LV12264B - Promoters of the genses glutamate deshydrogenase, beta-n-acetylhexosaminidase and gamma-actine, and their use in systems of expression, secretion and anti-sens in filamentary fungi - Google Patents

Promoters of the genses glutamate deshydrogenase, beta-n-acetylhexosaminidase and gamma-actine, and their use in systems of expression, secretion and anti-sens in filamentary fungi Download PDF

Info

Publication number: LV12264B
Authority: LV; Latvia
Prior art keywords: chrysogenum; gene; ala; vai; gly
Prior art date: 1997-03-05

Application number

LVP-98-268A

Other languages

English (en)

Latvian (lv)

Other versions

LV12264A (lv

Inventor

Jose Luis Barredo Fuente

Marta Rodriguez Saiz

Miguel Angel Moreno Valle

Alfonso J. Collados De La Vieja

Francisco SALTO MALDONADO

Bruno Diez Garcia

Original Assignee

Antibioticos, S.A.U.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-03-05

Filing date

1998-11-05

Publication date

1999-10-20

1998-11-05 Application filed by Antibioticos, S.A.U. filed Critical Antibioticos, S.A.U.

1999-04-20 Publication of LV12264A publication Critical patent/LV12264A/xx

1999-10-20 Publication of LV12264B publication Critical patent/LV12264B/en

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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
- C12N9/0016—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
- C12Y104/01—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with NAD+ or NADP+ as acceptor (1.4.1)
- C12Y104/01002—Glutamate dehydrogenase (1.4.1.2)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01052—Beta-N-acetylhexosaminidase (3.2.1.52)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Biomedical Technology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Medicinal Chemistry (AREA)
Mycology (AREA)
Virology (AREA)
Enzymes And Modification Thereof (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

LVP-98-268A 1997-03-05 1998-11-05 Promoters of the genses glutamate deshydrogenase, beta-n-acetylhexosaminidase and gamma-actine, and their use in systems of expression, secretion and anti-sens in filamentary fungi LV12264B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
ES009700482A ES2127697B1 (es)	1997-03-05	1997-03-05	Promotores de los genes glutamato deshidrogenasa, beta-n-acetilhexosaminidasa y gamma-actina y su utilizacion en sistemas de expresion, secrecion y antisentido de hongos filamentosos.
PCT/ES1998/000056 WO1998039459A1 (es)	1997-03-05	1998-03-05	PROMOTORES DE LOS GENES GLUTAMATO DESHIDROGENASA, β-N-ACETILHEXOSAMINIDASA η-ACTINA Y SU UTILIZACION EN SISTEMAS DE EXPRESION, SECRECION Y ANTISENTIDO DE HONGOS FILAMENTOSOS

Publications (2)

Publication Number	Publication Date
LV12264A LV12264A (lv)	1999-04-20
LV12264B true LV12264B (en)	1999-10-20

Family

ID=8298517

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LVP-98-268A LV12264B (en)	1997-03-05	1998-11-05	Promoters of the genses glutamate deshydrogenase, beta-n-acetylhexosaminidase and gamma-actine, and their use in systems of expression, secretion and anti-sens in filamentary fungi

Country Status (17)

