MA29633B1 - Sels metalliques du 2'-(1h-tetrazol-5-yl)-1, 1'-biphenyl-4-carboxaldehyde - Google Patents
Sels metalliques du 2'-(1h-tetrazol-5-yl)-1, 1'-biphenyl-4-carboxaldehydeInfo
- Publication number
- MA29633B1 MA29633B1 MA30579A MA30579A MA29633B1 MA 29633 B1 MA29633 B1 MA 29633B1 MA 30579 A MA30579 A MA 30579A MA 30579 A MA30579 A MA 30579A MA 29633 B1 MA29633 B1 MA 29633B1
- Authority
- MA
- Morocco
- Prior art keywords
- carboxaldehyde
- tetrazol
- biphenyl
- metal salts
- new
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 2
- HQBRKMUDLIZVAS-UHFFFAOYSA-N 4-[2-(2h-tetrazol-5-yl)phenyl]benzaldehyde Chemical compound C1=CC(C=O)=CC=C1C1=CC=CC=C1C1=NN=NN1 HQBRKMUDLIZVAS-UHFFFAOYSA-N 0.000 title 1
- 239000002184 metal Substances 0.000 title 1
- 238000000034 method Methods 0.000 abstract 5
- 239000000543 intermediate Substances 0.000 abstract 2
- 239000004072 C09CA03 - Valsartan Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- -1 cleavage Substances 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- SJSNUMAYCRRIOM-QFIPXVFZSA-N valsartan Chemical compound C1=CC(CN(C(=O)CCCC)[C@@H](C(C)C)C(O)=O)=CC=C1C1=CC=CC=C1C1=NN=N[N]1 SJSNUMAYCRRIOM-QFIPXVFZSA-N 0.000 abstract 1
- 229960004699 valsartan Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Catalysts (AREA)
Abstract
Sels métalliques de 2'-(1H-tétrazol-5-yl)-1,1'-biphényl-4-carboxaldéhyde L'invention concerne une méthode ou un procédé de fabrication d'agents de réduction de la pression sanguine, tels que le valsartan, de nouveaux intermédiaires, ainsi que les étapes de procédé de ladite synthèse. La méthode ou le procédé est conduit(e) par l'intermédiaire des nouveaux sels intermédiaires de formule (IA) : ou d'un tautomère de ceux-ci, où [Kat]n+ est un cation et n vaut 1, 2, 3, 4, 5 ou 6.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0514206.2A GB0514206D0 (en) | 2005-07-11 | 2005-07-11 | Organic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA29633B1 true MA29633B1 (fr) | 2008-07-01 |
Family
ID=34897057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA30579A MA29633B1 (fr) | 2005-07-11 | 2008-01-16 | Sels metalliques du 2'-(1h-tetrazol-5-yl)-1, 1'-biphenyl-4-carboxaldehyde |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US7728024B2 (fr) |
| EP (1) | EP1912956B1 (fr) |
| JP (1) | JP2009500434A (fr) |
| KR (1) | KR20080030609A (fr) |
| CN (2) | CN101208313A (fr) |
| AR (1) | AR054823A1 (fr) |
| AT (1) | ATE504577T1 (fr) |
| AU (1) | AU2006268906B2 (fr) |
| BR (1) | BRPI0613129A2 (fr) |
| CA (1) | CA2614718A1 (fr) |
| DE (1) | DE602006021187D1 (fr) |
| EC (1) | ECSP088090A (fr) |
| ES (1) | ES2363439T3 (fr) |
| GB (1) | GB0514206D0 (fr) |
| GT (1) | GT200600303A (fr) |
| IL (1) | IL188190A0 (fr) |
| MA (1) | MA29633B1 (fr) |
| MX (1) | MX2008000465A (fr) |
| MY (1) | MY143947A (fr) |
| NO (1) | NO20080742L (fr) |
| NZ (1) | NZ564548A (fr) |
| PE (1) | PE20070248A1 (fr) |
| PL (1) | PL1912956T3 (fr) |
