NO126377B - - Google Patents

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Info

Publication number: NO126377B
Authority: NO; Norway
Prior art keywords: cross; inclusion; cyclodextrin; reaction; water
Prior art date: 1964-04-29

Application number

NO00157873A

Other languages

English (en)

Norwegian (no)

Inventor

Juergen Solms

Original Assignee

Nestle Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1964-04-29

Filing date

1965-04-28

Publication date

1973-01-29

1965-04-28 Application filed by Nestle Sa filed Critical Nestle Sa

1973-01-29 Publication of NO126377B publication Critical patent/NO126377B/no

Links

229920000858 Cyclodextrin Polymers 0.000 claims description 26
229920005989 resin Polymers 0.000 claims description 25
239000011347 resin Substances 0.000 claims description 25
150000001875 compounds Chemical class 0.000 claims description 24
WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 claims description 22
238000006243 chemical reaction Methods 0.000 claims description 14
239000003431 cross linking reagent Substances 0.000 claims description 12
HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 claims description 11
125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 10
238000000034 method Methods 0.000 claims description 8
230000001588 bifunctional effect Effects 0.000 claims description 7
BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 claims description 3
230000002378 acidificating effect Effects 0.000 claims description 2
239000003463 adsorbent Substances 0.000 claims description 2
239000003223 protective agent Substances 0.000 claims description 2
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 14
239000000203 mixture Substances 0.000 description 13
CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 11
229940097362 cyclodextrins Drugs 0.000 description 11
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 9
239000000126 substance Substances 0.000 description 9
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 8
239000000243 solution Substances 0.000 description 6
239000000843 powder Substances 0.000 description 5
150000001720 carbohydrates Chemical class 0.000 description 4
235000014633 carbohydrates Nutrition 0.000 description 4
238000004132 cross linking Methods 0.000 description 4
239000000376 reactant Substances 0.000 description 4
239000002904 solvent Substances 0.000 description 4
238000001179 sorption measurement Methods 0.000 description 4
LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
238000004519 manufacturing process Methods 0.000 description 3
239000000725 suspension Substances 0.000 description 3
DEWLEGDTCGBNGU-UHFFFAOYSA-N 1,3-dichloropropan-2-ol Chemical compound ClCC(O)CCl DEWLEGDTCGBNGU-UHFFFAOYSA-N 0.000 description 2
LSTZTHCEEPHCNQ-UHFFFAOYSA-N 3-(2,5-dioxabicyclo[2.1.0]pentan-3-yloxy)-2,5-dioxabicyclo[2.1.0]pentane Chemical compound C1(C2C(O2)O1)OC1C2C(O2)O1 LSTZTHCEEPHCNQ-UHFFFAOYSA-N 0.000 description 2
CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
239000004593 Epoxy Substances 0.000 description 2
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
238000004587 chromatography analysis Methods 0.000 description 2
150000002118 epoxides Chemical group 0.000 description 2
238000002955 isolation Methods 0.000 description 2
238000003756 stirring Methods 0.000 description 2
FSBYOEHUNSUUTD-UHFFFAOYSA-N 2-(2,5-dioxabicyclo[2.1.0]pentan-3-yloxy)ethanol Chemical compound C1(C2C(O2)O1)OCCO FSBYOEHUNSUUTD-UHFFFAOYSA-N 0.000 description 1
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 1
239000004971 Cross linker Substances 0.000 description 1
ZFIVKAOQEXOYFY-UHFFFAOYSA-N Diepoxybutane Chemical compound C1OC1C1OC1 ZFIVKAOQEXOYFY-UHFFFAOYSA-N 0.000 description 1
239000002253 acid Substances 0.000 description 1
239000007864 aqueous solution Substances 0.000 description 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
239000001569 carbon dioxide Substances 0.000 description 1
229910002092 carbon dioxide Inorganic materials 0.000 description 1
125000001309 chloro group Chemical group Cl* 0.000 description 1
239000000470 constituent Substances 0.000 description 1
238000010908 decantation Methods 0.000 description 1
238000004821 distillation Methods 0.000 description 1
-1 e.g. vitamins Chemical class 0.000 description 1
230000000694 effects Effects 0.000 description 1
239000000839 emulsion Substances 0.000 description 1
230000002255 enzymatic effect Effects 0.000 description 1
238000001914 filtration Methods 0.000 description 1
239000008098 formaldehyde solution Substances 0.000 description 1
239000008187 granular material Substances 0.000 description 1
125000005843 halogen group Chemical group 0.000 description 1
239000011261 inert gas Substances 0.000 description 1
WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 1
230000007935 neutral effect Effects 0.000 description 1
JCXJVPUVTGWSNB-UHFFFAOYSA-N nitrogen dioxide Inorganic materials O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 description 1
239000003960 organic solvent Substances 0.000 description 1
230000001590 oxidative effect Effects 0.000 description 1
239000001301 oxygen Substances 0.000 description 1
229910052760 oxygen Inorganic materials 0.000 description 1
239000011541 reaction mixture Substances 0.000 description 1
230000035484 reaction time Effects 0.000 description 1
230000000717 retained effect Effects 0.000 description 1
150000003384 small molecules Chemical class 0.000 description 1
230000000087 stabilizing effect Effects 0.000 description 1
239000007858 starting material Substances 0.000 description 1
229920003002 synthetic resin Polymers 0.000 description 1
239000000057 synthetic resin Substances 0.000 description 1
239000011782 vitamin Substances 0.000 description 1
229940088594 vitamin Drugs 0.000 description 1
229930003231 vitamin Natural products 0.000 description 1
235000013343 vitamin Nutrition 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/70—Fixation, conservation, or encapsulation of flavouring agents
- A23L27/72—Encapsulation
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/70—Fixation, conservation, or encapsulation of flavouring agents
- A23L27/74—Fixation, conservation, or encapsulation of flavouring agents with a synthetic polymer matrix or excipient, e.g. vinylic, acrylic polymers
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/70—Fixation, conservation, or encapsulation of flavouring agents
- A23L27/75—Fixation, conservation, or encapsulation of flavouring agents the flavouring agents being bound to a host by chemical, electrical or like forces, e.g. use of precursors
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/16—Separation; Purification; Stabilisation; Use of additives
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/16—Cyclodextrin; Derivatives thereof

