JPS5524134A - 2-phenyl-substituted-1-phthalazone derivative - Google Patents

2-phenyl-substituted-1-phthalazone derivative

Info

Publication number: JPS5524134A
Authority: JP; Japan
Prior art keywords: compound; alkyl; phthalazone; phenyl; substituted
Prior art date: 1978-08-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP9718678A

Other languages

English (en)

Japanese (ja)

Inventor

Masayuki Ishikawa

Masao Eguchi

Hiromichi Tanaka

Shigeru Ito

Yoshimi Takashima

Masahiko Kobayashi

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Individual

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-08-11

Filing date

1978-08-11

Publication date

1980-02-21

1978-08-11 Application filed by Individual filed Critical Individual

1978-08-11 Priority to JP9718678A priority Critical patent/JPS5524134A/ja

1979-08-07 Priority to US06/064,368 priority patent/US4293553A/en

1979-08-08 Priority to CA000333350A priority patent/CA1135697A/fr

1979-08-08 Priority to AU49712/79A priority patent/AU4971279A/en

1979-08-09 Priority to SE7906681A priority patent/SE7906681L/xx

1979-08-09 Priority to DE19792932259 priority patent/DE2932259A1/de

1979-08-10 Priority to GB7927986A priority patent/GB2030136B/en

1979-08-10 Priority to IT25069/79A priority patent/IT1163698B/it

1979-08-10 Priority to ES483317A priority patent/ES483317A1/es

1979-08-10 Priority to NL7906138A priority patent/NL7906138A/nl

1979-08-10 Priority to FR7920485A priority patent/FR2433017A1/fr

1979-08-10 Priority to BE0/196682A priority patent/BE878185A/fr

1980-02-21 Publication of JPS5524134A publication Critical patent/JPS5524134A/ja

Status Pending legal-status Critical Current

Links

125000000217 alkyl group Chemical group 0.000 abstract 4
150000001875 compounds Chemical class 0.000 abstract 3
125000003545 alkoxy group Chemical group 0.000 abstract 2
YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 abstract 1
206010061216 Infarction Diseases 0.000 abstract 1
208000007536 Thrombosis Diseases 0.000 abstract 1
230000004520 agglutination Effects 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
229940114079 arachidonic acid Drugs 0.000 abstract 1
235000021342 arachidonic acid Nutrition 0.000 abstract 1
UORVGPXVDQYIDP-UHFFFAOYSA-N borane Chemical compound B UORVGPXVDQYIDP-UHFFFAOYSA-N 0.000 abstract 1
229910010277 boron hydride Inorganic materials 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
150000001735 carboxylic acids Chemical class 0.000 abstract 1
230000000747 cardiac effect Effects 0.000 abstract 1
NLFBCYMMUAKCPC-KQQUZDAGSA-N ethyl (e)-3-[3-amino-2-cyano-1-[(e)-3-ethoxy-3-oxoprop-1-enyl]sulfanyl-3-oxoprop-1-enyl]sulfanylprop-2-enoate Chemical compound CCOC(=O)\C=C\SC(=C(C#N)C(N)=O)S\C=C\C(=O)OCC NLFBCYMMUAKCPC-KQQUZDAGSA-N 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
230000003301 hydrolyzing effect Effects 0.000 abstract 1
230000007574 infarction Effects 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
208000031225 myocardial ischemia Diseases 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

JP9718678A 1978-08-11 1978-08-11 2-phenyl-substituted-1-phthalazone derivative Pending JPS5524134A (en)

Priority Applications (12)

