IS7660A - Nýjar bensóímídasólafleiður nytsamlegar sem andviðkomumiðlar - Google Patents

Nýjar bensóímídasólafleiður nytsamlegar sem andviðkomumiðlar

Info

Publication number
IS7660A
IS7660A IS7660A IS7660A IS7660A IS 7660 A IS7660 A IS 7660A IS 7660 A IS7660 A IS 7660A IS 7660 A IS7660 A IS 7660A IS 7660 A IS7660 A IS 7660A
Authority
IS
Iceland
Prior art keywords
antidepressants
useful
new
benzoimidazole derivatives
benzoimidazole
Prior art date
Application number
IS7660A
Other languages
English (en)
Other versions
IS2738B (is
Inventor
Charles Kath John
Peter Lyssikatos Joseph
Fay Wang Huifen
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of IS7660A publication Critical patent/IS7660A/is
Publication of IS2738B publication Critical patent/IS2738B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IS7660A 2002-08-28 2005-01-20 Tæki til þess að hreinsa bræddan málm IS2738B (is)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40652402P 2002-08-28 2002-08-28
US41704702P 2002-10-08 2002-10-08
PCT/IB2003/003634 WO2004020431A2 (en) 2002-08-28 2003-08-14 Novel benzoimidazole derivatives useful as antiproliferative agents

Publications (2)

Publication Number Publication Date
IS7660A true IS7660A (is) 2005-01-20
IS2738B IS2738B (is) 2011-06-15

Family

ID=31981411

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7660A IS2738B (is) 2002-08-28 2005-01-20 Tæki til þess að hreinsa bræddan málm

Country Status (40)

Country Link
US (1) US7071337B2 (is)
EP (1) EP1594858B1 (is)
JP (1) JP4551771B2 (is)
KR (2) KR100816166B1 (is)
CN (1) CN1319966C (is)
AP (1) AP2005003237A0 (is)
AR (1) AR041055A1 (is)
AT (1) ATE445610T1 (is)
AU (1) AU2003250499B2 (is)
BR (1) BRPI0313942C1 (is)
CA (1) CA2495577C (is)
CR (1) CR7698A (is)
CU (1) CU23413B7 (is)
CY (1) CY1110580T1 (is)
DE (1) DE60329715D1 (is)
DK (1) DK1594858T3 (is)
DO (1) DOP2003000694A (is)
EA (1) EA008448B1 (is)
EC (1) ECSP055633A (is)
ES (1) ES2333219T3 (is)
GE (1) GEP20064005B (is)
HN (1) HN2003000257A (is)
HR (1) HRP20050191B1 (is)
IL (1) IL166832A (is)
IS (1) IS2738B (is)
MA (1) MA27389A1 (is)
MX (1) MXPA05001256A (is)
MY (1) MY139357A (is)
NO (1) NO20051303L (is)
NZ (1) NZ538427A (is)
OA (1) OA12916A (is)
PA (1) PA8580301A1 (is)
PE (1) PE20050131A1 (is)
PL (1) PL377678A1 (is)
PT (1) PT1594858E (is)
RS (1) RS20050180A (is)
SI (1) SI1594858T1 (is)
TW (1) TW200407131A (is)
UY (1) UY27952A1 (is)
WO (1) WO2004020431A2 (is)

