JPS6411618B2 - - Google Patents

Info

Publication number: JPS6411618B2
Authority: JP; Japan
Prior art keywords: acid; athlete; foot; triglyceride; present
Prior art date: 1979-09-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

JP11723279A

Other languages

English (en)

Japanese (ja)

Other versions

JPS5643211A (en

Inventor

Masatsugu Yamashita

Yoshihito Kadoma

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

NOF Corp

Original Assignee

Nippon Oil and Fats Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-09-14

Filing date

1979-09-14

Publication date

1989-02-27

1979-09-14 Application filed by Nippon Oil and Fats Co Ltd filed Critical Nippon Oil and Fats Co Ltd

1979-09-14 Priority to JP11723279A priority Critical patent/JPS5643211A/ja

1981-04-21 Publication of JPS5643211A publication Critical patent/JPS5643211A/ja

1989-02-27 Publication of JPS6411618B2 publication Critical patent/JPS6411618B2/ja

Status Granted legal-status Critical Current

Links

BWMISRWJRUSYEX-SZKNIZGXSA-N terbinafine hydrochloride Chemical compound Cl.C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 BWMISRWJRUSYEX-SZKNIZGXSA-N 0.000 claims description 20
201000004647 tinea pedis Diseases 0.000 claims description 20
239000003814 drug Substances 0.000 claims description 10
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerol Natural products OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 9
-1 glycerin ester Chemical class 0.000 claims description 9
235000011187 glycerol Nutrition 0.000 claims description 7
150000001732 carboxylic acid derivatives Chemical class 0.000 claims description 5
229940124597 therapeutic agent Drugs 0.000 claims description 5
125000004432 carbon atom Chemical group C* 0.000 claims description 3
239000004480 active ingredient Substances 0.000 claims description 2
UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 19
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 6
239000003795 chemical substances by application Substances 0.000 description 5
229940079593 drug Drugs 0.000 description 5
208000024891 symptom Diseases 0.000 description 5
FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 description 4
GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 description 4
XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 description 4
POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 4
FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 description 4
FBUKVWPVBMHYJY-UHFFFAOYSA-N nonanoic acid Chemical compound CCCCCCCCC(O)=O FBUKVWPVBMHYJY-UHFFFAOYSA-N 0.000 description 4
WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 4
SZHOJFHSIKHZHA-UHFFFAOYSA-N tridecanoic acid Chemical compound CCCCCCCCCCCCC(O)=O SZHOJFHSIKHZHA-UHFFFAOYSA-N 0.000 description 4
ZDPHROOEEOARMN-UHFFFAOYSA-N undecanoic acid Chemical compound CCCCCCCCCCC(O)=O ZDPHROOEEOARMN-UHFFFAOYSA-N 0.000 description 4
NQPDZGIKBAWPEJ-UHFFFAOYSA-N valeric acid Chemical compound CCCCC(O)=O NQPDZGIKBAWPEJ-UHFFFAOYSA-N 0.000 description 4
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
208000002474 Tinea Diseases 0.000 description 3
241000893966 Trichophyton verrucosum Species 0.000 description 3
230000000844 anti-bacterial effect Effects 0.000 description 3
