IS6874A - 3,7-díasabísýkló[3.3.0]oktön og notkun þeirra í meðhöndlun á hjartsláttarglöpum - Google Patents

3,7-díasabísýkló[3.3.0]oktön og notkun þeirra í meðhöndlun á hjartsláttarglöpum

Info

Publication number
IS6874A
IS6874A IS6874A IS6874A IS6874A IS 6874 A IS6874 A IS 6874A IS 6874 A IS6874 A IS 6874A IS 6874 A IS6874 A IS 6874A IS 6874 A IS6874 A IS 6874A
Authority
IS
Iceland
Prior art keywords
arrhythmias
diazabicyclo
octane
treatment
Prior art date
Application number
IS6874A
Other languages
English (en)
Inventor
Björsne Magnus
Pontén Fritiof
Strandlund Gert
Svensson Peder
Wilstermann Michael
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of IS6874A publication Critical patent/IS6874A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IS6874A 2001-02-02 2003-07-11 3,7-díasabísýkló[3.3.0]oktön og notkun þeirra í meðhöndlun á hjartsláttarglöpum IS6874A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0100326A SE0100326D0 (sv) 2001-02-02 2001-02-02 New compounds
PCT/SE2002/000152 WO2002060902A1 (en) 2001-02-02 2002-01-29 3,7-diazabicyclo[3.3.0]octanes and their use in the treatment of cardiac arrhythmias

Publications (1)

Publication Number Publication Date
IS6874A true IS6874A (is) 2004-07-11

Family

ID=20282824

Family Applications (1)

Application Number Title Priority Date Filing Date
IS6874A IS6874A (is) 2001-02-02 2003-07-11 3,7-díasabísýkló[3.3.0]oktön og notkun þeirra í meðhöndlun á hjartsláttarglöpum

Country Status (29)

Country Link
US (1) US7144914B2 (is)
EP (1) EP1360187B1 (is)
JP (1) JP2004522749A (is)
KR (1) KR20030074764A (is)
CN (2) CN1263758C (is)
AR (1) AR035423A1 (is)
AT (1) ATE298339T1 (is)
BG (1) BG108035A (is)
BR (1) BR0206791A (is)
CA (1) CA2434970A1 (is)
CZ (1) CZ20032061A3 (is)
DE (1) DE60204755T2 (is)
EE (1) EE200300364A (is)
ES (1) ES2243706T3 (is)
HU (1) HUP0302538A3 (is)
IL (1) IL156734A0 (is)
IS (1) IS6874A (is)
MX (1) MXPA03006579A (is)
MY (1) MY136788A (is)
NO (1) NO20033434L (is)
NZ (1) NZ526992A (is)
PL (1) PL363454A1 (is)
PT (1) PT1360187E (is)
RU (1) RU2293085C2 (is)
SE (1) SE0100326D0 (is)
SK (1) SK9702003A3 (is)
UA (1) UA75382C2 (is)
WO (1) WO2002060902A1 (is)
ZA (1) ZA200305345B (is)

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CA2440803A1 (en) * 2001-03-07 2002-09-12 Pfizer Products Inc. Modulators of chemokine receptor activity
PT1761542E (pt) * 2004-06-09 2008-03-26 Hoffmann La Roche Derivados de octa-hidro-pirrolo[3,4-c) pirrole e o seu uso com agentes antivirais
US7665658B2 (en) 2005-06-07 2010-02-23 First Data Corporation Dynamic aggregation of payment transactions
GB0514018D0 (en) * 2005-07-07 2005-08-17 Ionix Pharmaceuticals Ltd Chemical compounds
MX2012004753A (es) 2009-10-23 2012-09-07 Janssen Pharmaceutica Nv Octahidropirrolo[3,4-c]pirrolos disustituidos como moduladores del receptor de orexina.
CN102718695B (zh) * 2012-06-25 2014-04-02 华东师范大学 一种氮杂双环[3.3.0]辛烷衍生物的合成方法
CN112500338A (zh) 2013-03-15 2021-03-16 全球血液疗法股份有限公司 化合物及其用于调节血红蛋白的用途
JP6647592B2 (ja) * 2013-07-03 2020-02-14 ルンドベック ラ ホーヤ リサーチ センター，インク． ピロロピロールカルバメート、および関連する有機化合物、医薬組成物、ならびにその医学的使用
EA202092627A1 (ru) 2013-11-18 2021-09-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
RS63296B1 (sr) 2016-03-10 2022-07-29 Janssen Pharmaceutica Nv Metode lečenja depresije korišćenjem antagonista receptora oreksin-2
US10851053B2 (en) 2016-06-08 2020-12-01 Glaxosmithkline Intellectual Property Development Limited Chemical compounds
PT3448859T (pt) 2017-03-20 2019-10-25 Forma Therapeutics Inc Composições de pirrolopirrole como ativadores de piruvato quinase (pkr).
US12053458B2 (en) 2018-09-19 2024-08-06 Novo Nordisk Health Care Ag Treating sickle cell disease with a pyruvate kinase R activating compound
ES2989438T3 (es) 2018-09-19 2024-11-26 Novo Nordisk Healthcare Ag Activación de la piruvato cinasa R
CN114615977B (zh) 2019-09-19 2025-01-14 诺沃挪第克健康护理股份公司 丙酮酸激酶r(pkr)活化组合物
RU2726120C1 (ru) * 2019-09-24 2020-07-09 Федеральное государственное бюджетное научное учреждение Уфимский федеральный исследовательский центр Российской академии наук N-алкил-n-{ [3-алкил-3,8-диазабицикло[3.2.1]окта-1(7),5-диен-8-ил]метил} амины, обладающие цитотоксической активностью в отношении клеточной линии нек 293
US12128035B2 (en) 2021-03-19 2024-10-29 Novo Nordisk Health Care Ag Activating pyruvate kinase R

