EE03223B1 - Kiiretoimelist dihüdropüridiinühendit sisaldav farmatseutiline emulsioon vererõhu alandamiseks ja selle valmistamise protsess - Google Patents

Kiiretoimelist dihüdropüridiinühendit sisaldav farmatseutiline emulsioon vererõhu alandamiseks ja selle valmistamise protsess

Info

Publication number
EE03223B1
EE03223B1 EE9600052A EE9600052A EE03223B1 EE 03223 B1 EE03223 B1 EE 03223B1 EE 9600052 A EE9600052 A EE 9600052A EE 9600052 A EE9600052 A EE 9600052A EE 03223 B1 EE03223 B1 EE 03223B1
Authority
EE
Estonia
Prior art keywords
preparation
blood pressure
emulsion containing
pharmaceutical emulsion
dihydropyridine compound
Prior art date
Application number
EE9600052A
Other languages
English (en)
Estonian (et)
Inventor
Hjalmar Andersson Kjell
Kristina Byr�d Eva
Hansson Anna-Carin
Nordlander Margareta
Christer Westerlund Rolf
Original Assignee
Astra Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Aktiebolag filed Critical Astra Aktiebolag
Publication of EE03223B1 publication Critical patent/EE03223B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
EE9600052A 1993-11-12 1994-11-03 Kiiretoimelist dihüdropüridiinühendit sisaldav farmatseutiline emulsioon vererõhu alandamiseks ja selle valmistamise protsess EE03223B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9303744A SE9303744D0 (sv) 1993-11-12 1993-11-12 Pharmaceutical emulsion
PCT/SE1994/001032 WO1995013066A1 (en) 1993-11-12 1994-11-03 Pharmaceutical emulsion

Publications (1)

Publication Number Publication Date
EE03223B1 true EE03223B1 (et) 1999-10-15

Family

ID=20391731

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9600052A EE03223B1 (et) 1993-11-12 1994-11-03 Kiiretoimelist dihüdropüridiinühendit sisaldav farmatseutiline emulsioon vererõhu alandamiseks ja selle valmistamise protsess

Country Status (30)

