ME02274B - DERIVATI PURINA ZA UPOTREBU U LEČENJU ALERGIJSKIH, INFLAMATORNIH l INFEKTIVNIH BOLESTI - Google Patents

DERIVATI PURINA ZA UPOTREBU U LEČENJU ALERGIJSKIH, INFLAMATORNIH l INFEKTIVNIH BOLESTI

Info

Publication number
ME02274B
ME02274B MEP-2015-138A MEP13815A ME02274B ME 02274 B ME02274 B ME 02274B ME P13815 A MEP13815 A ME P13815A ME 02274 B ME02274 B ME 02274B
Authority
ME
Montenegro
Prior art keywords
treatment
compound defined
compound
allergic
infectious diseases
Prior art date
Application number
MEP-2015-138A
Other languages
English (en)
French (fr)
Inventor
Charlotte Jane Mitchell
Keith Biggadike
Diane Mary Coe
Xiao Qing Lewell
Stephen Allan Smith
Naimisha Trivedi
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41187189&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ME02274(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Publication of ME02274B publication Critical patent/ME02274B/me

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Claims (12)

1.Jedinjenje strukturekoje je 6-amino-2-{[(1S)-1-metilbutil]oksi}-9-[5-(1-piperidinil)pentil]-7,9-dihidro-8H-purin-8-on ili njegova so.
2.Jedinjenje prema patentnom zahtevu 1, koje je 6-amino-2-{[(1S)-1-metilbutil]oksi}-9-[5-(1-piperidinil)pentil]-7,9-dihidro-8H-purin-8-on, kao farmaceutski prihvatljiva so.
3.Jedinjenje prema patentnom zahtevu 1, koje je 6-amino-2-{[(1S)-1-metilbutil]oksi}-9-[5-(1-piperidinil)pentil]-7,9-dihidro-8H-purin-8-on, kao slobodna baza.
4.Jedinjenje definisano prema patentnom zahtevu 2 ili zahtevu 3 za primenu u terapiji.
5.Jedinjenje definisano prema patentom zahtevu 2 ili zahtevu 3 za upotrebu u lečenju alergijske bolesti i drugih inflamatornih stanja, infektivnih bolesti i kancera.
6.Jedinjenje definisano prema patentnom zahtevu 2 ili zahtevu 3 za upotrebu u lečenju alergijskog rinitisa.
7.Jedinjenje definisano prema patentnom zahtevu 2 ili 3 za upotrebu u lečenju astme.
8.Farmaceutska kompozicija koja sadrži jedinjenje definisano prema patentom zahtevu 2 ili zahtevu 3 i jedan ili više farmaceutski prihvatljivih sredstava za razblaživanje ili nosača.
9.Farmaceutska kompozicija prema patentnom zahtevu 8 koja je pogodna za intranazalno ili inhalaciono davanje.
10.Upotreba jedinjenja definisanog u patentnom zahtevu 2 ili zahtevu 3 za proizvodnju leka za lečenje alergijske bolesti i drugih inflamatornih stanja, infektivnih bolesti i kancera.
11.Upotreba jedinjenja definisanog prema patenom zahtevu 2 ili zahtevu 3 za proizvodnju leka za lečenje alergijskog rinitisa.
12.Upotreba jedinjenja definisanog u patentnom zahtevu 2 ili zahtevu 3 za proizvodnju leka za lečenje astme.
MEP-2015-138A 2008-08-11 2009-08-07 DERIVATI PURINA ZA UPOTREBU U LEČENJU ALERGIJSKIH, INFLAMATORNIH l INFEKTIVNIH BOLESTI ME02274B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8777708P 2008-08-11 2008-08-11
EP09781606.0A EP2324026B1 (en) 2008-08-11 2009-08-07 Purine derivatives for use in the treatment of allergic, inflammatory and infectious diseases
PCT/EP2009/060265 WO2010018133A1 (en) 2008-08-11 2009-08-07 Purine derivatives for use in the treatment of allergic, inflammatory and infectious diseases

Publications (1)

Publication Number Publication Date
ME02274B true ME02274B (me) 2016-02-20

Family

ID=41187189

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2015-138A ME02274B (me) 2008-08-11 2009-08-07 DERIVATI PURINA ZA UPOTREBU U LEČENJU ALERGIJSKIH, INFLAMATORNIH l INFEKTIVNIH BOLESTI

Country Status (38)

Country Link
US (7) US8765772B2 (me)
EP (3) EP2324026B1 (me)
JP (1) JP5529867B2 (me)
KR (1) KR101669939B1 (me)
CN (2) CN104098568B (me)
AU (1) AU2009281197B2 (me)
BR (1) BRPI0917138A2 (me)
CA (1) CA2733749C (me)
CL (1) CL2011000301A1 (me)
CO (1) CO6351791A2 (me)
CR (1) CR20110116A (me)
CY (1) CY1119992T1 (me)
DK (2) DK2324026T3 (me)
DO (1) DOP2011000048A (me)
EA (1) EA020631B1 (me)
ES (2) ES2549154T3 (me)
HK (1) HK1253532A1 (me)
HR (2) HRP20150938T1 (me)
HU (2) HUE036570T2 (me)
IL (1) IL210757A (me)
LT (1) LT3000813T (me)
MA (1) MA32624B1 (me)
ME (1) ME02274B (me)
MX (2) MX2011001666A (me)
MY (1) MY162538A (me)
NO (1) NO3000813T3 (me)
NZ (2) NZ590782A (me)
PE (1) PE20110674A1 (me)
PL (2) PL3000813T3 (me)
PT (2) PT3000813T (me)
RS (2) RS56984B1 (me)
SG (1) SG192547A1 (me)
SI (2) SI3000813T1 (me)
SM (2) SMT201800123T1 (me)
TR (1) TR201802648T4 (me)
UA (1) UA103195C2 (me)
WO (1) WO2010018133A1 (me)
ZA (1) ZA201100845B (me)

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