JPH0578382A - 硫酸化アルキルオリゴ糖またはその生理学的に許容される塩およびこれを有効成分とする抗ウイルス剤 - Google Patents

硫酸化アルキルオリゴ糖またはその生理学的に許容される塩およびこれを有効成分とする抗ウイルス剤

Info

Publication number
JPH0578382A
JPH0578382A JP3211833A JP21183391A JPH0578382A JP H0578382 A JPH0578382 A JP H0578382A JP 3211833 A JP3211833 A JP 3211833A JP 21183391 A JP21183391 A JP 21183391A JP H0578382 A JPH0578382 A JP H0578382A
Authority
JP
Japan
Prior art keywords
oligosaccharide
virus
sulfated
antiviral agent
agent according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP3211833A
Other languages
English (en)
Japanese (ja)
Inventor
Tadao Shoji
忠生 東海林
Naoya Ikushima
直也 生島
Naoko Takahashi
菜穂子 高橋
要 ▲かつら▼谷
Kaname Katsuraya
Hideji Nishibashi
秀治 西橋
Toshiyuki Uryu
敏之 瓜生
Takashi Yoshida
吉田　　孝
Naoki Yamamoto
直樹 山本
Hideki Nakajima
秀喜 中島
Shiro Shigeta
士郎 茂田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DIC Corp
Original Assignee
Dainippon Ink and Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Ink and Chemicals Co Ltd filed Critical Dainippon Ink and Chemicals Co Ltd
Priority to EP19910914756 priority Critical patent/EP0497988A4/en
Priority to CA002071915A priority patent/CA2071915A1/fr
Priority to JP3211833A priority patent/JPH0578382A/ja
Priority to PCT/JP1991/001122 priority patent/WO1992003453A1/fr
Priority to AU83346/91A priority patent/AU644895B2/en
Publication of JPH0578382A publication Critical patent/JPH0578382A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Polymers & Plastics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
JP3211833A 1990-08-23 1991-08-23 硫酸化アルキルオリゴ糖またはその生理学的に許容される塩およびこれを有効成分とする抗ウイルス剤 Withdrawn JPH0578382A (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP19910914756 EP0497988A4 (en) 1990-08-23 1991-08-23 Antiviral agent
CA002071915A CA2071915A1 (fr) 1990-08-23 1991-08-23 Agent antiviral
JP3211833A JPH0578382A (ja) 1990-08-23 1991-08-23 硫酸化アルキルオリゴ糖またはその生理学的に許容される塩およびこれを有効成分とする抗ウイルス剤
PCT/JP1991/001122 WO1992003453A1 (fr) 1990-08-23 1991-08-23 Agent antiviral
AU83346/91A AU644895B2 (en) 1990-08-23 1991-08-23 Antiviral agent

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
JP22218790 1990-08-23
JP22830690 1990-08-31
JP22830790 1990-08-31
JP23564990 1990-09-07
JP33571390 1990-11-30
JP3-99050 1991-04-30
JP9905091 1991-04-30
JP2-222187 1991-04-30
JP2-235649 1991-04-30
JP2-335713 1991-04-30
JP2-228307 1991-04-30
JP2-228306 1991-04-30
JP3211833A JPH0578382A (ja) 1990-08-23 1991-08-23 硫酸化アルキルオリゴ糖またはその生理学的に許容される塩およびこれを有効成分とする抗ウイルス剤

Publications (1)

Publication Number Publication Date
JPH0578382A true JPH0578382A (ja) 1993-03-30

Family

ID=27565622

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3211833A Withdrawn JPH0578382A (ja) 1990-08-23 1991-08-23 硫酸化アルキルオリゴ糖またはその生理学的に許容される塩およびこれを有効成分とする抗ウイルス剤

Country Status (5)

Country Link
EP (1) EP0497988A4 (fr)
JP (1) JPH0578382A (fr)
AU (1) AU644895B2 (fr)
CA (1) CA2071915A1 (fr)
WO (1) WO1992003453A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5504207A (en) * 1994-10-18 1996-04-02 Abbott Laboratories Process and intermediate for the preparation of terazosin hydrochloride dihydrate
JPH11504018A (ja) * 1995-04-28 1999-04-06 ジ・オーストラリアン・ナショナル・ユニバーシティ 硫酸化オリゴ糖の製造および使用

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459257A (en) * 1993-01-11 1995-10-17 Dainippon Ink And Chemicals, Inc. Sulfated oligoglycoside acylate and antiviral agent containing the same as active ingredient
SE9401826D0 (sv) * 1994-05-27 1994-05-27 Pharmacia Ab Anti-Helicobacter pyroli substance
US20020165168A1 (en) * 1995-12-16 2002-11-07 Joachim Bunger Use of sugar derivatives as antimicrobial, antimycotic and/or antiviral active substances
JP4532618B2 (ja) * 1999-02-25 2010-08-25 株式会社グライコメディクス 新規糖鎖プライマー
PL225045B1 (pl) 2012-05-18 2017-02-28 Univ Jagiellonski Zastosowanie polimeru chitozanowego do wytwarzania leków do leczenia i profilaktyki infekcji wywołanych przez koronawirusy
CN103275239B (zh) * 2013-06-14 2015-06-17 西北师范大学 非伯羟基取代的硫酸化多糖的合成方法
EP3846853A1 (fr) 2018-09-04 2021-07-14 Ecole Polytechnique Federale De Lausanne (Epfl) Nanoparticules virucides et leur utilisation contre le virus de la grippe

