IL147328A0 - Respiratory syncytial virus replication inhibitors - Google Patents

Respiratory syncytial virus replication inhibitors

Info

Publication number
IL147328A0
IL147328A0 IL14732800A IL14732800A IL147328A0 IL 147328 A0 IL147328 A0 IL 147328A0 IL 14732800 A IL14732800 A IL 14732800A IL 14732800 A IL14732800 A IL 14732800A IL 147328 A0 IL147328 A0 IL 147328A0
Authority
IL
Israel
Prior art keywords
respiratory syncytial
syncytial virus
virus replication
replication inhibitors
inhibitors
Prior art date
Application number
IL14732800A
Other languages
English (en)
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of IL147328A0 publication Critical patent/IL147328A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL14732800A 1999-06-28 2000-06-20 Respiratory syncytial virus replication inhibitors IL147328A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99202089 1999-06-28
PCT/EP2000/005677 WO2001000615A1 (fr) 1999-06-28 2000-06-20 Inhibiteurs de réplication de virus syncytiaux respiratoires

Publications (1)

Publication Number Publication Date
IL147328A0 true IL147328A0 (en) 2002-08-14

Family

ID=8240374

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14732800A IL147328A0 (en) 1999-06-28 2000-06-20 Respiratory syncytial virus replication inhibitors
IL147328A IL147328A (en) 1999-06-28 2001-12-26 Benzimidazole and imidazopyridine compounds and their use in the preparation of drugs for the treatment or prevention of viral infections

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL147328A IL147328A (en) 1999-06-28 2001-12-26 Benzimidazole and imidazopyridine compounds and their use in the preparation of drugs for the treatment or prevention of viral infections

Country Status (34)

Country Link
US (2) US7071192B1 (fr)
EP (2) EP1400519B1 (fr)
JP (1) JP2003503403A (fr)
KR (1) KR100731273B1 (fr)
CN (1) CN1171887C (fr)
AR (1) AR024495A1 (fr)
AT (2) ATE259796T1 (fr)
AU (1) AU774829B2 (fr)
BG (1) BG65373B1 (fr)
BR (1) BR0011997A (fr)
CA (1) CA2376785A1 (fr)
CZ (1) CZ20014573A3 (fr)
DE (2) DE60008382T2 (fr)
DK (1) DK1196410T3 (fr)
EA (1) EA004746B1 (fr)
EE (1) EE04592B1 (fr)
ES (2) ES2215670T3 (fr)
HK (1) HK1045998B (fr)
HR (2) HRP20080390A2 (fr)
HU (1) HUP0201789A3 (fr)
IL (2) IL147328A0 (fr)
MX (1) MXPA02000117A (fr)
MY (1) MY129810A (fr)
NO (1) NO321599B1 (fr)
NZ (1) NZ515392A (fr)
PL (1) PL200694B1 (fr)
PT (1) PT1196410E (fr)
SI (1) SI1196410T1 (fr)
SK (1) SK18952001A3 (fr)
TR (2) TR200103805T2 (fr)
TW (1) TWI267513B (fr)
UA (1) UA75866C2 (fr)
WO (1) WO2001000615A1 (fr)
ZA (1) ZA200110473B (fr)

