 agonists
|
|
US20080015144A1
(en)
*
|
2003-12-12 |
2008-01-17 |
Alvert Einstein College Of Medicine Of Yeshiva Uni |
Glp- (9-36) Methods and Compositions
|
|
JP2007537141A
(ja)
|
2003-12-18 |
2007-12-20 |
ノボ ノルディスク アクティーゼルスカブ |
新規なglp−1化合物
|
|
US20060094652A1
(en)
|
2004-02-11 |
2006-05-04 |
Levy Odile E |
Hybrid polypeptides with selectable properties
|
|
US8076288B2
(en)
|
2004-02-11 |
2011-12-13 |
Amylin Pharmaceuticals, Inc. |
Hybrid polypeptides having glucose lowering activity
|
|
CN1318587C
(zh)
*
|
2004-04-30 |
2007-05-30 |
成都芝田生物工程有限公司 |
酰胺化Exendin-4多肽的重组制备方法
|
|
EP1758575A1
(en)
|
2004-06-11 |
2007-03-07 |
Novo Nordisk A/S |
Counteracting drug-induced obesity using glp-1 agonists
|
|
AU2012202855B2
(en)
*
|
2004-09-03 |
2015-02-26 |
Philipps-Universitat Marburg |
GLP-1 and exendin related invention
|
|
DE102004043153B4
(de)
*
|
2004-09-03 |
2013-11-21 |
Philipps-Universität Marburg |
Erfindung betreffend GLP-1 und Exendin
|
|
JP2008515856A
(ja)
|
2004-10-07 |
2008-05-15 |
ノボ ノルディスク アクティーゼルスカブ |
遅延性glp−1化合物
|
|
EP2330126B1
(en)
*
|
2004-10-07 |
2015-12-23 |
Novo Nordisk A/S |
Protracted exendin-4 compounds
|
|
JP5248113B2
(ja)
*
|
2004-11-12 |
2013-07-31 |
ノヴォ ノルディスク アー/エス |
ペプチドの安定な処方
|
|
DE102004058306A1
(de)
*
|
2004-12-01 |
2006-07-27 |
Sanofi-Aventis Deutschland Gmbh |
Verfahren zur Herstellung von Carboxy-terminal amidierten Peptiden
|
|
US8716221B2
(en)
|
2005-01-14 |
2014-05-06 |
Wuxi Grandchamp Pharmaceutical Technology Co., Ltd. |
Modified exendins and uses thereof
|
|
CA2603630C
(en)
*
|
2005-01-14 |
2015-06-09 |
Wuxi Grandchamp Pharmaceutical Technology Co., Ltd. |
Modified exendins and uses thereof
|
|
BRPI0606992A2
(pt)
|
2005-02-11 |
2009-07-28 |
Amylin Pharmaceuticals Inc |
análogo e polipeptìdeos hìbridos de gip com propriedades selecionáveis
|
|
EP1858545A2
(en)
*
|
2005-03-04 |
2007-11-28 |
Curedm Inc. |
Methods and pharmaceutical compositions for treating type 1 diabetes mellitus and other conditions
|
|
WO2006097535A2
(en)
*
|
2005-03-18 |
2006-09-21 |
Novo Nordisk A/S |
Peptide agonists of the glucagon family with secretin like activity
|
|
TWI372629B
(en)
|
2005-03-18 |
2012-09-21 |
Novo Nordisk As |
Acylated glp-1 compounds
|
|
JP5755398B2
(ja)
*
|
2005-03-18 |
2015-07-29 |
ノヴォ ノルディスク アー/エス |
伸長されたglp−1化合物
|
|
MX2007013431A
(es)
|
2005-05-04 |
2008-01-18 |
Zealand Pharma As |
Analogos del peptido 2 semejante al glucagon.
