NO180197C - Analogifremgangsmåte for fremstilling av terapeutisk aktive 4-amino-<Delta>4'6-steroider - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive 4-amino-<Delta>4'6-steroider

Info

Publication number: NO180197C
Authority: NO; Norway
Prior art keywords: steroids; amino; depart; preparation; therapeutically active
Prior art date: 1990-08-01

Application number

NO912982A

Other languages

English (en)

Norwegian (no)

Other versions

NO180197B (no

NO912982L (no

NO912982D0 (no

Inventor

Philip Marvin Weintraub

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-01

Filing date

1991-07-31

Publication date

1997-03-05

1991-03-19 Priority claimed from US07/671,555 external-priority patent/US5143909A/en

1991-07-02 Priority claimed from US07/720,899 external-priority patent/US5130424A/en

1991-07-31 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1991-07-31 Publication of NO912982D0 publication Critical patent/NO912982D0/no

1992-02-03 Publication of NO912982L publication Critical patent/NO912982L/no

1996-11-25 Publication of NO180197B publication Critical patent/NO180197B/no

1997-03-05 Publication of NO180197C publication Critical patent/NO180197C/no

Links

150000003431 steroids Chemical class 0.000 title abstract 2
PXIPVTKHYLBLMZ-UHFFFAOYSA-N Sodium azide Chemical compound [Na+].[N-]=[N+]=[N-] PXIPVTKHYLBLMZ-UHFFFAOYSA-N 0.000 abstract 2
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 2
108010066551 Cholestenone 5 alpha-Reductase Proteins 0.000 abstract 1
239000004593 Epoxy Substances 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000012442 inert solvent Substances 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0011—Unsubstituted amino radicals

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Dermatology (AREA)
Diabetes (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cosmetics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

NO912982A 1990-08-01 1991-07-31 Analogifremgangsmåte for fremstilling av terapeutisk aktive 4-amino-<Delta>4'6-steroider NO180197C (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US56141090A	1990-08-01	1990-08-01
US07/671,555 US5143909A (en)	1991-03-19	1991-03-19	Aminosteroids in a method for inhibiting c17-20 lyase
US07/720,899 US5130424A (en)	1990-08-01	1991-07-02	4-amino-delta-4,6-steroids and their use as 5 alpha-reductase inhibitors

Publications (4)

Publication Number	Publication Date
NO912982D0 NO912982D0 (no)	1991-07-31
NO912982L NO912982L (no)	1992-02-03
NO180197B NO180197B (no)	1996-11-25
NO180197C true NO180197C (no)	1997-03-05

Family

ID=27415853

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO912982A NO180197C (no)	1990-08-01	1991-07-31	Analogifremgangsmåte for fremstilling av terapeutisk aktive 4-amino-<Delta>4'6-steroider

Country Status (17)

Country	Link
EP (1)	EP0469547B1 (de)
JP (1)	JP3021818B2 (de)
CN (1)	CN1031574C (de)
AT (1)	ATE138073T1 (de)
AU (1)	AU642757B2 (de)
CA (1)	CA2048243C (de)
DE (1)	DE69119502T2 (de)
DK (1)	DK0469547T3 (de)
ES (1)	ES2089063T3 (de)
FI (1)	FI102378B (de)
GR (1)	GR3020268T3 (de)
HU (1)	HU210042B (de)
IE (1)	IE75199B1 (de)
IL (1)	IL98998A (de)
NO (1)	NO180197C (de)
NZ (1)	NZ239141A (de)
PT (1)	PT98519B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5543406A (en) *	1991-12-20	1996-08-06	Glaxo Wellcome, Inc.	Inhibitors of 5-α-testosterone reductase
US5302589A (en) *	1992-08-07	1994-04-12	Glaxo, Inc.	Heterocyclic inhibitors of 5-α-testosterone reductase
US5486511A (en) *	1993-05-25	1996-01-23	Merrell Dow Pharmaceuticals Inc.	4-amino-17β-(cyclopropyloxy)androst-4-en-3-one, 4-amino-17β-(cyclopropylamino)androst-4-en-3-one and related compounds as C17-20 lyase and 5α-reductase
TW369521B (en) *	1993-09-17	1999-09-11	Smithkline Beecham Corp	Androstenone derivative
US5356935A (en) *	1993-12-13	1994-10-18	Eli Lilly And Company	Reduced phenanthrenes
AU686793B2 (en) *	1994-05-02	1998-02-12	Merrell Pharmaceuticals Inc.	Process for the preparation of 4-amino- 4-3-ketosteroids via 4-nitro-delta 4-3-ketosteroids
US5541322A (en) *	1994-10-14	1996-07-30	Glaxo Wellcome Inc.	Synthesis of 6-azaandrostenones
WO2001005364A1 (en) *	1999-07-15	2001-01-25	The Procter & Gamble Company	Nitrogen-containing steroid compounds and their use to regulate hair growth
JP6353939B1 (ja) *	2017-02-15	2018-07-04	横関油脂工業株式会社	油状組成物、その製法、油性基剤および皮膚外用剤

