MA33214B1 - Compose pyrazole - Google Patents
Compose pyrazoleInfo
- Publication number
- MA33214B1 MA33214B1 MA34275A MA34275A MA33214B1 MA 33214 B1 MA33214 B1 MA 33214B1 MA 34275 A MA34275 A MA 34275A MA 34275 A MA34275 A MA 34275A MA 33214 B1 MA33214 B1 MA 33214B1
- Authority
- MA
- Morocco
- Prior art keywords
- atom
- hydrogen atom
- substituted
- halogen
- substituent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
LA PRÉSENTE INVENTION CONCERNE UN COMPOSÉ AYANT UNE EXCELLENTE ACTIVITÉ INHIBITRICE SUR LA SÉCRÉTION D'UN ACIDE ET PRÉSENTANT ENTRE AUTRES UNE ACTIVITÉ ANTITUMORALE. LA PRÉSENTE INVENTION CONCERNE SPÉCIFIQUEMENT UN COMPOSÉ REPRÉSENTÉ PAR LA FORMULE (1) [DANS LAQUELLE R1 REPRÉSENTE UN SUBSTITUANT; R2 REPRÉSENTE UN ATOME D'HYDROGÈNE, UN GROUPE ALKYLE EN C1 À C6 QUI PEUT ÊTRE SUBSTITUÉ PAR UN ATOME D'HALOGÈNE, OU UN GROUPE CYANO; ET R3 REPRÉSENTE UN ATOME D'HYDROGÈNE, UN ATOME D'HALOGÈNE, UN GROUPE CYANO, UN GROUPE ALKYLE EN C1 À C6 QUI PEUT ÊTRE SUBSTITUÉ PAR UN ATOME D'HALOGÈNE, UN GROUPE ALCOXY EN C1 À C6 QUI PEUT ÊTRE SUBSTITUÉ PAR UN ATOME D'HALOGÈNE; L'UN DES R2 ET R3 REPRÉSENTANT UN ATOME D'HYDROGÈNE ET L'AUTRE REPRÉSENTANT UN SUBSTITUANT AUTRE QU'UN ATOME D'HYDROGÈNE] OU UN SEL DE CELUI-CI.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009077078 | 2009-03-26 | ||
| PCT/JP2010/055257 WO2010110378A1 (fr) | 2009-03-26 | 2010-03-25 | Composé pyrazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA33214B1 true MA33214B1 (fr) | 2012-04-02 |
Family
ID=42781069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA34275A MA33214B1 (fr) | 2009-03-26 | 2010-03-25 | Compose pyrazole |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US8895588B2 (fr) |
| EP (1) | EP2412713B1 (fr) |
| JP (1) | JP5552481B2 (fr) |
| KR (1) | KR101656906B1 (fr) |
| CN (1) | CN102448953B (fr) |
| AU (1) | AU2010228220B2 (fr) |
| BR (1) | BRPI1009090A2 (fr) |
| CA (1) | CA2756086A1 (fr) |
| CL (1) | CL2011002351A1 (fr) |
| CO (1) | CO6460700A2 (fr) |
| CR (1) | CR20110533A (fr) |
| DO (1) | DOP2011000296A (fr) |
| EA (1) | EA019853B1 (fr) |
| EC (1) | ECSP11011419A (fr) |
| GE (1) | GEP20156222B (fr) |
| IL (1) | IL215235A (fr) |
| MA (1) | MA33214B1 (fr) |
| MX (1) | MX2011009943A (fr) |
| NZ (1) | NZ595890A (fr) |
| PE (1) | PE20120618A1 (fr) |
| SG (1) | SG174476A1 (fr) |
| TN (1) | TN2011000474A1 (fr) |
| UA (1) | UA107457C2 (fr) |
| WO (1) | WO2010110378A1 (fr) |
| ZA (1) | ZA201107435B (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR091567A1 (es) | 2012-06-27 | 2015-02-11 | Takeda Pharmaceutical | Preparacion liquida, metodo, kit de inyeccion |
| TWI732158B (zh) | 2012-09-27 | 2021-07-01 | 美商雅瑞塔那醫療公司 | 使用食慾喪失控制化合物之組合物及方法 |
| ES2902795T3 (es) | 2015-01-28 | 2022-03-29 | Elanco Animal Health Incorporated | Composición para uso crónico como compuesto para aumentar de peso |
| CN105067814A (zh) * | 2015-07-24 | 2015-11-18 | 中国科学院成都生物研究所 | 解旋酶水解atp活性测定方法 |
| MX2022016515A (es) * | 2020-06-17 | 2023-01-30 | Ildong Pharmaceutical Co Ltd | Nuevo inhibidor de la secrecion de acido y uso del mismo. |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3285991A (en) | 1963-03-26 | 1966-11-15 | Union Carbide Corp | Polyepoxides cured with the reaction product of a dihydroxydiphenylsul-fone, an amine, and an aldehyde |
