JP3484190B2 - 新規シクロスポリン製剤 - Google Patents

新規シクロスポリン製剤

Info

Publication number: JP3484190B2
Authority: JP; Japan
Prior art keywords: component; composition; cyclosporin; cyclosporine; components
Prior art date: 1989-02-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

JP03134890A

Other languages

English (en)

Japanese (ja)

Other versions

JPH02235817A (ja

Inventor

ビルギット・ハウエル

ウルリッヒ・ポザンスキ

Original Assignee

ノバルティスアクチエンゲゼルシャフト

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-02-09

Filing date

1990-02-08

Publication date

2004-01-06

1989-02-09 Priority claimed from GB898902901A external-priority patent/GB8902901D0/en

1989-02-09 Priority claimed from GB898902898A external-priority patent/GB8902898D0/en

1989-02-13 Priority claimed from GB898903147A external-priority patent/GB8903147D0/en

1989-02-17 Priority claimed from GB898903663A external-priority patent/GB8903663D0/en

1990-02-08 Application filed by ノバルティスアクチエンゲゼルシャフト filed Critical ノバルティスアクチエンゲゼルシャフト

1990-09-18 Publication of JPH02235817A publication Critical patent/JPH02235817A/ja

2004-01-06 Application granted granted Critical

2004-01-06 Publication of JP3484190B2 publication Critical patent/JP3484190B2/ja

2019-01-06 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

229930182912 cyclosporin Natural products 0.000 title claims description 133
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108010036949 Cyclosporine Proteins 0.000 title claims description 122
229960001265 ciclosporin Drugs 0.000 title claims description 120
229930105110 Cyclosporin A Natural products 0.000 title claims description 60
238000002360 preparation method Methods 0.000 title description 3
239000000203 mixture Substances 0.000 claims description 164
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APSBXTVYXVQYAB-UHFFFAOYSA-M sodium docusate Chemical compound [Na+].CCCCC(CC)COC(=O)CC(S([O-])(=O)=O)C(=O)OCC(CC)CCCC APSBXTVYXVQYAB-UHFFFAOYSA-M 0.000 description 1
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239000003549 soybean oil Substances 0.000 description 1
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Classifications

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- A61K9/4841—Filling excipients; Inactive ingredients
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
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- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Molecular Biology (AREA)
Rheumatology (AREA)
Gastroenterology & Hepatology (AREA)
Diabetes (AREA)
Pain & Pain Management (AREA)
Biophysics (AREA)
Hematology (AREA)
Dermatology (AREA)
Inorganic Chemistry (AREA)
Neurology (AREA)
Tropical Medicine & Parasitology (AREA)
Transplantation (AREA)
Biochemistry (AREA)
Oil, Petroleum & Natural Gas (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Peptides Or Proteins (AREA)

JP03134890A 1989-02-09 1990-02-08 新規シクロスポリン製剤 Expired - Lifetime JP3484190B2 (ja)

Applications Claiming Priority (8)

Application Number	Priority Date	Filing Date	Title
GB898902901A GB8902901D0 (en)	1989-02-09	1989-02-09	Improvements in or relating to organic compounds
GB8902901.1		1989-02-09
GB898902898A GB8902898D0 (en)	1989-02-09	1989-02-09	Improvements in or relating to organic compounds
GB8902898.9		1989-02-09
GB898903147A GB8903147D0 (en)	1989-02-13	1989-02-13	Improvements in or relating to organic compounds
GB8903147.0		1989-02-13
GB8903663.6		1989-02-17
GB898903663A GB8903663D0 (en)	1989-02-17	1989-02-17	Improvements in or relating to organic compounds

Related Child Applications (1)

Application Number	Title	Priority Date	Filing Date
JP2001127538A Division JP4073641B2 (ja)	1989-02-09	2001-04-25	新規シクロスポリン製剤

Publications (2)

Publication Number	Publication Date
JPH02235817A JPH02235817A (ja)	1990-09-18
JP3484190B2 true JP3484190B2 (ja)	2004-01-06

Family

ID=27450262

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
JP03134890A Expired - Lifetime JP3484190B2 (ja)	1989-02-09	1990-02-08	新規シクロスポリン製剤
JP2001127538A Expired - Lifetime JP4073641B2 (ja)	1989-02-09	2001-04-25	新規シクロスポリン製剤
JP2005265724A Pending JP2006001947A (ja)	1989-02-09	2005-09-13	新規シクロスポリン製剤