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1154008A (en) *	1979-05-02	1983-09-20	Thomas R. Blohm	STEROID 5.alpha.-REDUCTASE INHIBITORS
GB8503940D0 (en) *	1985-02-15	1985-03-20	Erba Farmitalia	4-substituted androstendione derivatives

1991
- 1991-07-26 NZ NZ239141A patent/NZ239141A/en unknown
- 1991-07-26 AU AU81356/91A patent/AU642757B2/en not_active Ceased
- 1991-07-29 IL IL9899891A patent/IL98998A/en active IP Right Grant
- 1991-07-30 DE DE69119502T patent/DE69119502T2/de not_active Expired - Fee Related
- 1991-07-30 AT AT91112795T patent/ATE138073T1/de not_active IP Right Cessation
- 1991-07-30 ES ES91112795T patent/ES2089063T3/es not_active Expired - Lifetime
- 1991-07-30 EP EP91112795A patent/EP0469547B1/de not_active Expired - Lifetime
- 1991-07-30 DK DK91112795.9T patent/DK0469547T3/da active
- 1991-07-31 FI FI913658A patent/FI102378B/fi active
- 1991-07-31 CA CA002048243A patent/CA2048243C/en not_active Expired - Fee Related
- 1991-07-31 IE IE270691A patent/IE75199B1/en not_active IP Right Cessation
- 1991-07-31 HU HU912559A patent/HU210042B/hu not_active IP Right Cessation
- 1991-07-31 PT PT98519A patent/PT98519B/pt not_active IP Right Cessation
- 1991-07-31 NO NO912982A patent/NO180197C/no not_active IP Right Cessation
- 1991-08-01 JP JP3214162A patent/JP3021818B2/ja not_active Expired - Lifetime
- 1991-08-01 CN CN91105278A patent/CN1031574C/zh not_active Expired - Fee Related
1996
- 1996-06-19 GR GR960401647T patent/GR3020268T3/el unknown

Also Published As

Publication number	Publication date
EP0469547A2 (de)	1992-02-05
FI102378B1 (fi)	1998-11-30
NZ239141A (en)	1994-04-27
HUT59157A (en)	1992-04-28
FI913658A0 (fi)	1991-07-31
DE69119502D1 (de)	1996-06-20
IE912706A1 (en)	1992-02-12
FI913658L (fi)	1992-02-02
JPH05320189A (ja)	1993-12-03
AU642757B2 (en)	1993-10-28
PT98519B (pt)	1999-01-29
NO180197B (no)	1996-11-25
EP0469547A3 (en)	1992-06-03
AU8135691A (en)	1992-02-06
CA2048243C (en)	2003-04-08
CA2048243A1 (en)	1992-02-02
JP3021818B2 (ja)	2000-03-15
IL98998A (en)	1996-01-19
FI102378B (fi)	1998-11-30
HU912559D0 (en)	1992-01-28
NO912982L (no)	1992-02-03
ES2089063T3 (es)	1996-10-01
CN1031574C (zh)	1996-04-17
IE75199B1 (en)	1997-08-27
NO912982D0 (no)	1991-07-31
CN1059150A (zh)	1992-03-04
PT98519A (pt)	1992-06-30
GR3020268T3 (en)	1996-09-30
DE69119502T2 (de)	1996-09-26
DK0469547T3 (da)	1996-06-10
EP0469547B1 (de)	1996-05-15
ATE138073T1 (de)	1996-06-15
IL98998A0 (en)	1992-07-15
HU210042B (en)	1995-01-30

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Legal Events

Date	Code	Title	Description
2001-03-05	MM1K	Lapsed by not paying the annual fees	Free format text: LAPSED IN JANUARY 2001