NO172284C - Fremgangsmaate ved fremstilling av et fluoksetin-hydroklorid - Google Patents

Fremgangsmaate ved fremstilling av et fluoksetin-hydroklorid

Info

Publication number: NO172284C
Authority: NO; Norway
Prior art keywords: chem; formula; phenyl; fluoxetine hydrochloride; fluoxetine
Prior art date: 1989-03-03

Application number

NO901013A

Other languages

English (en)

Norwegian (no)

Other versions

NO901013D0 (no

NO901013L (no

NO172284B (no

Inventor

Pekka Juhani Kairisalo

Petri Juhani Hukka

Anitta Hannele Jaervinen

Original Assignee

Orion Corp Fermion

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-03-03

Filing date

1990-03-02

Publication date

1993-06-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8527991&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO172284(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1990-03-02 Application filed by Orion Corp Fermion filed Critical Orion Corp Fermion

1990-03-02 Publication of NO901013D0 publication Critical patent/NO901013D0/no

1990-09-04 Publication of NO901013L publication Critical patent/NO901013L/no

1993-03-22 Publication of NO172284B publication Critical patent/NO172284B/no

1993-06-30 Publication of NO172284C publication Critical patent/NO172284C/no

Links

GIYXAJPCNFJEHY-UHFFFAOYSA-N N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-1-propanamine hydrochloride (1:1) Chemical compound Cl.C=1C=CC=CC=1C(CCNC)OC1=CC=C(C(F)(F)F)C=C1 GIYXAJPCNFJEHY-UHFFFAOYSA-N 0.000 title abstract 3
229960000389 fluoxetine hydrochloride Drugs 0.000 title abstract 3
238000000034 method Methods 0.000 title abstract 3
RTHCYVBBDHJXIQ-UHFFFAOYSA-N N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine Chemical compound C=1C=CC=CC=1C(CCNC)OC1=CC=C(C(F)(F)F)C=C1 RTHCYVBBDHJXIQ-UHFFFAOYSA-N 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
RTHCYVBBDHJXIQ-MRXNPFEDSA-N (R)-fluoxetine Chemical compound O([C@H](CCNC)C=1C=CC=CC=1)C1=CC=C(C(F)(F)F)C=C1 RTHCYVBBDHJXIQ-MRXNPFEDSA-N 0.000 abstract 1
XXSDCGNHLFVSET-UHFFFAOYSA-N 3-(methylamino)-1-phenylpropan-1-ol Chemical compound CNCCC(O)C1=CC=CC=C1 XXSDCGNHLFVSET-UHFFFAOYSA-N 0.000 abstract 1
LNCWFHRJTAQGBG-UHFFFAOYSA-N 3-[benzyl(methyl)amino]-1-phenylpropan-1-one Chemical compound C=1C=CC=CC=1CN(C)CCC(=O)C1=CC=CC=C1 LNCWFHRJTAQGBG-UHFFFAOYSA-N 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229960002464 fluoxetine Drugs 0.000 abstract 1
QULYNCCPRWKEMF-UHFFFAOYSA-N parachlorobenzotrifluoride Chemical compound FC(F)(F)C1=CC=C(Cl)C=C1 QULYNCCPRWKEMF-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/48—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/06—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton from hydroxy amines by reactions involving the etherification or esterification of hydroxy groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Catalysts (AREA)
Jib Cranes (AREA)
Indexing, Searching, Synchronizing, And The Amount Of Synchronization Travel Of Record Carriers (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)

NO901013A 1989-03-03 1990-03-02 Fremgangsmaate ved fremstilling av et fluoksetin-hydroklorid NO172284C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FI891015A FI81083C (fi)	1989-03-03	1989-03-03	Ett foerbaettrat foerfarande foer framstaellning av n-metyl-3-(p-trifluormetylfenoxi)-3-fenylpropylamin hydroklorid.

