ITPD910077A1 - Procedimento per la purificazione di acido ialuronico e frazione di acido ialuronico puro per uso oftalmico. - Google Patents

Procedimento per la purificazione di acido ialuronico e frazione di acido ialuronico puro per uso oftalmico.

Info

Publication number
ITPD910077A1
ITPD910077A1 IT000077A ITPD910077A ITPD910077A1 IT PD910077 A1 ITPD910077 A1 IT PD910077A1 IT 000077 A IT000077 A IT 000077A IT PD910077 A ITPD910077 A IT PD910077A IT PD910077 A1 ITPD910077 A1 IT PD910077A1
Authority
IT
Italy
Prior art keywords
hyaluronic acid
fraction
purification
procedure
ophthalmic use
Prior art date
Application number
IT000077A
Other languages
English (en)
Inventor
Silvana Lorenzi
Aurelio Romeo
Original Assignee
Fidia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11389548&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ITPD910077(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fidia Spa filed Critical Fidia Spa
Priority to ITPD910077A priority Critical patent/IT1247175B/it
Publication of ITPD910077A0 publication Critical patent/ITPD910077A0/it
Priority to DE69230242T priority patent/DE69230242T2/de
Priority to KR1019920703262A priority patent/KR0178544B1/ko
Priority to ES92908628T priority patent/ES2092971T3/es
Priority to JP4507997A priority patent/JP2580458B2/ja
Priority to PL92297297A priority patent/PL168477B1/pl
Priority to RU92016520A priority patent/RU2128666C1/ru
Priority to CS923771A priority patent/CZ282248B6/cs
Priority to IL10161192A priority patent/IL101611A/en
Priority to AT92908628T priority patent/ATE186307T1/de
Priority to HU9204012A priority patent/HU215193B/hu
Priority to AU15766/92A priority patent/AU653022B2/en
Priority to PCT/EP1992/000861 priority patent/WO1992018543A1/en
Priority to SK3771-92A priority patent/SK280191B6/sk
Priority to BR9205240A priority patent/BR9205240A/pt
Priority to SG1996005472A priority patent/SG46515A1/en
Priority to CA002084875A priority patent/CA2084875C/en
Priority to DK92908628T priority patent/DK0535200T3/da
Priority to EP92908628A priority patent/EP0535200B1/en
Publication of ITPD910077A1 publication Critical patent/ITPD910077A1/it
Priority to NO924873A priority patent/NO305520B1/no
Priority to FI925756A priority patent/FI104973B/fi
Priority to UA93002144A priority patent/UA27229C2/uk
Publication of IT1247175B publication Critical patent/IT1247175B/it
Application granted granted Critical
Priority to IL11345395A priority patent/IL113453A0/xx
Priority to US08/439,437 priority patent/US5559104A/en
Priority to GR20000400131T priority patent/GR3032434T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ITPD910077A 1991-04-19 1991-04-19 Procedimento per la purificazione di acido ialuronico e frazione di acido ialuronico puro per uso oftalmico. IT1247175B (it)

Priority Applications (25)