|
|
EA013821B1
(ru)
|
2005-05-25 |
2010-08-30 |
Кьюрдм, Инк. |
Проостровковые пептиды человека, их производные и аналоги и способы их применения
|
|
BRPI0614649A2
(pt)
|
2005-08-11 |
2011-04-12 |
Amylin Pharmaceuticals Inc |
polipeptìdeos hìbridos com propriedades selecionáveis
|
|
AU2006279680B2
(en)
|
2005-08-11 |
2012-12-06 |
Amylin Pharmaceuticals, Llc |
Hybrid polypeptides with selectable properties
|
|
AU2005335905C1
(en)
|
2005-08-26 |
2011-12-22 |
Abbvie Inc. |
Therapeutically active alpha-MSH analogues
|
|
US8178495B2
(en)
|
2008-06-27 |
2012-05-15 |
Duke University |
Therapeutic agents comprising a GLP-1 receptor agonist and elastin-like peptide
|
|
DE102006031955A1
(de)
|
2006-07-11 |
2008-01-17 |
Sanofi-Aventis Deutschland Gmbh |
Verfahren zur Herstellung von Insulinanaloga mit dibasischem B-Kettenende
|
|
DE102006031962A1
(de)
|
2006-07-11 |
2008-01-17 |
Sanofi-Aventis Deutschland Gmbh |
Amidiertes Insulin Glargin
|
|
KR101193722B1
(ko)
|
2006-07-24 |
2013-01-11 |
바이오렉시스 파마슈티칼 코포레이션 |
엑센딘 융합 단백질
|
|
BRPI0715160A2
(pt)
|
2006-08-08 |
2013-06-11 |
Sanofi Aventis |
imidazolidina-2,4-dionas substituÍdas por arilamimoaril-alquil-, processo para preparÁ-las, medicamentos compeendendo estes compostos, e seu uso
|
|
UA100497C2
(ru)
|
2006-09-07 |
2013-01-10 |
Никомед Гмбх |
Комбинированное лечение сахарного диабета
|
|
AU2007319066B2
(en)
|
2006-11-08 |
2013-09-19 |
Zealand Pharma A/S |
Selective glucagon-like-peptide-2 (GLP-2) analogues
|
|
JP2010043001A
(ja)
*
|
2006-11-09 |
2010-02-25 |
Sanwa Kagaku Kenkyusho Co Ltd |
Glp−1誘導体とその用途
|
|
WO2008064306A2
(en)
|
2006-11-22 |
2008-05-29 |
Curedm, Inc. |
Methods and compositions relating to islet cell neogenesis
|
|
TWI428346B
(zh)
|
2006-12-13 |
2014-03-01 |
Imp Innovations Ltd |
新穎化合物及其等對進食行為影響
|
|
RU2413528C2
(ru)
|
2007-01-18 |
2011-03-10 |
Открытое Акционерное Общество "Валента Фармацевтика" |
Лекарственный препарат для лечения сахарного диабета на основе экзенатида и даларгина, применение и способ лечения
|
|
DE102007005045B4
(de)
|
2007-01-26 |
2008-12-18 |
Sanofi-Aventis |
Phenothiazin Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
WO2008098693A2
(en)
*
|
2007-02-16 |
2008-08-21 |
Bayer Healthcare Ag |
Convergent synthesis of glp-1
|
|
KR101560844B1
(ko)
|
2007-06-04 |
2015-10-15 |
벤-구리온 유니버시티 오브 더 네게브 리서치 앤드 디벨럽먼트 어쏘러티 |
트라이-아릴계 화합물 및 이를 포함하는 조성물
|
|
JP5385266B2
(ja)
|
2007-06-15 |
2014-01-08 |
ジーランド ファーマ アクティーゼルスカブ |
グルカゴン類似体
|
|
EP2025674A1
(de)
|
2007-08-15 |
2009-02-18 |
sanofi-aventis |
Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
ES2534434T3
(es)
|
2007-08-30 |
2015-04-22 |
Curedm Group Holdings, Llc |
Composiciones y métodos de uso de péptidos proislotes y análogos de los mismos
|
|
ES2672770T3
(es)
*
|
2007-09-05 |
2018-06-18 |
Novo Nordisk A/S |
Derivados del péptido-1 similar al glucagón y su uso farmacéutico