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
JP2001127538A Expired - Lifetime JP4073641B2 (ja)	1989-02-09	2001-04-25	新規シクロスポリン製剤
JP2005265724A Pending JP2006001947A (ja)	1989-02-09	2005-09-13	新規シクロスポリン製剤

Country Status (25)

Country	Link
JP (3)	JP3484190B2 (da)
KR (1)	KR0170769B1 (da)
AT (1)	AT404552B (da)
AU (1)	AU630413B2 (da)
BE (1)	BE1003009A5 (da)
CA (1)	CA2009533C (da)
CH (1)	CH679277A5 (da)
CY (1)	CY1903A (da)
DE (1)	DE4003844B4 (da)
DK (1)	DK176209B1 (da)
ES (1)	ES2021942A6 (da)
FI (1)	FI97524C (da)
FR (1)	FR2642650B1 (da)
GB (1)	GB2230440B (da)
HK (1)	HK37296A (da)
HU (1)	HU213394B (da)
IT (1)	IT1240758B (da)
LU (1)	LU87675A1 (da)
MY (1)	MY107377A (da)
NL (1)	NL195028C (da)
NO (1)	NO301576B1 (da)
NZ (1)	NZ232401A (da)
PH (1)	PH30917A (da)
PT (1)	PT93079B (da)
SE (1)	SE511398C2 (da)

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GB2222770B (en) *	1988-09-16	1992-07-29	Sandoz Ltd	Pharmaceutical compositions containing cyclosporins
JPH1038029A (ja) *	1996-07-26	1998-02-13	Ebara Corp	制振機能付き円板状構造物
JPH10280435A (ja) *	1997-04-03	1998-10-20	Sekisui Chem Co Ltd	地下室の構築方法

1990
- 1990-02-05 BE BE9000133A patent/BE1003009A5/fr not_active IP Right Cessation
- 1990-02-05 CH CH359/90A patent/CH679277A5/de not_active IP Right Cessation
- 1990-02-05 FR FR9001389A patent/FR2642650B1/fr not_active Expired - Lifetime
- 1990-02-05 GB GB9002504A patent/GB2230440B/en not_active Expired - Lifetime
- 1990-02-07 FI FI900604A patent/FI97524C/fi active IP Right Grant
- 1990-02-07 NZ NZ232401A patent/NZ232401A/en unknown
- 1990-02-07 PH PH40014A patent/PH30917A/en unknown
- 1990-02-07 SE SE9000441A patent/SE511398C2/sv not_active Application Discontinuation
- 1990-02-07 DK DK199000327A patent/DK176209B1/da not_active IP Right Cessation
- 1990-02-07 LU LU87675A patent/LU87675A1/fr unknown
- 1990-02-07 CA CA002009533A patent/CA2009533C/en not_active Expired - Lifetime
- 1990-02-07 PT PT93079A patent/PT93079B/pt not_active IP Right Cessation
- 1990-02-07 NO NO900577A patent/NO301576B1/no not_active IP Right Cessation
- 1990-02-07 HU HU90701A patent/HU213394B/hu unknown
- 1990-02-07 MY MYPI90000191A patent/MY107377A/en unknown
- 1990-02-08 AT AT0027290A patent/AT404552B/de not_active IP Right Cessation
- 1990-02-08 AU AU49252/90A patent/AU630413B2/en not_active Expired
- 1990-02-08 DE DE4003844A patent/DE4003844B4/de not_active Expired - Lifetime
- 1990-02-08 KR KR1019900001492A patent/KR0170769B1/ko not_active Expired - Lifetime
- 1990-02-08 NL NL9000299A patent/NL195028C/nl not_active IP Right Cessation
- 1990-02-08 IT IT47609A patent/IT1240758B/it active IP Right Grant
- 1990-02-08 JP JP03134890A patent/JP3484190B2/ja not_active Expired - Lifetime
- 1990-02-09 ES ES9000397A patent/ES2021942A6/es not_active Expired - Lifetime
1996
- 1996-03-07 HK HK37296A patent/HK37296A/xx not_active IP Right Cessation
- 1996-11-22 CY CY190396A patent/CY1903A/en unknown
2001
- 2001-04-25 JP JP2001127538A patent/JP4073641B2/ja not_active Expired - Lifetime
2005
- 2005-09-13 JP JP2005265724A patent/JP2006001947A/ja active Pending

