JPS5636475A - 55phenyll22hydroxytetrahydrofurans - Google Patents

55phenyll22hydroxytetrahydrofurans

Info

Publication number: JPS5636475A
Authority: JP; Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP6515480A

Other languages

English (en)

Inventor

Matsukoowan Ueruchi Ji Uiraado

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

PFIZER

Original Assignee

PFIZER

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-01-23

Filing date

1980-05-16

Publication date

1981-04-09

1980-05-16 Application filed by PFIZER filed Critical PFIZER

1981-04-09 Publication of JPS5636475A publication Critical patent/JPS5636475A/ja

Status Pending legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/20—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Neurology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Anesthesiology (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Furan Compounds (AREA)

JP6515480A 1979-01-23 1980-05-16 55phenyll22hydroxytetrahydrofurans Pending JPS5636475A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/005,698 US4224329A (en)	1979-01-23	1979-01-23	2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles

Publications (1)

Publication Number	Publication Date
JPS5636475A true JPS5636475A (en)	1981-04-09

Family

ID=21717248

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
JP561180A Granted JPS55100386A (en)	1979-01-23	1980-01-21	22substituteddtranss55aryll2344a59bb hexahydroo1hhpyrido433bindoles
JP55065153A Expired JPS5855151B2 (ja)	1979-01-23	1980-05-16	トランス−５−アリ−ル−２，３，４，４ａ，５，９ｂ−ヘキサヒドロ−１Ｈ−ピリド〔４，３−ｂ〕インド−ル類の分割方法
JP6515580A Pending JPS5636487A (en)	1979-01-23	1980-05-16	Dextrorotatory transs55aryll2344a59bb hexahydroo1hhpyrido433bindoles
JP6515480A Pending JPS5636475A (en)	1979-01-23	1980-05-16	55phenyll22hydroxytetrahydrofurans

Family Applications Before (3)

Application Number	Title	Priority Date	Filing Date
JP561180A Granted JPS55100386A (en)	1979-01-23	1980-01-21	22substituteddtranss55aryll2344a59bb hexahydroo1hhpyrido433bindoles
JP55065153A Expired JPS5855151B2 (ja)	1979-01-23	1980-05-16	トランス−５−アリ−ル−２，３，４，４ａ，５，９ｂ−ヘキサヒドロ−１Ｈ−ピリド〔４，３−ｂ〕インド−ル類の分割方法
JP6515580A Pending JPS5636487A (en)	1979-01-23	1980-05-16	Dextrorotatory transs55aryll2344a59bb hexahydroo1hhpyrido433bindoles

Country Status (34)

Country	Link
US (1)	US4224329A (ja)
JP (4)	JPS55100386A (ja)
KR (1)	KR830001932A (ja)
AR (1)	AR231291A1 (ja)
AT (1)	AT376674B (ja)
AU (1)	AU521986B2 (ja)
BE (1)	BE881283A (ja)
CA (1)	CA1144168A (ja)
CH (2)	CH651040A5 (ja)
CS (4)	CS221806B2 (ja)
DD (2)	DD149071A5 (ja)
DE (1)	DE3002367A1 (ja)
DK (1)	DK25580A (ja)
EG (1)	EG14767A (ja)
FI (1)	FI800179A7 (ja)
FR (3)	FR2447379A1 (ja)
GB (1)	GB2041925B (ja)
GR (1)	GR73567B (ja)
HU (3)	HU189174B (ja)
IE (1)	IE49500B1 (ja)
IL (1)	IL59189A (ja)
IN (1)	IN153300B (ja)
IT (1)	IT1149927B (ja)
LU (1)	LU82105A1 (ja)
NL (1)	NL8000385A (ja)
NO (2)	NO151895C (ja)
NZ (3)	NZ197582A (ja)
PH (4)	PH15736A (ja)
PL (4)	PL120774B1 (ja)
PT (1)	PT70724A (ja)
SE (3)	SE441358B (ja)
SU (3)	SU1168094A3 (ja)
YU (2)	YU269379A (ja)
ZA (1)	ZA796374B (ja)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4337250A (en) *	1979-07-30	1982-06-29	Pfizer Inc.	Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
US4432978A (en) *	1979-07-30	1984-02-21	Pfizer Inc.	Hexahydro-trans-pyridoindole
US4431649A (en) *	1979-07-30	1984-02-14	Pfizer Inc.	Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
US4431646A (en) *	1979-07-30	1984-02-14	Pfizer Inc.	Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
US4427679A (en)	1981-01-16	1984-01-24	Pfizer Inc.	Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
US4467090A (en) *	1982-09-30	1984-08-21	Pfizer Inc.	Compound, 8-fluoro-5-(p-fluorophenyl)-2-[4-(p-fluorophenyl)-4-hydroxybutyryl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
US4477669A (en) *	1982-09-30	1984-10-16	Pfizer Inc.	Processes and intermediates useful in the preparation of flutroline
US4451655A (en) *	1982-05-17	1984-05-29	Pfizer Inc.	Process for preparing carboline derivatives and compounds used in their preparation
US4698444A (en) *	1982-09-30	1987-10-06	Pfizer Inc.	1,1-bis(p-fluorophenyl)urea
US4568748A (en) *	1982-09-30	1986-02-04	Pfizer Inc.	2-Carbobenzoxy-8-fluoro-5-(p-fluorophenyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
JPS61248502A (ja) *	1985-04-26	1986-11-05	Pioneer Electronic Corp	磁性材料の接合方法
US4636563A (en) *	1985-09-16	1987-01-13	American Home Products Corporation	Antipsychotic γ-carbolines
US4672117A (en) *	1985-09-16	1987-06-09	American Home Products Corporation	Antipsychotic gamma-carbolines
US4798896A (en) *	1988-01-19	1989-01-17	American Home Products Corporation	Antipsychotic gamma-carboline N-oxides
US5075315A (en) *	1990-05-17	1991-12-24	Mcneilab, Inc.	Antipsychotic hexahydro-2H-indeno[1,2-c]pyridine derivatives
JP4717216B2 (ja) *	1998-12-21	2011-07-06	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	α２−アンタゴニストとしてのベンズイソキサゾールおよびフェノン類
RU2329044C1 (ru) *	2006-11-16	2008-07-20	Андрей Александрович Иващенко	Лиганды 5-ht6 рецепторов, фармацевтическая композиция, способ ее получения и лекарственное средство

