LT1933821T - Šoninės grandinės variantai redoks aktyviųjų terapijos priemonių, skirtų mitochondrinių ligų ir kitokių būklių gydymui ir energijos biologinių žymenų moduliavimui - Google Patents
Šoninės grandinės variantai redoks aktyviųjų terapijos priemonių, skirtų mitochondrinių ligų ir kitokių būklių gydymui ir energijos biologinių žymenų moduliavimuiInfo
- Publication number
- LT1933821T LT1933821T LTEP06814749.5T LT06814749T LT1933821T LT 1933821 T LT1933821 T LT 1933821T LT 06814749 T LT06814749 T LT 06814749T LT 1933821 T LT1933821 T LT 1933821T
- Authority
- LT
- Lithuania
- Prior art keywords
- redox
- modulation
- treatment
- conditions
- energy biomarkers
- Prior art date
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- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
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- C07C37/07—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by conversion of non-aromatic six-membered rings or of such rings formed in situ into aromatic six-membered rings, e.g. by dehydrogenation with simultaneous reduction of C=O group in that ring
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C46/00—Preparation of quinones
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C46/00—Preparation of quinones
- C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
- C07C46/06—Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07C50/02—Quinones with monocyclic quinoid structure
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- C—CHEMISTRY; METALLURGY
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- C07C50/02—Quinones with monocyclic quinoid structure
- C07C50/06—Quinones with monocyclic quinoid structure with unsaturation outside the quinoid structure
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- Health & Medical Sciences (AREA)
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- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Communicable Diseases (AREA)
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- Heart & Thoracic Surgery (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71767805P | 2005-09-15 | 2005-09-15 | |
| PCT/US2006/036052 WO2007035496A1 (en) | 2005-09-15 | 2006-09-15 | Tail variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT1933821T true LT1933821T (lt) | 2020-11-10 |
Family
ID=37637229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP06814749.5T LT1933821T (lt) | 2005-09-15 | 2006-09-15 | Šoninės grandinės variantai redoks aktyviųjų terapijos priemonių, skirtų mitochondrinių ligų ir kitokių būklių gydymui ir energijos biologinių žymenų moduliavimui |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7432305B2 (lt) |
| EP (1) | EP1933821B1 (lt) |
| JP (5) | JP2009508867A (lt) |
| CA (1) | CA2622523C (lt) |
| CY (1) | CY1123740T1 (lt) |
| DK (1) | DK1933821T3 (lt) |
| EA (1) | EA021818B1 (lt) |
| ES (1) | ES2823728T3 (lt) |
| HU (1) | HUE052377T2 (lt) |
| LT (1) | LT1933821T (lt) |
| PL (1) | PL1933821T3 (lt) |
| PT (1) | PT1933821T (lt) |
| SI (1) | SI1933821T1 (lt) |
| WO (1) | WO2007035496A1 (lt) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005033092A1 (en) | 2003-09-19 | 2005-04-14 | Galileo Pharmaceuticals, Inc. | Chroman derivatives |
| EP2471530B1 (en) | 2005-06-01 | 2017-01-11 | Edison Pharmaceuticals, Inc. | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
| US9050005B2 (en) | 2005-08-25 | 2015-06-09 | Synapse Biomedical, Inc. | Method and apparatus for transgastric neurostimulation |
| CA2622523C (en) | 2005-09-15 | 2014-02-18 | Edison Pharmaceuticals, Inc. | Tail variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
| US9278085B2 (en) * | 2006-02-22 | 2016-03-08 | Edison Pharmaceuticals, Inc. | Side-chain variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
| WO2007103585A2 (en) * | 2006-03-09 | 2007-09-13 | Synapse Biomedical, Inc. | Ventilator assist system and method to improve respiratory function |
| US20080097153A1 (en) * | 2006-08-24 | 2008-04-24 | Ignagni Anthony R | Method and apparatus for grasping an abdominal wall |
| US9079016B2 (en) * | 2007-02-05 | 2015-07-14 | Synapse Biomedical, Inc. | Removable intramuscular electrode |
| US9820671B2 (en) * | 2007-05-17 | 2017-11-21 | Synapse Biomedical, Inc. | Devices and methods for assessing motor point electromyogram as a biomarker |
| US8428726B2 (en) | 2007-10-30 | 2013-04-23 | Synapse Biomedical, Inc. | Device and method of neuromodulation to effect a functionally restorative adaption of the neuromuscular system |
| WO2009059033A1 (en) * | 2007-10-30 | 2009-05-07 | Synapse Biomedical, Inc. | Method of improving sleep disordered breathing |
| WO2009061744A2 (en) | 2007-11-06 | 2009-05-14 | Edison Pharmaceuticals, Inc. | 4- (p-quinonyl)-2-hydroxybutanamide derivatives for treatment of mitochondrial diseases |
| EA023618B1 (ru) * | 2008-01-08 | 2016-06-30 | Эдисон Фармасьютикалз, Инк. | Производные (гет)арил-п-хинона для лечения митохондриальных болезней |
