LT3424955T - Anti-trop2 antikūno ir vaisto konjugato gamybos būdas - Google Patents

Anti-trop2 antikūno ir vaisto konjugato gamybos būdas

Info

Publication number
LT3424955T
LT3424955T LTEP18187671.5T LT18187671T LT3424955T LT 3424955 T LT3424955 T LT 3424955T LT 18187671 T LT18187671 T LT 18187671T LT 3424955 T LT3424955 T LT 3424955T
Authority
LT
Lithuania
Prior art keywords
producing
drug conjugate
trop2 antibody
trop2
antibody
Prior art date
Application number
LTEP18187671.5T
Other languages
English (en)
Inventor
Toshinori Agatsuma
Shu Takahashi
Jun Hasegawa
Daisuke Okajima
Hirofumi Hamada
Miki Yamaguchi
Original Assignee
Daiichi Sankyo Company, Limited
Sapporo Medical University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53477995&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT3424955(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Daiichi Sankyo Company, Limited, Sapporo Medical University filed Critical Daiichi Sankyo Company, Limited
Publication of LT3424955T publication Critical patent/LT3424955T/lt

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    • A61K47/6889Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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