MA28359A1 - Antagonistes du recepteur a l'hydroisoindoline tachykinine - Google Patents

Antagonistes du recepteur a l'hydroisoindoline tachykinine

Info

Publication number: MA28359A1
Authority: MA; Morocco
Prior art keywords: antagonists; tachykinin receptor; hydroisoindoline; hydroisoindoline tachykinin; receptor
Prior art date: 2004-01-27

Application number

MA29265A

Other languages

English (en)

Inventor

Jaime Lynn Bunda

Robert J Devita

Jinlong Jiang

Sander G Mills

Original Assignee

Merck Sharp & Dohme

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-01-27

Filing date

2006-08-11

Publication date

2006-12-01

2006-08-11 Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme

2006-12-01 Publication of MA28359A1 publication Critical patent/MA28359A1/fr

Links

102000007124 Tachykinin Receptors Human genes 0.000 title 1
108010072901 Tachykinin Receptors Proteins 0.000 title 1
239000005557 antagonist Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/4035—Isoindoles, e.g. phthalimide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Epidemiology (AREA)
Pain & Pain Management (AREA)
Urology & Nephrology (AREA)
Psychiatry (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

MA29265A 2004-01-27 2006-08-11 Antagonistes du recepteur a l'hydroisoindoline tachykinine MA28359A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US53991304P	2004-01-27	2004-01-27
US56122704P	2004-04-09	2004-04-09

Publications (1)

Publication Number	Publication Date
MA28359A1 true MA28359A1 (fr)	2006-12-01

Family

ID=34830494

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA29265A MA28359A1 (fr)	2004-01-27	2006-08-11	Antagonistes du recepteur a l'hydroisoindoline tachykinine

Country Status (30)