Country	Link
US (2)	US6300095B1 (ja)
JP (1)	JP2000509613A (ja)
KR (1)	KR20000065202A (ja)
CN (1)	CN1219200A (ja)
AU (1)	AU6101198A (ja)
CA (1)	CA2253250A1 (ja)
CZ (1)	CZ353598A3 (ja)
EE (1)	EE9800381A (ja)
ES (3)	ES2127697B1 (ja)
HU (1)	HUP0000870A3 (ja)
IL (1)	IL126647A0 (ja)
LT (1)	LT4557B (ja)
LV (1)	LV12264B (ja)
PL (1)	PL329722A1 (ja)
SK (1)	SK149598A3 (ja)
WO (1)	WO1998039459A1 (ja)
ZA (1)	ZA981896B (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6610839B1 (en) *	1997-08-14	2003-08-26	Geron Corporation	Promoter for telomerase reverse transcriptase
US6777203B1 (en) *	1997-11-19	2004-08-17	Geron Corporation	Telomerase promoter driving expression of therapeutic gene sequences
ES2127697B1 (es) *	1997-03-05	2000-03-16	Antibioticos Sau	Promotores de los genes glutamato deshidrogenasa, beta-n-acetilhexosaminidasa y gamma-actina y su utilizacion en sistemas de expresion, secrecion y antisentido de hongos filamentosos.
US7378244B2 (en) *	1997-10-01	2008-05-27	Geron Corporation	Telomerase promoters sequences for screening telomerase modulators
ES2143408B1 (es) *	1998-04-02	2000-12-01	Urquima Sa	Promotor y construcciones para expresion de proteinas recombinantes en hongos filamentosos.
WO2000052176A1 (de) *	1999-03-03	2000-09-08	Cilian Ag	β-HEXOSAMINIDASE SOWIE DIESE KODIERENDE DNA-SEQUENZ AUS CILIATEN UND DEREN VERWENDUNG
US20090104165A1 (en) *	2004-09-22	2009-04-23	Bioworks, Inc.	Transgenic strains of trichoderma and their use in biocontrol
EP1801221A1 (en) *	2005-12-22	2007-06-27	Sandoz AG	Promoter sequences
CN102127546B (zh) *	2010-11-24	2012-10-24	山东农业大学	一种骨骼肌特异性actin启动子及其应用
CN116004892B (zh) *	2022-10-31	2025-04-29	中国热带农业科学院环境与植物保护研究所	一种香蕉灰纹病菌的pcr检测引物及检测方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8508800D0 (en) *	1985-04-04	1985-05-09	Glaxo Group Ltd	Microbiological process
FI864473L (fi) *	1985-11-20	1987-05-21	Panlabs Inc	Sammansatta yttryckskassetter foer fungaltransformering.
ES2127697B1 (es) *	1997-03-05	2000-03-16	Antibioticos Sau	Promotores de los genes glutamato deshidrogenasa, beta-n-acetilhexosaminidasa y gamma-actina y su utilizacion en sistemas de expresion, secrecion y antisentido de hongos filamentosos.

1997
- 1997-03-05 ES ES009700482A patent/ES2127697B1/es not_active Expired - Fee Related
1998
- 1998-03-05 US US09/171,337 patent/US6300095B1/en not_active Expired - Fee Related
- 1998-03-05 ZA ZA981896A patent/ZA981896B/xx unknown
- 1998-03-05 SK SK1495-98A patent/SK149598A3/sk unknown
- 1998-03-05 AU AU61011/98A patent/AU6101198A/en not_active Abandoned
- 1998-03-05 KR KR1019980708912A patent/KR20000065202A/ko not_active Withdrawn
- 1998-03-05 EE EE9800381A patent/EE9800381A/xx unknown
- 1998-03-05 PL PL98329722A patent/PL329722A1/xx unknown
- 1998-03-05 JP JP10538200A patent/JP2000509613A/ja not_active Ceased
- 1998-03-05 CZ CZ983535A patent/CZ353598A3/cs unknown
- 1998-03-05 IL IL12664798A patent/IL126647A0/xx unknown
- 1998-03-05 HU HU0000870A patent/HUP0000870A3/hu unknown
- 1998-03-05 CA CA002253250A patent/CA2253250A1/en not_active Abandoned
- 1998-03-05 WO PCT/ES1998/000056 patent/WO1998039459A1/es not_active Ceased
- 1998-03-05 CN CN98800237A patent/CN1219200A/zh active Pending
- 1998-09-03 ES ES009801858A patent/ES2149706B1/es not_active Expired - Fee Related
- 1998-09-03 ES ES009801859A patent/ES2149707B1/es not_active Expired - Fee Related
- 1998-10-23 LT LT98-152A patent/LT4557B/lt not_active IP Right Cessation
- 1998-11-05 LV LVP-98-268A patent/LV12264B/en unknown
2000
- 2000-08-02 US US09/631,022 patent/US6558921B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US6300095B1 (en)	2001-10-09
ES2149706B1 (es)	2001-05-16
KR20000065202A (ko)	2000-11-06
LT98152A (en)	1999-06-25
ES2149707A1 (es)	2000-11-01
LT4557B (lt)	1999-10-25
CZ353598A3 (cs)	1999-02-17
ES2149706A1 (es)	2000-11-01
US6558921B1 (en)	2003-05-06
EE9800381A (et)	1999-04-15
ZA981896B (en)	1998-09-14
CN1219200A (zh)	1999-06-09
PL329722A1 (en)	1999-04-12
LV12264A (lv)	1999-04-20
AU6101198A (en)	1998-09-22
HUP0000870A3 (en)	2001-09-28
IL126647A0 (en)	1999-08-17
WO1998039459A1 (es)	1998-09-11
ES2149707B1 (es)	2001-05-16
ES2127697A1 (es)	1999-04-16
SK149598A3 (en)	2000-03-13
ES2127697B1 (es)	2000-03-16
HUP0000870A2 (en)	2000-07-28
CA2253250A1 (en)	1998-09-11
JP2000509613A (ja)	2000-08-02