Application Number Priority Date Filing Date Title
ITPD910077A IT1247175B (it) 1991-04-19 1991-04-19 Procedimento per la purificazione di acido ialuronico e frazione di acido ialuronico puro per uso oftalmico.
EP92908628A EP0535200B1 (en) 1991-04-19 1992-04-16 Procedure for the purification of hyaluronic acid and fraction of pure hyaluronic acid for ophthalmic use
AU15766/92A AU653022B2 (en) 1991-04-19 1992-04-16 Procedure for the purification of hyaluronic acid and fraction of pure hyaluronic acid for ophthalmic use
BR9205240A BR9205240A (pt) 1991-04-19 1992-04-16 Procedimento para a purificacao de acido hialuronico e fracao de acido hialuronico puro para uso oftalmico
ES92908628T ES2092971T3 (es) 1991-04-19 1992-04-16 Procedimiento para la purificacion de acido hialuronico y fraccion de acido hialuronico puro para utilizacion oftalmologica.
JP4507997A JP2580458B2 (ja) 1991-04-19 1992-04-16 ヒアルロン酸の精製方法および眼科用の純粋なヒアルロン酸の分画
PL92297297A PL168477B1 (pl) 1991-04-19 1992-04-16 Sposób otrzymywania frakcji kwasu hialuronowego, sposób otrzymywania frakcji hialuronianu sodu oraz sposób oczyszczania kwasu hialuronowego lub jego soli PL PL PL PL PL PL
RU92016520A RU2128666C1 (ru) 1991-04-19 1992-04-16 Фракция гиалуроновой кислоты или ее соли, способ очистки этой фракции, способы получения этой фракции, фармацевтический препарат и средства, используемые в офтальмологии
CS923771A CZ282248B6 (cs) 1991-04-19 1992-04-16 Způsob čištění kyseliny hyaluronové a frakce čisté kyseliny hyaluronové pro oftalmologické použití
IL10161192A IL101611A (en) 1991-04-19 1992-04-16 Process for the purification of hyaluronic acid and fraction of pure hyaluronic acid for ophthalmic use
AT92908628T ATE186307T1 (de) 1991-04-19 1992-04-16 Verfahren zur reinigung von hyaluronsäure und fraktion von reiner hyaluronsäurezur ophthalmischen verwendung.
HU9204012A HU215193B (hu) 1991-04-19 1992-04-16 Eljárás szemészeti célra alkalmazható nagy tisztaságú hialuronsav-frakció és az ezt tartalmazó gyógyszerkészítmények előállítására
DE69230242T DE69230242T2 (de) 1991-04-19 1992-04-16 Verfahren zur Reinigung von Hyaluronsäure und Fraktion von reiner Hyaluronsäurezur ophthalmischen Verwendung.
PCT/EP1992/000861 WO1992018543A1 (en) 1991-04-19 1992-04-16 Procedure for the purification of hyaluronic acid and fraction of pure hyaluronic acid for ophthalmic use
SK3771-92A SK280191B6 (sk) 1991-04-19 1992-04-16 Frakcia kyseliny hyalurónovej, spôsob výroby frakc
KR1019920703262A KR0178544B1 (ko) 1991-04-19 1992-04-16 안과용 순수 히알우론산 분류물 및 그의 정제방법
SG1996005472A SG46515A1 (en) 1991-04-19 1992-04-16 Procedure for the purification of hyaluronic acid and fraction of pure hyaluronic acid for ophthalmic use
CA002084875A CA2084875C (en) 1991-04-19 1992-04-16 Procedure for the purification of hyaluronic acid and fraction of pure hyaluronic acid for ophthalmic use
DK92908628T DK0535200T3 (da) 1991-04-19 1992-04-16 Fremgangsmåde til oprensning af hyaluronsyre og fraktion af ren hyaluronsyre til oftalmiskanvendelse
NO924873A NO305520B1 (no) 1991-04-19 1992-12-16 FremgangsmÕte til rensing av hyaluronsyre og fraksjon av ren hyaluronsyre til oftalmologisk anvendelse
FI925756A FI104973B (fi) 1991-04-19 1992-12-18 Menetelmä hyaluronihapon puhdistamiseksi
UA93002144A UA27229C2 (uk) 1991-04-19 1993-06-16 Фракція гіалуронової кислоти або її солі для застосування в офтальмології, спосіб одержання фракції натрієвої солі гіалуронової кислоти та фармацевтичний препарат для використання в офтальмології
IL11345395A IL113453A0 (en) 1991-04-19 1995-04-20 Procedure for the purification of hydraluronic acid and fraction of pure hyaluronic acid for ophthalmic use
US08/439,437 US5559104A (en) 1991-04-19 1995-05-11 Procedure for the purification of hyaluronic acid and fraction of pure hyaluronic acid for ophthalmic use
GR20000400131T GR3032434T3 (en) 1991-04-19 2000-01-19 Procedure for the purification of hyaluronic acid and fraction of pure hyaluronic acid for ophthalmic use.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITPD910077A IT1247175B (it) 1991-04-19 1991-04-19 Procedimento per la purificazione di acido ialuronico e frazione di acido ialuronico puro per uso oftalmico.

Publications (3)

Publication Number Publication Date
ITPD910077A0 ITPD910077A0 (it) 1991-04-19
ITPD910077A1 true ITPD910077A1 (it) 1992-10-19
IT1247175B IT1247175B (it) 1994-12-12

Family

ID=11389548

Family Applications (1)

Application Number Title Priority Date Filing Date
ITPD910077A IT1247175B (it) 1991-04-19 1991-04-19 Procedimento per la purificazione di acido ialuronico e frazione di acido ialuronico puro per uso oftalmico.