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Ｐｈａｒｍ．Ｒｅｓ．，Ｖｏｌ．３，Ｎｏ．１（１９８６），ｐ４８〜５１

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2005289825A (ja) *	2004-03-31	2005-10-20	Meruku Hoei Kk	シクロスポリン製剤

Also Published As

Publication number	Publication date
AU630413B2 (en)	1992-10-29
NO301576B1 (no)	1997-11-17
LU87675A1 (fr)	1991-10-08
NL195028B (nl)	2003-08-01
IT1240758B (it)	1993-12-17
GB2230440B (en)	1993-05-19
BE1003009A5 (fr)	1991-10-22
DK176209B1 (da)	2007-02-05
GB9002504D0 (en)	1990-04-04
NZ232401A (en)	1992-10-28
ES2021942A6 (es)	1991-11-16
CY1903A (en)	1996-11-22
MY107377A (en)	1995-11-30
HK37296A (en)	1996-03-15
DE4003844B4 (de)	2007-09-20
AU4925290A (en)	1990-08-16
JP4073641B2 (ja)	2008-04-09
HU900701D0 (en)	1990-04-28
JPH02235817A (ja)	1990-09-18
DK32790D0 (da)	1990-02-07
FI97524C (fi)	1997-01-10
KR0170769B1 (ko)	1999-02-01
CA2009533C (en)	2002-11-12
CH679277A5 (da)	1992-01-31
SE511398C2 (sv)	1999-09-20
IT9047609A1 (it)	1991-08-08
FR2642650B1 (fr)	1994-12-09
NO900577D0 (no)	1990-02-07
DK32790A (da)	1990-08-10
PH30917A (en)	1997-12-23
JP2001302538A (ja)	2001-10-31
KR900012625A (ko)	1990-09-01
HU213394B (en)	1997-06-30
NL195028C (nl)	2003-12-02
IT9047609A0 (it)	1990-02-08
PT93079A (pt)	1990-08-31
FI900604A0 (fi)	1990-02-07
NO900577L (no)	1990-08-10
SE9000441D0 (sv)	1990-02-07
JP2006001947A (ja)	2006-01-05
GB2230440A (en)	1990-10-24
FI97524B (fi)	1996-09-30
DE4003844A1 (de)	1990-08-16
FR2642650A1 (fr)	1990-08-10
ATA27290A (de)	1998-05-15
NL9000299A (nl)	1990-09-03
CA2009533A1 (en)	1990-08-09
SE9000441L (sv)	1991-08-08
PT93079B (pt)	1996-04-30
AT404552B (de)	1998-12-28

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Publication	Publication Date	Title
JP4073641B2 (ja)	2008-04-09	新規シクロスポリン製剤
US5756450A (en)	1998-05-26	Water soluble monoesters as solubilisers for pharmacologically active compounds and pharmaceutical excipients and novel cyclosporin galenic forms
KR100446170B1 (ko)	2004-11-20	사이클로스포린을함유하는약학조성물
JPH0611703B2 (ja)	1994-02-16	新規シクロスポリン製剤
US6187747B1 (en)	2001-02-13	Pharmaceutical composition comprising cyclosporin
EP0985412B1 (en)	2004-10-27	Cyclosporin compositions
EP1151755B1 (en)	2005-03-16	Pharmaceutical compositions comprising cyclosporin as active ingredient
US6346511B1 (en)	2002-02-12	Pharmaceutical composition comprising cyclosporin
RU2207870C2 (ru)	2003-07-10	Фармацевтическая композиция, включающая циклоспорин в качестве активного ингредиента
IE900434L (en)	1990-08-09	Novel cyclosporin galenic forms
KR100256007B1 (ko)	2000-05-01	사이클로스포린을 함유하는 약학 조성물
KR100267149B1 (ko)	2000-09-15	사이클로스포린을 함유하는 약학 조성물
CZ20012999A3 (cs)	2002-04-17	Farmaceutický prostředek obsahující cyklosporin a způsob jeho přípravy

JP3484190B2 - 新規シクロスポリン製剤 - Google Patents

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