|
|
WO2009030774A1
(en)
|
2007-09-05 |
2009-03-12 |
Novo Nordisk A/S |
Truncated glp-1 derivatives and their therapeutical use
|
|
JP5473925B2
(ja)
*
|
2007-10-27 |
2014-04-16 |
コーデン ファーマ コロラド インコーポレイテッド |
固相および溶液相の組み合わせ技法を使用するインスリン分泌性ペプチドの合成
|
|
DE102007054497B3
(de)
|
2007-11-13 |
2009-07-23 |
Sanofi-Aventis Deutschland Gmbh |
Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung
|
|
WO2009063072A2
(en)
|
2007-11-16 |
2009-05-22 |
Novo Nordisk A/S |
Pharmaceutical compositions containing insulin and an insulinotropic peptide
|
|
BRPI0907119A2
(pt)
|
2008-01-09 |
2015-07-14 |
Sanofi Aventis Deutschland |
Derivados de insulina tendo um perfil de ação de tempo extremamente retardado
|
|
DE102008025008A1
(de)
|
2008-05-24 |
2009-11-26 |
Sanofi-Aventis Deutschland Gmbh |
Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
|
|
DE102008025007A1
(de)
|
2008-05-24 |
2009-11-26 |
Sanofi-Aventis Deutschland Gmbh |
Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
|
|
DE102008003568A1
(de)
|
2008-01-09 |
2009-07-16 |
Sanofi-Aventis Deutschland Gmbh |
Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
|
|
AU2009203809B2
(en)
|
2008-01-09 |
2013-07-25 |
Sanofi-Aventis Deutschland Gmbh |
Novel insulin derivatives having an extremely delayed time-action profile
|
|
DE102008003566A1
(de)
|
2008-01-09 |
2009-07-16 |
Sanofi-Aventis Deutschland Gmbh |
Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
|
|
TWI474835B
(zh)
*
|
2008-06-17 |
2015-03-01 |
Univ Indiana Res & Tech Corp |
用於治療代謝病症及肥胖症之基於gip之混合激動劑
|
|
WO2010003624A2
(en)
|
2008-07-09 |
2010-01-14 |
Sanofi-Aventis |
Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
|
|
AU2009279090A1
(en)
|
2008-08-06 |
2010-02-11 |
Novo Nordisk Health Care Ag |
Conjugated proteins with prolonged in vivo efficacy
|
|
DE102009038210A1
(de)
|
2009-08-20 |
2011-03-03 |
Sanofi-Aventis Deutschland Gmbh |
Kombination von einem Insulin und einem GLP-1-Agonisten
|
|
DE102008053048A1
(de)
|
2008-10-24 |
2010-04-29 |
Sanofi-Aventis Deutschland Gmbh |
Kombination von einem Insulin und einem GLP-1-Agonisten
|
|
DE102008051834A1
(de)
|
2008-10-17 |
2010-04-22 |
Sanofi-Aventis Deutschland Gmbh |
Kombination von einem Insulin und einem GLP-1-Agonisten
|
|
PT3228320T
(pt)
|
2008-10-17 |
2020-03-26 |
Sanofi Aventis Deutschland |
Combinação de uma insulina e de um agonista do glp-1
|
|
WO2010054326A2
(en)
|
2008-11-07 |
2010-05-14 |
The General Hospital Corporation |
C-terminal fragments of glucagon-like peptide-1 (glp-1)
|
|
WO2010068601A1
(en)
|
2008-12-08 |
2010-06-17 |
Sanofi-Aventis |
A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
|
|
DK2373681T3
(da)
*
|
2008-12-10 |
2017-04-24 |
Glaxosmithkline Llc |
Farmaceutiske sammensætninger af albiglutid
|
|
MX2011006314A
(es)
|
2008-12-15 |
2011-09-22 |
Zealand Pharma As |
Analogos de glucagon.