| PT (1) | PT1912956E (fr) |
| RU (1) | RU2435761C2 (fr) |
| SA (1) | SA06270220B1 (fr) |
| TN (1) | TNSN08005A1 (fr) |
| TW (1) | TW200745065A (fr) |
| WO (1) | WO2007006531A1 (fr) |
| ZA (1) | ZA200711023B (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008004110A2 (fr) | 2006-07-03 | 2008-01-10 | Aurobindo Pharma Limited | Procédé amélioré de préparation d'un antagoniste de l'angiotensine ii |
| US8492577B2 (en) | 2008-04-07 | 2013-07-23 | Hetero Research Foundation | Process for preparation of valsartan intermediate |
| CN103012301B (zh) * | 2013-01-05 | 2015-06-17 | 江苏施美康药业股份有限公司 | 缬沙坦甲酯碱金属盐及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0550313A1 (fr) * | 1991-12-30 | 1993-07-07 | Synthelabo | Nouveaux dérivés de 2-(tétrazol-5-yl)-(1,1'-biphényle), leur préparation et leur utilisation comme intermédiaires de synthèse |
| JP4568400B2 (ja) * | 2000-03-24 | 2010-10-27 | 株式会社日本ファインケム | 水和ヒドラジンとジシアンを原料とする５，５’−ビ−１ｈ−テトラゾールジアンモニウム塩の製造方法 |
| GB0222056D0 (en) | 2002-09-23 | 2002-10-30 | Novartis Ag | Process for the manufacture of organic compounds |
| GB0316546D0 (en) * | 2003-07-15 | 2003-08-20 | Novartis Ag | Process for the manufacture of organic compounds |
| JP2007501770A (ja) * | 2003-08-08 | 2007-02-01 | ディフアルマ ソシエタ ペル アチオニ | フェニルテトラゾール誘導体の製造方法 |
| ITMI20032267A1 (it) | 2003-11-21 | 2005-05-22 | Dinamite Dipharma S P A In Forma A Bbreviata Diph | Procdimento per la preparzione di valsartan e suoi intermedi |
-
2005
- 2005-07-11 GB GBGB0514206.2A patent/GB0514206D0/en not_active Ceased
-
2006
- 2006-07-06 MY MYPI20063226A patent/MY143947A/en unknown
- 2006-07-07 PE PE2006000810A patent/PE20070248A1/es not_active Application Discontinuation
- 2006-07-07 AR ARP060102936A patent/AR054823A1/es not_active Application Discontinuation
- 2006-07-10 PT PT06754707T patent/PT1912956E/pt unknown
- 2006-07-10 PL PL06754707T patent/PL1912956T3/pl unknown
- 2006-07-10 TW TW095125125A patent/TW200745065A/zh unknown
- 2006-07-10 ES ES06754707T patent/ES2363439T3/es active Active
- 2006-07-10 GT GT200600303A patent/GT200600303A/es unknown
- 2006-07-10 RU RU2008104526/04A patent/RU2435761C2/ru not_active IP Right Cessation
- 2006-07-10 AU AU2006268906A patent/AU2006268906B2/en not_active Ceased
- 2006-07-10 KR KR1020087000723A patent/KR20080030609A/ko not_active Ceased
- 2006-07-10 SA SA06270220A patent/SA06270220B1/ar unknown
- 2006-07-10 BR BRPI0613129-8A patent/BRPI0613129A2/pt not_active IP Right Cessation
- 2006-07-10 CA CA002614718A patent/CA2614718A1/fr not_active Abandoned
- 2006-07-10 US US11/995,240 patent/US7728024B2/en not_active Expired - Fee Related
- 2006-07-10 EP EP06754707A patent/EP1912956B1/fr active Active
- 2006-07-10 MX MX2008000465A patent/MX2008000465A/es active IP Right Grant
- 2006-07-10 AT AT06754707T patent/ATE504577T1/de active
- 2006-07-10 CN CNA2006800230702A patent/CN101208313A/zh active Pending
- 2006-07-10 NZ NZ564548A patent/NZ564548A/en not_active IP Right Cessation