| EP2262519A4 (en) * | 2008-03-05 | 2011-03-23 | Edison Pharmaceuticals Inc | TREATMENT OF HEARING AND BALANCING DISORDERS WITH REDOXACTIVE THERAPEUTICS |
| WO2009111576A2 (en) | 2008-03-05 | 2009-09-11 | Edison Pharmaceuticals, Inc. | 2-SUBSTITUTED-p-QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES |
| WO2009158348A1 (en) * | 2008-06-25 | 2009-12-30 | Edison Pharmaceuticals, Inc. | 2-heterocyclylaminoalkyl-(p-quinone) derivatives for treatment of oxidative stress diseases |
| EP2344142B1 (en) | 2008-09-10 | 2024-06-26 | PTC Therapeutics, Inc. | Treatment of pervasive developmental disorders with redox-active therapeutics |
| US8263094B2 (en) * | 2008-09-23 | 2012-09-11 | Eastman Chemical Company | Esters of 4,5-disubstituted-oxy-2-methyl-3,6-dioxo-cyclohexa-1,4-dienyl alkyl acids and preparation thereof |
| EP2362726B1 (en) * | 2008-10-14 | 2018-08-08 | Bioelectron Technology Corporation | Treatment of oxidative stress disorders including contrast nephropathy, radiation damage and disruptions in the function of red cells |
| CA2741767C (en) | 2008-10-28 | 2017-09-12 | Ptc Therapeutics, Inc. | Process for the production of alpha-tocotrienol and derivatives |
| PL2424495T3 (pl) | 2009-04-28 | 2018-06-29 | Bioelectron Technology Corporation | Leczenie dziedzicznej neuropatii nerwów wzrokowych lebera i dominującego zaniku nerwu wzrokowego chinonami tokotrienolu |
| DK2470168T3 (en) * | 2009-08-26 | 2018-05-07 | Bioelectron Tech Corp | PROCEDURES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCAM |
| AU2012249920B2 (en) | 2011-04-26 | 2017-06-15 | Biojiva Llc | Disorders implicating PUFA oxidation |
| AU2012249917B2 (en) | 2011-04-26 | 2017-06-15 | Biojiva Llc | Neurodegenerative disorders and muscle diseases implicating PUFAs |
| EP3689342A1 (en) | 2011-04-26 | 2020-08-05 | Retrotope, Inc. | Oxidative retinal diseases |
| AU2012249918B2 (en) | 2011-04-26 | 2017-06-15 | Biojiva Llc | Impaired energy processing disorders and mitochondrial deficiency |
| WO2012174286A1 (en) | 2011-06-14 | 2012-12-20 | Edison Pharmaceuticals, Inc. | Catechol derivatives for treatment of oxidative stress diseases |
| JP2014520894A (ja) | 2011-07-19 | 2014-08-25 | エジソン ファーマシューティカルズ, インコーポレイテッド | 非アルファトコトリエノールの存在下でのアルファトコトリエノールの選択的酸化のための方法 |
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| US9296712B2 (en) | 2013-03-15 | 2016-03-29 | Edison Pharmaceuticals, Inc. | Resorufin derivatives for treatment of oxidative stress disorders |
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| WO2015026708A2 (en) * | 2013-08-20 | 2015-02-26 | Wilson Robert B | Amelioration of the effects of friedriech's ataxia |
| CN106170206A (zh) | 2014-03-13 | 2016-11-30 | 乐巢拓普有限公司 | 视神经病变治疗和用稳定的多不饱和物质减少类固醇诱导的氧化应激 |
| AU2015364640B2 (en) | 2014-12-16 | 2020-08-13 | Ptc Therapeutics, Inc. | Polymorphic and amorphous forms of (R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide |
| EP3390377B1 (en) | 2015-12-16 | 2026-03-25 | PTC Therapeutics, Inc. | Improved methods for enriching alpha-tocotrienol from mixed tocol compositions |
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-
2006
- 2006-09-15 CA CA2622523A patent/CA2622523C/en active Active
- 2006-09-15 PT PT68147495T patent/PT1933821T/pt unknown
- 2006-09-15 WO PCT/US2006/036052 patent/WO2007035496A1/en not_active Ceased
- 2006-09-15 PL PL06814749T patent/PL1933821T3/pl unknown
- 2006-09-15 HU HUE06814749A patent/HUE052377T2/hu unknown
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- 2006-09-15 ES ES06814749T patent/ES2823728T3/es active Active
- 2006-09-15 LT LTEP06814749.5T patent/LT1933821T/lt unknown
- 2006-09-15 JP JP2008531360A patent/JP2009508867A/ja not_active Withdrawn
- 2006-09-15 EA EA200800819A patent/EA021818B1/ru not_active IP Right Cessation
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- 2006-09-15 SI SI200632388T patent/SI1933821T1/sl unknown
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2013
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2014
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2015
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2017
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Also Published As
| Publication number | Publication date |
|---|---|
| EA021818B1 (ru) | 2015-09-30 |
| PL1933821T3 (pl) | 2021-01-11 |
| JP2015078224A (ja) | 2015-04-23 |
| JP5999816B2 (ja) | 2016-09-28 |
| CA2622523C (en) | 2014-02-18 |
| DK1933821T3 (da) | 2020-10-26 |
| CA2622523A1 (en) | 2007-03-29 |
| ES2823728T3 (es) | 2021-05-10 |
| CY1123740T1 (el) | 2022-03-24 |
| EP1933821A1 (en) | 2008-06-25 |
| EP1933821B1 (en) | 2020-07-29 |
| HUE052377T2 (hu) | 2021-04-28 |
| JP2016040311A (ja) | 2016-03-24 |
| US7432305B2 (en) | 2008-10-07 |
| JP2009508867A (ja) | 2009-03-05 |
| JP2013155194A (ja) | 2013-08-15 |
| US20070072943A1 (en) | 2007-03-29 |
| EA200800819A1 (ru) | 2008-08-29 |
| PT1933821T (pt) | 2020-10-15 |
| JP2017193570A (ja) | 2017-10-26 |
| SI1933821T1 (sl) | 2020-11-30 |
| WO2007035496A1 (en) | 2007-03-29 |
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