| US4847289A (en) | 1987-06-08 | 1989-07-11 | Merck & Co., Inc. | Thiophene sulfonamide antiglaucoma agents |
| CN1071924A (zh) | 1991-10-29 | 1993-05-12 | 纳幕尔杜邦公司 | 除草的三唑羧酸酰胺 |
| RU2157368C2 (ru) | 1994-09-26 | 2000-10-10 | Сионоги Энд Ко., Лтд. | Производные имидазола и фармацевтическая композиция на их основе |
| JPH0948778A (ja) | 1995-08-04 | 1997-02-18 | Sagami Chem Res Center | ２−置換−３−アルコキシ−５−（ピロール−２−イル）フラン誘導体 |
| JP4533466B2 (ja) | 1995-11-06 | 2010-09-01 | ユニバーシティ オブ ピッツバーグ | 蛋白質イソプレニルトランスフェラーゼの阻害剤 |
| CN1246847A (zh) | 1996-12-23 | 2000-03-08 | 杜邦药品公司 | 作为Xa因子抑制剂的含氮杂芳族化合物 |
| WO1999042461A1 (fr) | 1998-02-23 | 1999-08-26 | Warner-Lambert Company | Derives de quinoxaline substitues utilises comme antagonistes du recepteur de l'interleukine-8 |
| WO2004012659A2 (fr) | 2002-08-01 | 2004-02-12 | Nitromed, Inc. | Inhibiteurs nitroses de la pompe a protons, compositions et procedes d'utilisation |
| ATE410161T1 (de) | 2003-05-02 | 2008-10-15 | Elan Pharm Inc | 4-bromo-5-(2-chloro-benzoylamino)-1h-pyrazol-3- carbonsäureamid-derivate und verwandte verbindungen als bradykinin b1 rezeptor antagonisten zur behandlung von entzündlichen erkrankungen |
| JP4716996B2 (ja) | 2003-05-26 | 2011-07-06 | 武田薬品工業株式会社 | スルホピロール |
| JP4836788B2 (ja) | 2003-07-23 | 2011-12-14 | エグゼリクシス， インコーポレイテッド | 未分化リンパ腫キナーゼ変調因子及びその使用法 |
| WO2006036024A1 (fr) | 2004-09-30 | 2006-04-06 | Takeda Pharmaceutical Company Limited | Inhibiteurs de pompe a protons |
| AU2006285641A1 (en) * | 2005-08-30 | 2007-03-08 | Takeda Pharmaceutical Company Limited | 1-heterocyclylsulfonyl, 2-aminomethyl, 5- (hetero-) aryl substituted 1-h-pyrrole derivatives as acid secretion inhibitors |
| WO2007114338A1 (fr) * | 2006-03-31 | 2007-10-11 | Takeda Pharmaceutical Company Limited | Inhibiteur de secretion d'acide |
| US8933105B2 (en) * | 2007-02-28 | 2015-01-13 | Takeda Pharmaceutical Company Limited | Pyrrole compounds |
| JP2009077078A (ja) | 2007-09-19 | 2009-04-09 | Brother Ind Ltd | 位置検出システム |
| WO2009041705A2 (fr) * | 2007-09-28 | 2009-04-02 | Takeda Pharmaceutical Company Limited | Composé hétérocyclique à 5 chaînons |
| WO2009041447A1 (fr) | 2007-09-28 | 2009-04-02 | Takeda Pharmaceutical Company Limited | Composé hétérocyclique à 5 chaînons |
| PE20091846A1 (es) | 2008-05-19 | 2009-12-16 | Plexxikon Inc | DERIVADOS DE PIRROLO[2,3-d]-PIRIMIDINA COMO MODULADORES DE CINASAS |
| KR20110036044A (ko) | 2008-07-18 | 2011-04-06 | 다케다 파머수티컬 컴패니 리미티드 | 벤즈아제핀 유도체들 및 히스타민 ｈ3 길항제로서 이들의 용도 |
-
2010
- 2010-03-25 SG SG2011067808A patent/SG174476A1/en unknown
- 2010-03-25 WO PCT/JP2010/055257 patent/WO2010110378A1/fr not_active Ceased
- 2010-03-25 NZ NZ595890A patent/NZ595890A/xx not_active IP Right Cessation
- 2010-03-25 PE PE2011001696A patent/PE20120618A1/es not_active Application Discontinuation
- 2010-03-25 CN CN201080023162.7A patent/CN102448953B/zh active Active
- 2010-03-25 CA CA2756086A patent/CA2756086A1/fr not_active Abandoned
- 2010-03-25 AU AU2010228220A patent/AU2010228220B2/en not_active Ceased