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA551241A (en) *		1958-01-07	S. Abbott Leslie	Production of substituted piperidines
US3382250A (en) *	1966-12-07	1968-05-07	Abbott Lab	Aroylalkyl derivatives of 1, 2, 3, 4-tetrahydro-5h-pyrido[4, 3b]indoles
US3687961A (en) *	1971-05-03	1972-08-29	Abbott Lab	8-fluoro-2-{8 3-(4-fluorophenylanilinopropyl{9 -gamma-carboline
AR205452A1 (es) *	1973-12-06	1976-05-07	Endo Lab	Metodo para preparar nuevos trans-2, 3, 4, 4a, 5, 9b-hexahidro-5-fenil-1h-pirido(4,3-b) indoles
JPS50126699A (ja) *	1974-03-20	1975-10-04
US4001263A (en) *	1974-04-01	1977-01-04	Pfizer Inc.	5-Aryl-1,2,3,4-tetrahydro-γ-carbolines
AR206812A1 (es) *	1974-04-01	1976-08-23	Pfizer	Compuestos intermediarios de azaciclo(3,4-a)indoles 4- y 5-fenil substituidos desprovistos de actividad terapeutica
SE7702301L (sv) *	1976-04-08	1977-10-09	Endo Lab	Trans-hexahydro-pyrido-indoler
SE441448B (sv) *	1977-05-23	1985-10-07	Pfizer	Sett att framstella hexahydro-gamma-karbolinforeningar

