IL71248A - Chlorthalidone dispersions,their preparation and pharmaceutical compositions containing them - Google Patents

Chlorthalidone dispersions,their preparation and pharmaceutical compositions containing them

Info

Publication number: IL71248A
Authority: IL; Israel
Prior art keywords: chlorthalidone; alkanol; dispersions; preparation; pharmaceutical compositions
Prior art date: 1983-03-16

Application number

IL71248A

Other languages

English (en)

Other versions

IL71248A0 (en

Original Assignee

Boehringer Ingelheim Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-03-16

Filing date

1984-03-15

Publication date

1987-02-27

1984-03-15 Application filed by Boehringer Ingelheim Ltd filed Critical Boehringer Ingelheim Ltd

1984-06-29 Publication of IL71248A0 publication Critical patent/IL71248A0/xx

1987-02-27 Publication of IL71248A publication Critical patent/IL71248A/xx

Links

JIVPVXMEBJLZRO-CQSZACIVSA-N 2-chloro-5-[(1r)-1-hydroxy-3-oxo-2h-isoindol-1-yl]benzenesulfonamide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC([C@@]2(O)C3=CC=CC=C3C(=O)N2)=C1 JIVPVXMEBJLZRO-CQSZACIVSA-N 0.000 title abstract 4
229960001523 chlortalidone Drugs 0.000 title abstract 4
239000006185 dispersion Substances 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title 1
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
150000005215 alkyl ethers Chemical class 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
239000006227 byproduct Substances 0.000 abstract 1
230000008020 evaporation Effects 0.000 abstract 1
238000001704 evaporation Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Hematology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Compositions Of Macromolecular Compounds (AREA)
Processes Of Treating Macromolecular Substances (AREA)
Indole Compounds (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Adhesives Or Adhesive Processes (AREA)
Dental Preparations (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Physical Or Chemical Processes And Apparatus (AREA)
Cephalosporin Compounds (AREA)

IL71248A 1983-03-16 1984-03-15 Chlorthalidone dispersions,their preparation and pharmaceutical compositions containing them IL71248A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US47589883A	1983-03-16	1983-03-16

Publications (2)

Publication Number	Publication Date
IL71248A0 IL71248A0 (en)	1984-06-29
IL71248A true IL71248A (en)	1987-02-27

Family

ID=23889624

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL71248A IL71248A (en)	1983-03-16	1984-03-15	Chlorthalidone dispersions,their preparation and pharmaceutical compositions containing them

Country Status (20)

Country	Link
EP (1)	EP0125420B1 (de)
JP (1)	JPS59176212A (de)
KR (1)	KR880001755B1 (de)
AT (1)	ATE31024T1 (de)
AU (1)	AU562929B2 (de)
CA (1)	CA1212329A (de)
DD (1)	DD220225A5 (de)
DE (1)	DE3467707D1 (de)
DK (1)	DK162878C (de)
ES (1)	ES8602633A1 (de)
FI (1)	FI82188C (de)
GR (1)	GR81478B (de)
HU (1)	HU191596B (de)
IE (1)	IE57031B1 (de)
IL (1)	IL71248A (de)
NO (1)	NO164956C (de)
NZ (1)	NZ207514A (de)
PT (1)	PT78259B (de)
YU (1)	YU43349B (de)
ZA (1)	ZA841916B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4933360A (en) *	1983-03-16	1990-06-12	Boehringer Ingelheim Pharmaceuticals, Inc.	Novel chlorthalidone process and product
DE3612212A1 (de) *	1986-04-11	1987-10-15	Basf Ag	Verfahren zur herstellung von festen pharmazeutischen formen
WO1988000040A1 (en) *	1986-07-02	1988-01-14	American Health Products Corporation	Topical hair growing composition and kit
US5955475A (en) *	1997-06-30	1999-09-21	Endo Pharmaceuticals Inc.	Process for manufacturing paroxetine solid dispersions
US6264981B1 (en) *	1999-10-27	2001-07-24	Anesta Corporation	Oral transmucosal drug dosage using solid solution

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3055904A (en) *	1957-11-04	1962-09-25	Geigy Chem Corp	New isoindoline derivatives
US4128632A (en) *	1978-02-13	1978-12-05	Merck & Co., Inc.	Solubilization of Rafoxanide
US4285665A (en) *	1978-05-08	1981-08-25	Johnson, Matthey & Co., Limited	Engines