|
|
PL2370462T3
(pl)
|
2008-12-15 |
2015-01-30 |
Zealand Pharma As |
Analogi glukagonu
|
|
AU2008365557A1
(en)
|
2008-12-15 |
2011-07-21 |
Zealand Pharma A/S |
Glucagon analogues
|
|
EA020537B1
(ru)
|
2008-12-15 |
2014-11-28 |
Зилэнд Фарма А/С |
Аналоги глюкагона
|
|
CA2747825A1
(en)
|
2009-01-22 |
2010-07-29 |
Novo Nordisk Health Care Ag |
Stable growth hormone compounds
|
|
KR101853606B1
(ko)
|
2009-07-06 |
2018-05-03 |
사노피-아벤티스 도이칠란트 게엠베하 |
메티오닌을 함유하는 수성 인슐린 제제
|
|
JP5675799B2
(ja)
*
|
2009-07-06 |
2015-02-25 |
サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング |
遅効性インスリン製剤
|
|
AP3329A
(en)
|
2009-07-13 |
2015-06-30 |
Zealand Pharma As |
Acylated glucagon analogues
|
|
CN101987868B
(zh)
*
|
2009-07-30 |
2013-09-04 |
江苏豪森医药集团有限公司 |
Glp-1类似物的衍生物或其可药用盐和用途
|
|
EP2461831B1
(en)
|
2009-08-06 |
2018-11-21 |
Novo Nordisk Health Care AG |
Growth hormones with prolonged in-vivo efficacy
|
|
DK2470552T3
(da)
|
2009-08-26 |
2014-02-17 |
Sanofi Sa |
Hidtil ukendte, krystallinske, heteroaromatiske fluorglycosidhydrater, lægemidler, der omfatter disse forbindelser, og deres anvendelse
|
|
US20120264685A1
(en)
|
2009-10-22 |
2012-10-18 |
Rajesh Bahekar |
Short chain peptidomimetics based orally active glp 1 agonist and glucagon receptor antagonist
|
|
JP2011105609A
(ja)
*
|
2009-11-13 |
2011-06-02 |
Sanofi-Aventis Deutschland Gmbh |
メトホルミンへの付加療法を含む2型糖尿病の治療方法
|
|
PL2324853T3
(pl)
|
2009-11-13 |
2016-01-29 |
Sanofi Aventis Deutschland |
Liksysenatyd jako dodatek do metforminy w leczeniu cukrzycy typu 2
|
|
DE102010011919A1
(de)
|
2010-03-18 |
2011-09-22 |
Sanofi-Aventis Deutschland Gmbh |
Pharmazeutische Zusammensetzung umfassend einen GLP-1-Agonisten und Methionin
|
|
AU2009238272B2
(en)
*
|
2009-11-13 |
2014-05-08 |
Sanofi-Aventis Deutschland Gmbh |
Method of treatment of diabetes type 2 comprising add-on therapy to metformin
|
|
KR101337322B1
(ko)
|
2009-11-13 |
2013-12-06 |
사노피-아벤티스 도이칠란트 게엠베하 |
Glp-1 효능제 및 메티오닌을 포함하는 약제학적 조성물
|
|
ME01546B
(me)
|
2009-11-13 |
2014-04-20 |
Sanofi Aventis Deutschland |
Liksisenatid kao dodatna terapija insulin glarginu i metforminu za liječenje dijabetesa tipa 2
|
|
DK2498802T3
(da)
|
2009-11-13 |
2015-04-13 |
Sanofi Aventis Deutschland |
Farmaceutisk præparat omfattende en glp-1-agonist, et insulin og en methionin
|
|
EA026384B1
(ru)
|
2010-01-20 |
2017-04-28 |
Зилэнд Фарма А/С |
Лечение заболеваний сердца
|
|
RU2012134974A
(ru)
|
2010-01-22 |
2014-02-27 |
Ново Нордиск Хелс Кеа Аг |
Стабилизированное соединение гормона роста
|
|
RU2605627C2
(ru)
|
2010-01-22 |
2016-12-27 |
Ново Нордиск Хелс Кеа Аг |
Гормоны роста с пролонгированной эффективностью in vivo
|
|
CN102770440A
(zh)
|
2010-03-01 |
2012-11-07 |
诺沃—诺迪斯克有限公司 |
纯化肽的制备性rp-hplc方法
|
|
WO2011107494A1
(de)
|
2010-03-03 |
2011-09-09 |
Sanofi |
Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
US9168288B2
(en)
|
2010-04-09 |
2015-10-27 |
Mount Sinai Hospital |
Methods for treating disorders of the gastrointestinal tract using a GLP-1 agonist
|
|
DE102010015123A1
(de)
|
2010-04-16 |
2011-10-20 |
Sanofi-Aventis Deutschland Gmbh |
Benzylamidische Diphenylazetidinone, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
|
|
CA2797133C
(en)
|
2010-04-27 |
2019-08-06 |
Zealand Pharma A/S |
Peptide conjugates of glp-1 receptor agonists and gastrin and their use
|
|
