JPH0449524B2 - - Google Patents
Info
- Publication number
- JPH0449524B2 JPH0449524B2 JP57133958A JP13395882A JPH0449524B2 JP H0449524 B2 JPH0449524 B2 JP H0449524B2 JP 57133958 A JP57133958 A JP 57133958A JP 13395882 A JP13395882 A JP 13395882A JP H0449524 B2 JPH0449524 B2 JP H0449524B2
- Authority
- JP
- Japan
- Prior art keywords
- antitumor
- acid
- daunorubicin
- complex
- arachidonic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Landscapes
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13395882A JPS5925327A (ja) | 1982-07-31 | 1982-07-31 | 抗腫瘍性複合体の製造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13395882A JPS5925327A (ja) | 1982-07-31 | 1982-07-31 | 抗腫瘍性複合体の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5925327A JPS5925327A (ja) | 1984-02-09 |
| JPH0449524B2 true JPH0449524B2 (de) | 1992-08-11 |
Family
ID=15117051
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP13395882A Granted JPS5925327A (ja) | 1982-07-31 | 1982-07-31 | 抗腫瘍性複合体の製造方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5925327A (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5994392A (en) * | 1988-02-26 | 1999-11-30 | Neuromedica, Inc. | Antipsychotic prodrugs comprising an antipsychotic agent coupled to an unsaturated fatty acid |
| US6576636B2 (en) | 1996-05-22 | 2003-06-10 | Protarga, Inc. | Method of treating a liver disorder with fatty acid-antiviral agent conjugates |
| US5795909A (en) | 1996-05-22 | 1998-08-18 | Neuromedica, Inc. | DHA-pharmaceutical agent conjugates of taxanes |
| ES2151277T3 (es) * | 1996-05-22 | 2000-12-16 | Protarga Inc | Composiciones que comprenden conjugados de acido cis-docosahexaenoico y taxotere. |
| US5919815A (en) * | 1996-05-22 | 1999-07-06 | Neuromedica, Inc. | Taxane compounds and compositions |
| JP2002538224A (ja) * | 1999-03-09 | 2002-11-12 | プロタルガ,インコーポレーテッド | 脂肪酸−抗癌剤複合体およびこの使用 |
| US7235583B1 (en) | 1999-03-09 | 2007-06-26 | Luitpold Pharmaceuticals, Inc., | Fatty acid-anticancer conjugates and uses thereof |
| EP1423107B1 (de) | 2001-03-23 | 2012-05-09 | Luitpold Pharmaceuticals, Inc. | Fettalkohol-arzneimittel-konjugate |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS535678B2 (de) * | 1973-05-30 | 1978-03-01 | ||
| JPS5014686A (de) * | 1973-06-13 | 1975-02-15 | ||
| JPS5240B2 (de) * | 1973-12-17 | 1977-01-05 | ||
| JPS5126884A (en) * | 1974-08-28 | 1976-03-05 | Asahi Chemical Ind | Nn ashiruarabinonukureoshido no seizoho |
| JPS5132573A (en) * | 1974-09-11 | 1976-03-19 | Asahi Chemical Ind | Nn ashiruarabinonukureoshido no seizohoho |
| JPS5148682A (ja) * | 1974-10-15 | 1976-04-26 | Asahi Chemical Ind | Nukureochidojudotainoseiho |
| JPS5148678A (en) * | 1974-10-15 | 1976-04-26 | Asahi Chemical Ind | n44 ashirunukureoshidono seiho |
| JPS527974A (en) * | 1975-07-08 | 1977-01-21 | Asahi Chem Ind Co Ltd | Process for preparing n4- acylcytarabines |
| JPS584718B2 (ja) * | 1976-12-23 | 1983-01-27 | 協和醗酵工業株式会社 | 新規なマイトマイシン誘導体およびその製造法ならびに新規なマイトマイシン誘導体を含有する抗腫瘍剤 |