150000001735 carboxylic acids Chemical class 0.000 description 3
239000002904 solvent Substances 0.000 description 3
OBETXYAYXDNJHR-SSDOTTSWSA-M (2r)-2-ethylhexanoate Chemical compound CCCC[C@@H](CC)C([O-])=O OBETXYAYXDNJHR-SSDOTTSWSA-M 0.000 description 2
239000005632 Capric acid (CAS 334-48-5) Substances 0.000 description 2
239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 description 2
239000005639 Lauric acid Substances 0.000 description 2
239000005643 Pelargonic acid Substances 0.000 description 2
206010040880 Skin irritation Diseases 0.000 description 2
241000223238 Trichophyton Species 0.000 description 2
239000002253 acid Substances 0.000 description 2
OBETXYAYXDNJHR-UHFFFAOYSA-N alpha-ethylcaproic acid Natural products CCCCC(CC)C(O)=O OBETXYAYXDNJHR-UHFFFAOYSA-N 0.000 description 2
239000003925 fat Substances 0.000 description 2
235000019197 fats Nutrition 0.000 description 2
MNWFXJYAOYHMED-UHFFFAOYSA-N heptanoic acid Chemical compound CCCCCCC(O)=O MNWFXJYAOYHMED-UHFFFAOYSA-N 0.000 description 2
KQNPFQTWMSNSAP-UHFFFAOYSA-N isobutyric acid Chemical compound CC(C)C(O)=O KQNPFQTWMSNSAP-UHFFFAOYSA-N 0.000 description 2
229960002446 octanoic acid Drugs 0.000 description 2
239000003883 ointment base Substances 0.000 description 2
235000019260 propionic acid Nutrition 0.000 description 2
IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 2
DCBSHORRWZKAKO-UHFFFAOYSA-N rac-1-monomyristoylglycerol Chemical compound CCCCCCCCCCCCCC(=O)OCC(O)CO DCBSHORRWZKAKO-UHFFFAOYSA-N 0.000 description 2
YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
230000036556 skin irritation Effects 0.000 description 2
231100000475 skin irritation Toxicity 0.000 description 2
241000894007 species Species 0.000 description 2
229940005605 valeric acid Drugs 0.000 description 2
KMZHZAAOEWVPSE-UHFFFAOYSA-N 2,3-dihydroxypropyl acetate Chemical compound CC(=O)OCC(O)CO KMZHZAAOEWVPSE-UHFFFAOYSA-N 0.000 description 1
TWJNQYPJQDRXPH-UHFFFAOYSA-N 2-cyanobenzohydrazide Chemical compound NNC(=O)C1=CC=CC=C1C#N TWJNQYPJQDRXPH-UHFFFAOYSA-N 0.000 description 1
OAOABCKPVCUNKO-UHFFFAOYSA-N 8-methyl Nonanoic acid Chemical compound CC(C)CCCCCCC(O)=O OAOABCKPVCUNKO-UHFFFAOYSA-N 0.000 description 1
208000010201 Exanthema Diseases 0.000 description 1
241000233866 Fungi Species 0.000 description 1
235000021360 Myristic acid Nutrition 0.000 description 1
TUNFSRHWOTWDNC-UHFFFAOYSA-N Myristic acid Natural products CCCCCCCCCCCCCC(O)=O TUNFSRHWOTWDNC-UHFFFAOYSA-N 0.000 description 1
208000002193 Pain Diseases 0.000 description 1
235000019482 Palm oil Nutrition 0.000 description 1
208000003251 Pruritus Diseases 0.000 description 1
241000130764 Tinea Species 0.000 description 1
239000003242 anti bacterial agent Substances 0.000 description 1
229940088710 antibiotic agent Drugs 0.000 description 1
OGBUMNBNEWYMNJ-UHFFFAOYSA-N batilol Chemical class CCCCCCCCCCCCCCCCCCOCC(O)CO OGBUMNBNEWYMNJ-UHFFFAOYSA-N 0.000 description 1
229960000686 benzalkonium chloride Drugs 0.000 description 1
CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 description 1
KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 1
239000004327 boric acid Substances 0.000 description 1
229960002645 boric acid Drugs 0.000 description 1
239000003240 coconut oil Substances 0.000 description 1