Country Status (24)

Country Link
US (1) US5559104A (it)
EP (1) EP0535200B1 (it)
JP (1) JP2580458B2 (it)
KR (1) KR0178544B1 (it)
AT (1) ATE186307T1 (it)
AU (1) AU653022B2 (it)
BR (1) BR9205240A (it)
CA (1) CA2084875C (it)
CZ (1) CZ282248B6 (it)
DE (1) DE69230242T2 (it)
DK (1) DK0535200T3 (it)
ES (1) ES2092971T3 (it)
FI (1) FI104973B (it)
GR (1) GR3032434T3 (it)
HU (1) HU215193B (it)
IL (2) IL101611A (it)
IT (1) IT1247175B (it)
NO (1) NO305520B1 (it)
PL (1) PL168477B1 (it)
RU (1) RU2128666C1 (it)
SG (1) SG46515A1 (it)
SK (1) SK280191B6 (it)
UA (1) UA27229C2 (it)
WO (1) WO1992018543A1 (it)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
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IT1287967B1 (it) 1996-10-17 1998-09-10 Fidia Spa In Amministrazione S Preparazioni farmaceutiche per uso anestetico locale
IT1291452B1 (it) 1997-04-14 1999-01-11 Fidia Advanced Biopolymers Srl Rivestimento a base di acido ialuronico e suoi derivati per la protezione di parti elettroniche da agenti esterni
US6919076B1 (en) 1998-01-20 2005-07-19 Pericor Science, Inc. Conjugates of agents and transglutaminase substrate linking molecules
US6958148B1 (en) 1998-01-20 2005-10-25 Pericor Science, Inc. Linkage of agents to body tissue using microparticles and transglutaminase
EP1091936B1 (en) 1998-05-29 2003-07-30 Bone Care International, Inc. Method for making hydroxy-25-ene-vitamin d compounds
DK172900B1 (da) 1998-12-18 1999-09-27 Per Julius Nielsen Præparat samt kit til brug ved intraoculære operationer
IT1306644B1 (it) 1999-04-08 2001-10-02 Fidia Advanced Biopolymers Srl Strutture tridimensionali comprendenti derivati dell'acido ialuronicoottenibili mediante la tecnica antisolvente supercritico.
RU2163123C2 (ru) * 1999-05-26 2001-02-20 Уфимский научно-исследовательский институт глазных болезней Глазные капли
RU2148404C1 (ru) * 1999-07-08 2000-05-10 Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" Фармацевтическая композиция для медикаментозного расширения зрачка в офтальмологии
RU2147876C1 (ru) * 1999-07-08 2000-04-27 Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" Фармацевтическая композиция для обезболивания в офтальмологии
RU2186786C1 (ru) * 2001-03-26 2002-08-10 Воронежская государственная технологическая академия Способ получения гиалуроновой кислоты
KR100836733B1 (ko) * 2002-11-15 2008-06-10 코오롱생명과학 주식회사 히알우론산 나트륨의 회수방법 및 그를 위한 장치
RU2234310C1 (ru) * 2003-01-21 2004-08-20 Гусева Ольга Юрьевна Способ приготовления вискоэластичного протектора эндотелия роговицы
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US20080063677A1 (en) * 2004-03-10 2008-03-13 New Life Resources, Llc Therapeutic, nutraceutical and cosmetic applications for eggshell membrane and processed eggshell membrane preparations
US20040180025A1 (en) * 2003-03-12 2004-09-16 New Life Resources, Llc Therapeutic, nutraceutical and cosmetic applications for eggshell membrane and processed eggshell membrane preparations
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RU2325902C2 (ru) * 2003-10-27 2008-06-10 Федеральное государственное учреждение "Российский научный центр "Восстановительная травматология и ортопедия" имени академика Г.А.Илизарова Федерального агентства по высокотехнологичной медицинской помощи" (ФГУ "РНЦ "ВТО" им.акад. Г.А. Илизарова Росмедтехнологий") Способ выделения гликозаминогликанов из минерализованной соединительной ткани
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KR100577075B1 (ko) * 2004-06-16 2006-05-08 주식회사 티앤라이프시스템 칼슘염 및 인산염, 또는 인산칼슘염을 이용한 히아루론산정제방법
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RU2280041C1 (ru) * 2005-04-21 2006-07-20 Общество с ограниченной ответственностью Научно-производственное предприятие "Тульская индустрия ЛТД" Способ получения водорастворимых солевых комплексов гиалуроновой кислоты (варианты)
