IL95021A - 7-Carboxy-pyrrolo [2,1-b] thiazole-3-acetic acid derivatives, their preparation and pharmaceutical compositions containing them - Google Patents

7-Carboxy-pyrrolo [2,1-b] thiazole-3-acetic acid derivatives, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL95021A
IL95021A IL9502190A IL9502190A IL95021A IL 95021 A IL95021 A IL 95021A IL 9502190 A IL9502190 A IL 9502190A IL 9502190 A IL9502190 A IL 9502190A IL 95021 A IL95021 A IL 95021A
Authority
IL
Israel
Prior art keywords
group
methyl
thiazol
compound
ylidene
Prior art date
Application number
IL9502190A
Other languages
English (en)
Other versions
IL95021A0 (en
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Publication of IL95021A0 publication Critical patent/IL95021A0/xx
Publication of IL95021A publication Critical patent/IL95021A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Detergent Compositions (AREA)
  • Pyrrole Compounds (AREA)
IL9502190A 1989-06-13 1990-07-10 7-Carboxy-pyrrolo [2,1-b] thiazole-3-acetic acid derivatives, their preparation and pharmaceutical compositions containing them IL95021A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15114189 1989-06-13

Publications (2)

Publication Number Publication Date
IL95021A0 IL95021A0 (en) 1991-06-10
IL95021A true IL95021A (en) 1994-06-24

Family

ID=15512262

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9502190A IL95021A (en) 1989-06-13 1990-07-10 7-Carboxy-pyrrolo [2,1-b] thiazole-3-acetic acid derivatives, their preparation and pharmaceutical compositions containing them

Country Status (23)

Country Link
US (1) US5098919A (de)
EP (1) EP0410224B1 (de)
JP (1) JP2875605B2 (de)
KR (1) KR910002874A (de)
CN (1) CN1025337C (de)
AT (1) ATE132870T1 (de)
AU (1) AU624724B2 (de)
CA (1) CA2021135A1 (de)
DD (1) DD296492A5 (de)
DE (1) DE69024713T2 (de)
DK (1) DK0410224T3 (de)
ES (1) ES2084622T3 (de)
FI (1) FI903511A7 (de)
GR (1) GR3018798T3 (de)
HU (1) HU207331B (de)
IE (1) IE902545A1 (de)
IL (1) IL95021A (de)
NO (1) NO903084L (de)
NZ (1) NZ234450A (de)
PT (1) PT94688A (de)
RU (2) RU1836374C (de)
YU (1) YU136490A (de)
ZA (1) ZA905407B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0891978B1 (de) * 1997-07-18 2002-03-20 F. Hoffmann-La Roche Ag 5h-Thiazolo[3,2-a]pyrimidinderivate
US20050244892A1 (en) * 2004-02-27 2005-11-03 Lazar Mitchell A Resistin as a marker and therapeutic target for cardiovascular disease
JP5415520B2 (ja) * 2008-04-09 2014-02-12 ベー．エル．アー．ハー．エム．エス ゲゼルシャフト ミット ベシュレンクテル ハフツング 最大酸素消費量低下の予測のためのプロ−エンドセリン−１

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4193926A (en) * 1974-03-20 1980-03-18 Schering Aktiengesellschaft 4-(Polyalkoxy phenyl)-2-pyrrolidones
US4347186A (en) * 1980-10-20 1982-08-31 Syntex (U.S.A.) Inc. Process for preparing 5-aroyl 1,2-dihydro-3-H pyrrolo[1,2-a]pyrrole-1-carboxylic acids and novel intermediates therein

Also Published As

Publication number Publication date
JP2875605B2 (ja) 1999-03-31
RU1836374C (ru) 1993-08-23
KR910002874A (ko) 1991-02-26
HUT57221A (en) 1991-11-28
NO903084L (no) 1991-01-14
HU904214D0 (en) 1990-12-28
NZ234450A (en) 1991-10-25
FI903511A0 (fi) 1990-07-11
ES2084622T3 (es) 1996-05-16
US5098919A (en) 1992-03-24
EP0410224A1 (de) 1991-01-30
CN1049350A (zh) 1991-02-20
CA2021135A1 (en) 1991-01-14
DE69024713D1 (de) 1996-02-22
PT94688A (pt) 1991-03-20
NO903084D0 (no) 1990-07-11
FI903511A7 (fi) 1991-01-14
RU2026288C1 (ru) 1995-01-09
AU5890490A (en) 1991-01-17
DE69024713T2 (de) 1996-06-13
HU207331B (en) 1993-03-29
AU624724B2 (en) 1992-06-18
DD296492A5 (de) 1991-12-05
GR3018798T3 (en) 1996-04-30
JPH03128385A (ja) 1991-05-31
IE902545A1 (en) 1991-02-27
IL95021A0 (en) 1991-06-10
DK0410224T3 (da) 1996-02-05
ATE132870T1 (de) 1996-01-15
CN1025337C (zh) 1994-07-06
ZA905407B (en) 1991-04-24
EP0410224B1 (de) 1996-01-10
YU136490A (sh) 1992-09-07

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