EE04592B1 - Respiratoorse süntsütiaalviiruse replikatsiooni inhibiitorid, nende valmistamismeetod, kasutamine ja vaheühendid, farmatseutiline kompositsioon ja selle valmistamismeetod ning produkt - Google Patents

Respiratoorse süntsütiaalviiruse replikatsiooni inhibiitorid, nende valmistamismeetod, kasutamine ja vaheühendid, farmatseutiline kompositsioon ja selle valmistamismeetod ning produkt

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Publication number
EE04592B1
EE04592B1 EEP200100694A EEP200100694A EE04592B1 EE 04592 B1 EE04592 B1 EE 04592B1 EE P200100694 A EEP200100694 A EE P200100694A EE P200100694 A EEP200100694 A EE P200100694A EE 04592 B1 EE04592 B1 EE 04592B1
Authority
EE
Estonia
Prior art keywords
preparation
intermediates
product
pharmaceutical composition
respiratory syncytial
Prior art date
Application number
EEP200100694A
Other languages
English (en)
Estonian (et)
Inventor
Eduard Janssens Frans
Fernand Armand Lacrampe Jean
Emile Georges Guillemont J�r�me
Gaston Venet Marc
Jozef Lodewijk Marcel Andries Koenraad
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of EE200100694A publication Critical patent/EE200100694A/xx
Publication of EE04592B1 publication Critical patent/EE04592B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
EEP200100694A 1999-06-28 2000-06-20 Respiratoorse süntsütiaalviiruse replikatsiooni inhibiitorid, nende valmistamismeetod, kasutamine ja vaheühendid, farmatseutiline kompositsioon ja selle valmistamismeetod ning produkt EE04592B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99202089 1999-06-28
PCT/EP2000/005677 WO2001000615A1 (en) 1999-06-28 2000-06-20 Respiratory syncytial virus replication inhibitors

Publications (2)

Publication Number Publication Date
EE200100694A EE200100694A (et) 2003-02-17
EE04592B1 true EE04592B1 (et) 2006-02-15

Family

ID=8240374

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100694A EE04592B1 (et) 1999-06-28 2000-06-20 Respiratoorse süntsütiaalviiruse replikatsiooni inhibiitorid, nende valmistamismeetod, kasutamine ja vaheühendid, farmatseutiline kompositsioon ja selle valmistamismeetod ning produkt

Country Status (34)

Country Link
US (2) US7071192B1 (xx)
EP (2) EP1196410B1 (xx)
JP (1) JP2003503403A (xx)
KR (1) KR100731273B1 (xx)
CN (1) CN1171887C (xx)
AR (1) AR024495A1 (xx)
AT (2) ATE356121T1 (xx)
AU (1) AU774829B2 (xx)
BG (1) BG65373B1 (xx)
BR (1) BR0011997A (xx)
CA (1) CA2376785A1 (xx)
CZ (1) CZ20014573A3 (xx)
DE (2) DE60008382T2 (xx)
DK (1) DK1196410T3 (xx)
EA (1) EA004746B1 (xx)
EE (1) EE04592B1 (xx)
ES (2) ES2215670T3 (xx)
HK (1) HK1045998B (xx)
HR (2) HRP20010934A2 (xx)
HU (1) HUP0201789A3 (xx)
IL (2) IL147328A0 (xx)
MX (1) MXPA02000117A (xx)
MY (1) MY129810A (xx)
NO (1) NO321599B1 (xx)
NZ (1) NZ515392A (xx)
PL (1) PL200694B1 (xx)
PT (1) PT1196410E (xx)
SI (1) SI1196410T1 (xx)
SK (1) SK18952001A3 (xx)
TR (2) TR200500707T2 (xx)
TW (1) TWI267513B (xx)
UA (1) UA75866C2 (xx)
WO (1) WO2001000615A1 (xx)
ZA (1) ZA200110473B (xx)

