NO20004362L - S-substituerte 11<beta>-benzaldoksim-østra-4,9-dien- karboksylsyretiolestere, fremgangsmÕte for deres fremstilling, samt farmasøytiske preparater inneholdende disse forbindelser - Google Patents

S-substituerte 11<beta>-benzaldoksim-østra-4,9-dien- karboksylsyretiolestere, fremgangsmÕte for deres fremstilling, samt farmasøytiske preparater inneholdende disse forbindelser

Info

Publication number
NO20004362L
NO20004362L NO20004362A NO20004362A NO20004362L NO 20004362 L NO20004362 L NO 20004362L NO 20004362 A NO20004362 A NO 20004362A NO 20004362 A NO20004362 A NO 20004362A NO 20004362 L NO20004362 L NO 20004362L
Authority
NO
Norway
Prior art keywords
compounds
benzaldoxime
estra
substituted
pharmaceutical preparations
Prior art date
Application number
NO20004362A
Other languages
English (en)
Other versions
NO316977B1 (no
NO20004362D0 (no
Inventor
Gerd Schubert
Sven Ring
Guenther Kaufmann
Walter Elger
Birgit Schneider
Original Assignee
Jenapharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jenapharm Gmbh filed Critical Jenapharm Gmbh
Publication of NO20004362D0 publication Critical patent/NO20004362D0/no
Publication of NO20004362L publication Critical patent/NO20004362L/no
Publication of NO316977B1 publication Critical patent/NO316977B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/46—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/006—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20004362A 1998-03-03 2000-09-01 S-substituerte 11<beta>-benzaldoksim-ostra-4,9-dien-karboksylsyretiolestere, fremgangsmate for deres fremstilling, farmasoytiske preparater inneholdende disse forbindelser, samt anvendelse av forbindelsene til fremstilling av medikamenter og prevensjonsmi NO316977B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19809845A DE19809845A1 (de) 1998-03-03 1998-03-03 S-substituierte 11beta-Benzaldoxim-estra-4,9-dien-kohlensäurethiolester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
PCT/DE1999/000408 WO1999045023A1 (de) 1998-03-03 1999-02-10 S-SUBSTITUIERTE 11β-BENZALDOXIM-ESTRA-4,9-DIEN-KOHLENSÄURETHIOLESTER, VERFAHREN ZU DEREN HERSTELLUNG UND DIESE VERBINDUNGEN ENTHALTENE PHARMAZEUTISCHE ZUBEREITUNGEN

Publications (3)

Publication Number Publication Date
NO20004362D0 NO20004362D0 (no) 2000-09-01
NO20004362L true NO20004362L (no) 2000-10-31
NO316977B1 NO316977B1 (no) 2004-07-12

Family

ID=7860080

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004362A NO316977B1 (no) 1998-03-03 2000-09-01 S-substituerte 11<beta>-benzaldoksim-ostra-4,9-dien-karboksylsyretiolestere, fremgangsmate for deres fremstilling, farmasoytiske preparater inneholdende disse forbindelser, samt anvendelse av forbindelsene til fremstilling av medikamenter og prevensjonsmi

Country Status (28)