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Polymers & Plastics (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Nutrition Science (AREA)
Medicinal Chemistry (AREA)
Food Science & Technology (AREA)
Materials Engineering (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Analytical Chemistry (AREA)
Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Treatment Of Liquids With Adsorbents In General (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

NO00157873A 1964-04-29 1965-04-28 NO126377B (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH561564A CH445129A (fr)	1964-04-29	1964-04-29	Procédé pour la préparation de composés d'inclusion à poids moléculaire élevé

Publications (1)

Publication Number	Publication Date
NO126377B true NO126377B (fr)	1973-01-29

Family

ID=4296563

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO00157873A NO126377B (fr)	1964-04-29	1965-04-28
NO00170961A NO127814B (fr)	1964-04-29	1967-12-13

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
NO00170961A NO127814B (fr)	1964-04-29	1967-12-13

Country Status (10)

Country	Link
US (1)	US3420788A (fr)
BE (1)	BE662174A (fr)
CH (1)	CH445129A (fr)
DK (1)	DK132259C (fr)
ES (1)	ES312034A1 (fr)
GB (1)	GB1091637A (fr)
IT (1)	IT961352B (fr)
NL (1)	NL6505361A (fr)
NO (2)	NO126377B (fr)
SE (2)	SE333240B (fr)

Families Citing this family (115)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU177419B (en) *	1978-07-13	1981-10-28	Chinoin Gyogyszer Es Vegyeszet	Process for preparing threedimensional,retentive polymers consisting of cyclodextrin and polyvinylalcohol units,capable of forming inclusion complexes in the form of bead,fibre or mainly block
EP0013688B1 (fr) *	1978-12-15	1984-02-01	Kyoshin Co., Ltd.	Produit parfumant à base de résines synthétiques et procédé pour la production dudit produit
JPS609524B2 (ja) *	1979-06-01	1985-03-11	理化学研究所	シクロデキストリンの回収法
HU184066B (en) *	1979-12-28	1984-06-28	Chinoin Gyogyszer Es Vegyeszet	Plant growth regulating substance and process for preparing such compound
HU181733B (en) *	1980-08-07	1983-11-28	Chinoin Gyogyszer Es Vegyeszet	Process for preparing sorbents containing cyclodextrin on cellulose base
JPS57130914A (en) *	1981-02-04	1982-08-13	Agency Of Ind Science & Technol	Prolongation of activity retention
HU189534B (en) *	1981-09-09	1986-07-28	Chinoin Rt.,Hu	Process for producing new tablets containing cyclodextrin polymer as desintegrator
US4448789A (en) *	1982-08-27	1984-05-15	Warner-Lambert Company	Enhanced flavor-releasing agent
HU191101B (en) *	1983-02-14	1987-01-28	Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu	Process for preparing water-soluble cyclodextrin polymers substituted with ionic groups
JPS6081166A (ja) *	1983-10-11	1985-05-09	Fujisawa Pharmaceut Co Ltd	２−ニトロオキシメチル−６−クロロピリジンのβ−シクロデキストリン包接化合物およびその製造法
JPS60202115A (ja) *	1984-03-27	1985-10-12	Ichiro Shibauchi	エポキシ樹脂用硬化剤
US4596795A (en) *	1984-04-25	1986-06-24	The United States Of America As Represented By The Secretary, Dept. Of Health & Human Services	Administration of sex hormones in the form of hydrophilic cyclodextrin derivatives