Publications (4)

Publication Number	Publication Date
NO901013D0 NO901013D0 (no)	1990-03-02
NO901013L NO901013L (no)	1990-09-04
NO172284B NO172284B (no)	1993-03-22
NO172284C true NO172284C (no)	1993-06-30

Family

ID=8527991

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO901013A NO172284C (no)	1989-03-03	1990-03-02	Fremgangsmaate ved fremstilling av et fluoksetin-hydroklorid

Country Status (24)

Country	Link
EP (1)	EP0391070B1 (cs)
JP (1)	JPH0791244B2 (cs)
AT (1)	ATE100440T1 (cs)
AU (1)	AU620497B2 (cs)
BG (1)	BG51156A3 (cs)
CA (1)	CA2010410C (cs)
CS (1)	CS276782B6 (cs)
DD (1)	DD297806A5 (cs)
DE (1)	DE69006072T2 (cs)
DK (2)	DK172360B1 (cs)
ES (1)	ES2062131T3 (cs)
FI (1)	FI81083C (cs)
HR (1)	HRP921278B1 (cs)
HU (1)	HU204769B (cs)
IE (1)	IE63650B1 (cs)
IL (1)	IL92802A (cs)
NO (1)	NO172284C (cs)
PL (1)	PL163884B1 (cs)
PT (1)	PT93302A (cs)
RO (1)	RO105802B1 (cs)
RU (1)	RU1779244C (cs)
SI (1)	SI9010015B (cs)
YU (1)	YU48249B (cs)
ZA (1)	ZA90739B (cs)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL99316A (en)	1991-08-27	1995-03-15	Teva Pharma	Production of fluoxetine and new intermediates
HU9202128D0 (en) *	1992-06-26	1992-10-28	Richter Gedeon Vegyeszet	Method for producing n-methyl-(3-phenyl-3-(4-[trifluoro-methyl])-phenooxi-)-amine
US5618968A (en) *	1993-02-05	1997-04-08	Pliva Farmaceutska Kemijska, Prehrambena I Kozmeticka Industrija, Dionicko Drustvo	N-substituted derivatives of N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine and the procedure for their preparation
US5362886A (en) *	1993-10-12	1994-11-08	Eli Lilly And Company	Asymmetric synthesis
ES2101650B1 (es) *	1995-06-29	1998-01-16	Lilly Sa	Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfenoxi) propilamina.
ES2101654B1 (es) *	1995-07-24	1998-01-16	Lilly Sa	Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfe noxi) propilamina.
ES2101655B1 (es) *	1995-07-28	1998-01-16	Lilly Sa	Procedimiento de preparacion de n-metil-3-fenil-3-(p-trifluorometilfe noxi) propilamina.
ES2103680B1 (es) *	1995-08-03	1998-04-01	Lilly Sa	Procedimiento de preparacion de n-metil-3-fenil-3- (p-trifluorometilfenoxi)propilamina.
ES2103681B1 (es) *	1995-09-19	1998-04-01	Lilly Sa	Procedimiento de preparacion de n-metil-3-fenil - (p-trifluorometilfenoxi) propilamina.
ES2120368B1 (es) *	1996-06-14	1999-07-01	Almirall Prodesfarma Sa	Procedimiento de obtencion de n-metil-3-(p-trifluorometilfenoxi)-3-fenilpropilamina y sus sales farmaceuticamente aceptables.
TW514634B (en) *	1997-10-14	2002-12-21	Lilly Co Eli	Process to make chiral compounds
US6008412A (en) *	1997-10-14	1999-12-28	Eli Lilly And Company	Process to make chiral compounds
US6025517A (en) *	1998-08-03	2000-02-15	Sepracor Inc.	Fluoxetine process from benzoylacetonitrile
JP2002541235A (ja) *	1999-04-09	2002-12-03	イーライ・リリー・アンド・カンパニー	３−アリールオキシ−３−アリールプロピルアミン及びその中間体の製造方法
US6316672B1 (en)	2001-01-31	2001-11-13	Grayson Walker Stowell	Form a of fluoxetine hydrochloride
US6313350B1 (en)	2001-01-31	2001-11-06	Grayson Walker Stowell	Form a of fluoxetine hydrochloride
US6310251B1 (en)	2001-01-31	2001-10-30	Grayson Walker Stowell	Form a of fluoxetine hydrochloride
US6258853B1 (en)	2001-01-31	2001-07-10	Grayson Walker Stowell	Form a of fluoxetine hydrochloride
US6310250B1 (en)	2001-01-31	2001-10-30	Grayson Walker Stowell	Form A of fluoxetine hydrochloride
JP4769464B2 (ja) *	2005-01-12	2011-09-07	広栄化学工業株式会社	アルコール化合物の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4314081A (en) *	1974-01-10	1982-02-02	Eli Lilly And Company	Arloxyphenylpropylamines
GB2060618A (en) *	1979-09-14	1981-05-07	Wyeth John & Brother Ltd	3-Aryl-3-Aryloxypropylamines
JPS6172736A (ja) *	1984-09-18	1986-04-14	Toyo Soda Mfg Co Ltd	エフエドリン誘導体およびその製造方法
GB8500482D0 (en) *	1985-01-09	1985-02-13	Shell Int Research	Substituted phenyl ethers

