IN170979B - - Google Patents

Info

Publication number: IN170979B
Authority: IN; India
Prior art keywords: alkyl; ethynyl; fluorophenyl; bis; opt
Prior art date: 1989-08-10

Application number

IN687/CAL/90A

Other languages

English (en)

Inventor

Edit Toth

Jozsef Torley

Dr Sandor Gorog

Dr Laszlo Szporny

Bela Kiss

Dr Eva Palosi

Dr Dora Groo

Dr Istvan Laszlovszky

Dr Erzsebet Lapis

Ferenc Auth

Dr Laszlo Gall

Original Assignee

Richter Gedeon Vegyeszet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-08-10

Filing date

1990-08-09

Publication date

1992-06-27

1990-08-09 Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet

1991-07-22 Priority to IN550/CAL/93A priority Critical patent/IN172010B/en

1992-06-27 Publication of IN170979B publication Critical patent/IN170979B/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Hydrogenated Pyridines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

IN687/CAL/90A 1989-08-10 1990-08-09 IN170979B (es)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
IN550/CAL/93A IN172010B (es)	1989-08-10	1991-07-22

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU894094A HU204276B (en)	1989-08-10	1989-08-10	Process for producing new 1-oxa-2-oxo-4-methylen-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them

Publications (1)

Publication Number	Publication Date
IN170979B true IN170979B (es)	1992-06-27

Family

ID=10966866

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IN687/CAL/90A IN170979B (es)	1989-08-10	1990-08-09

Country Status (26)

Country	Link
US (2)	US5132303A (es)
EP (2)	EP0412821B1 (es)
JP (2)	JPH0383985A (es)
KR (2)	KR940002826B1 (es)
CN (1)	CN1025031C (es)
AT (2)	ATE104671T1 (es)
AU (2)	AU621771B2 (es)
CA (2)	CA2023018C (es)
DD (2)	DD299431A5 (es)
DE (2)	DE69014008T2 (es)
DK (1)	DK0413516T3 (es)
ES (2)	ES2063923T3 (es)
FI (1)	FI93456C (es)
HK (1)	HK118295A (es)
HU (2)	HU206677B (es)
IE (1)	IE902885A1 (es)
IL (2)	IL95324A (es)
IN (1)	IN170979B (es)
IS (1)	IS3612A7 (es)
MY (1)	MY107240A (es)
NO (1)	NO903511L (es)
NZ (2)	NZ234846A (es)
PL (2)	PL164662B1 (es)
SG (1)	SG59864G (es)
YU (2)	YU150489A (es)
ZA (3)	ZA906304B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3751404T2 (de) *	1986-12-17	1995-12-21	Glaxo Group Ltd	Verwendung von heterocyclischen Verbindungen zur Behandlung von Bewusstseinsstörungen.
YU150489A (sh) *	1989-08-10	1992-12-21	W.L. Gore & Co. Gmbh.	Uređaj za ispitivanje odevnih predmeta na nepromočivost
HU204529B (en) *	1989-08-10	1992-01-28	Richter Gedeon Vegyeszet	Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them
US5852029A (en) *	1990-04-10	1998-12-22	Israel Institute For Biological Research	Aza spiro compounds acting on the cholinergic system with muscarinic agonist activity
US5534520A (en) *	1990-04-10	1996-07-09	Fisher; Abraham	Spiro compounds containing five-membered rings
EP0492020A1 (en) *	1990-12-21	1992-07-01	Merrell Dow Pharmaceuticals Inc.	Use of certain esters of hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3(4H)-one and related compounds for treating cognitive disorders
GB9206989D0 (en) *	1992-03-31	1992-05-13	Glaxo Group Ltd	Chemical compounds
US5756743A (en)	1996-04-10	1998-05-26	Hoechst Marion Roussel Inc.	Spiro cyclopent b!indole-piperidines!
US6100256A (en) *	1996-12-02	2000-08-08	Merck Sharp & Dohme Ltd.	Use of NK-1 receptors antagonists for treating schizophrenic disorders
US6974825B1 (en)	1996-12-20	2005-12-13	Astrazeneca Canada Inc.	Compounds with analgesic effect
SE9604786D0 (sv)	1996-12-20	1996-12-20	Astra Pharma Inc	New compounds
SE9904675D0 (sv)	1999-12-20	1999-12-20	Astra Pharma Inc	Novel compounds
SE0101771D0 (sv)	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101770D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101773D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101769D0 (sv)	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
KR20030087248A (ko) *	2002-05-08	2003-11-14	(주)씨엔아이	온라인을 통한 상거래 기초항목의 설정기능을 갖는 상거래관리장치
CN102459278A (zh) *	2009-06-16	2012-05-16	默沙东公司	取代的-1,3,8-三氮杂螺[4.5]癸烷-2,4-二酮
GB201416352D0 (en) *	2014-09-16	2014-10-29	Shire Internat Gmbh	Spirocyclic derivatives
GB201416346D0 (en) *	2014-09-16	2014-10-29	Shire Internat Gmbh	Spirocyclic derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL127065C (es) *	1964-04-22
CH601304A5 (es) *	1974-02-12	1978-07-14	Buskine Sa
BE790675A (fr) *	1971-10-29	1973-04-27	Science Union & Cie	Nouveaux derives de l'oxa-1 diaza-3,8 spiro (4,5) decane
FR2615515B1 (fr) *	1987-05-22	1989-06-30	Adir	Nouveaux derives du spiro 4, 5 decane, leur procede de preparation et les compositions pharmaceutiques les renfermant
HU204530B (en) *	1989-08-10	1992-01-28	Richter Gedeon Vegyeszet	Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them
HU204529B (en) *	1989-08-10	1992-01-28	Richter Gedeon Vegyeszet	Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them
YU150489A (sh) *	1989-08-10	1992-12-21	W.L. Gore & Co. Gmbh.	Uređaj za ispitivanje odevnih predmeta na nepromočivost