Publication	Publication Date	Title
Kimura et al.	1994	Cloning of the blasticidin S deaminase gene (BSD) from Aspergillus terreus and its use as a selectable marker for Schizosaccharomyces pombe and Pyricularia oryzae
EP0859849B1 (en)	2006-07-26	POLYPEPTIDES AND POLYNUCLEOTIDES RELATING TO THE ALPHA- and BETA-SUBUNITS OF GLUTAMATE DEHYDROGENASES AND METHODS OF USE
US6063614A (en)	2000-05-16	Transformed fungal strains free of selection marker
ES2537649T3 (es)	2015-06-10	Método para producir selectivamente plantas estériles masculinas o femeninas
Suzuki et al.	1991	Soybean nodule-specific uricase (Nodulin-35) is expressed and assembled into a functional tetrameric holoenzyme in Escherichia coli
WO1995004148A1 (en)	1995-02-09	Process for the efficient production of 7-adca via 2-(carboxyethylthio)acetyl-7-adca and 3-(carboxymethylthio)propionyl-7-adca
US6300095B1 (en)	2001-10-09	Promoters of the genes glutamate dehydrogenase β-N-acetylhexosaminidase and γ-actin and their use in filamentous fungi expression, secretion and antisense systems
US5795733A (en)	1998-08-18	Process for the efficient production of 7-ADCA via 3-(carboxyethylthio) propionyl-7-ADCA
EP0889134A1 (en)	1999-01-07	$g(b)-FRUCTOFURANOSIDASE AND ITS GENE, METHOD OF ISOLATING $g(b)-FRUCTOFURANOSIDASE GENE, SYSTEM FOR PRODUCING $g(b)-FRUCTOFURANOSIDASE, AND $g(b)-FRUCTOFURANOSIDASE VARIANT
Taylor et al.	1987	Molecular characterization of the cell cycle-regulated thymidylate synthase gene of Saccharomyces cerevisiae.
Saigal et al.	1991	Molecular cloning of the mitochondrial aldehyde dehydrogenase gene of Saccharomyces cerevisiae by genetic complementation
Singer et al.	1989	Cloning, purification, and properties of Candida albicans thymidylate synthase
US5108918A (en)	1992-04-28	Method for identifying and using biosynthetic genes for enhanced production of secondary metabolites
JPH04234994A (ja)	1992-08-24	７―アミノセフェム化合物またはその塩類の製造法
Kim et al.	1995	Control of de novo purine biosynthesis genes in ureide‐producing legumes: induction of glutamine phosphoribosylpyrophosphate amidotransferase gene and characterization of its cDNA from soybean and Vigna
US6051431A (en)	2000-04-18	Selection marker gene free recombinant strains: a method for obtaining them and the use of these strains
US5516679A (en)	1996-05-14	Penicillin V amidohydrolase gene from Fusarium oxysporum
Chin et al.	1994	Isolation, sequencing and expreauion of the gene encoding hypoxanthine-guanine-xanthine phosphoribosyltransferase of Tritrichomonas foetus
CA2045838A1 (en)	1992-01-31	Cloning and overexpression of glucose-6-phosphate dehydrogenase from leuconostoc dextranicus
US7485771B2 (en)	2009-02-03	Polypeptides and polynucleotides relating to the α- and β-subunits of glutamate dehydrogenases and methods of use
Szabo et al.	1989	The nucleotide sequence of POX18, a gene encoding a small oleate-inducible peroxisomal protein from Candida tropicalis
US5457037A (en)	1995-10-10	Cloning of the gene coding the isoamylase enzyme and its use in the production of said enzyme
EP1383886B1 (en)	2008-07-30	D-hydantoinase from ochrobactrum anthropi
MXPA98009198A (en)	2000-05-01	PROMOTERS OF THE GENES GLUTAMATE DESHYDROGENASE,&bgr;-N-ACETYLHEXOSAMINIDASE AND$b(g)-ACTINE, AND THEIR USE IN SYSTEMS OF EXPRESSION, SECRETION AND ANTI-SENS IN FILAMENTARY FUNGI
US6913905B1 (en)	2005-07-05	Regulatory sequences functioning in filamentous fungi