235000019864 coconut oil Nutrition 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
238000004042 decolorization Methods 0.000 description 1
238000004332 deodorization Methods 0.000 description 1
230000000249 desinfective effect Effects 0.000 description 1
235000014113 dietary fatty acids Nutrition 0.000 description 1
230000000694 effects Effects 0.000 description 1
238000005886 esterification reaction Methods 0.000 description 1
230000003203 everyday effect Effects 0.000 description 1
201000005884 exanthem Diseases 0.000 description 1
229930195729 fatty acid Natural products 0.000 description 1
239000000194 fatty acid Substances 0.000 description 1
150000004665 fatty acids Chemical class 0.000 description 1
MNWFXJYAOYHMED-UHFFFAOYSA-M heptanoate Chemical compound CCCCCCC([O-])=O MNWFXJYAOYHMED-UHFFFAOYSA-M 0.000 description 1
KMILVCHILLACMZ-UHFFFAOYSA-N hexanoic acid octanoic acid Chemical compound CCCCCC(O)=O.CCCCCCCC(O)=O.CCCCCCCC(O)=O KMILVCHILLACMZ-UHFFFAOYSA-N 0.000 description 1
230000007803 itching Effects 0.000 description 1
239000007788 liquid Substances 0.000 description 1
QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
229910052753 mercury Inorganic materials 0.000 description 1
239000002480 mineral oil Substances 0.000 description 1
235000010446 mineral oil Nutrition 0.000 description 1
239000000203 mixture Substances 0.000 description 1
231100000344 non-irritating Toxicity 0.000 description 1
LKFMLCZIYNBOJR-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O.CCCCCCCC(O)=O.CCCCCCCC(O)=O LKFMLCZIYNBOJR-UHFFFAOYSA-N 0.000 description 1
230000009965 odorless effect Effects 0.000 description 1
235000014593 oils and fats Nutrition 0.000 description 1
239000002540 palm oil Substances 0.000 description 1
FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
239000012188 paraffin wax Substances 0.000 description 1
230000024241 parasitism Effects 0.000 description 1
230000037368 penetrate the skin Effects 0.000 description 1
IUGYQRQAERSCNH-UHFFFAOYSA-N pivalic acid Chemical compound CC(C)(C)C(O)=O IUGYQRQAERSCNH-UHFFFAOYSA-N 0.000 description 1
239000011148 porous material Substances 0.000 description 1
230000001681 protective effect Effects 0.000 description 1
206010037844 rash Diseases 0.000 description 1
239000002994 raw material Substances 0.000 description 1
238000007670 refining Methods 0.000 description 1
229960001860 salicylate Drugs 0.000 description 1
YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 description 1
229960004889 salicylic acid Drugs 0.000 description 1
239000007787 solid Substances 0.000 description 1
230000001954 sterilising effect Effects 0.000 description 1
210000000106 sweat gland Anatomy 0.000 description 1
239000012209 synthetic fiber Substances 0.000 description 1
229920002994 synthetic fiber Polymers 0.000 description 1
TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 description 1
230000001225 therapeutic effect Effects 0.000 description 1
231100000331 toxic Toxicity 0.000 description 1
230000002588 toxic effect Effects 0.000 description 1
150000003626 triacylglycerols Chemical class 0.000 description 1
229940099259 vaseline Drugs 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
239000001993 wax Substances 0.000 description 1