1989
- 1989-03-03 FI FI891015A patent/FI81083C/fi not_active IP Right Cessation
- 1989-12-19 IL IL9280289A patent/IL92802A/en unknown
- 1989-12-20 IE IE411889A patent/IE63650B1/en not_active IP Right Cessation
1990
- 1990-01-04 SI SI9010015A patent/SI9010015B/sl unknown
- 1990-01-04 YU YU1590A patent/YU48249B/sh unknown
- 1990-01-31 ZA ZA90739A patent/ZA90739B/xx unknown
- 1990-02-20 CA CA002010410A patent/CA2010410C/en not_active Expired - Fee Related
- 1990-02-20 AU AU49969/90A patent/AU620497B2/en not_active Ceased
- 1990-02-20 BG BG091247A patent/BG51156A3/bg unknown
- 1990-02-26 DK DK049790A patent/DK172360B1/da not_active IP Right Cessation
- 1990-02-26 DD DD90338155A patent/DD297806A5/de unknown
- 1990-03-01 ES ES90104018T patent/ES2062131T3/es not_active Expired - Lifetime
- 1990-03-01 DE DE69006072T patent/DE69006072T2/de not_active Revoked
- 1990-03-01 DK DK90104018.8T patent/DK0391070T3/da active
- 1990-03-01 AT AT90104018T patent/ATE100440T1/de not_active IP Right Cessation
- 1990-03-01 PT PT93302A patent/PT93302A/pt not_active Application Discontinuation
- 1990-03-01 EP EP90104018A patent/EP0391070B1/en not_active Revoked
- 1990-03-01 CS CS901003A patent/CS276782B6/cs not_active IP Right Cessation
- 1990-03-02 JP JP2052564A patent/JPH0791244B2/ja not_active Expired - Fee Related
- 1990-03-02 NO NO901013A patent/NO172284C/no not_active IP Right Cessation
- 1990-03-02 RU SU904743358A patent/RU1779244C/ru active
- 1990-03-02 PL PL90284147A patent/PL163884B1/pl unknown
- 1990-03-02 RO RO144334A patent/RO105802B1/ro unknown
- 1990-03-02 HU HU901276A patent/HU204769B/hu not_active IP Right Cessation
1992
- 1992-11-16 HR HRP-15/90A patent/HRP921278B1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
DD297806A5 (de)	1992-01-23
CA2010410C (en)	1997-03-18
DK172360B1 (da)	1998-04-14
RO105802B1 (ro)	1992-12-30
AU620497B2 (en)	1992-02-20
YU1590A (en)	1991-10-31
IE63650B1 (en)	1995-05-31
FI81083C (fi)	1990-09-10
HRP921278A2 (en)	1995-08-31
HU204769B (en)	1992-02-28
FI81083B (fi)	1990-05-31
PT93302A (pt)	1990-11-07
ZA90739B (en)	1990-11-28
SI9010015A (sl)	1998-06-30
ATE100440T1 (de)	1994-02-15
NO901013D0 (no)	1990-03-02
EP0391070B1 (en)	1994-01-19
NO901013L (no)	1990-09-04
ES2062131T3 (es)	1994-12-16
BG51156A3 (bg)	1993-02-15
EP0391070A1 (en)	1990-10-10
CS9001003A2 (en)	1991-09-15
HUT54619A (en)	1991-03-28
NO172284B (no)	1993-03-22
DE69006072T2 (de)	1994-06-30
AU4996990A (en)	1990-09-06
JPH02282352A (ja)	1990-11-19
HU901276D0 (en)	1990-05-28
YU48249B (sh)	1997-09-30
FI891015A0 (fi)	1989-03-03
IE894118L (en)	1990-09-03
RU1779244C (ru)	1992-11-30
IL92802A (en)	1994-01-25
DK49790A (da)	1990-09-04
HRP921278B1 (en)	2000-04-30
PL163884B1 (pl)	1994-05-31
DK0391070T3 (da)	1994-02-28
CA2010410A1 (en)	1990-09-03
DE69006072D1 (de)	1994-03-03
SI9010015B (sl)	1999-06-30
JPH0791244B2 (ja)	1995-10-04
DK49790D0 (da)	1990-02-26
CS276782B6 (en)	1992-08-12