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US6495580B1 (en) 1998-01-29 2002-12-17 Viropharma Incorporated Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
HUP0103256A3 (en) 1998-07-15 2002-05-28 Teijin Ltd Thiobenzimidazole derivatives and pharmaceutical compositions containing the compounds
US20040010004A1 (en) 2000-01-17 2004-01-15 Naoki Tsuchiya Benzimidazole derivatives
PT1249450E (pt) * 2000-01-17 2008-01-02 Teijin Pharma Ltd Derivados de benzimidazole como inibidores de quimase humana
US6489338B2 (en) 2000-06-13 2002-12-03 Bristol-Myers Squibb Company Imidazopyridine and imidazopyrimidine antiviral agents
PE20020506A1 (es) 2000-08-22 2002-07-09 Glaxo Group Ltd Derivados de pirazol fusionados como inhibidores de la proteina cinasa
US6506738B1 (en) 2000-09-27 2003-01-14 Bristol-Myers Squibb Company Benzimidazolone antiviral agents
WO2002048148A2 (fr) 2000-12-15 2002-06-20 Glaxo Group Limited Composes therapeutiques
ATE301653T1 (de) 2000-12-15 2005-08-15 Glaxo Group Ltd Pyrazolopyridine
US6774134B2 (en) 2000-12-20 2004-08-10 Bristol-Myers Squibb Company Heterocyclic substituted 2-methyl-benzimidazole antiviral agents
DE60201074T2 (de) 2001-03-08 2005-09-15 Smithkline Beecham Corp. Pyrazolopyridinderivate
EP1372643A1 (fr) 2001-03-30 2004-01-02 Smithkline Beecham Corporation Pyralopyridines, leur procede de preparation et leur utilisation en tant que composes therapeutiques
US7141569B2 (en) 2001-04-10 2006-11-28 Smithkline Beecham Corporation Antiviral pyrazolopyridine compounds
ES2242028T3 (es) 2001-04-27 2005-11-01 Smithkline Beecham Corporation Derivados de pirazolo(1,5-a)piridina.
US7030150B2 (en) 2001-05-11 2006-04-18 Trimeris, Inc. Benzimidazole compounds and antiviral uses thereof
HUP0400266A2 (hu) 2001-06-21 2004-08-30 Smithkline Beecham Corp. Imidazo[1,2-a]piridin-származékok, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk herpeszvírus-fertőzések megelőzésére vagy kezelésére
WO2003031446A1 (fr) * 2001-10-05 2003-04-17 Smithkline Beecham Corporation Derives imidazo-pyridine destines au traitement d'infection virale herpetique
US6919331B2 (en) 2001-12-10 2005-07-19 Bristol-Myers Squibb Company Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents
AU2002357740A1 (en) 2001-12-11 2003-06-23 Smithkline Beecham Corporation Pyrazolo-pyridine derivatives as antiherpes agents
US7244847B2 (en) * 2002-02-06 2007-07-17 Isis Pharmaceuticals, Inc. Benzimidazole compounds
WO2004014317A2 (fr) 2002-08-09 2004-02-19 Viropharma Incorporated Composes, compositions et methodes de traitement ou de prevention d'infections pneumovirales et de maladies connexes
AU2003258176A1 (en) 2002-08-09 2004-02-25 Viropharma Incorporated Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
JP2006504728A (ja) 2002-10-03 2006-02-09 スミスクライン ビーチャム コーポレーション ピラソロピリジン誘導体系治療用化合物
US7323567B2 (en) 2003-10-30 2008-01-29 Boehringer Ingelheim (Canada) Ltd. RSV polymerase inhibitors
AR046972A1 (es) * 2003-12-18 2006-01-04 Tibotec Pharm Ltd Derivados de los amino-bencimidazoles como inhibidores de la replicacion del virus sincitial respiratorio
MY142783A (en) * 2003-12-18 2010-12-31 Tibotec Pharm Ltd 5-or 6-substituted benzimidazole derivatives as inhibitors of respiratory syncytial virus replication
AR046959A1 (es) * 2003-12-18 2006-01-04 Tibotec Pharm Ltd Morfolinilo que contiene bencimidazoles como inhibidores de la replicacion del virus sincitial respiratorio
CN103450159A (zh) 2003-12-18 2013-12-18 泰博特克药品有限公司 作为呼吸道合胞病毒复制的抑制剂的哌啶-氨基-苯并咪唑类衍生物
JP2007514718A (ja) * 2003-12-18 2007-06-07 テイボテク・フアーマシユーチカルズ・リミテツド 呼吸器シンシチウムウイルス複製のインヒビターとしてのアミノ−ベンズイミダゾール誘導体
TWI356055B (en) * 2003-12-18 2012-01-11 Tibotec Pharm Ltd Aminobenzimidazoles and benzimidazoles as inhibito
MX2007011292A (es) * 2005-03-17 2007-11-07 Tibotec Pharm Ltd 1,3-dihidro-bencimidazol-2-ilidenaminas como inhibidores de replicacion de virus respiratorios sinciciales.
WO2006136562A1 (fr) 2005-06-20 2006-12-28 Tibotec Pharmaceuticals Ltd Benzimidazoles substitués par un hétérocyclylaminoalkyle
US7884215B2 (en) * 2005-06-20 2011-02-08 Bonfanti Jean-Francois 2-substituted benzimidazoles
MX2007016537A (es) * 2005-06-20 2008-03-06 Tibotec Pharm Ltd 1,3-dihidro-benzoimidazol-onas 1-(2-amino-3-(alquilo sustituido)-3h-bencimidazolilmetil)-3-sustituidas con actividad sobre virus respiratorios sinciciales.
CL2008001003A1 (es) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
WO2010045276A2 (fr) * 2008-10-16 2010-04-22 Cara Therapeutics, Inc. Azabenzimidazolones
JP5487692B2 (ja) 2009-04-10 2014-05-07 国立大学法人京都大学 複素環骨格を有する化合物および該化合物を不斉触媒として用いる光学活性化合物の製造方法
KR20120049852A (ko) * 2009-06-30 2012-05-17 시가 테크놀로지스, 인크. 뎅기 바이러스 감염의 치료 및 예방
US8993604B2 (en) 2009-06-30 2015-03-31 Siga Technologies, Inc. Treatment and prevention of dengue virus infections
WO2013011932A1 (fr) 2011-07-15 2013-01-24 塩野義製薬株式会社 Dérivé d'azabenzimidazole possédant une activité activant l'ampk
US9724351B2 (en) * 2012-08-23 2017-08-08 Alios Biopharma, Inc. Compounds for the treatment of paramoxyvirus viral infections
JP2016079168A (ja) 2014-10-17 2016-05-16 塩野義製薬株式会社 ９員縮合環誘導体