- 2006-07-10 JP JP2008520770A patent/JP2009500434A/ja active Pending
- 2006-07-10 CN CNA2009100032514A patent/CN101468972A/zh active Pending
- 2006-07-10 DE DE602006021187T patent/DE602006021187D1/de active Active
- 2006-07-10 WO PCT/EP2006/006730 patent/WO2007006531A1/fr not_active Ceased
-
2007
- 2007-12-17 IL IL188190A patent/IL188190A0/en unknown
- 2007-12-19 ZA ZA200711023A patent/ZA200711023B/xx unknown
-
2008
- 2008-01-10 EC EC2008008090A patent/ECSP088090A/es unknown
- 2008-01-10 TN TNP2008000005A patent/TNSN08005A1/en unknown
- 2008-01-16 MA MA30579A patent/MA29633B1/fr unknown
- 2008-02-11 NO NO20080742A patent/NO20080742L/no not_active Application Discontinuation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA33540B1 (fr) | Dérivés de la pyridine et de la pyrazine en tant que modulateurs de la protéine kinase | |
| MA31084B1 (fr) | Derives de piperidine agonistes de gpcr | |
| MA29772B1 (fr) | Benzimidazoles substitues et procedes de preparation | |
| MA29620B1 (fr) | Nouveau derive de 1,4-benzothiazepine-1,1-dioxyde presentant des proprietes ameliorees, procede pour sa preparation, medicaments contenant ce compose, et son utilisation | |
| TW200740760A (en) | Malonamide derivatives | |
| TN2009000544A1 (fr) | Derives de benzimidazole | |
| MA28687B1 (fr) | Composes organiques | |
| MA28077A1 (fr) | Derives d'isoquinilone 1,4-disubstitues en tant qu'inhibiteurs de raf-kinase utiles pour le traitement de maladies proliferantes | |
| MA29539B1 (fr) | Procedes de production de derives phenoliques 4-biphenylylazetidin -2-one | |
| MA30722B1 (fr) | Utilisation de derives de l'adenosine en tant qu'agonistes du recepteurs a2a | |
| MA30991B1 (fr) | Utilisation de dérivés du benzamide comme agonistes des récepteurs ep4 | |
| MA30075B1 (fr) | Derives de pyrimidine pour le traitement d'une croissance cellulaire anormale | |
| MA29688B1 (fr) | Formulation d'un inhibiteur de l'agregation plaquettaire thienopyridine | |
| EA201101005A1 (ru) | Фунгицидная композиция | |
| MA31989B1 (fr) | Dérivés d'indolinone et procédés pour leur fabrication | |
| MA32903B1 (fr) | Inhibiteurs de proteine-kinases | |
| MA32790B1 (fr) | Nouvelle composition a base d'acide gamma-hydroxybutyrique | |
| MA34965B1 (fr) | Procédé de production de dérivé de dihydrobenzofurane optiquement actif | |
| WO2007091009A3 (fr) | Préparation de delmopinol | |
| MA29170B1 (fr) | Derives puriniques agissant comme des agonistes du recepteur a2a | |
| MA29633B1 (fr) | Sels metalliques du 2'-(1h-tetrazol-5-yl)-1, 1'-biphenyl-4-carboxaldehyde | |
| MA31910B1 (fr) | Antagonistes des recepteurs non steroidiens des mineralocorticoides derives de la 6h-dibenzo[b,e]oxepine | |
| MA30693B1 (fr) | Derives de la purine utilises en tant qu'agonistes de l'a2a | |
| MA30704B1 (fr) | Compositions therapeutiques | |
| MA31926B1 (fr) | Procédé pour la préparation de 1-(2h)-isoquinoléinones 6-substituées |