JP2013525491A
(ja)
|
2010-05-04 |
2013-06-20 |
グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー |
心血管障害を治療または予防し心血管保護を提供する方法
|
|
AU2011202239C1
(en)
|
2010-05-19 |
2017-03-16 |
Sanofi |
Long-acting formulations of insulins
|
|
EP2389945A1
(en)
|
2010-05-28 |
2011-11-30 |
Sanofi-Aventis Deutschland GmbH |
Pharmaceutical composition comprising AVE0010 and insulin glargine
|
|
CN101891823B
(zh)
*
|
2010-06-11 |
2012-10-03 |
北京东方百泰生物科技有限公司 |
一种Exendin-4及其类似物融合蛋白
|
|
US8933024B2
(en)
|
2010-06-18 |
2015-01-13 |
Sanofi |
Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
|
|
US8530413B2
(en)
|
2010-06-21 |
2013-09-10 |
Sanofi |
Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
|
|
UY33462A
(es)
|
2010-06-23 |
2012-01-31 |
Zealand Pharma As |
Analogos de glucagon
|
|
KR20130086343A
(ko)
|
2010-06-24 |
2013-08-01 |
질랜드 파마 에이/에스 |
글루카곤 유사체
|
|
TW201221505A
(en)
|
2010-07-05 |
2012-06-01 |
Sanofi Sa |
Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
|
|
TW201215388A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Sa |
(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
|
|
TW201215387A
(en)
|
2010-07-05 |
2012-04-16 |
Sanofi Aventis |
Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
|
|
ES2606554T3
(es)
|
2010-08-30 |
2017-03-24 |
Sanofi-Aventis Deutschland Gmbh |
Uso de AVE0010 para la fabricación de un medicamento para el tratamiento de la diabetes mellitus de tipo 2
|
|
US9040481B2
(en)
|
2010-11-02 |
2015-05-26 |
The General Hospital Corporation |
Methods for treating steatotic disease
|
|
PL2651398T3
(pl)
|
2010-12-16 |
2018-05-30 |
Novo Nordisk A/S |
Stałe kompozycje zawierające agonistę GLP-1 i sól kwasu N-(8-(2-hydroksybenzoilo)amino)kaprylowego
|
|
RU2572703C2
(ru)
|
2011-02-02 |
2016-01-20 |
Санофи-Авентис Дойчланд Гмбх |
Предотвращение гипогликемии у пациентов с сахарным диабетом 2 типа
|
|
WO2012120056A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
WO2012120050A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
US8809325B2
(en)
|
2011-03-08 |
2014-08-19 |
Sanofi |
Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof
|
|
EP2683703B1
(de)
|
2011-03-08 |
2015-05-27 |
Sanofi |
Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
WO2012120054A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
EP2766349B1
(de)
|
2011-03-08 |
2016-06-01 |
Sanofi |
Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
WO2012120058A1
(de)
|
2011-03-08 |
2012-09-13 |
Sanofi |
Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
US8710050B2
(en)
|
2011-03-08 |
2014-04-29 |
Sanofi |
Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
|
|
EP2683704B1
(de)
|
2011-03-08 |
2014-12-17 |
Sanofi |
Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
|
|
US20120277147A1
(en)
|
2011-03-29 |
2012-11-01 |
Sanofi-Aventis Deutschland Gmbh |
Prevention of hypoglycaemia in diabetes mellitus type 2 patients
|
|
DK2696687T3
(da)
|
2011-04-12 |
2017-02-06 |
Novo Nordisk As |
Dobbeltacylerede GLP-1 derivater
|
|
US20130040878A1
(en)
|
2011-05-13 |
2013-02-14 |
Sanofi-Aventis Deutschland Gmbh |
Pharmaceutical combination for use in the treatment of diabetes type 2 patients
|
|
US9821032B2
(en)
|
2011-05-13 |
2017-11-21 |
Sanofi-Aventis Deutschland Gmbh |
Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
|
|
ES2556466T3
(es)
|
2011-05-13 |