| JPS54130517A (en) * | 1978-03-31 | 1979-10-09 | Yuuichi Yamamura | Muramyldipeptide higher fatty acid ester |
| US4291024A (en) * | 1978-04-10 | 1981-09-22 | Turcotte Joseph G | Cytotoxic liponucleotide analogs |
| JPS552602A (en) * | 1978-06-20 | 1980-01-10 | Yamasa Shoyu Co Ltd | 1-beta-d-arabinofranosylcytosine-5'-phosphoric acid oleyl ester |
| JPS552601A (en) * | 1978-06-20 | 1980-01-10 | Yamasa Shoyu Co Ltd | Anti-tumor agent for non-injection use |
| JPS5640607A (en) * | 1979-09-12 | 1981-04-16 | Asahi Chem Ind Co Ltd | Drug composition |
| JPS5692299A (en) * | 1979-12-27 | 1981-07-25 | Fuji Kagaku Kogyo Kk | 5-fluorouridine derivative and its preparation |
| JPS5810366B2 (ja) * | 1980-04-14 | 1983-02-25 | 旭化成株式会社 | 医薬組成物 |
| JPS5791994A (en) * | 1980-11-26 | 1982-06-08 | Fuji Kagaku Kogyo Kk | 5'-o-(n-alkylcarbamoylalanyl)-5-fluorouridine and its preparation |
| JPS584723A (ja) * | 1981-06-27 | 1983-01-11 | Snow Brand Milk Prod Co Ltd | 抗腫瘍剤 |
-
1982
- 1982-07-31 JP JP13395882A patent/JPS5925327A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5925327A (ja) | 1984-02-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI105155B (fi) | Menetelmä terapeuttisesti käyttökelpoisten sappihappojohdannaisten valmistamiseksi | |
| KR100221690B1 (ko) | 담즙산 유도체 및 이의 제조방법 | |
| US6030997A (en) | Acid labile prodrugs | |
| EP0004467B1 (de) | Bis-Anthracycline, Verfahren zu ihrer Herstellung und Verwendung und liposome Zusammensetzungen zur Verabreichung derselben | |
| US5466681A (en) | Receptor conjugates for targeting penicillin antibiotics to bacteria | |
| IE914567A1 (en) | Acid-labile linker molecules | |
| WO2009043296A1 (en) | Gambogic glycoside derivatives and analogs, the preparation and the application thereof | |
| US5208323A (en) | Coupling of an anti-tumor to an antibody using glutaraldehyde preactivated anti-tumor agent | |
| WO2020233174A1 (zh) | 一种抗体药物偶联物中间体的一锅法制备工艺 | |
| JPH0449524B2 (de) | ||
| CN111670053A (zh) | 一种抗体药物偶联物中间体的一锅法制备工艺 | |
| JPS6084288A (ja) | シアノキノナミンアセテ−ト類およびその製造法 | |
| EP1159756B1 (de) | Verbindungen für krebs-therapie | |
| Cassinelli et al. | Synthesis and antitumor activity of 4'-O-methyldaunorubicin, 4'-O-methyladriamycin, and their 4'-epi analogs | |
| PENCO et al. | Stereochemical requirements in the antitumor anthracyclines | |
| HU180894B (en) | Process for producing pharmaceutically acceptable salts of 3-square bracket-bracket-s-bracket closed-1-comma above-phenyl-ethyl-amino-square aracket closed-propylamino-bleomycine | |
| EP0128670A1 (de) | 4-Demethoxy-3'-deamino-3'-(4-morpholinyl)-Derivate von anthracyclinen Krebsantibiotika | |
| JPH10503509A (ja) | 8−フルオロ−アントラサイクリン類、それらの調整法及びそれらを含む薬学的組成品 | |
| CN114426538A (zh) | 一种小檗碱卡格列净衍生物及其制备方法和应用 | |
| JPH06336494A (ja) | 疎水性ビタミンb12誘導体 | |
| CN118184726A (zh) | 一种以甘草次酸衍生物为配体的铂(iv)前药的制备方法和应用 | |
| US4831019A (en) | Pharmaceutical preparations of 4-demethoxy-n-trifluoroacetyl anthracyclines | |
| CN118496288A (zh) | 一种糖基化喜树碱类化合物Gly-CPTR及其制药用途、药物或前药及制备方法 | |
| JPH034079B2 (de) | ||
| JP4246358B2 (ja) | ポリエンマクロライド系抗生物質の多量体 |