1989
- 1989-07-27 YU YU150489A patent/YU150489A/sh unknown
- 1989-08-10 HU HU903233A patent/HU206677B/hu not_active IP Right Cessation
- 1989-08-10 HU HU894094A patent/HU204276B/hu not_active IP Right Cessation
1990
- 1990-08-08 KR KR1019900012168A patent/KR940002826B1/ko not_active Expired - Fee Related
- 1990-08-08 KR KR1019900012169A patent/KR940000830B1/ko not_active Expired - Fee Related
- 1990-08-09 CA CA002023018A patent/CA2023018C/en not_active Expired - Fee Related
- 1990-08-09 IE IE288590A patent/IE902885A1/en unknown
- 1990-08-09 JP JP2209363A patent/JPH0383985A/ja active Pending
- 1990-08-09 EP EP90308779A patent/EP0412821B1/en not_active Expired - Lifetime
- 1990-08-09 DD DD90343359A patent/DD299431A5/de not_active IP Right Cessation
- 1990-08-09 YU YU154090A patent/YU154090A/sh unknown
- 1990-08-09 DK DK90308783.1T patent/DK0413516T3/da active
- 1990-08-09 NZ NZ234846A patent/NZ234846A/en unknown
- 1990-08-09 ZA ZA906304A patent/ZA906304B/xx unknown
- 1990-08-09 DE DE69014008T patent/DE69014008T2/de not_active Expired - Fee Related
- 1990-08-09 IL IL9532490A patent/IL95324A/en not_active IP Right Cessation
- 1990-08-09 IL IL9532590A patent/IL95325A/en not_active IP Right Cessation
- 1990-08-09 AU AU60803/90A patent/AU621771B2/en not_active Ceased
- 1990-08-09 CA CA002023015A patent/CA2023015A1/en not_active Abandoned
- 1990-08-09 ES ES90308779T patent/ES2063923T3/es not_active Expired - Lifetime
- 1990-08-09 EP EP90308783A patent/EP0413516B1/en not_active Expired - Lifetime
- 1990-08-09 ZA ZA906300A patent/ZA906300B/xx unknown
- 1990-08-09 NZ NZ234843A patent/NZ234843A/en unknown
- 1990-08-09 ES ES90308783T patent/ES2052179T3/es not_active Expired - Lifetime
- 1990-08-09 NO NO90903511A patent/NO903511L/no unknown
- 1990-08-09 SG SG1995903969A patent/SG59864G/en unknown
- 1990-08-09 DE DE69008275T patent/DE69008275T2/de not_active Expired - Fee Related
- 1990-08-09 IS IS3612A patent/IS3612A7/is unknown
- 1990-08-09 AT AT9090308783T patent/ATE104671T1/de not_active IP Right Cessation
- 1990-08-09 AU AU60804/90A patent/AU621238B2/en not_active Ceased
- 1990-08-09 AT AT90308779T patent/ATE113951T1/de not_active IP Right Cessation
- 1990-08-09 IN IN687/CAL/90A patent/IN170979B/en unknown
- 1990-08-09 DD DD90343354A patent/DD299428A5/de not_active IP Right Cessation
- 1990-08-09 JP JP2209362A patent/JPH0381277A/ja active Pending
- 1990-08-09 ZA ZA906299A patent/ZA906299B/xx unknown
- 1990-08-10 FI FI903974A patent/FI93456C/fi not_active IP Right Cessation
- 1990-08-10 US US07/566,278 patent/US5132303A/en not_active Expired - Fee Related
- 1990-08-10 US US07/566,279 patent/US5132309A/en not_active Expired - Fee Related
- 1990-08-10 CN CN90106974A patent/CN1025031C/zh not_active Expired - Fee Related
- 1990-08-10 MY MYPI90001343A patent/MY107240A/en unknown