Country	Link
US (3)	US7645790B2 (fr)
EP (1)	EP1711465B1 (fr)
JP (1)	JP3987100B2 (fr)
KR (1)	KR20060127927A (fr)
AR (1)	AR047439A1 (fr)
AT (1)	ATE382034T1 (fr)
AU (1)	AU2005207934B2 (fr)
BR (1)	BRPI0507050A (fr)
CA (1)	CA2554550C (fr)
CO (1)	CO5700771A2 (fr)
CR (1)	CR8522A (fr)
CY (1)	CY1107167T1 (fr)
DE (1)	DE602005004011T2 (fr)
DK (1)	DK1711465T3 (fr)
EA (1)	EA010598B1 (fr)
EC (1)	ECSP066716A (fr)
ES (1)	ES2297687T3 (fr)
GE (1)	GEP20094691B (fr)
HR (1)	HRP20080100T3 (fr)
IL (1)	IL176879A0 (fr)
MA (1)	MA28359A1 (fr)
NI (1)	NI200600164A (fr)
NO (1)	NO339041B1 (fr)
NZ (1)	NZ548415A (fr)
PE (1)	PE20050687A1 (fr)
PL (1)	PL1711465T3 (fr)
PT (1)	PT1711465E (fr)
TW (1)	TWI341198B (fr)
UA (1)	UA84192C2 (fr)
WO (1)	WO2005073191A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR047439A1 (es)	2004-01-27	2006-01-18	Merck & Co Inc	Antagonistas del receptor hidroisoindolina taquiquinina
US7652058B2 (en)	2004-12-14	2010-01-26	Merck Sharp & Dohme Corp.	Octahydropyrano[3,4-C]pyrrole tachykinin receptor antagonists
CA2611550A1 (fr) *	2005-06-27	2007-01-04	Merck & Co., Inc.	Antagonistes des recepteurs de tachykinine hydro-iso-indolique
WO2007008564A1 (fr)	2005-07-11	2007-01-18	Merck & Co., Inc.	Procede de fabrication d'antagonistes des recepteurs de l'hydroisoindoline tachykinine
ATE511842T1 (de)	2005-10-04	2011-06-15	Merck Sharp & Dohme	Kombinationstherapie zur behandlung von erhöhter miktionsfrequenz, akutem harndrang und inkontinenz
WO2007075528A2 (fr) *	2005-12-22	2007-07-05	Merck & Co., Inc.	Antagonistes de recepteur d’octahydropyrano[3,4-c]pyrrole-tachykinine
EP1978965A2 (fr) *	2006-01-24	2008-10-15	Merck & Co., Inc.	Hexahydro-3h-pyrrolizin-3-ones utiles en tant qu'antagonistes du récepteur de la tachykinine
US20100209496A1 (en) *	2006-09-06	2010-08-19	Eleni Dokou	Liquid and semi-solid pharmaceutical formulations for oral administration of a substituted amide
US20090270477A1 (en) *	2006-11-02	2009-10-29	Kuethe Jeffrey T	Polymorphs of a hydroisoindoline tachykinin receptor antagonist
AU2008233232A1 (en) *	2007-03-29	2008-10-09	Merck Sharp & Dohme Corp.	Combination therapy for the treatment-of lower urinary tract symptoms
US8124633B2 (en)	2007-04-10	2012-02-28	Merck Sharp & Dohme Corp.	Hydroxymethyl ether hydroisoindoline tachykinin receptor antagonists
WO2011137054A1 (fr)	2010-04-30	2011-11-03	Merck Sharp & Dohme Corp.	Nouveaux agonistes du récepteur bêta 3 adrénergique
US8627816B2 (en)	2011-02-28	2014-01-14	Intelliject, Inc.	Medicament delivery device for administration of opioid antagonists including formulations for naloxone
WO2013004766A1 (fr)	2011-07-04	2013-01-10	Ferrari Giulio	Antagonistes des récepteurs nk-1 pour traiter une néovascularisation cornéenne
CA2915474A1 (fr) *	2013-06-24	2014-12-31	Tigercat Pharma, Inc.	Utilisation de serlopitant, antagoniste du recepteur nk -1, dans le traitement du prurit
US9198898B2 (en)	2013-06-24	2015-12-01	Tigercat Pharma, Inc.	Use of NK-1 receptor antagonists in pruritus
US8906951B1 (en)	2013-06-24	2014-12-09	Tigercat Pharma, Inc.	Use of NK-1 receptor antagonists in pruritus
IL312486B2 (en)	2017-04-10	2025-05-01	Chase Therapeutics Corp	NK1 antagonist combination and method for treating synucleinopathies
CA3104811C (fr)	2017-06-30	2024-05-28	Chase Therapeutics Corporation	Composition comprenant du pramipexole et des antagonistes nk1 pour traiter la depression
US20210015834A1 (en)	2018-02-26	2021-01-21	Ospedale San Raffaele S.R.L.	Nk-1 antagonists for use in the treatment of ocular pain
WO2021180885A1 (fr)	2020-03-11	2021-09-16	Ospedale San Raffaele S.R.L.	Traitement d'une déficience en cellules souches
CA3173697A1 (fr)	2020-04-03	2021-10-07	Mike TROWER	Antagoniste du recepteur de nk-1 pour le traitement d'une maladie choisie parmi une septicemie, un choc septique, un syndrome de detresse respiratoire aigue (ards) ou un syndrome de dysfonctionnement des organes multiples (mods
CA3177477A1 (fr)	2020-06-02	2021-12-09	Nerre Therapeutics Limited	Antagonistes du recepteur de la neurokinine (nk)-1 destines a etre utilises dans le traitement d'etats de fibrose pulmonaire favorises par une lesion mecanique des poumons

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5650142A (en) *	1995-09-27	1997-07-22	Church & Dwight Co., Inc.	Bicarbonate-containing deodorant cosmetic stick compositions
AU722883B2 (en) *	1995-10-18	2000-08-10	Merck & Co., Inc.	Cyclopentyl tachykinin receptor antagonists
AU2004277932B2 (en)	2003-09-30	2009-07-16	Merck & Co., Inc.	Phenyl pyrrolidine ether tachykinin receptor antagonists
AR047439A1 (es)	2004-01-27	2006-01-18	Merck & Co Inc	Antagonistas del receptor hidroisoindolina taquiquinina

