NO178193C - Analogifremgangsmåte for fremstilling av terapeutisk aktive 1-heteroaryloksindol-3-karboksamider - Google Patents
Analogifremgangsmåte for fremstilling av terapeutisk aktive 1-heteroaryloksindol-3-karboksamiderInfo
- Publication number
- NO178193C NO178193C NO912696A NO912696A NO178193C NO 178193 C NO178193 C NO 178193C NO 912696 A NO912696 A NO 912696A NO 912696 A NO912696 A NO 912696A NO 178193 C NO178193 C NO 178193C
- Authority
- NO
- Norway
- Prior art keywords
- furyl
- thienyl
- alkyl
- heteroaryloxindole
- carboxamides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1989/000080 WO1990008146A1 (en) | 1989-01-10 | 1989-01-10 | Anti-inflammatory 1-heteroaryl-oxindole-3-carboxamides |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO912696L NO912696L (no) | 1991-07-09 |
| NO912696D0 NO912696D0 (no) | 1991-07-09 |
| NO178193B NO178193B (no) | 1995-10-30 |
| NO178193C true NO178193C (no) | 1996-02-07 |
Family
ID=22214773
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO912696A NO178193C (no) | 1989-01-10 | 1991-07-09 | Analogifremgangsmåte for fremstilling av terapeutisk aktive 1-heteroaryloksindol-3-karboksamider |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5128352A (de) |
| EP (1) | EP0378357B1 (de) |
| JP (1) | JPH0678337B2 (de) |
| KR (1) | KR920006784B1 (de) |
| AT (1) | ATE100096T1 (de) |
| AU (1) | AU616090B2 (de) |
| CA (1) | CA2007651C (de) |
| DE (1) | DE69005833T2 (de) |
| DK (1) | DK0378357T3 (de) |
| ES (1) | ES2062318T3 (de) |
| FI (1) | FI94247C (de) |
| HU (1) | HU217072B (de) |
| IE (1) | IE61796B1 (de) |
| IL (1) | IL92961A0 (de) |
| MY (1) | MY106261A (de) |
| NO (1) | NO178193C (de) |
| NZ (1) | NZ232038A (de) |
| PT (1) | PT92801B (de) |
| WO (1) | WO1990008146A1 (de) |
| ZA (1) | ZA90140B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE301457T1 (de) * | 1995-06-12 | 2005-08-15 | Searle & Co | Mittel, enthaltend einen cyclooxygenase-2 inhibitor und einen 5-lipoxygenase inhibitor |
| JP6903580B2 (ja) | 2014-12-29 | 2021-07-14 | ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ | 乳酸脱水素酵素の小分子阻害剤及びその使用方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3749731A (en) * | 1971-07-08 | 1973-07-31 | Warner Lambert Co | 2-oxo-n-(2-thiazolyl)-3-indoline-carboxamide |
| US4176191A (en) * | 1977-09-06 | 1979-11-27 | Abbott Laboratories | Aminomethylene oxindoles |
| US4476307A (en) * | 1982-09-20 | 1984-10-09 | Pfizer Inc. | Heteroylidene indolone compounds |
| EP0153818B1 (de) * | 1984-02-07 | 1989-03-15 | Pfizer Inc. | 1,3-Disubstituierte 2-Oxindole und deren Anwendung als analgetische und antiinflammatorische Mittel |
| HU203350B (en) * | 1984-08-24 | 1991-07-29 | Pfizer | Process for producing antiinflammatory tricyclic oxindole derivatives |
| US4686224A (en) * | 1984-10-31 | 1987-08-11 | Pfizer Inc. | Oxindole antiinflammatory agents |
| US4644005A (en) * | 1984-10-31 | 1987-02-17 | Pfizer Inc. | Oxindole antiinflammatory agents |
| US4791129A (en) * | 1987-01-20 | 1988-12-13 | Pfizer Inc. | 1,3-dicarboxamidooxindoles as analgesic and antiinflammatory agents |
-
1989
- 1989-01-10 WO PCT/US1989/000080 patent/WO1990008146A1/en not_active Ceased
- 1989-01-10 US US07/721,495 patent/US5128352A/en not_active Expired - Lifetime
- 1989-01-10 HU HU892128A patent/HU217072B/hu not_active IP Right Cessation
-
1990
- 1990-01-03 IL IL92961A patent/IL92961A0/xx not_active IP Right Cessation
- 1990-01-08 MY MYPI90000022A patent/MY106261A/en unknown
- 1990-01-08 NZ NZ232038A patent/NZ232038A/en unknown
- 1990-01-08 PT PT92801A patent/PT92801B/pt not_active IP Right Cessation
- 1990-01-09 IE IE7490A patent/IE61796B1/en not_active IP Right Cessation
- 1990-01-09 AT AT90300228T patent/ATE100096T1/de not_active IP Right Cessation
- 1990-01-09 EP EP90300228A patent/EP0378357B1/de not_active Expired - Lifetime
- 1990-01-09 AU AU47817/90A patent/AU616090B2/en not_active Ceased
- 1990-01-09 DK DK90300228.5T patent/DK0378357T3/da active
- 1990-01-09 ES ES90300228T patent/ES2062318T3/es not_active Expired - Lifetime
- 1990-01-09 ZA ZA90140A patent/ZA90140B/xx unknown
- 1990-01-09 DE DE90300228T patent/DE69005833T2/de not_active Expired - Fee Related
- 1990-01-09 KR KR1019900000166A patent/KR920006784B1/ko not_active Expired
- 1990-01-10 JP JP2003287A patent/JPH0678337B2/ja not_active Expired - Fee Related
- 1990-01-12 CA CA002007651A patent/CA2007651C/en not_active Expired - Fee Related
-
1991
- 1991-07-09 NO NO912696A patent/NO178193C/no not_active IP Right Cessation
- 1991-07-09 FI FI913325A patent/FI94247C/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0378357B1 (de) | 1994-01-12 |
| NO912696L (no) | 1991-07-09 |
| EP0378357A1 (de) | 1990-07-18 |
| DE69005833D1 (de) | 1994-02-24 |
| PT92801A (pt) | 1990-07-31 |
| AU616090B2 (en) | 1991-10-17 |
| PT92801B (pt) | 1995-12-29 |
| DE69005833T2 (de) | 1994-04-28 |
| ZA90140B (en) | 1991-08-28 |
| WO1990008146A1 (en) | 1990-07-26 |
| IL92961A0 (en) | 1990-09-17 |
| AU4781790A (en) | 1990-07-19 |
| NZ232038A (en) | 1991-06-25 |
| DK0378357T3 (da) | 1994-02-14 |
| HUT58084A (en) | 1992-01-28 |
| NO912696D0 (no) | 1991-07-09 |
| ATE100096T1 (de) | 1994-01-15 |
| KR920006784B1 (ko) | 1992-08-17 |
| CA2007651C (en) | 1997-08-19 |
| ES2062318T3 (es) | 1994-12-16 |
| NO178193B (no) | 1995-10-30 |
| IE900074L (en) | 1990-07-10 |
| IE61796B1 (en) | 1994-11-30 |
| FI94247B (fi) | 1995-04-28 |
| CA2007651A1 (en) | 1991-07-12 |
| KR900011763A (ko) | 1990-08-02 |
| JPH0678337B2 (ja) | 1994-10-05 |
| HU217072B (hu) | 1999-11-29 |
| JPH02247174A (ja) | 1990-10-02 |
| MY106261A (en) | 1995-04-29 |
| US5128352A (en) | 1992-07-07 |
| FI94247C (fi) | 1995-08-10 |
| FI913325A0 (fi) | 1991-07-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |