JPH078872B2 - 新規なテトラシクロ化合物およびその製造法 - Google Patents

新規なテトラシクロ化合物およびその製造法

Info

Publication number
JPH078872B2
JPH078872B2 JP63-325492A JP32549288A JPH078872B2 JP H078872 B2 JPH078872 B2 JP H078872B2 JP 32549288 A JP32549288 A JP 32549288A JP H078872 B2 JPH078872 B2 JP H078872B2
Authority
JP
Japan
Prior art keywords
group
tetradeca
oxa
diazatetracyclo
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP63-325492A
Other languages
English (en)
Japanese (ja)
Other versions
JPH078872B1 (da
Inventor
正信 向阪
紘 寺野
忠昭 小森
盛太 石見
道雄 山下
眞志 橋本
逸郎 内田
茂弘 高瀬
Original Assignee
藤沢薬品工業株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848416141A external-priority patent/GB8416141D0/en
Priority claimed from GB858510378A external-priority patent/GB8510378D0/en
Application filed by 藤沢薬品工業株式会社 filed Critical 藤沢薬品工業株式会社
Publication of JPH078872B2 publication Critical patent/JPH078872B2/ja
Publication of JPH078872B1 publication Critical patent/JPH078872B1/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
    • C12R1/465—

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP63-325492A 1984-06-25 1985-06-25 新規なテトラシクロ化合物およびその製造法 Expired - Lifetime JPH078872B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB848416141A GB8416141D0 (en) 1984-06-25 1984-06-25 Fr-900482 substance
GB8416141 1984-06-25
GB858510378A GB8510378D0 (en) 1985-04-24 1985-04-24 Tetracyclo compounds
GB8510378 1985-04-24

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP60140084A Division JPS6110590A (ja) 1984-06-25 1985-06-25 ジアザテトラシクロ化合物を含有する抗腫瘍剤

Publications (2)

Publication Number Publication Date
JPH078872B2 true JPH078872B2 (ja) 1995-02-01
JPH078872B1 JPH078872B1 (da) 1995-02-01

Family

ID=26287918

Family Applications (3)

Application Number Title Priority Date Filing Date
JP63-325492A Expired - Lifetime JPH078872B2 (ja) 1984-06-25 1985-06-25 新規なテトラシクロ化合物およびその製造法
JP63325492A Pending JPH01199975A (ja) 1984-06-25 1988-12-22 新規なテトラシクロ化合物およびその製造法
JP6122707A Expired - Lifetime JPH07102128B2 (ja) 1984-06-25 1994-06-03 ストレプトミセス・サンダエンシスの生物学的純粋培養物

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP63325492A Pending JPH01199975A (ja) 1984-06-25 1988-12-22 新規なテトラシクロ化合物およびその製造法
JP6122707A Expired - Lifetime JPH07102128B2 (ja) 1984-06-25 1994-06-03 ストレプトミセス・サンダエンシスの生物学的純粋培養物

Country Status (9)

Country Link
US (2) US4645765A (da)
EP (1) EP0166389B1 (da)
JP (3) JPH078872B2 (da)
KR (1) KR920009527B1 (da)
AU (1) AU584097B2 (da)
CA (1) CA1248897A (da)
DE (1) DE3577850D1 (da)
DK (1) DK170892B1 (da)
ES (2) ES8703477A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK733888A (da) * 1988-01-12 1989-07-13 Fujisawa Pharmaceutical Co Stabiliseringsmiddel
US4973693A (en) * 1989-09-01 1990-11-27 Shunsuke Goto Novel pentacyclic compound and stereoselective synthesis thereof
CA2270181A1 (en) 1996-10-29 1998-05-07 Fujisawa Pharmaceutical Co., Ltd. Novel process for preparing fr900482 and compounds analogous thereto
JP2003171280A (ja) * 1999-06-07 2003-06-17 Fujisawa Pharmaceut Co Ltd 抗腫瘍効果増強剤
AU2001262731A1 (en) * 2000-06-20 2002-01-02 Fujisawa Pharmaceutical Co. Ltd. Tetracyclic compounds-containing pharmaceutical preparations
KR100768476B1 (ko) 2005-11-24 2007-10-18 한국해양연구원 항암물질을 생산하는 방선균 스트렙토마이세스 속 균주,이의 분리방법, 이로부터 반고형 추출물을 제조하는 방법,이로부터 유래한 반고형 추출물 및 이를 이용한 항암제조성물
US9896457B2 (en) 2013-08-29 2018-02-20 Op Bio Factory Co., Ltd. Microbial product having antifungal activity
CN111793015B (zh) * 2020-07-14 2021-08-27 遵义医科大学 一种含氮三元环化合物Strepmycin A及其分离方法和抗菌应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB974168A (en) * 1961-06-26 1964-11-04 Ici Ltd Manufacture of 2-ª‰-methoxyethylpyridine
US4313935A (en) * 1979-03-05 1982-02-02 Fujisawa Pharmaceutical Co., Ltd. Antibiotic FR-900129 substance, a process for the preparation thereof and pharmaceutical compositions containing the same
JPS56128774A (en) * 1980-03-14 1981-10-08 Microbial Chem Res Found New physiologically active substance ebelactone and its preparation

Also Published As

Publication number Publication date
EP0166389A1 (en) 1986-01-02
US4645765A (en) 1987-02-24
JPH0767623A (ja) 1995-03-14
ES552029A0 (es) 1987-09-01
ES544482A0 (es) 1987-02-16
DK285585D0 (da) 1985-06-24
AU584097B2 (en) 1989-05-18
ES8707961A1 (es) 1987-09-01
CA1248897A (en) 1989-01-17
JPH078872B1 (da) 1995-02-01
EP0166389B1 (en) 1990-05-23
KR920009527B1 (ko) 1992-10-17
DK285585A (da) 1985-12-26
DK170892B1 (da) 1996-03-04
JPH07102128B2 (ja) 1995-11-08
JPH01199975A (ja) 1989-08-11
AU4372885A (en) 1986-01-02
DE3577850D1 (de) 1990-06-28
US4743555A (en) 1988-05-10
KR860000385A (ko) 1986-01-28
ES8703477A1 (es) 1987-02-16

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