2005
- 2005-01-20 AR ARP050100203A patent/AR047439A1/es active IP Right Grant
- 2005-01-20 TW TW094101721A patent/TWI341198B/zh not_active IP Right Cessation
- 2005-01-24 PE PE2005000090A patent/PE20050687A1/es not_active Application Discontinuation
- 2005-01-26 DK DK05726323T patent/DK1711465T3/da active
- 2005-01-26 EP EP05726323A patent/EP1711465B1/fr not_active Expired - Lifetime
- 2005-01-26 EA EA200601378A patent/EA010598B1/ru not_active IP Right Cessation
- 2005-01-26 GE GEAP20059594A patent/GEP20094691B/en unknown
- 2005-01-26 HR HR20080100T patent/HRP20080100T3/xx unknown
- 2005-01-26 UA UAA200609315A patent/UA84192C2/ru unknown
- 2005-01-26 DE DE602005004011T patent/DE602005004011T2/de not_active Expired - Lifetime
- 2005-01-26 PT PT05726323T patent/PT1711465E/pt unknown
- 2005-01-26 US US10/586,727 patent/US7645790B2/en active Active
- 2005-01-26 AT AT05726323T patent/ATE382034T1/de active
- 2005-01-26 WO PCT/US2005/002149 patent/WO2005073191A1/fr not_active Ceased
- 2005-01-26 BR BRPI0507050-3A patent/BRPI0507050A/pt not_active IP Right Cessation
- 2005-01-26 ES ES05726323T patent/ES2297687T3/es not_active Expired - Lifetime
- 2005-01-26 AU AU2005207934A patent/AU2005207934B2/en not_active Ceased
- 2005-01-26 NZ NZ548415A patent/NZ548415A/en not_active IP Right Cessation
- 2005-01-26 PL PL05726323T patent/PL1711465T3/pl unknown
- 2005-01-26 JP JP2006551356A patent/JP3987100B2/ja not_active Expired - Fee Related
- 2005-01-26 CA CA2554550A patent/CA2554550C/fr not_active Expired - Fee Related
- 2005-01-26 KR KR1020067015184A patent/KR20060127927A/ko not_active Ceased
- 2005-01-26 US US11/043,213 patent/US7217731B2/en not_active Expired - Lifetime
2006
- 2006-07-16 IL IL176879A patent/IL176879A0/en unknown
- 2006-07-19 CR CR8522A patent/CR8522A/es not_active Application Discontinuation
- 2006-07-21 EC EC2006006716A patent/ECSP066716A/es unknown
- 2006-07-26 NI NI200600164A patent/NI200600164A/es unknown
- 2006-07-27 CO CO06073837A patent/CO5700771A2/es active IP Right Grant
- 2006-08-11 MA MA29265A patent/MA28359A1/fr unknown
- 2006-08-25 NO NO20063810A patent/NO339041B1/no not_active IP Right Cessation
2007
- 2007-03-06 US US11/714,352 patent/US7345083B2/en not_active Expired - Lifetime
2008
- 2008-01-31 CY CY20081100113T patent/CY1107167T1/el unknown