Landscapes

Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

JP11723279A 1979-09-14 1979-09-14 Remedy for athlete's foot Granted JPS5643211A (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
JP11723279A JPS5643211A (en)	1979-09-14	1979-09-14	Remedy for athlete's foot

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP11723279A JPS5643211A (en)	1979-09-14	1979-09-14	Remedy for athlete's foot

Publications (2)

Publication Number	Publication Date
JPS5643211A JPS5643211A (en)	1981-04-21
JPS6411618B2 true JPS6411618B2 (fr)	1989-02-27

Family

ID=14706648

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP11723279A Granted JPS5643211A (en)	1979-09-14	1979-09-14	Remedy for athlete's foot

Country Status (1)

Country	Link
JP (1)	JPS5643211A (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5832817A (ja) *	1981-08-18	1983-02-25	Nippon Oil & Fats Co Ltd	水虫用軟膏基剤組成物
JPH0639376B2 (ja) *	1984-09-17	1994-05-25	花王株式会社	外用抗真菌剤
JPH08175989A (ja) *	1994-12-26	1996-07-09	Nissan Gosei Kogyo Kk	乳房炎の予防のための組成物
US20050058673A1 (en)	2003-09-09	2005-03-17	3M Innovative Properties Company	Antimicrobial compositions and methods
BRPI0608690B8 (pt)	2005-03-10	2021-05-25	3M Innovative Properties Co	uso de uma composição antimicrobiana
BRPI0608691A2 (pt)	2005-03-10	2010-12-07	3M Innovative Properties Company	composição antimicrobiana, e, métodos para matar ou inativar microorganismos em tecido da mucosa de um mamìfero, para tratar uma lesão ou ferimento infectado, para descolonização de microorganismos, para proporcionar eficácia antimicrobiana residual sobre uma superfìcie e para tratar uma condição

1979
- 1979-09-14 JP JP11723279A patent/JPS5643211A/ja active Granted

Also Published As

Publication number	Publication date
JPS5643211A (en)	1981-04-21

Publication	Publication Date	Title
DE3856018D1 (de)	1997-10-09	Verwendung von einer Disaccharidpolysulfat-Aluminium Verbindung zur Herstellung eines Medikaments zur Behandlung von HÄMORRHOIDEN und zur Wundheilung
CA1330945C (fr)	1994-07-26	Compositions pharmaceutiques et cosmetiques a base de peroxyde de benzoyle et de salicylates lipophiles d'ammonium quaternaires et leur utilisation, notamment dans le traitement de l'acne
JPH0759511B2 (ja)	1995-06-28	非外力的な爪の除去のための製剤およびその製造方法
US20100137222A1 (en)	2010-06-03	Basic Peptides and Their Use as Combined Antibacterial-Antifungine Agents
SE8001599L (sv)	1980-12-14	Transdermalt medicineringssystem for isosorbiddinitrat
RU2339362C2 (ru)	2008-11-27	Продукт для ухода за кожей, содержащий жирные кислоты таллового масла и растительные масла, для сухой и шелушащейся кожи и лечения псориаза, дерматита и экземы
JPS6411618B2 (fr)	1989-02-27
RU98101105A (ru)	1999-12-10	Новое применение в медицинских целях
CN1280495A (zh)	2001-01-17	二醇与α羟基酸的混合物在治疗角化过度性皮肤病中的用途
KR940003551A (ko)	1994-03-12	W-3다불포화산 에스테르를 함유한 신규 약제 조성물 및 이들을 병변 국소 치료용으로 사용하는 방법
CN111093611B (zh)	2024-03-12	用于在降低或预防体味时应用的短杆菌素及其制剂
RU2088214C1 (ru)	1997-08-27	Бальзамическое средство для местного применения, обладающее антимикробным, противовоспалительным и болеутоляющим действием
JP3142559B2 (ja)	2001-03-07	止痒剤としての血小板活性化因子拮抗剤の用途
FR2513879A1 (fr)	1983-04-08	Compositions permettant de combattre les mefaits et les inconvenients de la transpiration
WO2023150790A3 (fr)	2023-10-26	Nouveaux inhibiteurs mpro du sars-cov-2 hautement sélectifs
JPH1179988A (ja)	1999-03-23	抗真菌剤
JP2002097137A (ja)	2002-04-02	パーキンソン病の予防および／または治療剤
FR2380778A1 (fr)	1978-09-15	Compositions pharmaceutiques contenant des acides oxaniliques substitues ou leurs esters
US5006557A (en)	1991-04-09	Acne solution
JPS6293225A (ja)	1987-04-28	消炎鎮痛剤
JPS59184125A (ja)	1984-10-19	抗糸状菌剤
JP3979689B2 (ja)	2007-09-19	アセチルサリチル酸含有皮膚損傷治療剤
RU2742879C1 (ru)	2021-02-11	Фармацевтическая композиция для лечения псориаза
SE8104657L (sv)	1982-02-05	Injicerbara farmaceutiska kompositioner
KR950031040A (ko)	1995-12-18	의약