NO20003784L - FremgangsmÕte for fremstilling av enansiomert rene cykloalkanoindolkarboksylsyre og azaindolkarboksylsyrer og pyrimido 1,2a indolkarboksylsyrer og derivater derav - Google Patents

FremgangsmÕte for fremstilling av enansiomert rene cykloalkanoindolkarboksylsyre og azaindolkarboksylsyrer og pyrimido 1,2a indolkarboksylsyrer og derivater derav

Info

Publication number
NO20003784L
NO20003784L NO20003784A NO20003784A NO20003784L NO 20003784 L NO20003784 L NO 20003784L NO 20003784 A NO20003784 A NO 20003784A NO 20003784 A NO20003784 A NO 20003784A NO 20003784 L NO20003784 L NO 20003784L
Authority
NO
Norway
Prior art keywords
acids
pyrimido
preparation
pure
derivatives
Prior art date
Application number
NO20003784A
Other languages
English (en)
Other versions
NO20003784D0 (no
Inventor
Jan-Bernd Lenfers
Peter Fey
Paul Naab
Kai Van Laak
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO20003784L publication Critical patent/NO20003784L/no
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NO20003784D0 publication Critical patent/NO20003784D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
    • C07C69/616—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62—Halogen-containing esters
    • C07C69/65—Halogen-containing esters of unsaturated acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Fremgangsmåte for fremstilling av enantiomert rene cykloalkanoindolkarboksylsyre og enantiomer-rene cykloalkanoindol- og azaindol- og pyrimido[l,2a]mdo[karboksylsyrer og deres aktiverte derivater med den generelle formel (I) CO-Q der A, Q og T er som angitt i beskrivelsen.
NO20003784A 1996-04-04 2000-07-24 FremgangsmÕte for fremstilling av enansiomert rene cykloalkanoindolkarboksylsyre og azaindolkarboksylsyrer og pyrimido 1,2a indolkarboksylsyrer og derivater derav NO20003784D0 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19613549A DE19613549A1 (de) 1996-04-04 1996-04-04 Verfahren zur Herstellung von enantiomerenreinen Cycloalkano-indol- und azaindol-carbonsäuren und deren aktivierte Derivate

Publications (2)

Publication Number Publication Date
NO20003784L true NO20003784L (no) 1997-10-06
NO20003784D0 NO20003784D0 (no) 2000-07-24

Family

ID=7790501

Family Applications (2)

Application Number Title Priority Date Filing Date
NO971513A NO308301B1 (no) 1996-04-04 1997-04-03 FremgangsmÕte for fremstilling av enantiomer-rene cykloalkanoindol- og azaindol- og pyrimido[1,2a]- indolkarboksylsyrer og deres aktiverte derivater, mellomprodukter samt anvendelse av disse
NO20003784A NO20003784D0 (no) 1996-04-04 2000-07-24 FremgangsmÕte for fremstilling av enansiomert rene cykloalkanoindolkarboksylsyre og azaindolkarboksylsyrer og pyrimido 1,2a indolkarboksylsyrer og derivater derav

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO971513A NO308301B1 (no) 1996-04-04 1997-04-03 FremgangsmÕte for fremstilling av enantiomer-rene cykloalkanoindol- og azaindol- og pyrimido[1,2a]- indolkarboksylsyrer og deres aktiverte derivater, mellomprodukter samt anvendelse av disse

Country Status (27)