US4727064A (en) *	1984-04-25	1988-02-23	The United States Of America As Represented By The Department Of Health And Human Services	Pharmaceutical preparations containing cyclodextrin derivatives
JPS61152765A (ja) *	1984-12-27	1986-07-11	Nippon Ekishiyou Kk	シクロデキストリン類で包接された化合物を含有した合成樹脂製品及びその製造方法
US4769474A (en) *	1985-04-10	1988-09-06	Mitsui Toatsu Chemicals, Inc.	Process for purifying tryptophane
SE452469B (sv) *	1986-06-18	1987-11-30	Pharmacia Ab	Material bestaende av en tverbunden karboxylgrupphaltig polysackarid och forfarande vid framstellning av detsamma
US4897472A (en) *	1986-11-19	1990-01-30	Oy Alko Ab	Process for isolation and purification of cyclodextrins
US5273820A (en) *	1986-12-08	1993-12-28	American Maize-Products Company	Separation and purification of cyclodextrins
US4808232A (en) *	1986-12-08	1989-02-28	American Maize-Products Company	Separation and purification of cyclodextrins
US4898921A (en) *	1987-06-03	1990-02-06	Montclair State College	Conducting polymer films, method of manufacture and applications therefor
US5760015A (en) *	1988-01-19	1998-06-02	The Trustees Of The University Of Pennsylvania	Cyclodextrin compounds and methods of making and use thereof
US5658894A (en) *	1989-04-23	1997-08-19	The Trustees Of The University Of Pennsylvania	Compositions for inhibiting restenosis
US5637575A (en) *	1988-01-19	1997-06-10	The Trustees Of The University Of Pennsylvania	Methods of inhibiting restenosis
JPH0269540A (ja) *	1988-09-05	1990-03-08	Chisso Corp	結晶性ポリオレフイン組成物
US5441944A (en) *	1989-04-23	1995-08-15	The Trustees Of The University Of Pennsylvania	Substituted cyclodextrin sulfates and their uses as growth modulating agents
US5075432A (en) *	1989-08-11	1991-12-24	Edward Vanzo	Spherical cyclodextrin polymer beads
IT1255981B (it) *	1991-04-30	1995-11-17	Ministero Dell Uni E Della	Composizione adesiva a piu' componenti
US5446030A (en) *	1991-09-19	1995-08-29	Weisz; Paul B.	Prevention of hemolysis
BR9405858A (pt) *	1993-03-31	1995-12-12	Univ Pennsylvania	Processos de afetar o crescimento de tecido vivo em mamiferos compostos e composiçÕes para os mesmos
US5492947A (en) *	1994-06-23	1996-02-20	Aspen Research Corporation	Barrier material comprising a thermoplastic and a compatible cyclodextrin derivative
US6048736A (en) *	1998-04-29	2000-04-11	Kosak; Kenneth M.	Cyclodextrin polymers for carrying and releasing drugs
WO2004064816A1 (fr) *	2003-01-16	2004-08-05	Cornell Research Foundation, Inc.	Hydrogel partiellement biodegradable sensible a la temperature et au ph
WO2005014782A2 (fr)	2003-06-13	2005-02-17	Alnylam Europe Ag.,	Acide ribonucleique double brin presentant une efficacite accrue dans un organisme
WO2005060968A1 (fr)	2003-12-11	2005-07-07	Sepracor Inc.	Combinaison d'un sedatif et d'un modulateur des neurotransmetteurs, et methodes permettant d'ameliorer la qualite du sommeil et de traiter la depression
EP2610234A1 (fr)	2004-02-24	2013-07-03	The General Hospital Corporation	Radiofluoration catalytique
CA2562151C (fr)	2004-04-30	2016-09-06	Alnylam Pharmaceuticals, Inc.	Oligonucleotides comportant une pyrimidine a modification c5