1984
- 1984-03-14 DD DD84260896A patent/DD220225A5/de not_active IP Right Cessation
- 1984-03-14 FI FI841019A patent/FI82188C/fi not_active IP Right Cessation
- 1984-03-14 YU YU458/84A patent/YU43349B/xx unknown
- 1984-03-15 CA CA000449692A patent/CA1212329A/en not_active Expired
- 1984-03-15 IL IL71248A patent/IL71248A/xx not_active IP Right Cessation
- 1984-03-15 KR KR1019840001307A patent/KR880001755B1/ko not_active Expired
- 1984-03-15 NO NO841010A patent/NO164956C/no unknown
- 1984-03-15 DE DE8484102825T patent/DE3467707D1/de not_active Expired
- 1984-03-15 DK DK156784A patent/DK162878C/da not_active IP Right Cessation
- 1984-03-15 EP EP84102825A patent/EP0125420B1/de not_active Expired
- 1984-03-15 GR GR74116A patent/GR81478B/el unknown
- 1984-03-15 PT PT78259A patent/PT78259B/pt not_active IP Right Cessation
- 1984-03-15 NZ NZ207514A patent/NZ207514A/en unknown
- 1984-03-15 IE IE647/84A patent/IE57031B1/en unknown
- 1984-03-15 ZA ZA841916A patent/ZA841916B/xx unknown
- 1984-03-15 AT AT84102825T patent/ATE31024T1/de not_active IP Right Cessation
- 1984-03-15 ES ES530628A patent/ES8602633A1/es not_active Expired
- 1984-03-15 HU HU841028A patent/HU191596B/hu not_active IP Right Cessation
- 1984-03-16 AU AU25696/84A patent/AU562929B2/en not_active Ceased
- 1984-03-16 JP JP59050836A patent/JPS59176212A/ja active Pending

Also Published As

Publication number	Publication date
ATE31024T1 (de)	1987-12-15
KR840007874A (ko)	1984-12-11
NO164956B (no)	1990-08-27
AU562929B2 (en)	1987-06-25
ES530628A0 (es)	1985-12-01
NO841010L (no)	1984-09-17
DK156784D0 (da)	1984-03-15
DD220225A5 (de)	1985-03-27
NO164956C (no)	1990-12-05
EP0125420A3 (en)	1985-03-13
HU191596B (en)	1987-03-30
PT78259A (en)	1984-04-01
IL71248A0 (en)	1984-06-29
DK162878C (da)	1992-05-18
ES8602633A1 (es)	1985-12-01
NZ207514A (en)	1987-02-20
PT78259B (en)	1986-08-08
DE3467707D1 (en)	1988-01-07
AU2569684A (en)	1984-09-20
CA1212329A (en)	1986-10-07
KR880001755B1 (ko)	1988-09-12
ZA841916B (en)	1985-11-27
FI82188C (fi)	1991-02-11
JPS59176212A (ja)	1984-10-05
DK156784A (da)	1984-09-17
FI841019A0 (fi)	1984-03-14
FI841019L (fi)	1984-09-17
YU43349B (en)	1989-06-30
DK162878B (da)	1991-12-23
HUT34343A (en)	1985-03-28
EP0125420A2 (de)	1984-11-21
YU45884A (en)	1987-06-30
IE57031B1 (en)	1992-03-25
FI82188B (fi)	1990-10-31
EP0125420B1 (de)	1987-11-25
GR81478B (de)	1984-12-11
IE840647L (en)	1984-09-16

Legal Events

Date	Code	Title	Description
1998-09-24	KB	Patent renewed
2002-12-01	MM9K	Patent not in force due to non-payment of renewal fees

Publication	Publication Date	Title
ES484167A1 (es)	1980-09-01	Un procedimiento para preparar 9-(hidroxialcohil)-purinas
IL71248A0 (en)	1984-06-29	Chlorthalidone dispersions,their preparation and pharmaceutical compositions containing them
JPS5576829A (en)	1980-06-10	Beta,gamma-dihydropolyprenyl alcohol and hypotensive agent made from it
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JPS56166172A (en)	1981-12-21	Preparation of alkylindoles
JPS5446779A (en)	1979-04-12	Preparation of 3-isoxazolylurea
JPS5512150A (en)	1980-01-28	Preparation of tartrazine
JPS54156086A (en)	1979-12-08	Preparation of hydroxypropyl cellulose
ES8303331A1 (es)	1983-02-01	Un procedimiento para preparar un pirrol-2-acetato de alquilo inferior sustituido en las posiciones 1 y 4.
JPS5527125A (en)	1980-02-27	Novel estradiol compound, its preparation and anti-tumor agent containing the same
JPS5615258A (en)	1981-02-14	Preparation of alpha-aromatic group-substituted alkanonitrile
JPS57179175A (en)	1982-11-04	Preparation of 2-benzothiazolinone derivative or salt thereof
JPS5587799A (en)	1980-07-02	1-beta-d-arabinofuranosyl-5-vinyluracil and its preparation
JPS5210291A (en)	1977-01-26	Process for preparing thienopyridine carboxylic acid derivatives
JPS56131562A (en)	1981-10-15	Preparation of oxime carbamate