Application Number	Priority Date	Filing Date	Title
JP9718678A JPS5524134A (en)	1978-08-11	1978-08-11	2-phenyl-substituted-1-phthalazone derivative
US06/064,368 US4293553A (en)	1978-08-11	1979-08-07	1-Phthalazone derivatives, and use thereof
CA000333350A CA1135697A (fr)	1978-08-11	1979-08-08	Derives du 1-phthalazone, procede de preparation et utilisation
AU49712/79A AU4971279A (en)	1978-08-11	1979-08-08	1-phthalazone derivatives
SE7906681A SE7906681L (sv)	1978-08-11	1979-08-09	Ftalazonderivat
DE19792932259 DE2932259A1 (de)	1978-08-11	1979-08-09	1-phthalazonderivate, verfahren zu ihrer herstellung und ihre verwendung
GB7927986A GB2030136B (en)	1978-08-11	1979-08-10	1-phthalazone derivatives and acid addition salts their preparation and compositions containing them
IT25069/79A IT1163698B (it)	1978-08-11	1979-08-10	Derivati di 1-ftalazone, procedimento per la loro preparazione, e loro impiego
ES483317A ES483317A1 (es)	1978-08-11	1979-08-10	Un procedimiento para obtener derivados de 1-ftalazona
NL7906138A NL7906138A (nl)	1978-08-11	1979-08-10	1-ftalazonderivaten, werkwijzen ter bereiding daarvan, alsmede farmaceutische preparaten die deze verbinding als actieve component bevatten.
FR7920485A FR2433017A1 (fr)	1978-08-11	1979-08-10	Derives de la phtalazone-1 et medicaments qui en contiennent
BE0/196682A BE878185A (fr)	1978-08-11	1979-08-10	Derives de 1-phtalazone, leur procede de preparation et leur utilisation

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP9718678A JPS5524134A (en)	1978-08-11	1978-08-11	2-phenyl-substituted-1-phthalazone derivative

Publications (1)

Publication Number	Publication Date
JPS5524134A true JPS5524134A (en)	1980-02-21

Family

ID=14185542

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP9718678A Pending JPS5524134A (en)	1978-08-11	1978-08-11	2-phenyl-substituted-1-phthalazone derivative

Country Status (2)

Country	Link
JP (1)	JPS5524134A (fr)
BE (1)	BE878185A (fr)

1978
- 1978-08-11 JP JP9718678A patent/JPS5524134A/ja active Pending
1979
- 1979-08-10 BE BE0/196682A patent/BE878185A/fr not_active IP Right Cessation

Also Published As

Publication number	Publication date
BE878185A (fr)	1980-02-11

Publication	Publication Date	Title
JPS5278848A (en)	1977-07-02	Preparation of novel propionic acid ester derivatives
JPS54119494A (en)	1979-09-17	Preparation of cephalosporin compound
JPS5524134A (en)	1980-02-21	2-phenyl-substituted-1-phthalazone derivative
JPS51136679A (en)	1976-11-26	Process for preparing 5-((2-halogeno-1-hydroxy) alkyl) carbostyril der ivatives
JPS554323A (en)	1980-01-12	2-phenyl-substituted-1-phthalazone derivative
JPS54103846A (en)	1979-08-15	Production of cyclohexenecarboxylic acid derivative, intermediate for anti-allergic drug and surfactant
JPS54160335A (en)	1979-12-19	Preparation of alkylated hydroxybenzoic ester
JPS5553247A (en)	1980-04-18	Novel benzylamine derivative
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JPS5436274A (en)	1979-03-16	Preparation of propiophenone derivative
JPS5210291A (en)	1977-01-26	Process for preparing thienopyridine carboxylic acid derivatives
JPS5533433A (en)	1980-03-08	Production of 6-nucleoside derivative
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JPS55120591A (en)	1980-09-17	Phosphinoethylmalonic acid derivative, and preparation thereof
JPS5781454A (en)	1982-05-21	Preparation of cysteamine mineral acid salt
JPS5531029A (en)	1980-03-05	Preparation of 4-substituted amido-3-arylamino-5- pyrazolones
JPS51125239A (en)	1976-11-01	Process for preparing new bytyrophenone derivatives
JPS5527111A (en)	1980-02-27	Preparation of cephapirin
JPS5618985A (en)	1981-02-23	Furoindole compound
JPS56164153A (en)	1981-12-17	Novel desacylvalypepsidin derivative and its preparation
JPS5687584A (en)	1981-07-16	Preparation of 7-methoxycephem compound
JPS5585590A (en)	1980-06-27	Novel heterocyclic compound
JPS5772963A (en)	1982-05-07	Alpha-(2-pyridyl)arylacetaldehyde
GB1368276A (en)	1974-09-25	Thiophene carboxylic acid derivatives
JPS5246037A (en)	1977-04-12	Process for preparation of 2-(p-isobutylphenyl)propionic acid