JPS6477A - 1,4-disubstituted piperazine compound - Google Patents
1,4-disubstituted piperazine compoundInfo
- Publication number
- JPS6477A JPS6477A JP63064884A JP6488488A JPS6477A JP S6477 A JPS6477 A JP S6477A JP 63064884 A JP63064884 A JP 63064884A JP 6488488 A JP6488488 A JP 6488488A JP S6477 A JPS6477 A JP S6477A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound expressed
- paf
- disease
- caused
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- -1 1,4-disubstituted piperazine compound Chemical class 0.000 title 1
- HVAUUPRFYPCOCA-AREMUKBSSA-N 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCCOC[C@@H](OC(C)=O)COP([O-])(=O)OCC[N+](C)(C)C HVAUUPRFYPCOCA-AREMUKBSSA-N 0.000 abstract 4
- 108010003541 Platelet Activating Factor Proteins 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 201000010099 disease Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- URHMVOHVYWFEAG-UHFFFAOYSA-N (2,3-dimethoxy-8,9-dihydro-7h-benzo[7]annulen-6-yl)-[4-(3,4,5-trimethoxybenzoyl)piperazin-1-yl]methanone Chemical compound C=1C=2C=C(OC)C(OC)=CC=2CCCC=1C(=O)N(CC1)CCN1C(=O)C1=CC(OC)=C(OC)C(OC)=C1 URHMVOHVYWFEAG-UHFFFAOYSA-N 0.000 abstract 1
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 208000007107 Stomach Ulcer Diseases 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 238000006482 condensation reaction Methods 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- 201000005917 gastric ulcer Diseases 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002813 thiocarbonyl group Chemical group *C(*)=S 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63064884A JPS6477A (en) | 1987-03-24 | 1988-03-17 | 1,4-disubstituted piperazine compound |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62-69804 | 1987-03-24 | ||
| JP6980487 | 1987-03-24 | ||
| JP63064884A JPS6477A (en) | 1987-03-24 | 1988-03-17 | 1,4-disubstituted piperazine compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH0177A JPH0177A (ja) | 1989-01-05 |
| JPS6477A true JPS6477A (en) | 1989-01-05 |
Family
ID=26406012
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63064884A Pending JPS6477A (en) | 1987-03-24 | 1988-03-17 | 1,4-disubstituted piperazine compound |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6477A (ja) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04364156A (ja) * | 1990-11-30 | 1992-12-16 | Fujirebio Inc | ナフトエ酸誘導体 |
| JP2005538968A (ja) * | 2002-06-29 | 2005-12-22 | ツェンタリス ゲゼルシャフト ミット ベシュレンクテル ハフツング | アリール−及びヘテロアリールカルボニルピペラジン及び良性及び悪性の腫瘍疾患を治療するためのその使用 |
| KR20220142387A (ko) * | 2021-04-14 | 2022-10-21 | 주식회사 엘지화학 | 스핑고신-1-인산 수용체 효능제 합성을 위한 중간체의 제조방법 |
-
1988
- 1988-03-17 JP JP63064884A patent/JPS6477A/ja active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04364156A (ja) * | 1990-11-30 | 1992-12-16 | Fujirebio Inc | ナフトエ酸誘導体 |
| JP2005538968A (ja) * | 2002-06-29 | 2005-12-22 | ツェンタリス ゲゼルシャフト ミット ベシュレンクテル ハフツング | アリール−及びヘテロアリールカルボニルピペラジン及び良性及び悪性の腫瘍疾患を治療するためのその使用 |
| KR20220142387A (ko) * | 2021-04-14 | 2022-10-21 | 주식회사 엘지화학 | 스핑고신-1-인산 수용체 효능제 합성을 위한 중간체의 제조방법 |
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