MA33214B1 - Compose pyrazole - Google Patents
Compose pyrazoleInfo
- Publication number
- MA33214B1 MA33214B1 MA34275A MA34275A MA33214B1 MA 33214 B1 MA33214 B1 MA 33214B1 MA 34275 A MA34275 A MA 34275A MA 34275 A MA34275 A MA 34275A MA 33214 B1 MA33214 B1 MA 33214B1
- Authority
- MA
- Morocco
- Prior art keywords
- atom
- hydrogen atom
- substituted
- halogen
- substituent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
LA PRÉSENTE INVENTION CONCERNE UN COMPOSÉ AYANT UNE EXCELLENTE ACTIVITÉ INHIBITRICE SUR LA SÉCRÉTION D'UN ACIDE ET PRÉSENTANT ENTRE AUTRES UNE ACTIVITÉ ANTITUMORALE. LA PRÉSENTE INVENTION CONCERNE SPÉCIFIQUEMENT UN COMPOSÉ REPRÉSENTÉ PAR LA FORMULE (1) [DANS LAQUELLE R1 REPRÉSENTE UN SUBSTITUANT; R2 REPRÉSENTE UN ATOME D'HYDROGÈNE, UN GROUPE ALKYLE EN C1 À C6 QUI PEUT ÊTRE SUBSTITUÉ PAR UN ATOME D'HALOGÈNE, OU UN GROUPE CYANO; ET R3 REPRÉSENTE UN ATOME D'HYDROGÈNE, UN ATOME D'HALOGÈNE, UN GROUPE CYANO, UN GROUPE ALKYLE EN C1 À C6 QUI PEUT ÊTRE SUBSTITUÉ PAR UN ATOME D'HALOGÈNE, UN GROUPE ALCOXY EN C1 À C6 QUI PEUT ÊTRE SUBSTITUÉ PAR UN ATOME D'HALOGÈNE; L'UN DES R2 ET R3 REPRÉSENTANT UN ATOME D'HYDROGÈNE ET L'AUTRE REPRÉSENTANT UN SUBSTITUANT AUTRE QU'UN ATOME D'HYDROGÈNE] OU UN SEL DE CELUI-CI.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009077078 | 2009-03-26 | ||
| PCT/JP2010/055257 WO2010110378A1 (fr) | 2009-03-26 | 2010-03-25 | Composé pyrazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA33214B1 true MA33214B1 (fr) | 2012-04-02 |
Family
ID=42781069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA34275A MA33214B1 (fr) | 2009-03-26 | 2010-03-25 | Compose pyrazole |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US8895588B2 (fr) |
| EP (1) | EP2412713B1 (fr) |
| JP (1) | JP5552481B2 (fr) |
| KR (1) | KR101656906B1 (fr) |
| CN (1) | CN102448953B (fr) |
| AU (1) | AU2010228220B2 (fr) |
| BR (1) | BRPI1009090A2 (fr) |
| CA (1) | CA2756086A1 (fr) |
| CL (1) | CL2011002351A1 (fr) |
| CO (1) | CO6460700A2 (fr) |
| CR (1) | CR20110533A (fr) |
| DO (1) | DOP2011000296A (fr) |
| EA (1) | EA019853B1 (fr) |
| EC (1) | ECSP11011419A (fr) |
| GE (1) | GEP20156222B (fr) |
| IL (1) | IL215235A (fr) |
| MA (1) | MA33214B1 (fr) |
| MX (1) | MX2011009943A (fr) |
| NZ (1) | NZ595890A (fr) |
| PE (1) | PE20120618A1 (fr) |
| SG (1) | SG174476A1 (fr) |
| TN (1) | TN2011000474A1 (fr) |
| UA (1) | UA107457C2 (fr) |
| WO (1) | WO2010110378A1 (fr) |
| ZA (1) | ZA201107435B (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201408511QA (en) | 2012-06-27 | 2015-01-29 | Takeda Pharmaceutical | Liquid preparations of amines and organic acids stabilized by salts |
| BR112015006282B1 (pt) * | 2012-09-27 | 2021-11-23 | Aratana Therapeutics, Inc | Composições e usos de capromorelina para controle de inapetência |
| US9700591B2 (en) | 2015-01-28 | 2017-07-11 | Aratana Therapeutics, Inc. | Compositions and methods for chronic use of a weight-gaining compound |
| CN105067814A (zh) * | 2015-07-24 | 2015-11-18 | 中国科学院成都生物研究所 | 解旋酶水解atp活性测定方法 |
| CN115884968B (zh) * | 2020-06-17 | 2024-06-21 | 日东制药株式会社 | 新型酸分泌抑制剂及其用途 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3285991A (en) | 1963-03-26 | 1966-11-15 | Union Carbide Corp | Polyepoxides cured with the reaction product of a dihydroxydiphenylsul-fone, an amine, and an aldehyde |
| US4847289A (en) | 1987-06-08 | 1989-07-11 | Merck & Co., Inc. | Thiophene sulfonamide antiglaucoma agents |
| MX9205392A (es) | 1991-10-29 | 1993-04-01 | Du Pont | Triazolcarbozamidas herbicidas y procedimiento para su obtencion. |
| DK0786455T3 (da) | 1994-09-26 | 2004-03-29 | Shionogi & Co | Imidazolderivater |
| JPH0948778A (ja) | 1995-08-04 | 1997-02-18 | Sagami Chem Res Center | ２−置換−３−アルコキシ−５−（ピロール−２−イル）フラン誘導体 |
| EP0873123B1 (fr) | 1995-11-06 | 2003-04-09 | University Of Pittsburgh | Inhibiteurs de proteine-isoprenyle-transferases |