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1951784A (en) 1931-07-13 1934-03-20 Bohme H Th Ag Process of preparing esters
DE3601136A1 (de) 1986-01-16 1987-07-23 Max Planck Gesellschaft Hemmstoffe der reversen transkriptase fuer prophylaxe und therapie von retrovirus-infektionen in saeugetieren
US4806275A (en) 1986-09-05 1989-02-21 A. E. Staley Manufacturing Company Ionic derivatives of alkyl mono and polyglycosides
EP0293826A3 (fr) * 1987-06-02 1989-05-10 Stichting REGA V.Z.W. Application thérapeutique et prophylactique des polysaccharides sulfatés contre le SIDA
JP2626892B2 (ja) 1987-07-07 1997-07-02 味の素株式会社 新規な抗ウィルス剤
EP0338092A1 (fr) * 1987-10-30 1989-10-25 Chugai Seiyaku Kabushiki Kaisha Agent anti-vih
DE3834911A1 (de) * 1988-10-13 1990-04-19 Huels Chemische Werke Ag Verfahren zur sulfatierung von alkyloligoglycosiden
JP2956090B2 (ja) * 1989-10-30 1999-10-04 大日本インキ化学工業株式会社 オリゴ糖誘導体
JPH03145425A (ja) * 1989-10-30 1991-06-20 Dainippon Ink & Chem Inc 抗ウィルス剤

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5504207A (en) * 1994-10-18 1996-04-02 Abbott Laboratories Process and intermediate for the preparation of terazosin hydrochloride dihydrate
JPH11504018A (ja) * 1995-04-28 1999-04-06 ジ・オーストラリアン・ナショナル・ユニバーシティ 硫酸化オリゴ糖の製造および使用

Also Published As

Publication number Publication date
AU644895B2 (en) 1993-12-23
EP0497988A1 (fr) 1992-08-12
AU8334691A (en) 1992-03-17
EP0497988A4 (en) 1993-03-10
CA2071915A1 (fr) 1992-02-24
WO1992003453A1 (fr) 1992-03-05

Similar Documents

Publication Publication Date Title
Hu et al. Synthesis of 3-O-sulfonated heparan sulfate octasaccharides that inhibit the herpes simplex virus type 1 host–cell interaction
Nishimura et al. Regioselective syntheses of sulfated polysaccharides: specific anti-HIV-1 activity of novel chitin sulfates
Yoshida et al. Synthesis of curdlan sulfates having inhibitory effects in vitro against AIDS viruses HIV-1 and HIV-2
TW520376B (en) Synthetic polysaccharides, process for their preparation and pharmaceutical compositions containing them
CN103788141B (zh) 硫酸化寡聚糖衍生物
AU652036B2 (en) Sulfated tocopheryl oligosaccharides and antiviral agents including the same as active ingredients
Zhou et al. Stereoselective synthesis of a sulfated tetrasaccharide corresponding to a rare sequence in the galactofucan isolated from Sargassum polycystum
TW548279B (en) Synthetic polysaccharides, process for their preparation and pharmaceutical compositions containing them
JPH0578382A (ja) 硫酸化アルキルオリゴ糖またはその生理学的に許容される塩およびこれを有効成分とする抗ウイルス剤
Katsuraya et al. Synthesis of sulfated alkyl malto-and laminara-oligosaccharides with potent inhibitory effects on AIDS virus infection
Vis et al. 1, 5-Anhydro-β-D-ribofuranose and the “Monoacetone Anhydroriboses” of Levene and Stiller
Katsuraya et al. Synthesis of sulfated alkyl laminara-oligosaccharides having potent anti-HIV activity and the relationship between structure and biological activities
Pareek et al. Glycosyl esters as stable donors in chemical glycosylation
CN1428345A (zh) 制备天麻素及其类似酚性糖甙式（i）的化学合成工艺
US6060597A (en) Cyclic oligosaccharide, and an agent containing the same for preventing or treating retroviral diseases
JPH09183789A (ja) 新規な硫酸化及び燐酸化糖誘導体、その製法及び用途
EP0338092A1 (fr) Agent anti-vih
JPH05139980A (ja) 持続性抗ウイルス液剤
Kamiya et al. Glycosides and Oligosaccharides in the l-Rhamnose Series: Part II. Syntheses of Certain α-l-Rhamnosyl Disaccharides
JPH05279381A (ja) 硫酸化オリゴ糖芳香族配糖体
DE69614552T2 (de) MODIFIZIERTE ALPHA-D-GLCP-(1,2)-ALPHA-D-Glcp-(1,3)-ALPHA-D-Glcp-ANALOGE
EP0830365B1 (fr) Analogues kojibiosides modifies
JPH06345652A (ja) 抗ヘルペスウイルス剤
JPH08217785A (ja) 硫酸化フルオロアルキルラミナリペンタオシド及びそれを有効成分とする抗ウイルス剤
JPH06256373A (ja) 硫酸化オリゴ糖配糖体アシル化物およびこれを有効成分とする抗ウイルス剤

Legal Events

Date Code Title Description
A300 Withdrawal of application because of no request for examination

Free format text: JAPANESE INTERMEDIATE CODE: A300

Effective date: 19981112