BRPI0511070A (pt)	2004-06-17	2007-11-27	Infinity Pharmaceuticals Inc	compostos e processos para inibição da interação de proteìnas bcl com parceiros de ligação
CA2598270A1 (fr) *	2005-02-18	2006-08-24	Surface Logix, Inc.	Procedes de fabrication de composes a amelioration pharmacocinetique comportant des residus ou groupes fonctionnels et compositions pharmaceutiques comportant lesdits composes
KR20080016531A (ko) *	2005-02-18	2008-02-21	서피스 로직스, 인크.	약동학적으로 개선된 화합물
ES2310948B2 (es) *	2005-02-25	2009-09-16	Universidade De Santiago De Compostela	Procedimiento de obtencion de hidrogeles de ciclodextrinas con glicidileteres, las composiciones obtenidas y sus aplicaciones.
US8669236B2 (en) *	2005-05-12	2014-03-11	The General Hospital Corporation	Biotinylated compositions
KR100791978B1 (ko) *	2005-06-21	2008-01-04	곽해수	콜레스테롤 제거용 베타-싸이클로덱스트린의 가교화 및그의 재생방법
AU2007281212B8 (en)	2006-08-03	2013-02-28	Trustees Of Tufts College	Non-flushing niacin analogues, and methods of use thereof
KR100785913B1 (ko) *	2006-11-29	2007-12-17	한국과학기술연구원	경화된 β-사이클로덱스트린 중합체 분말과 그의 제조방법
WO2009013770A1 (fr) *	2007-07-26	2009-01-29	Humanitas Mirasole S.P.A.	Matériau polysaccharidique dérivé pour l'administration transdermique de médicaments
US20090060860A1 (en) *	2007-08-31	2009-03-05	Eva Almenar	Beta-cyclodextrins as nucleating agents for poly(lactic acid)
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JP5991922B2 (ja)	2009-11-13	2016-09-14	サレプタセラピューティクス，インコーポレイテッド	アンチセンス抗ウイルス性化合物およびインフルエンザウイルス感染を処置するための方法
EP2545173A2 (fr)	2010-03-12	2013-01-16	Sarepta Therapeutics, Inc.	Modulation anti-sens de récepteurs hormonaux nucléaires
ES2816898T3 (es)	2010-05-13	2021-04-06	Sarepta Therapeutics Inc	Compuestos que modulan la actividad de señalización de las interleucinas 17 y 23
US8450316B2 (en)	2010-06-24	2013-05-28	Trustees Of Tufts College	Niacin mimetics, and methods of use thereof
WO2011163612A1 (fr)	2010-06-24	2011-12-29	Trustees Of Tufts College	Mimétiques de niacine et leurs procédés d'utilisation
WO2012100142A2 (fr)	2011-01-20	2012-07-26	Cornell University	Traitements de troubles rétiniens
EP2732035A2 (fr)	2011-07-15	2014-05-21	Sarepta Therapeutics, Inc.	Procédés et compositions pour manipulation de la traduction d'isoformes de protéines à partir de sites initiateurs alternatifs d'initiation
WO2013086441A2 (fr)	2011-12-08	2013-06-13	Sarepta Therapeutics, Inc.	Analogues d'oligonucléotide ciblant lmna humain
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AU2012355615A1 (en)	2011-12-23	2014-07-10	Novartis Ag	Compounds for inhibiting the interaction of BCL2 with binding partners
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US9126979B2 (en)	2011-12-23	2015-09-08	Novartis Ag	Compounds for inhibiting the interaction of BCL2 with binding partners
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JP2016502858A (ja)	2012-12-20	2016-02-01	サレプタセラピューティクス，インコーポレイテッド	筋ジストロフィを処置するための改善されたエキソンスキッピング組成物