| AU730224B2 (en) | 1996-12-23 | 2001-03-01 | Du Pont Pharmaceuticals Company | Nitrogen containing heteroaromatics as factor Xa inhibitors |
| WO1999042461A1 (fr) | 1998-02-23 | 1999-08-26 | Warner-Lambert Company | Derives de quinoxaline substitues utilises comme antagonistes du recepteur de l'interleukine-8 |
| EP1534278A4 (fr) | 2002-08-01 | 2006-09-06 | Nitromed Inc | Inhibiteurs nitroses de la pompe a protons, compositions et procedes d'utilisation |
| JP2006526015A (ja) | 2003-05-02 | 2006-11-16 | エラン ファーマシューティカルズ，インコーポレイテッド | 炎症疾患治療のためのブラジキニンｂ１受容体アンタゴニストとしての４−ブロモ−５−（２−クロロ−ベンゾイルアミノ）−１ｈ−ピラゾール−３−カルボン酸アミド誘導体および関連化合物 |
| EP1628957B1 (fr) | 2003-05-26 | 2010-09-29 | Takeda Pharmaceutical Company Limited | Derives de sulfopyrrole |
| EP1648455A4 (fr) | 2003-07-23 | 2009-03-04 | Exelixis Inc | Modulateurs de la proteine alk (anaplastic lymphoma kinase) et leurs methodes d'utilisation |
| KR101178747B1 (ko) | 2004-09-30 | 2012-09-03 | 다케다 야쿠힌 고교 가부시키가이샤 | 프로톤 펌프 저해제 |
| PE20070540A1 (es) | 2005-08-30 | 2007-06-26 | Takeda Pharmaceutical | Derivados de pirrol como inhibidores de la secrecion acida |
| WO2007114338A1 (fr) | 2006-03-31 | 2007-10-11 | Takeda Pharmaceutical Company Limited | Inhibiteur de secretion d'acide |
| US8933105B2 (en) | 2007-02-28 | 2015-01-13 | Takeda Pharmaceutical Company Limited | Pyrrole compounds |
| JP2009077078A (ja) | 2007-09-19 | 2009-04-09 | Brother Ind Ltd | 位置検出システム |
| JP5345140B2 (ja) | 2007-09-28 | 2013-11-20 | 武田薬品工業株式会社 | プロトンポンプ阻害剤としての５員複素環化合物 |
| EP2196459B1 (fr) | 2007-09-28 | 2016-11-02 | Takeda Pharmaceutical Company Limited | Composé hétérocyclique à 5 chaînons |
| PE20091846A1 (es) | 2008-05-19 | 2009-12-16 | Plexxikon Inc | DERIVADOS DE PIRROLO[2,3-d]-PIRIMIDINA COMO MODULADORES DE CINASAS |
| EP2326625A1 (fr) | 2008-07-18 | 2011-06-01 | Takeda Pharmaceutical Company Limited | Dérivés de benzazépine et leur utilisation comme antagonistes des récepteurs h3 de l'histamine |
-
2010
- 2010-03-25 EP EP10756174.8A patent/EP2412713B1/fr active Active
- 2010-03-25 PE PE2011001696A patent/PE20120618A1/es not_active Application Discontinuation
- 2010-03-25 WO PCT/JP2010/055257 patent/WO2010110378A1/fr not_active Ceased
- 2010-03-25 AU AU2010228220A patent/AU2010228220B2/en not_active Ceased
- 2010-03-25 KR KR1020117024240A patent/KR101656906B1/ko active Active
- 2010-03-25 JP JP2011506117A patent/JP5552481B2/ja active Active
- 2010-03-25 NZ NZ595890A patent/NZ595890A/xx not_active IP Right Cessation
- 2010-03-25 GE GEAP201012426A patent/GEP20156222B/en unknown
- 2010-03-25 UA UAA201112488A patent/UA107457C2/uk unknown
- 2010-03-25 MX MX2011009943A patent/MX2011009943A/es active IP Right Grant
- 2010-03-25 CA CA2756086A patent/CA2756086A1/fr not_active Abandoned
- 2010-03-25 BR BRPI1009090A patent/BRPI1009090A2/pt not_active IP Right Cessation
- 2010-03-25 CN CN201080023162.7A patent/CN102448953B/zh active Active
- 2010-03-25 MA MA34275A patent/MA33214B1/fr unknown
- 2010-03-25 US US13/260,507 patent/US8895588B2/en active Active
- 2010-03-25 SG SG2011067808A patent/SG174476A1/en unknown
- 2010-03-25 EA EA201171168A patent/EA019853B1/ru not_active IP Right Cessation
-
2011
- 2011-08-25 EC EC2011011419A patent/ECSP11011419A/es unknown
- 2011-09-19 IL IL215235A patent/IL215235A/en not_active IP Right Cessation
- 2011-09-21 TN TN2011000474A patent/TN2011000474A1/fr unknown
- 2011-09-23 CL CL2011002351A patent/CL2011002351A1/es unknown
- 2011-09-23 DO DO2011000296A patent/DOP2011000296A/es unknown
- 2011-10-11 ZA ZA2011/07435A patent/ZA201107435B/en unknown
- 2011-10-12 CR CR20110533A patent/CR20110533A/es unknown
- 2011-10-26 CO CO11144548A patent/CO6460700A2/es active IP Right Grant
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