Country Link
US (1) US6365582B1 (no)
EP (1) EP1060187B1 (no)
JP (1) JP3796405B2 (no)
KR (1) KR100488823B1 (no)
CN (1) CN1208341C (no)
AT (1) ATE237627T1 (no)
AU (1) AU749163B2 (no)
BG (1) BG64735B1 (no)
BR (1) BR9908458A (no)
CA (1) CA2322471C (no)
CZ (1) CZ20003125A3 (no)
DE (2) DE19809845A1 (no)
DK (1) DK1060187T3 (no)
EA (1) EA002766B1 (no)
EE (1) EE04242B1 (no)
ES (1) ES2197634T3 (no)
HU (1) HUP0100962A3 (no)
ID (1) ID26972A (no)
IL (1) IL137851A (no)
IS (1) IS5579A (no)
NO (1) NO316977B1 (no)
NZ (1) NZ506048A (no)
PL (1) PL193687B1 (no)
PT (1) PT1060187E (no)
SK (1) SK284177B6 (no)
TR (1) TR200002506T2 (no)
UA (1) UA59437C2 (no)
WO (1) WO1999045023A1 (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19906152B4 (de) 1999-02-10 2005-02-10 Jenapharm Gmbh & Co. Kg Wirkstoffhaltige Laminate für Transdermalsysteme
EE05172B1 (et) * 1999-08-31 2009-06-15 Jenapharm Gmbh & Co. Kg Mesoprogestiinid (progesterooniretseptori modulaatorid) healoomuliste hormoons?ltuvate gnekoloogiliste haiguste raviks ja v„ltimiseks
US8193252B1 (en) 1999-08-31 2012-06-05 Bayer Pharma AG Mesoprogestins (progesterone receptor modulators) for the treatment and prevention of benign hormone dependent gynecological disorders
US7629334B1 (en) * 1999-08-31 2009-12-08 Bayer Schering Pharma Aktiengesellschaft Mesoprogrestins (progesterone receptor modulations) as a component of compositions for hormone replacement therapy (HRT)
EP1605949A2 (en) * 1999-08-31 2005-12-21 Schering Aktiengesellschaft Mesoprogestins (progesterone receptor modulators) as a component of female contraceptives
SI20851B (sl) * 1999-08-31 2009-06-30 Bayer Schering Pharma Ag Mezoprogestini (modulatorji receptorja progesterona) kot komponenta pripravkov za nadomestno zdravljenje s hormoni (NZH)
EP1285927A3 (de) * 2001-08-16 2005-06-29 Schering Aktiengesellschaft Verwendung von Glucocorticoid-Rezeptorantagonisten zur Vorbeugung und Behandlung von Erkrankungen des männlichen Reproduktionssystems
DE10221034A1 (de) * 2002-05-03 2003-11-20 Schering Ag 17alpha-Fluoralkyl-11ß-benzaldoxim-Steroide, Verfahren zu deren Herstellung, diese Steroide enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
WO2004014935A1 (de) * 2002-08-02 2004-02-19 Schering Aktiengesellschaft Progesteronrezeptormodulatoren mit erhöhter antigonadotroper aktivität für die weibliche fertilitätskontrolle und hormonersatztherapie
DE10236405A1 (de) * 2002-08-02 2004-02-19 Schering Ag Progesteronrezeptormodulatoren mit erhöhter antigonadotroper Aktivität für die weibliche Fertilitätskontrolle und Hormonersatztherapie
DE102005059222B4 (de) * 2005-12-08 2007-10-11 Bayer Schering Pharma Ag 11ß-Benzaldoximderivate von D-Homoestra-4,9-dien-3-onen
ES2814343T3 (es) 2006-10-24 2021-03-26 Allergan Pharmaceuticals Int Ltd Composiciones y métodos para suprimir las proliferaciones endometriales
US7981927B2 (en) 2007-03-07 2011-07-19 Janssen Pharmaceutica N.V. Steroids derivatives as selective progesterone receptor modulators
TWI539953B (zh) 2008-04-28 2016-07-01 瑞波若斯治療學公司 用於治療乳癌之組成物和方法
DE102009034525A1 (de) * 2009-07-21 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
JP5894143B2 (ja) 2010-03-22 2016-03-23 リプロス セラピューティクス インコーポレイテッド 抗黄体ホルモンの無毒送達のための組成物および方法
EP2664325A1 (en) * 2012-05-16 2013-11-20 PregLem S.A. Methods for preventing or treating androgen mediated diseases