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EP1641780B1 (en) * 2003-06-24 2008-11-12 Pfizer Products Incorporated Processes for the preparation of 1- [(benzoimidazole-1yl) quinolin-8-yl] piperidin-4-ylamine derivatives
WO2005094830A1 (en) * 2004-03-30 2005-10-13 Pfizer Products Inc. Combinations of signal transduction inhibitors
GB0411421D0 (en) * 2004-05-21 2004-06-23 Glaxo Group Ltd Novel compounds
WO2006038111A1 (en) * 2004-10-07 2006-04-13 Pfizer Products Inc. Benzoimidazole derivatives useful as antiproliferative agents
CA2763671A1 (en) 2005-04-26 2006-11-02 Pfizer Inc. P-cadherin antibodies
NZ566774A (en) 2005-09-07 2011-11-25 Pfizer Human monoclonal antibodies to activin receptor-like kinase-1
EP2258700A1 (en) 2006-05-09 2010-12-08 Pfizer Products Inc. Cycloalkylamino acid derivatives and pharmaceutical compositions thereof
NZ580327A (en) 2007-04-03 2012-02-24 Array Biopharma Inc IMIDAZO[1,2-a]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS
TWI472529B (zh) * 2008-05-21 2015-02-11 Incyte Corp ２－氟－Ｎ－甲基－４－〔７－（喹啉－６－基－甲基）－咪唑并〔１，２－ｂ〕〔１，２，４〕三－２－基〕苯甲醯胺之鹽類及其相關製備方法
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
US8628554B2 (en) 2010-06-13 2014-01-14 Virender K. Sharma Intragastric device for treating obesity
US10010439B2 (en) 2010-06-13 2018-07-03 Synerz Medical, Inc. Intragastric device for treating obesity
JP6039559B2 (ja) 2010-09-02 2016-12-07 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ Ｌｐａ受容体アンタゴニストとしてのピラゾロピリジノン誘導体
GB201103578D0 (en) 2011-03-02 2011-04-13 Sabrepharm Ltd Dipyridinium derivatives
KR101738063B1 (ko) 2012-09-21 2017-05-19 아로그 파마슈티칼스, 인코퍼레이티드 구조적으로 활성인 인산화된 ｆｌｔ３ 키나제의 억제 방법
TWI599356B (zh) 2012-09-26 2017-09-21 安羅格製藥有限責任公司 抑制突變型ｃ－ｋｉｔ的方法
US10835525B2 (en) 2012-09-26 2020-11-17 Arog Pharmaceuticals, Inc. Method of inhibiting mutant C-KIT
US11642340B2 (en) 2012-09-26 2023-05-09 Arog Pharmaceuticals, Inc. Method of inhibiting mutant C-KIT
BR112015016282A2 (en) 2013-01-07 2017-07-11 Arog Pharmaceuticals, Inc. crenolanib for treatment of mutated flt3 proliferative disorders
US10463658B2 (en) 2013-10-25 2019-11-05 Videra Pharmaceuticals, Llc Method of inhibiting FLT3 kinase
TR201900148T4 (tr) * 2014-10-31 2019-02-21 Genoscience Pharma Sas Kansere karşı yeni maddeler olarak sübstitüe edilmiş 2,4 diamino-kinolin.
GB2543550A (en) 2015-10-21 2017-04-26 Hox Therapeutics Ltd Peptides
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
DK3452465T3 (da) * 2016-05-04 2021-02-08 Genoscience Pharma Substituerede 2,4-diaminoquinolinderivater til anvendelse til behandling af proliferative sygdomme
US12534764B2 (en) 2016-11-02 2026-01-27 Arog Pharmaceuticals, Inc. Crenolanib for treating FLT3 mutated proliferative disorders associated mutations
EA201991078A1 (ru) 2016-11-02 2019-11-29 Креноланиб для лечения пролиферативных расстройств, связанных с мутацией flt3
CN107382984B (zh) * 2017-08-24 2020-07-10 扬州市三药制药有限公司 一种治疗白血病药物的制备方法
CN107382983B (zh) * 2017-08-24 2020-08-07 扬州市三药制药有限公司 一种治疗白血病药物的合成方法
CN110840893A (zh) 2018-12-13 2020-02-28 安罗格制药有限责任公司 含克莱拉尼的药物组合物及其用途
US11471451B2 (en) 2019-08-19 2022-10-18 Arog Pharmaceuticals, Inc. Uses of crenolanib
CN117447376A (zh) * 2019-12-09 2024-01-26 苏州恩华生物医药科技有限公司 连双环结构sigma-1受体抑制剂
CN118767143A (zh) 2019-12-12 2024-10-15 听治疗有限责任公司 用于预防和治疗听力损失的组合物和方法
CA3186319A1 (en) * 2020-07-20 2022-01-27 Arog Pharmaceuticals, Inc. Crystal forms of crenolanib and methods of use thereof
WO2022019998A1 (en) 2020-07-20 2022-01-27 Arog Pharmaceuticals, Inc. Crystal forms of crenolanib and methods of use thereof
CN116234549B (zh) * 2020-08-05 2025-11-25 总医院公司 盐诱导激酶抑制剂
US11524006B2 (en) 2020-09-17 2022-12-13 Arog Pharmaceuticals, Inc. Crenolanib for treating TRK kinase associated proliferative disorders
US11969420B2 (en) 2020-10-30 2024-04-30 Arog Pharmaceuticals, Inc. Combination therapy of crenolanib and apoptosis pathway agents for the treatment of proliferative disorders
WO2022090547A1 (en) 2020-10-30 2022-05-05 Dsm Ip Assets B.V. Production of carotenoids by fermentation
CN113683594B (zh) * 2021-09-07 2022-12-27 曲靖师范学院 一种喹啉-苯并咪唑盐类化合物及其合成方法和应用
JP2023063189A (ja) 2021-10-22 2023-05-09 アログ・ファーマシューティカルズ・インコーポレイテッド 以前の治療に対して再発性／不応性のｆｌｔ３突然変異増殖性障害を治療するためのクレノラニブ
AU2022379973A1 (en) 2021-11-08 2024-06-27 Progentos Therapeutics, Inc. Platelet-derived growth factor receptor (pdgfr) alpha inhibitors and uses thereof
CN114409632B (zh) * 2022-02-22 2024-04-30 北京鲲达宇科技有限公司 2-取代氨基-3-苯并咪唑取代的喹啉衍生物及其制备方法与应用