1979
- 1979-01-23 US US06/005,698 patent/US4224329A/en not_active Expired - Lifetime
- 1979-10-17 IN IN726/DEL/79A patent/IN153300B/en unknown
- 1979-10-22 PH PH23203A patent/PH15736A/en unknown
- 1979-11-05 YU YU02693/79A patent/YU269379A/xx unknown
- 1979-11-19 EG EG668/79D patent/EG14767A/xx active
- 1979-11-20 NZ NZ197582A patent/NZ197582A/en unknown
- 1979-11-20 NZ NZ192175A patent/NZ192175A/en unknown
- 1979-11-20 AR AR278965A patent/AR231291A1/es active
- 1979-11-20 NZ NZ197581A patent/NZ197581A/en unknown
- 1979-11-23 ZA ZA00796374A patent/ZA796374B/xx unknown
- 1979-12-28 NO NO794317A patent/NO151895C/no unknown
1980
- 1980-01-03 CS CS8098A patent/CS221806B2/cs unknown
- 1980-01-03 CS CS815712A patent/CS221809B2/cs unknown
- 1980-01-03 CS CS815710A patent/CS221807B2/cs unknown
- 1980-01-03 CS CS815711A patent/CS221808B2/cs unknown
- 1980-01-04 HU HU822858A patent/HU189174B/hu unknown
- 1980-01-04 SU SU802865803A patent/SU1168094A3/ru active
- 1980-01-04 HU HU8023A patent/HU184712B/hu unknown
- 1980-01-04 HU HU822859A patent/HU188201B/hu unknown
- 1980-01-07 PL PL1980221248A patent/PL120774B1/pl unknown
- 1980-01-07 PL PL1980231005A patent/PL126032B1/pl unknown
- 1980-01-07 PL PL1980231006A patent/PL126532B1/pl unknown
- 1980-01-07 PL PL1980231004A patent/PL126867B1/pl unknown
- 1980-01-15 GB GB8001232A patent/GB2041925B/en not_active Expired
- 1980-01-15 SE SE8000329A patent/SE441358B/sv unknown
- 1980-01-18 CA CA000343988A patent/CA1144168A/en not_active Expired
- 1980-01-21 GR GR60998A patent/GR73567B/el unknown
- 1980-01-21 CH CH456/80A patent/CH651040A5/fr not_active IP Right Cessation
- 1980-01-21 AU AU54765/80A patent/AU521986B2/en not_active Ceased
- 1980-01-21 CH CH5785/83A patent/CH648314A5/fr not_active IP Right Cessation
- 1980-01-21 JP JP561180A patent/JPS55100386A/ja active Granted
- 1980-01-22 FR FR8001301A patent/FR2447379A1/fr active Granted
- 1980-01-22 FI FI800179A patent/FI800179A7/fi not_active Application Discontinuation
- 1980-01-22 IL IL59189A patent/IL59189A/xx unknown
- 1980-01-22 IE IE121/80A patent/IE49500B1/en unknown
- 1980-01-22 IT IT19373/80A patent/IT1149927B/it active
- 1980-01-22 AT AT0033380A patent/AT376674B/de not_active IP Right Cessation
- 1980-01-22 DK DK25580A patent/DK25580A/da not_active Application Discontinuation
- 1980-01-22 NL NL8000385A patent/NL8000385A/nl not_active Application Discontinuation
- 1980-01-22 BE BE0/199065A patent/BE881283A/fr not_active IP Right Cessation
- 1980-01-22 DD DD80218578A patent/DD149071A5/de unknown
- 1980-01-22 LU LU82105A patent/LU82105A1/fr unknown
- 1980-01-22 KR KR1019800000225A patent/KR830001932A/ko not_active Ceased
- 1980-01-23 PT PT70724A patent/PT70724A/pt unknown
- 1980-01-23 DE DE19803002367 patent/DE3002367A1/de not_active Ceased
- 1980-05-16 JP JP55065153A patent/JPS5855151B2/ja not_active Expired
- 1980-05-16 JP JP6515580A patent/JPS5636487A/ja active Pending
- 1980-05-16 JP JP6515480A patent/JPS5636475A/ja active Pending
- 1980-05-28 FR FR8011815A patent/FR2453174A1/fr active Granted
- 1980-05-28 FR FR8011816A patent/FR2453175A1/fr active Granted
- 1980-06-17 PH PH24153A patent/PH15072A/en unknown
- 1980-06-17 PH PH24155A patent/PH15086A/en unknown
- 1980-06-17 PH PH24154A patent/PH17773A/en unknown
1981
- 1981-01-22 DD DD22761181A patent/DD156369A5/de unknown
- 1981-01-26 SU SU813233005A patent/SU1080746A3/ru active
- 1981-01-26 SU SU813233012A patent/SU1333239A3/ru active
1983
- 1983-12-13 YU YU02421/83A patent/YU242183A/xx unknown
1984
- 1984-07-27 NO NO843041A patent/NO843041L/no unknown
- 1984-09-11 SE SE8404555A patent/SE8404555L/xx not_active Application Discontinuation
- 1984-09-11 SE SE8404554A patent/SE8404554D0/xx unknown