Country Link
US (1) US5739152A (is)
EP (1) EP0727997B1 (is)
JP (1) JP3759951B2 (is)
KR (1) KR100345627B1 (is)
CN (1) CN1072934C (is)
AT (1) ATE213158T1 (is)
AU (1) AU678650B2 (is)
CA (1) CA2176360C (is)
CZ (1) CZ290772B6 (is)
DE (1) DE69429871T2 (is)
DK (1) DK0727997T3 (is)
EE (1) EE03223B1 (is)
EG (1) EG20764A (is)
ES (1) ES2172572T3 (is)
FI (1) FI116999B (is)
HU (1) HU223142B1 (is)
IL (1) IL111345A (is)
IS (1) IS2036B (is)
MY (1) MY121201A (is)
NO (1) NO314877B1 (is)
NZ (1) NZ276197A (is)
PL (1) PL181462B1 (is)
PT (1) PT727997E (is)
RU (1) RU2144358C1 (is)
SA (1) SA94150314B1 (is)
SE (1) SE9303744D0 (is)
SK (1) SK283271B6 (is)
UA (1) UA40633C2 (is)
WO (1) WO1995013066A1 (is)
ZA (1) ZA948180B (is)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030158220A1 (en) * 1997-11-03 2003-08-21 Foss Joseph F. Use of methylnaltrexone and related compounds to treat chronic opioid use side effects
HK1039458B (zh) * 1998-05-29 2006-09-01 Skyepharma Canada Inc. 熱保護微粒組合物及其最終蒸汽滅菌的方法
SE9804002D0 (sv) * 1998-11-23 1998-11-23 Astra Ab New manufacturing process
DE10036871A1 (de) 2000-07-28 2002-02-14 Pharmasol Gmbh Dispersionen zur Formulierung wenig oder schwer löslicher Wirkstoffe
CA2449856C (en) 2001-06-15 2009-03-10 Cornerstone Pharmaceuticals Pharmaceutical and diagnostic compositions containing nanoparticles useful for treating targeted tissues and cells
HRP20150037T4 (hr) 2003-04-08 2022-09-02 Progenics Pharmaceuticals, Inc. Farmaceutske formulacije koje sadrže metilnaltrekson
AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
AR057035A1 (es) 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
TWI489984B (zh) 2006-08-04 2015-07-01 Wyeth Corp 用於非經腸道傳輸化合物之配方及其用途
TW200817048A (en) * 2006-09-08 2008-04-16 Wyeth Corp Dry powder compound formulations and uses thereof
SI2565195T1 (sl) 2007-03-29 2015-09-30 Wyeth Llc Periferalni opioidni receptorji in antagonisti in njih uporaba
CL2008000905A1 (es) * 2007-03-29 2008-08-22 Progenics Pharm Inc Compuestos derivados de morfina, antagonistas del receptor opioide periferico; metodo de preparacion; composicion farmaceutica; y uso para reducir los efectos de la actividad opioide endogena.
MX2009010550A (es) * 2007-03-29 2009-12-14 Progenics Pharm Inc Formas de cristal de bromuro de (r)-n-metilnaltrexona y uso de las mismas.
EP2240489A1 (en) * 2008-02-06 2010-10-20 Progenics Pharmaceuticals, Inc. Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone
US20100105743A1 (en) * 2008-08-01 2010-04-29 Gopal Krishna Pharmaceutical compositions and methods for stabilizing the same
PL2320740T3 (pl) 2008-08-01 2014-09-30 The Medicines Co Kompozycje farmaceutyczne klewidypiny oraz sposoby ich wytwarzania z niskim stężeniem zanieczyszczeń
CA2676881C (en) * 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof
US9034389B2 (en) 2009-03-11 2015-05-19 Stable Solutions Llc Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
US8993625B2 (en) 2009-03-11 2015-03-31 Stable Solutions Llc Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle
WO2010107081A1 (ja) * 2009-03-19 2010-09-23 第一三共株式会社 包装により安定保存された固形製剤
CN101780036B (zh) * 2010-03-30 2011-11-16 武汉武药科技有限公司 丁酸氯维地平脂微球注射液及其制备方法
EP2627173B2 (en) * 2010-10-12 2018-07-04 Chiesi Farmaceutici S.p.A. Clevidipine emulsion formulations containing antimicrobial agents
US8658676B2 (en) * 2010-10-12 2014-02-25 The Medicines Company Clevidipine emulsion formulations containing antimicrobial agents
CN102531998A (zh) * 2010-12-09 2012-07-04 天津药物研究院 α型多晶型丁酸氯维地平结晶、其制备方法、用途和药物组合物
CN102525918A (zh) * 2010-12-30 2012-07-04 天津药物研究院 一种丁酸氯维地平的脂肪乳注射液及其制备工艺
US20120213855A1 (en) * 2011-02-17 2012-08-23 Cima Labs Inc. Dosage forms for weakly ionizable compounds
CA2832066C (en) * 2011-04-01 2023-04-18 The Medicines Company Short-acting dihydropyridines (clevidipine) for use in reducing stroke damage
CN110075310A (zh) 2011-12-20 2019-08-02 维奥姆治疗有限公司 用于治疗真菌感染的局部油组合物
UA117571C2 (uk) 2012-10-26 2018-08-27 Чіесі Фармацеутічі С.П.А. Способи контролювання кров'яного тиску та зниження диспное при серцевій недостатності
CN103110580B (zh) * 2013-02-20 2014-09-17 北京德立福瑞医药科技有限公司 丁酸氯维地平注射剂
WO2014167554A2 (en) * 2013-04-12 2014-10-16 Vyome Biosciences Pvt. Ltd. Composition and formulation of antimicrobial agents, processes thereof and methods for treating microbial infections
WO2015179334A1 (en) 2014-05-19 2015-11-26 The Medicines Company Clevidipine nanoparticles and pharmaceutical compositions thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3315805A1 (de) * 1983-04-30 1984-11-08 Bayer Ag, 5090 Leverkusen Wirkstoffzubereitungen
DE3339236A1 (de) * 1983-10-28 1985-05-09 Bayer Ag Arzneimittelzubereitung
DE3515335C2 (de) * 1985-04-27 1995-01-26 Bayer Ag Arzneizubereitung enthaltend Dihydropyridine und Verfahren zu ihrer Herstellung
DE4217842A1 (de) * 1992-05-29 1993-12-02 Dietl Hans Calciumantagonisten enthaltende pharmazeutische Zubereitung zur intravenösen und intrakoronaren Applikation sowie Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
NO961898L (no) 1996-06-25
EG20764A (en) 2000-01-31
AU678650B2 (en) 1997-06-05
DE69429871D1 (de) 2002-03-21
PL314263A1 (en) 1996-09-02
KR100345627B1 (ko) 2003-03-15
SK283271B6 (sk) 2003-04-01
JPH09505045A (ja) 1997-05-20
EP0727997B1 (en) 2002-02-13
FI961999L (fi) 1996-05-10
CZ133896A3 (en) 1996-09-11
IL111345A0 (en) 1994-12-29
JP3759951B2 (ja) 2006-03-29
US5739152A (en) 1998-04-14
AU1037195A (en) 1995-05-29
CA2176360C (en) 2005-08-23
PL181462B1 (pl) 2001-07-31
FI961999A0 (fi) 1996-05-10
CZ290772B6 (cs) 2002-10-16
SE9303744D0 (sv) 1993-11-12
HK1013261A1 (en) 1999-08-20
ZA948180B (en) 1995-05-12
ATE213158T1 (de) 2002-02-15
CN1072934C (zh) 2001-10-17
IS2036B (is) 2005-08-15
SA94150314B1 (ar) 2005-06-14
SK59796A3 (en) 1996-12-04
HU223142B1 (hu) 2004-03-29
PT727997E (pt) 2002-07-31
CA2176360A1 (en) 1995-05-18
WO1995013066A1 (en) 1995-05-18
FI116999B (fi) 2006-05-15
RU2144358C1 (ru) 2000-01-20
MY121201A (en) 2006-01-28
DK0727997T3 (da) 2002-04-22
IS4224A (is) 1995-05-13
DE69429871T2 (de) 2002-08-22
UA40633C2 (uk) 2001-08-15
CN1136774A (zh) 1996-11-27
HUT74474A (en) 1996-12-30
IL111345A (en) 2000-08-31
NZ276197A (en) 1997-04-24
EP0727997A1 (en) 1996-08-28
HU9601268D0 (en) 1996-07-29
NO314877B1 (no) 2003-06-10
ES2172572T3 (es) 2002-10-01
NO961898D0 (no) 1996-05-10

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