- 1990-08-10 PL PL90291648A patent/PL164662B1/pl unknown
- 1990-08-10 PL PL90286443A patent/PL163899B1/pl unknown
1995
- 1995-07-20 HK HK118295A patent/HK118295A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR940002826B1 (ko)	1994-04-04
DD299431A5 (de)	1992-04-16
DK0413516T3 (da)	1994-05-24
CA2023015A1 (en)	1991-02-11
EP0412821B1 (en)	1994-11-09
HUT55785A (en)	1991-06-28
ES2063923T3 (es)	1995-01-16
EP0412821A2 (en)	1991-02-13
HU903233D0 (en)	1990-10-28
JPH0383985A (ja)	1991-04-09
HU204276B (en)	1991-12-30
HK118295A (en)	1995-07-28
HUT59375A (en)	1992-05-28
DE69008275T2 (de)	1994-08-04
ATE104671T1 (de)	1994-05-15
AU6080390A (en)	1991-02-14
ZA906304B (en)	1991-06-26
CA2023018A1 (en)	1991-02-11
YU154090A (sh)	1992-12-21
CA2023018C (en)	1995-11-28
IL95325A (en)	1994-06-24
PL163899B1 (pl)	1994-05-31
MY107240A (en)	1995-10-31
SG59864G (en)	1995-09-01
NO903511L (no)	1991-02-11
IE902885A1 (en)	1991-02-27
KR910004631A (ko)	1991-03-29
JPH0381277A (ja)	1991-04-05
FI903974A0 (fi)	1990-08-10
ES2052179T3 (es)	1994-07-01
YU150489A (sh)	1992-12-21
IL95324A (en)	1994-02-27
ATE113951T1 (de)	1994-11-15
ZA906300B (en)	1991-05-29
DE69014008T2 (de)	1995-03-23
EP0413516A2 (en)	1991-02-20
ZA906299B (en)	1991-06-26
EP0413516B1 (en)	1994-04-20
FI93456B (fi)	1994-12-30
EP0412821A3 (en)	1991-11-27
US5132303A (en)	1992-07-21
AU621771B2 (en)	1992-03-19
NZ234846A (en)	1992-03-26
KR910004630A (ko)	1991-03-29
EP0413516A3 (en)	1991-11-27
DD299428A5 (de)	1992-04-16
HU206677B (en)	1992-12-28
IL95324A0 (en)	1991-06-30
PL286443A1 (en)	1992-01-13
DE69008275D1 (de)	1994-05-26
US5132309A (en)	1992-07-21
PL291648A1 (en)	1992-06-01
NO903511D0 (no)	1990-08-09
FI93456C (fi)	1995-04-10
AU6080490A (en)	1991-02-14
NZ234843A (en)	1992-03-26
AU621238B2 (en)	1992-03-05
DE69014008D1 (de)	1994-12-15
IL95325A0 (en)	1991-06-30
KR940000830B1 (ko)	1994-02-02
PL164662B1 (pl)	1994-09-30
CN1049349A (zh)	1991-02-20
CN1025031C (zh)	1994-06-15
IS3612A7 (is)	1991-02-11

Publication	Publication Date	Title
IN170979B (es)	1992-06-27
GR3029408T3 (en)	1999-05-28	Novel piperidine derivatives, useful as neurokinin receptor antagonists
DE3870338D1 (de)	1992-05-27	Dhp-manteltablette.
PT737678E (pt)	2002-11-29	Derivados 4-indolilpiperazinilo
DE3889497D1 (de)	1994-06-16	3,4-Dihydro-2-alkyl-3-oxo-N-aryl-2H-[1]benzothieno[3,2-e]-1,2-thiazine-4-carboxamid-1,1-dioxide.
ITMI920843A1 (it)	1993-10-07	Scambio per una rotaia cava di profilato
DE3867705D1 (de)	1992-02-27	2-anilino-chinoline, verfahren zu ihrer herstellung und diese enthaltende fungizide.
FI921846A7 (fi)	1992-10-27	Indolinihydrokloridisuoloja ja menetelmä niiden valmistamiseksi
FI941696A7 (fi)	1994-04-13	Systeemi lääkkeen oraaliseen antoon
ITBZ920005A0 (it)	1992-01-22	Dispositivo di accumulo per cartucce di posta pneumatica