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JP2006504728A (ja) 2002-10-03 2006-02-09 スミスクライン ビーチャム コーポレーション ピラソロピリジン誘導体系治療用化合物
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AR046959A1 (es) * 2003-12-18 2006-01-04 Tibotec Pharm Ltd Morfolinilo que contiene bencimidazoles como inhibidores de la replicacion del virus sincitial respiratorio
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AR046770A1 (es) * 2003-12-18 2005-12-21 Tibotec Pharm Ltd Derivados bencimidazol 5- o 6-substituidos como inhibidores de la replicacion del virus sincitial respiratorio
DE602004021135D1 (de) * 2003-12-18 2009-06-25 Tibotec Pharm Ltd Aminobenzimidazolderivate als inhibitoren der replikation des respiratory syncytial virus
RU2381224C2 (ru) 2003-12-18 2010-02-10 Тиботек Фармасьютикалз Лтд. Пиперидинаминобензимидазольные производные как ингибиторы репликации респираторного синцитиального вируса
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RU2441866C2 (ru) * 2005-06-20 2012-02-10 Тиботек Фармасьютикалз Лтд 2-замещенные бензимидазолы
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JP5487692B2 (ja) 2009-04-10 2014-05-07 国立大学法人京都大学 複素環骨格を有する化合物および該化合物を不斉触媒として用いる光学活性化合物の製造方法
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Also Published As

Publication number Publication date
HRP20010934A2 (en) 2003-06-30
EP1400519B1 (en) 2007-03-07
BR0011997A (pt) 2002-03-05
CZ20014573A3 (cs) 2002-05-15
EP1196410B1 (en) 2004-02-18
ATE259796T1 (de) 2004-03-15
EP1400519A1 (en) 2004-03-24
WO2001000615A1 (en) 2001-01-04
ZA200110473B (en) 2003-03-20
NO20016370L (no) 2001-12-27
CA2376785A1 (en) 2001-01-04
DE60033859T2 (de) 2007-11-08
UA75866C2 (en) 2006-06-15
JP2003503403A (ja) 2003-01-28
DE60008382T2 (de) 2004-12-02
HK1045998B (zh) 2005-06-03
HUP0201789A2 (hu) 2002-11-28
EA200200086A1 (ru) 2002-06-27
ES2215670T3 (es) 2004-10-16
MY129810A (en) 2007-05-31
KR100731273B1 (ko) 2007-06-21
PL200694B1 (pl) 2009-01-30
PT1196410E (pt) 2004-07-30
DK1196410T3 (da) 2004-06-28
WO2001000615A8 (en) 2002-01-10
EE200100694A (et) 2003-02-17
IL147328A0 (en) 2002-08-14
ES2283716T3 (es) 2007-11-01
IL147328A (en) 2007-06-03
HRP20080390A2 (en) 2008-12-31
PL352385A1 (en) 2003-08-25
BG65373B1 (bg) 2008-04-30
NZ515392A (en) 2004-03-26
DE60008382D1 (en) 2004-03-25
TR200500707T2 (tr) 2005-04-21
BG106288A (en) 2002-10-31
SI1196410T1 (en) 2004-08-31
HUP0201789A3 (en) 2003-12-29
DE60033859D1 (de) 2007-04-19
ATE356121T1 (de) 2007-03-15
TWI267513B (en) 2006-12-01
US7071192B1 (en) 2006-07-04
SK18952001A3 (sk) 2002-11-06
NO321599B1 (no) 2006-06-06
NO20016370D0 (no) 2001-12-27
EA004746B1 (ru) 2004-08-26
KR20020000815A (ko) 2002-01-05
AU774829B2 (en) 2004-07-08
CN1358182A (zh) 2002-07-10
AR024495A1 (es) 2002-10-02
TR200103805T2 (tr) 2002-06-21
AU5222200A (en) 2001-01-31
MXPA02000117A (es) 2002-07-02
CN1171887C (zh) 2004-10-20
US20060058309A1 (en) 2006-03-16
US7407969B2 (en) 2008-08-05
EP1196410A1 (en) 2002-04-17
HK1045998A1 (en) 2002-12-20

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