2016-01-18 |
Sanofi-Aventis Deutschland Gmbh |
Lixisenatida y metformina para el tratamiento de la diabetes tipo 2
|
|
US8735349B2
(en)
|
2011-05-13 |
2014-05-27 |
Sanofi-Aventis Deutschland Gmbh |
Method for improving glucose tolerance in a diabetes type 2 patient of younger than 50 years and having postprandial plasma glucose concentration of at least 14 mmol/L
|
|
EP2729157B1
(en)
|
2011-07-06 |
2019-01-16 |
The General Hospital Corporation |
A pentapeptide derived from the c-terminus of glucagon-like peptide 1 (glp-1) for use in treatment
|
|
PL2750699T3
(pl)
|
2011-08-29 |
2015-12-31 |
Sanofi Aventis Deutschland |
Kombinacja farmaceutyczna do stosowania w kontroli glikemii u pacjentów z cukrzycą typu 2
|
|
AR087744A1
(es)
|
2011-09-01 |
2014-04-16 |
Sanofi Aventis Deutschland |
Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
|
|
WO2013037390A1
(en)
|
2011-09-12 |
2013-03-21 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
EP2567959B1
(en)
|
2011-09-12 |
2014-04-16 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
WO2013045413A1
(en)
|
2011-09-27 |
2013-04-04 |
Sanofi |
6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
US20130096059A1
(en)
|
2011-10-04 |
2013-04-18 |
Jens Stechl |
Glp-1 agonist for use in the treatment of stenosis or/and obstruction in the biliary tract
|
|
HUE028568T2
(en)
|
2011-10-04 |
2016-12-28 |
Sanofi Aventis Deutschland |
For use in the treatment of constriction and / or obstruction of the lysine senate and pancreatic duct system
|
|
MY170713A
(en)
|
2011-10-28 |
2019-08-27 |
Sanofi Aventis Deutschland |
Treatment protocol of diabetes type 2
|
|
CN103087174B
(zh)
*
|
2011-11-03 |
2015-11-18 |
华东师范大学 |
一种glp-1衍生物dlg3312及其固相化学合成方法
|
|
TW201326194A
(zh)
|
2011-11-03 |
2013-07-01 |
Zealand Pharma As |
Glp-1胃泌素受體促效劑肽結合物
|
|
CN104244981A
(zh)
|
2011-12-09 |
2014-12-24 |
诺和诺德A/S |
Glp-1激动剂
|
|
KR20140114845A
(ko)
|
2011-12-23 |
2014-09-29 |
질랜드 파마 에이/에스 |
글루카곤 유사체
|
|
EP4324475A1
(en)
|
2012-03-22 |
2024-02-21 |
Novo Nordisk A/S |
Compositions of glp-1 peptides and preparation thereof
|
|
HUE042757T2
(hu)
|
2012-03-22 |
2019-07-29 |
Novo Nordisk As |
Szállító szert tartalmazó készítmények és elõállításuk
|
|
NZ702333A
(en)
|
2012-05-03 |
2017-06-30 |
Zealand Pharma As |
Gip-glp-1 dual agonist compounds and methods
|
|
TR201802689T4
(tr)
|
2012-05-03 |
2018-03-21 |
Zealand Pharma As |
Glukagon benzeri peptit-2 (glp-2) analogları.
|
|
JP6517690B2
(ja)
|
2012-06-20 |
2019-05-22 |
ノヴォ ノルディスク アー/エス |
ペプチド及び送達剤を含む錠剤製剤
|
|
MX356957B
(es)
|
2012-07-23 |
2018-06-20 |
Zealand Pharma As |
Analogos del glucagon.
|
|
TWI608013B
(zh)
|
2012-09-17 |
2017-12-11 |
西蘭製藥公司 |
升糖素類似物
|
|
WO2014064215A1
(en)
|
2012-10-24 |
2014-05-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
TPL2 KINASE INHIBITORS FOR PREVENTING OR TREATING DIABETES AND FOR PROMOTING β-CELL SURVIVAL
|
|
WO2014077575A1
(ko)
*
|
2012-11-13 |
2014-05-22 |
다인바이오 주식회사 |
덱에이 효소반응으로 조제한 항비만 및 항당뇨 효능을 갖는 한천 유래 네오아가로올리고당 복합 조성물
|
|
KR20140088837A
(ko)
*
|
2013-01-03 |
2014-07-11 |
한미약품 주식회사 |
N-말단 전하가 변형된 인슐린 분비 펩티드 유도체
|
|
TWI641381B
(zh)
|
2013-02-04 |
2018-11-21 |
法商賽諾菲公司 |
胰島素類似物及/或胰島素衍生物之穩定化醫藥調配物
|
|
MX369511B
(es)
|
2013-04-03 |
2019-11-11 |
Sanofi Sa |
Tratamiento de la diabetes mellitus mediante formulaciones de insulinas de acción prolongada.
