MA33214B1 - Compose pyrazole - Google Patents
Compose pyrazoleInfo
- Publication number
- MA33214B1 MA33214B1 MA34275A MA34275A MA33214B1 MA 33214 B1 MA33214 B1 MA 33214B1 MA 34275 A MA34275 A MA 34275A MA 34275 A MA34275 A MA 34275A MA 33214 B1 MA33214 B1 MA 33214B1
- Authority
- MA
- Morocco
- Prior art keywords
- atom
- hydrogen atom
- substituted
- halogen
- substituent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
LA PRÉSENTE INVENTION CONCERNE UN COMPOSÉ AYANT UNE EXCELLENTE ACTIVITÉ INHIBITRICE SUR LA SÉCRÉTION D'UN ACIDE ET PRÉSENTANT ENTRE AUTRES UNE ACTIVITÉ ANTITUMORALE. LA PRÉSENTE INVENTION CONCERNE SPÉCIFIQUEMENT UN COMPOSÉ REPRÉSENTÉ PAR LA FORMULE (1) [DANS LAQUELLE R1 REPRÉSENTE UN SUBSTITUANT; R2 REPRÉSENTE UN ATOME D'HYDROGÈNE, UN GROUPE ALKYLE EN C1 À C6 QUI PEUT ÊTRE SUBSTITUÉ PAR UN ATOME D'HALOGÈNE, OU UN GROUPE CYANO; ET R3 REPRÉSENTE UN ATOME D'HYDROGÈNE, UN ATOME D'HALOGÈNE, UN GROUPE CYANO, UN GROUPE ALKYLE EN C1 À C6 QUI PEUT ÊTRE SUBSTITUÉ PAR UN ATOME D'HALOGÈNE, UN GROUPE ALCOXY EN C1 À C6 QUI PEUT ÊTRE SUBSTITUÉ PAR UN ATOME D'HALOGÈNE; L'UN DES R2 ET R3 REPRÉSENTANT UN ATOME D'HYDROGÈNE ET L'AUTRE REPRÉSENTANT UN SUBSTITUANT AUTRE QU'UN ATOME D'HYDROGÈNE] OU UN SEL DE CELUI-CI.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009077078 | 2009-03-26 | ||
| PCT/JP2010/055257 WO2010110378A1 (fr) | 2009-03-26 | 2010-03-25 | Composé pyrazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA33214B1 true MA33214B1 (fr) | 2012-04-02 |
Family
ID=42781069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA34275A MA33214B1 (fr) | 2009-03-26 | 2010-03-25 | Compose pyrazole |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US8895588B2 (fr) |
| EP (1) | EP2412713B1 (fr) |
| JP (1) | JP5552481B2 (fr) |
| KR (1) | KR101656906B1 (fr) |
| CN (1) | CN102448953B (fr) |
| AU (1) | AU2010228220B2 (fr) |
| BR (1) | BRPI1009090A2 (fr) |
| CA (1) | CA2756086A1 (fr) |
| CL (1) | CL2011002351A1 (fr) |
| CO (1) | CO6460700A2 (fr) |
| CR (1) | CR20110533A (fr) |
| DO (1) | DOP2011000296A (fr) |
| EA (1) | EA019853B1 (fr) |
| EC (1) | ECSP11011419A (fr) |
| GE (1) | GEP20156222B (fr) |
| IL (1) | IL215235A (fr) |
| MA (1) | MA33214B1 (fr) |
| MX (1) | MX2011009943A (fr) |
| NZ (1) | NZ595890A (fr) |
| PE (1) | PE20120618A1 (fr) |
| SG (1) | SG174476A1 (fr) |
| TN (1) | TN2011000474A1 (fr) |
| UA (1) | UA107457C2 (fr) |
| WO (1) | WO2010110378A1 (fr) |
| ZA (1) | ZA201107435B (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ703528A (en) | 2012-06-27 | 2016-08-26 | Takeda Pharmaceutical | Liquid preparations of amines and organic acids stabilized by salts |
| WO2014052780A2 (fr) | 2012-09-27 | 2014-04-03 | Aratana Therapeutics, Inc. | Compositions et procédés d'utilisation d'un composé de lutte contre l'inappétence |
| ES2902795T3 (es) | 2015-01-28 | 2022-03-29 | Elanco Animal Health Incorporated | Composición para uso crónico como compuesto para aumentar de peso |
| CN105067814A (zh) * | 2015-07-24 | 2015-11-18 | 中国科学院成都生物研究所 | 解旋酶水解atp活性测定方法 |
| PT4148050T (pt) * | 2020-06-17 | 2025-01-29 | Ildong Pharmaceutical Co Ltd | Novo inibidor da secreção ácida e sua utilização |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3285991A (en) | 1963-03-26 | 1966-11-15 | Union Carbide Corp | Polyepoxides cured with the reaction product of a dihydroxydiphenylsul-fone, an amine, and an aldehyde |
| US4847289A (en) | 1987-06-08 | 1989-07-11 | Merck & Co., Inc. | Thiophene sulfonamide antiglaucoma agents |
| CN1071924A (zh) | 1991-10-29 | 1993-05-12 | 纳幕尔杜邦公司 | 除草的三唑羧酸酰胺 |
| BR9509024A (pt) | 1994-09-26 | 1997-09-30 | Shionogi & Co | Derivados de imidazol |
| JPH0948778A (ja) | 1995-08-04 | 1997-02-18 | Sagami Chem Res Center | ２−置換−３−アルコキシ−５−（ピロール−２−イル）フラン誘導体 |