Country Link
US (1) US5952498A (no)
EP (1) EP0799829B1 (no)
JP (2) JP4235268B2 (no)
KR (1) KR970069988A (no)
CN (2) CN1067394C (no)
AR (2) AR006544A1 (no)
AT (1) ATE246193T1 (no)
AU (1) AU722592B2 (no)
BR (1) BR9701672A (no)
CA (1) CA2201435C (no)
CZ (1) CZ102197A3 (no)
DE (2) DE19613549A1 (no)
DZ (1) DZ2202A1 (no)
EE (1) EE9700079A (no)
ES (1) ES2202506T3 (no)
HR (1) HRP970178A2 (no)
HU (1) HU218494B (no)
ID (1) ID16794A (no)
IL (1) IL120591A (no)
MA (1) MA24130A1 (no)
NO (2) NO308301B1 (no)
NZ (1) NZ314498A (no)
PL (1) PL319269A1 (no)
SG (1) SG60050A1 (no)
SK (1) SK42897A3 (no)
TN (1) TNSN97060A1 (no)
ZA (1) ZA972831B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4435477A1 (de) * 1994-10-04 1996-04-11 Bayer Ag Cycloalkano-indol- und -azaindol-derivate
AU2001244635A1 (en) * 2000-03-30 2001-10-15 Yamanouchi Pharmaceutical Co..Ltd. Hydrazide derivatives
WO2005051382A1 (ja) * 2003-11-28 2005-06-09 Astellas Pharma Inc. 脂質低下作用増強剤
PT1725234E (pt) 2004-03-05 2013-03-04 Univ Pennsylvania Métodos com efeitos secundários reduzidos para tratamento de patologias ou doenças associadas a hiperlipidemia e hipercolesterolemia
EP1737460A2 (en) * 2004-04-09 2007-01-03 Janssen Pharmaceutica N.V. Intermittent dosing regimen for the treatment of overweight with mtp-inhibitors
EP1951220A2 (en) * 2005-10-18 2008-08-06 Aegerion Pharmaceuticals Compositions for lowering serum cholesterol and/or triglycerides
JP2009537505A (ja) * 2006-05-18 2009-10-29 バイエル・ヘルスケア・アクチェンゲゼルシャフト インプリタピドを含む薬学的組成物およびこの薬学的組成物の使用方法
JP2010513534A (ja) * 2006-12-21 2010-04-30 エージェリオン ファーマシューティカルズ， インコーポレイテッド Ｍｔｐインヒビターおよびコレステロール吸収インヒビターを含む組み合わせを用いて肥満症を処置する方法
WO2008124384A2 (en) * 2007-04-03 2008-10-16 Aegerion Pharmaceuticals, Inc. Combinations of mtp inhibitors with cholesterol absorption inhibitors or interferon for treating hepatitis c
SI2968284T1 (sl) 2013-03-14 2021-08-31 Osteoqc Inc. Alkil-amin harmin derivati za pospeševanje rasti kosti
JP7695496B2 (ja) 2018-08-14 2025-06-19 オシフィ セラピューティクス リミティド ライアビリティ カンパニー フルオロβ－カルボリン化合物
EP3836923B1 (en) 2018-08-14 2024-10-16 OssiFi Therapeutics LLC Pyrrolo - dipyridine compounds for the treatment of bone loss
BR112023000808A2 (pt) 2020-07-29 2023-02-07 Amryt Pharmaceuticals Inc Lomitapida para uso em métodos para tratar hiperlipidemia e hipercolesterolemia em pacientes pediátricos

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3900261A1 (de) * 1988-05-31 1989-12-07 Bayer Ag Substituierte 4-(chinolin-2-yl-methoxy) phenyl-essigsaeure-derivate
DE4200954A1 (de) * 1991-04-26 1992-10-29 Bayer Ag Heterocyclisch substituierte phenylessigsaeurederivate
DE4208051A1 (de) * 1992-03-13 1993-09-16 Bayer Ag Substituierte phenylessigsaeureamide
DE4302956A1 (de) * 1993-02-03 1994-08-04 Bayer Ag Substituierte Imidazo(4,5-b)pyridine und Benzimidazole
DE4435477A1 (de) * 1994-10-04 1996-04-11 Bayer Ag Cycloalkano-indol- und -azaindol-derivate

Also Published As

Publication number Publication date
AR012048A2 (es) 2000-09-27
JPH1045759A (ja) 1998-02-17
CN1330065A (zh) 2002-01-09
DZ2202A1 (fr) 2002-12-03
EE9700079A (et) 1997-10-15
IL120591A0 (en) 1997-08-14
US5952498A (en) 1999-09-14
CN1184109A (zh) 1998-06-10
HUP9700698A1 (hu) 1998-01-28
NZ314498A (en) 1999-09-29
JP4235268B2 (ja) 2009-03-11
DE19613549A1 (de) 1997-10-09
SG60050A1 (en) 1999-02-22
CN1067394C (zh) 2001-06-20
PL319269A1 (en) 1997-10-13
ES2202506T3 (es) 2004-04-01
NO971513L (no) 1997-10-06
BR9701672A (pt) 1998-11-03
IL120591A (en) 2000-11-21
AU722592B2 (en) 2000-08-10
TNSN97060A1 (fr) 2005-03-15
EP0799829B1 (de) 2003-07-30
MX9702446A (es) 1997-10-31
CA2201435C (en) 2006-12-12
NO20003784D0 (no) 2000-07-24
NO971513D0 (no) 1997-04-03
MA24130A1 (fr) 1997-10-01
KR970069988A (ko) 1997-11-07
EP0799829A1 (de) 1997-10-08
NO308301B1 (no) 2000-08-28
ID16794A (id) 1997-11-13
CZ102197A3 (en) 1997-10-15
JP2008169218A (ja) 2008-07-24
ZA972831B (en) 1997-10-31
DE59710487D1 (de) 2003-09-04
HU9700698D0 (en) 1997-05-28
SK42897A3 (en) 1997-10-08
AR006544A1 (es) 1999-09-08
ATE246193T1 (de) 2003-08-15
HU218494B (hu) 2000-09-28
HRP970178A2 (en) 1998-04-30
AU1660297A (en) 1997-10-09
CA2201435A1 (en) 1997-10-04

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