FR2999916B1 (fr)	2012-12-20	2015-01-30	Oreal	Composition permettant la liberation d'agent benefique comprenant un polycondensat de cyclodextrine insoluble dans l'eau et au moins un agent benefique
HUE039052T2 (hu)	2013-02-19	2018-12-28	Novartis Ag	Benzotiofénszármazékok és azok készítményei szelektív ösztrogén receptor lebontóként
HRP20190382T1 (hr)	2013-03-14	2019-04-19	Sarepta Therapeutics, Inc.	Pripravci koji preskaču ekson za liječenje mišićne distrofije
EA202090946A3 (ru)	2013-03-14	2021-07-30	Сарепта Терапьютикс, Инк.	Композиции, обеспечивающие пропускание экзонов, для лечения мышечной дистрофии
NZ631289A (en)	2013-03-15	2017-08-25	Sarepta Therapeutics Inc	Improved compositions for treating muscular dystrophy
US9227969B2 (en)	2013-08-14	2016-01-05	Novartis Ag	Compounds and compositions as inhibitors of MEK
WO2015022663A1 (fr)	2013-08-14	2015-02-19	Novartis Ag	Composés et compositions utiles comme inhibiteurs de mek
WO2015022664A1 (fr)	2013-08-14	2015-02-19	Novartis Ag	Composés et compositions utiles comme inhibiteurs de mek
WO2015092634A1 (fr)	2013-12-16	2015-06-25	Novartis Ag	Composés et compositions de 1,2,3,4-tétrahydroisoquinoléine en tant qu'antagonistes et agents de dégradation sélectifs des récepteurs des œstrogènes
EP3094629B1 (fr)	2014-01-17	2018-08-22	Novartis AG	Dérivés de 1-(triazin-3-yl/pyridazin-3-yl)-piper(-azine)idine et compositions les contenant pour l'inhibition de l'activité de shp2
JO3517B1 (ar)	2014-01-17	2020-07-05	Novartis Ag	ان-ازاسبيرو الكان حلقي كبديل مركبات اريل-ان مغايرة وتركيبات لتثبيط نشاط shp2
EP3094627B1 (fr)	2014-01-17	2018-08-22	Novartis AG	Dérivés de 1-pyridazin-/triazin-3-yl-piper(-azine)/idine/pyrolidine et compositions les contenant pour l'inhibition de l'activité de shp2
EP3139924A4 (fr)	2014-05-06	2018-03-07	Anthony G. Visco	Procédés de traitement ou de prévention du travail prématuré
CA2981139A1 (fr) *	2015-04-01	2016-10-06	International Dioxide, Inc	Composition stabilisee pour lutte contre les odeurs et deshydratation renforcee combinees
US10287266B2 (en)	2015-06-19	2019-05-14	Novartis Ag	Compounds and compositions for inhibiting the activity of SHP2
JP6878316B2 (ja)	2015-06-19	2021-05-26	ノバルティスアーゲー	Ｓｈｐ２の活性を阻害するための化合物および組成物
ES2741746T3 (es)	2015-06-19	2020-02-12	Novartis Ag	Compuestos y composiciones para inhibir la actividad de SHP2
US20190054113A1 (en)	2015-09-30	2019-02-21	Sarepta Therapeutics, Inc.	Methods for treating muscular dystrophy
WO2017190041A1 (fr)	2016-04-29	2017-11-02	Sarepta Therapeutics, Inc.	Analogues d'oligonucléotide ciblant lmna humain
AU2017283769B2 (en)	2016-06-14	2019-08-15	Novartis Ag	Compounds and compositions for inhibiting the activity of SHP2
AU2017290231A1 (en)	2016-06-30	2019-02-07	Sarepta Therapeutics, Inc.	Exon skipping oligomers for muscular dystrophy
EP3554552B1 (fr)	2016-12-19	2022-08-17	Sarepta Therapeutics, Inc.	Conjugués oligomères de sauts d'exons pour la dystrophie musculaire
LT3554553T (lt)	2016-12-19	2022-08-25	Sarepta Therapeutics, Inc.	Egzoną šalinantys oligomero konjugatai nuo raumenų distrofojos
CN117298290A (zh)	2016-12-19	2023-12-29	萨勒普塔医疗公司	用于肌肉萎缩症的外显子跳跃寡聚体缀合物
CN110536694A (zh)	2017-04-20	2019-12-03	Atyr 医药公司	用于治疗肺部炎症的组合物和方法
