JPH05509108A - ２，４−ジオキソ−ピリド［２，３−ｄ］ピリミジン−３−酢酸及びそのエステルと塩 - Google Patents

２，４−ジオキソ−ピリド［２，３−ｄ］ピリミジン−３−酢酸及びそのエステルと塩

Info

Publication number
JPH05509108A
JPH05509108A JP4501265A JP50126592A JPH05509108A JP H05509108 A JPH05509108 A JP H05509108A JP 4501265 A JP4501265 A JP 4501265A JP 50126592 A JP50126592 A JP 50126592A JP H05509108 A JPH05509108 A JP H05509108A
Authority
JP
Japan
Prior art keywords
alkyl
chlorine
phenyl
hydrogen
bromine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4501265A
Other languages
English (en)
Japanese (ja)
Inventor
ハウアード，ハリー・アール
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of JPH05509108A publication Critical patent/JPH05509108A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
JP4501265A 1991-01-17 1991-11-05 ２，４−ジオキソ−ピリド［２，３−ｄ］ピリミジン−３−酢酸及びそのエステルと塩 Pending JPH05509108A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US642,600 1984-08-20
US64260091A 1991-01-17 1991-01-17

Publications (1)

Publication Number Publication Date
JPH05509108A true JPH05509108A (ja) 1993-12-16

Family

ID=24577255

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4501265A Pending JPH05509108A (ja) 1991-01-17 1991-11-05 ２，４−ジオキソ−ピリド［２，３−ｄ］ピリミジン−３−酢酸及びそのエステルと塩

Country Status (7)

Country Link
EP (1) EP0568540A1 (pt)
JP (1) JPH05509108A (pt)
CA (1) CA2100164A1 (pt)
FI (1) FI933244A0 (pt)
IE (1) IE920120A1 (pt)
PT (1) PT100013A (pt)
WO (1) WO1992012979A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW299333B (pt) * 1992-12-29 1997-03-01 Takeda Pharm Industry Co Ltd
CN104725376A (zh) * 2015-03-31 2015-06-24 山东友帮生化科技有限公司 6-氯-8-羧基咪唑并[1,2-a]吡啶的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1401549A (en) * 1972-07-07 1975-07-16 Hisamitsu Pharmaceutical Co Pyrido-2,3-d-pyrimidine-2,4-1h,3h- diones and methods of preparing them

Also Published As

Publication number Publication date
WO1992012979A1 (en) 1992-08-06
FI933244A7 (fi) 1993-07-16
FI933244L (fi) 1993-07-16
IE920120A1 (en) 1992-07-29
EP0568540A1 (en) 1993-11-10
PT100013A (pt) 1993-01-29
CA2100164A1 (en) 1992-07-18
FI933244A0 (fi) 1993-07-16

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