| ATE236632T1 (de) | 1995-11-06 | 2003-04-15 | Univ Pittsburgh | Inhibitoren der protein-isoprenyl-transferase |
| CA2275796A1 (fr) | 1996-12-23 | 1998-07-02 | Donald Joseph Phillip Pinto | Composes heteroaromatiques contenant de l'azote, utilises en tant qu'inhibiteurs du facteur xa |
| AU1918299A (en) | 1998-02-23 | 1999-09-06 | Warner-Lambert Company | Substituted quinoxaline derivatives as interleukin-8 receptor antagonists |
| AU2003254282A1 (en) | 2002-08-01 | 2004-02-23 | Nitromed, Inc. | Nitrosated proton pump inhibitors, compositions and methods of use |
| ATE410161T1 (de) | 2003-05-02 | 2008-10-15 | Elan Pharm Inc | 4-bromo-5-(2-chloro-benzoylamino)-1h-pyrazol-3- carbonsäureamid-derivate und verwandte verbindungen als bradykinin b1 rezeptor antagonisten zur behandlung von entzündlichen erkrankungen |
| US7612064B2 (en) | 2003-05-26 | 2009-11-03 | Takeda Pharmaceutical Company Limited | Sulfopyrroles |
| US7872014B2 (en) | 2003-07-23 | 2011-01-18 | Exelixis, Inc. | Anaplastic lymphoma kinase modulators and methods of use |
| JP5173192B2 (ja) | 2004-09-30 | 2013-03-27 | 武田薬品工業株式会社 | プロトンポンプ阻害薬 |
| KR101115857B1 (ko) * | 2005-08-30 | 2012-04-12 | 다케다 야쿠힌 고교 가부시키가이샤 | 산 분비 억제제로서 1-헤테로시클릴술포닐, 2-아미노메틸,5-(헤테로-) 아릴 치환된 1-ｈ-피롤 유도체 |
| US7994205B2 (en) | 2006-03-31 | 2011-08-09 | Takeda Pharmaceutical Company Limited | Aryl-or heteroaryl-sulfonyl compounds as acid secretion inhibitors |
| US8933105B2 (en) * | 2007-02-28 | 2015-01-13 | Takeda Pharmaceutical Company Limited | Pyrrole compounds |
| JP2009077078A (ja) | 2007-09-19 | 2009-04-09 | Brother Ind Ltd | 位置検出システム |
| JP5345140B2 (ja) * | 2007-09-28 | 2013-11-20 | 武田薬品工業株式会社 | プロトンポンプ阻害剤としての５員複素環化合物 |
| JP5379690B2 (ja) | 2007-09-28 | 2013-12-25 | 武田薬品工業株式会社 | ５員複素環化合物 |
| PE20091846A1 (es) | 2008-05-19 | 2009-12-16 | Plexxikon Inc | DERIVADOS DE PIRROLO[2,3-d]-PIRIMIDINA COMO MODULADORES DE CINASAS |
| US20110124626A1 (en) | 2008-07-18 | 2011-05-26 | Takeda Pharmaceutical Company Limited | Benzazepine derivatives and their use as histamine h3 antagonists |
-
2010
- 2010-03-25 WO PCT/JP2010/055257 patent/WO2010110378A1/fr not_active Ceased
- 2010-03-25 US US13/260,507 patent/US8895588B2/en active Active
- 2010-03-25 AU AU2010228220A patent/AU2010228220B2/en not_active Ceased
- 2010-03-25 EP EP10756174.8A patent/EP2412713B1/fr active Active
- 2010-03-25 CA CA2756086A patent/CA2756086A1/fr not_active Abandoned
- 2010-03-25 BR BRPI1009090A patent/BRPI1009090A2/pt not_active IP Right Cessation
- 2010-03-25 UA UAA201112488A patent/UA107457C2/uk unknown
- 2010-03-25 MX MX2011009943A patent/MX2011009943A/es active IP Right Grant
- 2010-03-25 CN CN201080023162.7A patent/CN102448953B/zh active Active
- 2010-03-25 JP JP2011506117A patent/JP5552481B2/ja active Active
- 2010-03-25 PE PE2011001696A patent/PE20120618A1/es not_active Application Discontinuation
- 2010-03-25 KR KR1020117024240A patent/KR101656906B1/ko active Active
- 2010-03-25 SG SG2011067808A patent/SG174476A1/en unknown
- 2010-03-25 EA EA201171168A patent/EA019853B1/ru not_active IP Right Cessation
- 2010-03-25 MA MA34275A patent/MA33214B1/fr unknown
- 2010-03-25 GE GEAP201012426A patent/GEP20156222B/en unknown
- 2010-03-25 NZ NZ595890A patent/NZ595890A/xx not_active IP Right Cessation
-
2011
- 2011-08-25 EC EC2011011419A patent/ECSP11011419A/es unknown
- 2011-09-19 IL IL215235A patent/IL215235A/en not_active IP Right Cessation
- 2011-09-21 TN TN2011000474A patent/TN2011000474A1/fr unknown
- 2011-09-23 CL CL2011002351A patent/CL2011002351A1/es unknown
- 2011-09-23 DO DO2011000296A patent/DOP2011000296A/es unknown
- 2011-10-11 ZA ZA2011/07435A patent/ZA201107435B/en unknown
- 2011-10-12 CR CR20110533A patent/CR20110533A/es unknown
- 2011-10-26 CO CO11144548A patent/CO6460700A2/es active IP Right Grant
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