EA201991450A1 (ru)	2017-09-22	2019-12-30	Сарепта Терапьютикс, Инк.	Конъюгаты олигомеров для пропуска экзона при мышечной дистрофии
EP3687577A1 (fr)	2017-09-28	2020-08-05	Sarepta Therapeutics, Inc.	Polythérapies pour traiter une dystrophie musculaire
JP2020536057A (ja)	2017-09-28	2020-12-10	サレプタセラピューティクス，インコーポレイテッド	筋ジストロフィーを処置するための併用療法
JP2020536060A (ja)	2017-09-28	2020-12-10	サレプタセラピューティクス，インコーポレイテッド	筋ジストロフィーを処置するための併用療法
US10758629B2 (en)	2018-05-29	2020-09-01	Sarepta Therapeutics, Inc.	Exon skipping oligomer conjugates for muscular dystrophy
EP3806868A4 (fr)	2018-06-13	2022-06-22	Sarepta Therapeutics, Inc.	Oligomères induisant un saut d'exon pour la dystrophie musculaire
CN108435148A (zh) *	2018-06-21	2018-08-24	黄益良	一种环糊精改性聚丙烯酰胺污水处理剂及其制备方法
JP7490925B2 (ja)	2018-07-26	2024-05-28	エータイアーファーマ，インコーポレイテッド	Ｎｒｐ２関連疾患を治療するための組成物および方法
TW202020153A (zh)	2018-07-27	2020-06-01	美商薩羅塔治療公司	用於肌肉萎縮症之外顯子跳躍寡聚物
IL321667A (en)	2018-12-13	2025-08-01	Sarepta Therapeutics Inc	Exon skipping oligomer conjugates for muscular dystrophy
US11279774B2 (en)	2019-01-03	2022-03-22	Underdog Pharmaceuticals, Inc.	Cyclodextrin dimers, compositions thereof, and uses thereof
CN109663578B (zh) *	2019-02-22	2022-02-25	安徽大学	一种对刚果红超高吸附能力的混合卤化物(MV)[BiI3Cl2]的制备方法及其产品
CN109806849A (zh) *	2019-03-25	2019-05-28	东华大学	一种环糊精纳米空心小球及其制备方法
SG11202108757XA (en)	2019-03-28	2021-10-28	Sarepta Therapeutics Inc	Methods for treating muscular dystrophy with casimersen
US20220193246A1 (en)	2019-04-18	2022-06-23	Sarepta Therapeutics, Inc.	Compositions for treating muscular dystrophy
JP2022536495A (ja)	2019-06-19	2022-08-17	サレプタセラピューティクス，インコーポレイテッド	筋ジストロフィーを治療する方法
WO2021101606A1 (fr) *	2019-11-18	2021-05-27	Pmidg, Llc	Compositions pour composés d'écran solaire et méthodes associées
CN113019344A (zh) *	2021-03-16	2021-06-25	大连理工大学	一种具有选择性吸附的球形零价铁-环糊精复合材料的制备方法及应用
CN113372674B (zh) *	2021-08-13	2021-10-19	山东三义集团股份有限公司	一种氯化聚乙烯用高速挤出加工改性助剂的制备方法
JP2025509438A (ja)	2022-03-17	2025-04-11	サレプタセラピューティクス，インコーポレイテッド	ホスホロジアミデートモルホリノオリゴマーコンジュゲート
JP2025532906A (ja)	2022-09-28	2025-10-03	アルトスラブス，インコーポレーテッド	老齢／老化細胞における再生因子の発現
EP4642467A2 (fr)	2022-12-30	2025-11-05	Cornell University	Cyclodextrines acides pour le traitement de l'accumulation de lipofuscine et de maladies oculaires
CN120441878B (zh) *	2025-07-09	2025-10-17	成都飞机工业（集团）有限责任公司	一种去除无氰电镀镉溶液中金属杂质的聚合物树脂及其制备方法与使用方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2801184A (en) *	1952-01-18	1957-07-30	Miyamoto Katsuhei	Colloidal suspension of amylose and alpha-amylodextrin
NL224464A (fr) *	1958-01-29
US2977356A (en) *	1958-05-27	1961-03-28	Anheuser Busch	Process for preparing cross-linked starch ethers in granule form
US2973243A (en) *	1958-08-26	1961-02-28	Kudera Dieter	Process for producing threads, foils, tubes and the like from amylose and/or starch carbohydrates containing amylose
NL252506A (fr) *	1959-06-12
US2989521A (en) *	1959-06-30	1961-06-20	Frederic R Senti	Method of cross-linking and oxidizing starch
US3282870A (en) *	1963-11-29	1966-11-01	Dow Chemical Co	Starch and polycarboxamide reaction products