Also Published As

Publication number	Publication date
PH15736A (en)	1983-03-18
FR2453175A1 (fr)	1980-10-31
AR231291A1 (es)	1984-10-31
JPS5855151B2 (ja)	1983-12-08
PL126532B1 (en)	1983-08-31
AU5476580A (en)	1980-07-31
KR830001932A (ko)	1983-05-19
SE8404555D0 (sv)	1984-09-11
SU1333239A3 (ru)	1987-08-23
ZA796374B (en)	1980-11-26
NZ197581A (en)	1984-05-31
JPS5636486A (en)	1981-04-09
SE8404554L (sv)	1984-09-11
JPS5636487A (en)	1981-04-09
IE800121L (en)	1980-07-23
IL59189A (en)	1984-01-31
DD156369A5 (de)	1982-08-18
CS221807B2 (en)	1983-04-29
YU242183A (en)	1984-06-30
NO151895B (no)	1985-03-18
PH15086A (en)	1982-07-02
CH651040A5 (fr)	1985-08-30
SE8404555L (sv)	1984-09-11
CS221808B2 (en)	1983-04-29
IE49500B1 (en)	1985-10-16
ATA33380A (de)	1984-05-15
DD149071A5 (de)	1981-06-24
GB2041925B (en)	1982-10-20
FR2447379A1 (fr)	1980-08-22
IN153300B (ja)	1984-06-30
AU521986B2 (en)	1982-05-13
JPS5740151B2 (ja)	1982-08-25
FR2447379B1 (ja)	1983-08-19
EG14767A (en)	1985-12-31
DE3002367A1 (de)	1980-07-24
SE441358B (sv)	1985-09-30
NZ197582A (en)	1984-05-31
SU1080746A3 (ru)	1984-03-15
FR2453175B1 (ja)	1983-07-29
HU189174B (en)	1986-06-30
PT70724A (en)	1980-02-01
FI800179A7 (fi)	1981-01-01
SU1168094A3 (ru)	1985-07-15
NO794317L (no)	1980-07-24
PL120774B1 (en)	1982-03-31
PL126867B1 (en)	1983-09-30
PL126032B1 (en)	1983-07-30
FR2453174A1 (fr)	1980-10-31
NZ192175A (en)	1984-05-31
SE8404554D0 (sv)	1984-09-11
CA1144168A (en)	1983-04-05
GB2041925A (en)	1980-09-17
PL221248A1 (ja)	1980-12-01
NO843041L (no)	1980-07-24
FR2453174B1 (ja)	1983-07-29
PH17773A (en)	1984-12-11
LU82105A1 (fr)	1980-08-08
IT8019373A0 (it)	1980-01-22
DK25580A (da)	1980-07-24
YU269379A (en)	1984-04-30
HU184712B (en)	1984-10-29
GR73567B (ja)	1984-03-16
CS221809B2 (en)	1983-04-29
NL8000385A (nl)	1980-07-25
JPS55100386A (en)	1980-07-31
PH15072A (en)	1982-06-03
IT1149927B (it)	1986-12-10
NO151895C (no)	1985-06-26
CH648314A5 (fr)	1985-03-15
CS221806B2 (en)	1983-04-29
SE8000329L (sv)	1980-07-24
IL59189A0 (en)	1980-05-30
BE881283A (fr)	1980-07-22
AT376674B (de)	1984-12-27
US4224329A (en)	1980-09-23
HU188201B (en)	1986-03-28

Publication	Publication Date	Title
EP0031257A3 (en)	1981-11-18	Pyridylanilines
CS216180A2 (en)	1984-12-14	Zpusob vyroby oplatek
EP0021287A3 (en)	1981-02-04	Multi-microprocessorsystem
CS375080A2 (en)	1985-08-15	Vstrikovaci cerpadlo
CS486180A2 (en)	1985-09-17	Zpusob vyroby n-fosfonomethylglycinu
CS458380A2 (en)	1985-06-13	Zpusob vyroby tripeptidamidu
CS819480A2 (en)	1985-09-17	Bezpecnostni lyzarske vazani
DE3064894D1 (en)	1983-10-27	Fire-guard
CS265980A1 (en)	1985-07-16	Zpusob torkretovani vyzdivky hutnich agregatu rozptylovym kuzelem
CS458480A2 (en)	1985-05-15	Zpusob vyroby tripeptidamidu
CS819380A2 (en)	1985-08-15	Deskove bezpecnostni lyzarske vazani
DE3060490D1 (en)	1982-07-22	Trialkoxysilylthiopropionamides
DE3062361D1 (en)	1983-04-21	17-cycloalkylmethyl-6-methylene-morphinane-derivatives
EP0030685A3 (en)	1981-09-09	17-cyclopropylmethyl-3-methoxy-14-hydroxy-morphinan-6-one
CU21117A3 (es)	1988-02-15	De-a-steroids
CS634381A1 (en)	1984-11-19	Zpusob ziskani esteru
CS175679A2 (en)	1985-06-13	Vodovaha
HK18685A (en)	1985-03-22	Fibrescope
CA45704S (en)	1979-07-23	Citruspress
CA46370S (en)	1979-12-17	Sun-hole/windscreen - i
CA46371S (en)	1979-12-17	Sun-hole/windscreen - iii
CA44955S (en)	1979-02-05	Citruspress
GB2060878B (en)	1983-11-16	Explosimeter
CA46372S (en)	1979-12-17	Sun-hole/windscreen-ii
CS370879A2 (en)	1988-07-15	Herbicidni prostredek