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Also Published As

Publication number Publication date
HRP20080390A2 (en) 2008-12-31
KR20020000815A (ko) 2002-01-05
EE200100694A (et) 2003-02-17
EP1400519B1 (fr) 2007-03-07
PL200694B1 (pl) 2009-01-30
NO20016370D0 (no) 2001-12-27
TR200500707T2 (tr) 2005-04-21
BG65373B1 (bg) 2008-04-30
HUP0201789A3 (en) 2003-12-29
DE60033859D1 (de) 2007-04-19
WO2001000615A1 (fr) 2001-01-04
EP1400519A1 (fr) 2004-03-24
SK18952001A3 (sk) 2002-11-06
JP2003503403A (ja) 2003-01-28
ES2283716T3 (es) 2007-11-01
CN1171887C (zh) 2004-10-20
WO2001000615A8 (fr) 2002-01-10
AU774829B2 (en) 2004-07-08
MY129810A (en) 2007-05-31
AR024495A1 (es) 2002-10-02
IL147328A (en) 2007-06-03
ATE356121T1 (de) 2007-03-15
DE60008382T2 (de) 2004-12-02
CA2376785A1 (fr) 2001-01-04
NO20016370L (no) 2001-12-27
SI1196410T1 (en) 2004-08-31
NZ515392A (en) 2004-03-26
AU5222200A (en) 2001-01-31
HK1045998B (zh) 2005-06-03
UA75866C2 (en) 2006-06-15
DE60008382D1 (en) 2004-03-25
DE60033859T2 (de) 2007-11-08
EP1196410A1 (fr) 2002-04-17
HRP20010934A2 (en) 2003-06-30
US20060058309A1 (en) 2006-03-16
EE04592B1 (et) 2006-02-15
ES2215670T3 (es) 2004-10-16
TWI267513B (en) 2006-12-01
US7407969B2 (en) 2008-08-05
DK1196410T3 (da) 2004-06-28
ATE259796T1 (de) 2004-03-15
MXPA02000117A (es) 2002-07-02
PL352385A1 (en) 2003-08-25
EA004746B1 (ru) 2004-08-26
HK1045998A1 (en) 2002-12-20
ZA200110473B (en) 2003-03-20
BG106288A (en) 2002-10-31
TR200103805T2 (tr) 2002-06-21
CZ20014573A3 (cs) 2002-05-15
KR100731273B1 (ko) 2007-06-21
EP1196410B1 (fr) 2004-02-18
EA200200086A1 (ru) 2002-06-27
US7071192B1 (en) 2006-07-04
BR0011997A (pt) 2002-03-05
NO321599B1 (no) 2006-06-06
CN1358182A (zh) 2002-07-10
PT1196410E (pt) 2004-07-30
HUP0201789A2 (hu) 2002-11-28

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