Also Published As

Publication number	Publication date
WO2005073191A1 (fr)	2005-08-11
KR20060127927A (ko)	2006-12-13
CR8522A (es)	2007-06-06
CY1107167T1 (el)	2012-10-24
PE20050687A1 (es)	2005-09-27
CA2554550A1 (fr)	2005-08-11
AU2005207934A1 (en)	2005-08-11
IL176879A0 (en)	2006-10-31
NI200600164A (es)	2007-05-29
CO5700771A2 (es)	2006-11-30
AU2005207934B2 (en)	2010-11-25
BRPI0507050A (pt)	2007-06-12
NZ548415A (en)	2009-11-27
EA010598B1 (ru)	2008-10-30
GEP20094691B (en)	2009-05-25
CA2554550C (fr)	2011-05-03
ECSP066716A (es)	2006-10-31
TW200534850A (en)	2005-11-01
NO20063810L (no)	2006-10-26
PT1711465E (pt)	2008-02-25
JP3987100B2 (ja)	2007-10-03
US20050165083A1 (en)	2005-07-28
DE602005004011D1 (de)	2008-02-07
DE602005004011T2 (de)	2008-12-11
EP1711465B1 (fr)	2007-12-26
ES2297687T3 (es)	2008-05-01
US7645790B2 (en)	2010-01-12
ATE382034T1 (de)	2008-01-15
JP2007519728A (ja)	2007-07-19
HK1100937A1 (zh)	2007-10-05
HRP20080100T3 (en)	2008-04-30
TWI341198B (en)	2011-05-01
AR047439A1 (es)	2006-01-18
US20080280966A1 (en)	2008-11-13
US20070161695A1 (en)	2007-07-12
DK1711465T3 (da)	2008-03-31
EP1711465A1 (fr)	2006-10-18
US7217731B2 (en)	2007-05-15
NO339041B1 (no)	2016-11-07
UA84192C2 (en)	2008-09-25
US7345083B2 (en)	2008-03-18
PL1711465T3 (pl)	2008-05-30
EA200601378A1 (ru)	2007-02-27

Publication	Publication Date	Title
MA28359A1 (fr)	2006-12-01	Antagonistes du recepteur a l'hydroisoindoline tachykinine
EP1725238A4 (fr)	2009-04-01	Antagonistes du recepteur muscarinique a l'acetylcholine m 3
NO20051871D0 (no)	2005-04-18	Opioid reseptorantagonister
EP2049110A4 (fr)	2011-08-10	Diazépans pontés antagonistes du récepteur de l'oréxine
ATE413400T1 (de)	2008-11-15	Cgrp-rezeptorantagonisten
DK1682142T3 (da)	2012-10-15	M3-muscarin-acetylcholin-receptor-antagonister
MA29034B1 (fr)	2007-11-01	Posologie d'un agoniste du recepteur s1p
PT2570128T (pt)	2016-10-07	Antagonistas do receptor muscarínico de acetilcolina
EP1765805A4 (fr)	2009-08-26	Antagonistes des recepteurs du cgrp
EP1641781A4 (fr)	2010-06-23	Antagonistes du recepteur cgrp de benzodiazepine
DK1501809T3 (da)	2008-05-13	Trizolderivater som tachykininreceptorantagonister
EP1444251A4 (fr)	2005-12-21	Peptides cycliques comme antagonistes du recepteur couple a la proteine g
EP1871752A4 (fr)	2009-09-30	Antagonistes du récepteur de l' orexine de type amidopropoxyphényle
EP1814550A4 (fr)	2009-10-21	Antagonistes du recepteur 1 de n-sulfonylpiperidine cannabinoide
EP1846455A4 (fr)	2010-02-17	Anticorps de recepteur de l'oncostatine m
EP1827421A4 (fr)	2011-03-30	Modulateurs du recepteur de l'oestrogene
IS8522A (is)	2006-06-26	Ný M3 múskarínasetýlkólínviðtakamótlyf
IS8515A (is)	2006-06-19	Ný M3 múskarínasetýlkólínviðtakamótlyf
EP1799672A4 (fr)	2011-01-19	Antagonistes du recepteur de cgrp
EP1813875A4 (fr)	2011-03-02	Unite interieure d'un climatiseur
MA28363A1 (fr)	2006-12-01	Antagonistes des recepteurs muscariniques de l'acetylcholine
EP1819342A4 (fr)	2008-12-17	Antagonistes de récepteurs de tachykinine de type quinoline
EP2076285A4 (fr)	2010-06-30	Antagonistes d'anticorps du récepteur 1 de l'interleukine-13
EP1819677A4 (fr)	2009-03-11	Antagonistes du recepteur de tachykinine de 8-phenyl-5,6,7,8-hydroquinoline
EP1951228A4 (fr)	2010-11-03	Antagonistes du recepteur cgrp biclyclique de spirohydantoine