Legal Events

Date	Code	Title	Description
2003-10-27	MM1K	Lapsed by not paying the annual fees	Free format text: LAPSED IN SEPTEMBER 2003

Publication	Publication Date	Title
NO172284C (no)	1993-06-30	Fremgangsmaate ved fremstilling av et fluoksetin-hydroklorid
HUT47217A (en)	1989-02-28	Process for producing pharmaceutical compositions containing indol derivatives as active components
US6417206B1 (en)	2002-07-09	Antitussive/antihist aminic/decongestant compositions
ES499870A0 (es)	1982-06-01	Un procedimiento para la preparacion de derivados de indano
MX11031A (es)	1993-11-01	Proceso para la preparacion de nuevas 1-fenil-3-naftaleniloxipropanaminas producto obtenido y composicion farmaceutica que lo incluye.
KR910007881A (ko)	1991-05-30	아미노피리디닐아미노페놀 및 관련화합물, 이들의 제조방법 및 중간체 및 약제로서의 이들의 용도
ES8308833A1 (es)	1983-10-01	"un metodo para la preparacion de 3-fenil-1-indanaminas".
KR880002825A (ko)	1988-05-11	치환된 인돌리논 유도체를 제조하는 방법
ES8403110A1 (es)	1984-03-01	Un procedimiento para la preparacion de pirbuterol.
FI67364B (fi)	1984-11-30	Foerfarande foer framstaellning av en ny farmakologiskt aktiv 1-fenyl-2-(fenoxi-isopropylamino)-1,3-propandiol
KR830009070A (ko)	1983-12-17	몰포린의 제조방법
KR910000648A (ko)	1991-01-29	페녹시피리딘아민 및 이의 유도체, 제조방법 및 약제로서의 용도
KR910000135A (ko)	1991-01-29	심장혈관활성을 가진 2-아미노-1,2,3,4-테트라히드로나프탈렌 유도체, 그 제조방법 및 이를 함유한 약제 조성물
GR3001493T3 (en)	1992-10-08	D-nor-7-ergoline derivatives, process for preparing them, pharmaceutical composition and use
KR930021617A (ko)	1993-11-22	신규의 아릴피페리딘 유도체, 그의 제조방법 및 이를 함유하는 제약 조성물
Sharman	1973	Catecholamine metabolites in cerebro-spinal fluid
GB1237158A (en)	1971-06-30	Pharmaceutical compositions containing and process for preparing a benzodiopane derivative
ES2013411A6 (es)	1990-05-01	Procedimientos de preparacion de nuevos derivados de la 1-difenilmetilpiperidina.
PY0101652A (es)	2001-12-03	Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors
FR2759091A1 (fr)	1998-08-07	Procede biologique d'obtention de nouveaux derives de l'adenosine et les compositions pharmaceutiques qui les contiennent
NO144605B (no)	1981-06-22	Analogifremgangsmaate for fremstilling av terapeutisk aktive propanol-derivater
TH25186A (th)	1997-05-23	ขบวนการเตรียมไธอีเทนอามีน