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JP2008002005A (ja) * 2006-06-21 2008-01-10 Shimada Shoji Kk 衣服用パッド

Also Published As

Publication number Publication date
US20050124599A1 (en) 2005-06-09
CU23413B7 (es) 2009-09-08
DOP2003000694A (es) 2004-02-29
CY1110580T1 (el) 2015-04-29
GEP20064005B (en) 2006-12-25
WO2004020431A3 (en) 2004-05-13
MA27389A1 (fr) 2005-06-01
HRP20050191A2 (en) 2005-10-31
CR7698A (es) 2007-11-23
PT1594858E (pt) 2009-12-14
OA12916A (en) 2006-10-13
HN2003000257A (es) 2004-12-01
TW200407131A (en) 2004-05-16
CN1319966C (zh) 2007-06-06
JP4551771B2 (ja) 2010-09-29
MXPA05001256A (es) 2005-06-08
HK1078571A1 (en) 2006-03-17
KR20050036984A (ko) 2005-04-20
NZ538427A (en) 2007-04-27
AU2003250499B2 (en) 2009-04-23
ATE445610T1 (de) 2009-10-15
CN1678604A (zh) 2005-10-05
SI1594858T1 (sl) 2010-01-29
UY27952A1 (es) 2004-03-31
KR20070086768A (ko) 2007-08-27
AU2003250499A1 (en) 2004-03-19
BRPI0313942B1 (pt) 2019-06-04
AP2005003237A0 (en) 2005-03-31
EA200500174A1 (ru) 2005-08-25
JP2006501309A (ja) 2006-01-12
HRP20050191A9 (hr) 2013-11-22
IL166832A (en) 2011-03-31
IS2738B (is) 2011-06-15
EP1594858B1 (en) 2009-10-14
EP1594858A2 (en) 2005-11-16
HRP20050191B1 (hr) 2013-12-20
WO2004020431A2 (en) 2004-03-11
BRPI0313942C1 (pt) 2021-05-25
EA008448B1 (ru) 2007-06-29
PL377678A1 (pl) 2006-02-06
BR0313942A (pt) 2005-07-12
CA2495577C (en) 2010-06-15
US7071337B2 (en) 2006-07-04
RS20050180A (sr) 2007-08-03
ECSP055633A (es) 2005-04-18
CA2495577A1 (en) 2004-03-11
DK1594858T3 (da) 2009-12-14
NO20051303L (no) 2005-05-18
BRPI0313942B8 (pt) 2020-08-04
ES2333219T3 (es) 2010-02-18
PA8580301A1 (es) 2005-05-24
MY139357A (en) 2009-09-30
DE60329715D1 (de) 2009-11-26
KR100816166B1 (ko) 2008-03-21
PE20050131A1 (es) 2005-03-21
AR041055A1 (es) 2005-04-27

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