1964
- 1964-04-29 CH CH561564A patent/CH445129A/fr unknown
1965
- 1965-04-06 IT IT7649/65A patent/IT961352B/it active
- 1965-04-07 BE BE662174D patent/BE662174A/fr unknown
- 1965-04-20 US US449619A patent/US3420788A/en not_active Expired - Lifetime
- 1965-04-20 ES ES0312034A patent/ES312034A1/es not_active Expired
- 1965-04-20 GB GB16550/65A patent/GB1091637A/en not_active Expired
- 1965-04-27 NL NL6505361A patent/NL6505361A/xx unknown
- 1965-04-28 NO NO00157873A patent/NO126377B/no unknown
- 1965-04-28 SE SE5582/65A patent/SE333240B/xx unknown
- 1965-04-28 SE SE12182/69A patent/SE365234B/xx unknown
- 1965-04-28 DK DK215765A patent/DK132259C/da active
1967
- 1967-12-13 NO NO00170961A patent/NO127814B/no unknown

Also Published As

Publication number	Publication date
DE1493047B2 (de)	1973-01-11
DK132259B (da)	1975-11-17
NO127814B (fr)	1973-08-20
DK132259C (da)	1976-05-03
DE1493047A1 (de)	1969-01-02
NL6505361A (fr)	1965-11-01
BE662174A (fr)	1965-10-07
SE365234B (fr)	1974-03-18
ES312034A1 (es)	1966-02-01
CH445129A (fr)	1967-10-15
SE333240B (sv)	1971-03-08
IT961352B (it)	1973-12-10
US3420788A (en)	1969-01-07
GB1091637A (en)	1967-11-22

Publication	Publication Date	Title
NO127814B (fr)	1973-08-20
US4175183A (en)	1979-11-20	Hydroxyalkylated cross-linked regenerated cellulose and method of preparation thereof
US3208994A (en)	1965-09-28	Process for preparing hydrophilic copolymerization and product obtained thereby
EP0047064B1 (fr)	1985-10-02	Procédé pour la préparation de particules poreuses sphériques à base de cellulose
NO170961B (no)	1992-09-28	Kjemikaliebeholder og tilfoerselsanordning for fastgjoeringav denne
US4872987A (en)	1989-10-10	Process for separating and producing chlorogenic acid
JPS6317904A (ja)	1988-01-25	多孔質架橋ポリビニルアルコ−ル粒子の製造法
US4547572A (en)	1985-10-15	Cyclodextrin polymers swelling quickly and to a great extent in water and process for the preparation thereof
JPS6117851B2 (fr)	1986-05-09
US5075432A (en)	1991-12-24	Spherical cyclodextrin polymer beads
JPH0320706B2 (fr)	1991-03-20
Lynch et al.	1956	The adsorption of carbohydrates and related compounds on clay minerals
CN105504295A (zh)	2016-04-20	一种淀粉固载β-环糊精吸附剂的制备方法
CA2577822C (fr)	2012-11-20	Procede de preparation d'une matrice de chromatographie
US4174440A (en)	1979-11-13	Ionic pullulan gels and production thereof
JPH0556761B2 (fr)	1993-08-20
US3634394A (en)	1972-01-11	Method for the preparation of novel ion exchangers on the basis of cellulose
JPH07216002A (ja)	1995-08-15	シクロデキストリン誘導体の製法及びシクロデキストリン誘導体
US3065222A (en)	1962-11-20	Cation exchange starches which retain their original granular form and process for making same
JPS60248729A (ja)	1985-12-09	アミノアルキルアミノ基を有するポリシクロデキストリン系樹脂とその製造方法
GB1001364A (en)	1965-08-18	Process of manufacturing epoxide resins
JPS6011961B2 (ja)	1985-03-29	ポリシクロデキストリンビ−ズの製法
JPH04106101A (ja)	1992-04-08	シクロデキストリンポリマーおよびその製造方法
JPH0196195A (ja)	1989-04-14	生体蛋白質の分離方法
JPS6312099B2 (fr)	1988-03-17