|
|
EP2981282B1
(en)
|
2013-04-05 |
2020-11-04 |
Novo Nordisk Health Care AG |
Growth hormone compound formulation
|
|
KR20210086717A
(ko)
|
2013-05-02 |
2021-07-08 |
노보 노르디스크 에이/에스 |
Glp-1 화합물의 경구 투여
|
|
BR112015032875A2
(pt)
|
2013-07-04 |
2017-11-07 |
Novo Nordisk As |
derivados de peptídeos do tipo glp-1, e usos dos mesmos
|
|
GB201315335D0
(en)
*
|
2013-08-29 |
2013-10-09 |
Of Singapore |
Amino diacids containing peptide modifiers
|
|
US9988429B2
(en)
|
2013-10-17 |
2018-06-05 |
Zealand Pharma A/S |
Glucagon analogues
|
|
LT3057984T
(lt)
|
2013-10-17 |
2018-12-27 |
Zealand Pharma A/S |
Acilinti gliukagono analogai
|
|
EA201690938A1
(ru)
|
2013-11-05 |
2016-11-30 |
Бен-Гурион Юниверсити Оф Дзе Негев Рисерч Энд Дивелопмент Оторити |
Соединения для лечения диабета и осложнений, возникающих из-за этого заболевания
|
|
AU2014345569B2
(en)
|
2013-11-06 |
2020-08-13 |
Zealand Pharma A/S |
GIP-GLP-1 dual agonist compounds and methods
|
|
KR102310392B1
(ko)
|
2013-11-06 |
2021-10-13 |
질랜드 파마 에이/에스 |
글루카곤-glp-1-gip 삼원 효능제 화합물
|
|
CN103613657B
(zh)
*
|
2013-11-28 |
2016-01-13 |
孙玉琨 |
缩短肽链的Exendin4及其基因工程应用
|
|
SG11201604706TA
(en)
|
2014-01-09 |
2016-07-28 |
Sanofi Sa |
Stabilized pharmaceutical formulations of insulin aspart
|
|
CN112957455A
(zh)
|
2014-01-09 |
2021-06-15 |
赛诺菲 |
胰岛素类似物和/或胰岛素衍生物的稳定化药物制剂
|
|
EP3091965A1
(en)
|
2014-01-09 |
2016-11-16 |
Sanofi |
Stabilized glycerol free pharmaceutical formulations of insulin analogues and/or insulin derivatives
|
|
KR101768446B1
(ko)
*
|
2014-03-21 |
2017-08-17 |
애니젠 주식회사 |
신규한 엑세나타이드 유사체 및 그의 용도
|
|
RU2716985C2
(ru)
|
2014-10-29 |
2020-03-17 |
Зилэнд Фарма А/С |
Соединения-агонисты gip и способы
|
|
AU2015359376B2
(en)
|
2014-12-12 |
2021-09-09 |
Sanofi-Aventis Deutschland Gmbh |
Insulin glargine/lixisenatide fixed ratio formulation
|
|
TWI706779B
(zh)
|
2015-01-16 |
2020-10-11 |
德商賽諾菲阿凡提斯德意志有限公司 |
小兒第2型糖尿病病患之治療
|
|
TWI748945B
(zh)
|
2015-03-13 |
2021-12-11 |
德商賽諾菲阿凡提斯德意志有限公司 |
第2型糖尿病病患治療
|
|
TW201705975A
(zh)
|
2015-03-18 |
2017-02-16 |
賽諾菲阿凡提斯德意志有限公司 |
第2型糖尿病病患之治療
|
|
WO2016151018A1
(en)
|
2015-03-24 |
2016-09-29 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method and pharmaceutical composition for use in the treatment of diabetes
|
|
JP6989385B2
(ja)
|
2015-04-16 |
2022-01-05 |
ジーランド ファーマ アクティーゼルスカブ |
アシル化グルカゴン類似体
|
|
SG10201911851VA
(en)
|
2016-12-09 |
2020-02-27 |
Zealand Pharma As |
Acylated glp-1/glp-2 dual agonists
|
|
ES2894629T3
(es)
|
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|
|
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(pl)
|
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|
|
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(fr)
|
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|
|
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(hu)
|
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|
|
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(en)
|
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2019-08-08 |
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|
|
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(zh)
|
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|
|
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(en)
|
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|
|
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(fr)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(zh)
*
|
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|
|
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(zh)
*
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(es)
|
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|
|
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|
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|
|
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|
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|
|
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(en)
*
|
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|
|
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|
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|
|
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|
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|
|
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|
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|
|
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|
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|
|
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|
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|
|
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|
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|
|
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|
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|
|
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|
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|
|
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|
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|