- 2010-03-25 US US13/260,507 patent/US8895588B2/en active Active
- 2010-03-25 UA UAA201112488A patent/UA107457C2/uk unknown
- 2010-03-25 EP EP10756174.8A patent/EP2412713B1/fr active Active
- 2010-03-25 BR BRPI1009090A patent/BRPI1009090A2/pt not_active IP Right Cessation
- 2010-03-25 MA MA34275A patent/MA33214B1/fr unknown
- 2010-03-25 JP JP2011506117A patent/JP5552481B2/ja active Active
- 2010-03-25 EA EA201171168A patent/EA019853B1/ru not_active IP Right Cessation
- 2010-03-25 MX MX2011009943A patent/MX2011009943A/es active IP Right Grant
- 2010-03-25 KR KR1020117024240A patent/KR101656906B1/ko active Active
- 2010-03-25 GE GEAP201012426A patent/GEP20156222B/en unknown
-
2011
- 2011-08-25 EC EC2011011419A patent/ECSP11011419A/es unknown
- 2011-09-19 IL IL215235A patent/IL215235A/en not_active IP Right Cessation
- 2011-09-21 TN TN2011000474A patent/TN2011000474A1/fr unknown
- 2011-09-23 DO DO2011000296A patent/DOP2011000296A/es unknown
- 2011-09-23 CL CL2011002351A patent/CL2011002351A1/es unknown
- 2011-10-11 ZA ZA2011/07435A patent/ZA201107435B/en unknown
- 2011-10-12 CR CR20110533A patent/CR20110533A/es unknown
- 2011-10-26 CO CO11144548A patent/CO6460700A2/es active IP Right Grant
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA33072B1 (fr) | Composes pyridazinone | |
| MA32911B1 (fr) | Derives de benzothiazole convenant comme agents agents anticancereux | |
| MA31759B1 (fr) | Compose amide | |
| MA38540A1 (fr) | Dérivés de naphtyridine utiles comme antagonistes de l'intégrine alpha-v-bêta-6 | |
| MA31574B1 (fr) | Dérivés de pyrazole et leur utilisation comme inhibiteurs de raf | |
| MA31785B1 (fr) | Nouveaux dérivés d'imidazole | |
| MA37519B1 (fr) | Composés et compositions pour inhiber l'activité d'abl1, abl2 et bcr-abl1 | |
| MA34669B1 (fr) | Photostabilisants a base d'amines affichant un encombrement sterique a fonctionnalisation mixte | |
| MA33214B1 (fr) | Compose pyrazole | |
| MA34551B1 (fr) | Agent de lutte contre des organismes nuisibles | |
| MA33519B1 (fr) | Hétérocycles microbicides | |
| MA31690B1 (fr) | Nouveaux fongicides | |
| MA30984B1 (fr) | Compositions pesticides | |
| MA33851B1 (fr) | Compose heterocyclique contenant de l'azote et fongicide agricole | |
| MA35639B1 (fr) | Compose heterocyclique aromatique dihydroxy | |
| WO2009018909A3 (fr) | Dérivés d'alcools alkyliques de 1-phényl-2-pyridinyle en tant qu'inhibiteurs de la phosphodiestérase | |
| MA29141B1 (fr) | Pyrrolopyrazoles, servant de puissants inhibiteurs de kinases | |
| MA39172A1 (fr) | Dérivés bicycliques hétérocycliques comme inhibiteurs de bromodomaines | |
| MA29323B1 (fr) | Composes de l'acide pyridylacetique | |
| MA31444B1 (fr) | Agents de lutte contre les parasites invertebres | |
| MA37866B1 (fr) | Dérivés de type aza-indazole ou diaza-indazole pour le traitement de la douleur | |
| MA30589B1 (fr) | Azolylmethyloxirannes, leur utilisation pour la maitrise de champignons phytopathogenes, ainsi que produits les contenant. | |
| MA31596B1 (fr) | Nouveaux herbicides | |
| MA38935B1 (fr) | Dérivés de diazacarbazole à titre de ligands tau-pet | |
| MA32985B1 (fr) | Nouveaux microbiocides |