IL97804A - Oligonucleotide analogs in which one or more of th e inter nucleotide phosphodiester linkages have been replaced by a sulfer based likage, their preparation and antisense, triplex and antiviral reagents containing them - Google Patents

Oligonucleotide analogs in which one or more of th e inter nucleotide phosphodiester linkages have been replaced by a sulfer based likage, their preparation and antisense, triplex and antiviral reagents containing them

Info

Publication number
IL97804A
IL97804A IL9780491A IL9780491A IL97804A IL 97804 A IL97804 A IL 97804A IL 9780491 A IL9780491 A IL 9780491A IL 9780491 A IL9780491 A IL 9780491A IL 97804 A IL97804 A IL 97804A
Authority
IL
Israel
Prior art keywords
compound
alkyl
carbon atoms
sulfamate
linkage
Prior art date
Application number
IL9780491A
Other languages
English (en)
Other versions
IL97804A0 (en
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of IL97804A0 publication Critical patent/IL97804A0/xx
Publication of IL97804A publication Critical patent/IL97804A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL9780491A 1990-04-10 1991-04-09 Oligonucleotide analogs in which one or more of th e inter nucleotide phosphodiester linkages have been replaced by a sulfer based likage, their preparation and antisense, triplex and antiviral reagents containing them IL97804A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/507,693 US5470967A (en) 1990-04-10 1990-04-10 Oligonucleotide analogs with sulfamate linkages

Publications (2)

Publication Number Publication Date
IL97804A0 IL97804A0 (en) 1992-06-21
IL97804A true IL97804A (en) 1995-07-31

Family

ID=24019741

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9780491A IL97804A (en) 1990-04-10 1991-04-09 Oligonucleotide analogs in which one or more of th e inter nucleotide phosphodiester linkages have been replaced by a sulfer based likage, their preparation and antisense, triplex and antiviral reagents containing them

Country Status (16)

Country Link
US (1) US5470967A (de)
EP (1) EP0517796B1 (de)
JP (1) JP3050595B2 (de)
AT (1) ATE121416T1 (de)
AU (1) AU639770B2 (de)
CA (1) CA2079777C (de)
DE (1) DE69109100T2 (de)
DK (1) DK0517796T3 (de)
ES (1) ES2071989T3 (de)
HK (1) HK109495A (de)
IE (1) IE73244B1 (de)
IL (1) IL97804A (de)
MY (1) MY107440A (de)
NZ (1) NZ237723A (de)
WO (1) WO1991015500A1 (de)
ZA (1) ZA912660B (de)

Families Citing this family (968)

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JPH05506014A (ja) 1993-09-02
IL97804A0 (en) 1992-06-21
MY107440A (en) 1995-12-30
US5470967A (en) 1995-11-28
IE73244B1 (en) 1997-05-21
IE911176A1 (en) 1991-10-23
JP3050595B2 (ja) 2000-06-12
AU639770B2 (en) 1993-08-05
DK0517796T3 (da) 1995-07-03
EP0517796A1 (de) 1992-12-16
NZ237723A (en) 1992-04-28
WO1991015500A1 (en) 1991-10-17
ZA912660B (en) 1991-12-24
EP0517796B1 (de) 1995-04-19
ATE121416T1 (de) 1995-05-15
DE69109100D1 (de) 1995-05-24
CA2079777C (en) 2002-07-30
CA2079777A1 (en) 1991-10-11
AU7458191A (en) 1991-10-30
DE69109100T2 (de) 1995-08-31
HK109495A (en) 1995-07-14
ES2071989T3 (es) 1995-07-01

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