Family Cites Families (26)

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Publication number Priority date Publication date Assignee Title
SU482990A1 (ru) * 1973-09-03 1978-04-15 Предприятие П/Я Г-4059 Способ получени 1,4-диазабицикло(2,2,2)-октана
DE2428792A1 (de) 1974-06-14 1976-01-02 Knoll Ag Neue antiarrhythmika
DE3112055A1 (de) 1981-03-27 1982-10-07 Basf Ag, 6700 Ludwigshafen Bispidinderivate, ihre herstellung und diese enthaltende arzneimittel
DE3234697A1 (de) 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
PT88381B (pt) 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos
DE3732094A1 (de) 1987-09-24 1989-04-06 Basf Ag Bispidinderivate als klasse iii-antiarrhythmika
DE3930266A1 (de) * 1989-09-11 1991-03-14 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US5110933A (en) 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
US5468858A (en) 1993-10-28 1995-11-21 The Board Of Regents Of Oklahoma State University Physical Sciences N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents
DE4338396A1 (de) 1993-11-10 1995-05-11 Basf Ag N-Substituierte Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
DE4341403A1 (de) 1993-12-04 1995-06-08 Basf Ag N-substituierte 3-Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
DE4402931A1 (de) 1994-02-01 1995-08-03 Kali Chemie Pharma Gmbh Neue 3-Phenylsulfonyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel
US5457121A (en) 1994-09-02 1995-10-10 Eli Lilly And Company Cis-hexahydro-5-(1,2,3,4-tetrahydro-2-naphthalenyl)pyrrolo<3,4-c>pyrroles as inhibitors of serotonin reuptake
ES2207657T3 (es) * 1995-02-27 2004-06-01 F. Hoffmann-La Roche Ag Pirrolderivados de dioxopirrolo.
ES2162047T3 (es) 1995-05-11 2001-12-16 Upjohn Co Oxazolidinonas con resto diazinilo y carbazinilo espirociclico y biciclico.
WO1996039407A1 (en) * 1995-06-06 1996-12-12 Abbott Laboratories Quinolizinone type compounds
EP1019385B1 (en) 1995-09-15 2004-01-14 PHARMACIA &amp; UPJOHN COMPANY Aminoaryl oxazolidinone n-oxides
GB9519563D0 (en) * 1995-09-26 1995-11-29 Merck Sharp & Dohme Therapeutic agents
US5808064A (en) * 1996-08-13 1998-09-15 Merck & Co., Inc. Palladium catalyzed indolization
SK17899A3 (en) 1996-08-13 2000-02-14 Merck & Co Inc Palladium catalyzed indolization
SE9704709D0 (sv) 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds
US6355641B1 (en) * 1999-03-17 2002-03-12 Syntex (U.S.A.) Llc Oxazolone derivatives and uses thereof
RU2160738C2 (ru) * 1999-03-29 2000-12-20 ООО Научно-производственное предприятие "Новые технологии" Способ получения 1,4-диазобицикло [2,2,2]октана
DE19932621A1 (de) * 1999-07-13 2001-04-26 Bayer Ag Neue substituerte alpha, beta-anellierte Butyrolactone
MY145722A (en) * 2000-04-27 2012-03-30 Abbott Lab Diazabicyclic central nervous system active agents
CA2429382A1 (en) * 2000-11-20 2002-06-06 Scios Inc. Indole-type inhibitors of p38 kinase

Also Published As

Publication number Publication date
AR035423A1 (es) 2004-05-26
RU2003121308A (ru) 2005-03-10
RU2293085C2 (ru) 2007-02-10
CN1263758C (zh) 2006-07-12
CN1489592A (zh) 2004-04-14
HUP0302538A2 (hu) 2003-11-28
HK1063629A1 (en) 2005-01-07
NO20033434L (no) 2003-09-23
KR20030074764A (ko) 2003-09-19
US20040053986A1 (en) 2004-03-18
SE0100326D0 (sv) 2001-02-02
NO20033434D0 (no) 2003-08-01
WO2002060902A1 (en) 2002-08-08
BG108035A (bg) 2003-07-28
BR0206791A (pt) 2004-01-27
UA75382C2 (en) 2006-04-17
ES2243706T3 (es) 2005-12-01
EP1360187A1 (en) 2003-11-12
PL363454A1 (en) 2004-11-15
IL156734A0 (en) 2004-02-08
NZ526992A (en) 2005-01-28
MXPA03006579A (es) 2003-09-22
DE60204755D1 (de) 2005-07-28
ATE298339T1 (de) 2005-07-15
CN1854138A (zh) 2006-11-01
SK9702003A3 (en) 2004-01-08
US7144914B2 (en) 2006-12-05
JP2004522749A (ja) 2004-07-29
CA2434970A1 (en) 2002-08-08
PT1360187E (pt) 2005-10-31
HUP0302538A3 (en) 2006-05-29
DE60204755T2 (de) 2006-05-18
EE200300364A (et) 2003-10-15
EP1360187B1 (en) 2005-06-22
MY136788A (en) 2008-11-28
ZA200305345B (en) 2004-10-11
CZ20032061A3 (cs) 2003-10-15

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