DE102005030011A1 (de) * 2005-06-17 2006-12-21 Aesculap Ag & Co. Kg Verfahren zur Herstellung von sterilen Polysaccharidlösungen
ITPD20050242A1 (it) 2005-08-03 2007-02-04 Fidia Farmaceutici Bioconiugati antitumorali dell'acido ialuronico o dei suoi derivati, ottenibili per coniugazione chimica diretta o indiretta, e loro impiego in campo farmaceutico
ITMI20061668A1 (it) * 2006-09-01 2008-03-02 Schiena Michele Giuseppe Di Composizione a base di acido ialuronico e suoi sali per il trattamento di lesioni epiteliali
KR101509139B1 (ko) * 2006-11-23 2015-04-08 주식회사 엘지생명과학 히알루론산의 정제방법
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US8759321B2 (en) * 2007-06-13 2014-06-24 Bausch & Lomb Incorporated Ophthalmic composition with hyaluronic acid and polymeric biguanide
CN101855248B (zh) 2007-11-13 2012-08-22 生物技术通用（以色列）有限公司 用于粘弹性生物聚合物的稀释过滤灭菌方法
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US9096819B2 (en) 2008-01-31 2015-08-04 Bausch & Lomb Incorporated Ophthalmic compositions with an amphoteric surfactant and an anionic biopolymer
AU2009231634B2 (en) 2008-04-04 2014-05-15 University Of Utah Research Foundation Alkylated semi-synthetic glycosaminoglycosan ethers, and methods for making and using thereof
US20100286010A1 (en) * 2008-09-03 2010-11-11 Erning Xia Ophthalmic Compositions with Hyaluronic Acid
US20100086512A1 (en) 2008-10-02 2010-04-08 Rolf Schaefer Mucomimetic compositions and uses therefore
US20100178317A1 (en) * 2009-01-09 2010-07-15 Burke Susan E Lens Care Solutions with Hyaluronic Acid
JP5957439B2 (ja) * 2011-03-02 2016-07-27 デンカ株式会社 ヒアルロン酸またはその塩を含む水溶液
WO2012118192A1 (ja) * 2011-03-02 2012-09-07 電気化学工業株式会社 ヒアルロン酸またはその塩を含む水溶液
WO2012118194A1 (ja) * 2011-03-02 2012-09-07 電気化学工業株式会社 樹脂製バレルを有するシリンジ内にヒアルロン酸又はその塩を含む水溶液を充填してなるプレフィルドシリンジ
KR20140024862A (ko) * 2011-03-02 2014-03-03 덴키 가가쿠 고교 가부시기가이샤 히알루론산 또는 히알루론산염을 포함하는 수용액
KR20140050593A (ko) * 2011-03-02 2014-04-29 덴키 가가쿠 고교 가부시기가이샤 히알루론산 또는 히알루론산염을 포함하는 수용액
CA2830933A1 (en) 2011-03-23 2012-09-27 University Of Utah Research Foundation Methods for treating or preventing urological inflammation
RU2477138C1 (ru) * 2011-11-02 2013-03-10 Общество с ограниченной ответственностью Научно-производственное предприятие "Тульская индустрия ЛТД" Способ получения заполняющего материала для пластической хирургии и инструментальной косметологии, заполняющий материал и способ введения заполняющего материала в проблемную зону
ITMI20120664A1 (it) 2012-04-20 2013-10-21 Anika Therapeutics Srl Biomateriali a base di gellano per l'uso come filler in chirurgia
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IT201600079633A1 (it) * 2016-07-28 2018-01-28 Fidia Farm Spa Procedimento di preparazione e purificazione del sale sodico dell’acido ialuronico
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CA2084875A1 (en) 1992-10-20
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JP2580458B2 (ja) 1997-02-12
SK377192A3 (en) 1995-06-07
FI104973B (fi) 2000-05-15
ES2092971T1 (es) 1996-12-16
UA27229C2 (uk) 2000-08-15
IL101611A (en) 1996-06-18
BR9205240A (pt) 1993-08-31
HUT63186A (en) 1993-07-28
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IL113453A (en) 1995-07-31
AU1576692A (en) 1992-11-17
CZ377192A3 (en) 1993-05-12
ES2092971T3 (es) 2000-01-01
ATE186307T1 (de) 1999-11-15
SK280191B6 (sk) 1999-09-10
HU9204012D0 (en) 1993-03-29
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SG46515A1 (en) 1998-02-20
IL113453A0 (en) 1995-07-31
CA2084875C (en) 1998-01-06
FI925756A0 (fi) 1992-12-18
US5559104A (en) 1996-09-24
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NO924873L (no) 1993-02-19
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EP0535200A1 (en) 1993-04-07
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FI925756L (fi) 1992-12-18
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AU653022B2 (en) 1994-09-15
IT1247175B (it) 1994-12-12

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