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4039677A (en) * 1976-03-01 1977-08-02 Syntex (U.S.A.) Inc. Novel 1-phenethylimidazoles
ZA8231B (en) * 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained
DE3504421A1 (de) * 1985-02-07 1986-08-07 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 11ss-phenyl-gonane, deren herstellung und diese enthaltende pharmazeutische praeparate
DE4332284C2 (de) * 1993-09-20 1997-05-28 Jenapharm Gmbh 11-Benzaldoxim-17beta-methoxy-17alpha-methoxymethyl-estradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE4332283A1 (de) * 1993-09-20 1995-04-13 Jenapharm Gmbh Neue 11-Benzaldoximestradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US5576310A (en) * 1994-09-20 1996-11-19 Jenapharm Gmbh 11-benzaldoxime-17β-methoxy-17α-methoxymethyl-estrasdiene derivatives, methods for their production and pharmaceuticals containing such compounds
EP0787002B1 (de) 1994-10-24 2006-12-13 Schering Aktiengesellschaft Kompetitive progesteronantagonisten zur bedarfsorientierten weiblichen fertilitätskontrolle
ZA9510926B (en) * 1994-12-23 1996-07-03 Schering Ag Compounds with progesterone-antagonistic and antiestrogenic action to be used together for female contraception
UA57703C2 (uk) 1995-03-14 2003-07-15 Шерінг Актієнгезеллшафт Спосіб стимуляції та спосіб інгібування дозрівання шийки матки

Also Published As

Publication number Publication date
HUP0100962A3 (en) 2002-07-29
HUP0100962A2 (hu) 2001-09-28
NZ506048A (en) 2003-05-30
WO1999045023A1 (de) 1999-09-10
DK1060187T3 (da) 2003-08-11
IL137851A0 (en) 2001-10-31
PT1060187E (pt) 2003-09-30
BG104712A (en) 2001-02-28
KR100488823B1 (ko) 2005-05-12
DE59905075D1 (de) 2003-05-22
EE200000500A (et) 2002-02-15
IL137851A (en) 2005-06-19
SK284177B6 (sk) 2004-10-05
CN1291990A (zh) 2001-04-18
BG64735B1 (bg) 2006-01-31
ID26972A (id) 2001-02-22
KR20010041536A (ko) 2001-05-25
PL342449A1 (en) 2001-06-04
AU3406799A (en) 1999-09-20
TR200002506T2 (tr) 2000-12-21
US6365582B1 (en) 2002-04-02
CA2322471C (en) 2007-04-24
EA002766B1 (ru) 2002-08-29
EP1060187A1 (de) 2000-12-20
NO316977B1 (no) 2004-07-12
NO20004362D0 (no) 2000-09-01
EE04242B1 (et) 2004-02-16
ATE237627T1 (de) 2003-05-15
JP3796405B2 (ja) 2006-07-12
JP2002505335A (ja) 2002-02-19
CN1208341C (zh) 2005-06-29
UA59437C2 (uk) 2003-09-15
EA200000896A1 (ru) 2001-04-23
SK13052000A3 (sk) 2001-11-06
AU749163B2 (en) 2002-06-20
BR9908458A (pt) 2000-11-14
EP1060187B1 (de) 2003-04-16
DE19809845A1 (de) 1999-09-09
IS5579A (is) 2000-07-28
ES2197634T3 (es) 2004-01-01
CZ20003125A3 (cs) 2002-01-16
PL193687B1 (pl) 2007-03-30
CA2322471A1 (en) 1999-09-10

Similar Documents

Publication Publication Date Title
NO20004362D0 (no) S-substituerte 11&lt;beta&gt;-benzaldoksim-østra-4,9-dien- karboksylsyretiolestere, fremgangsmÕte for deres fremstilling, samt farmasøytiske preparater inneholdende disse forbindelser
CY1107438T1 (el) Παραγωγα καρβοξυλικου οξεος, τα οποια παρεμποδιζουν την συνδεσιν ιντεγκρινων εις τους υποδοχεις των
HUP9902121A2 (hu) Gonadotropin-leadó hormon antagonista hatású indolszármazékok és ezeket a vegyületeket tartalmazó gyógyszerkészítmények
NO20005431D0 (no) Gelérbare farmasøytiske preparater
DE60137399D1 (de) Propansäurederivate die die Bindung von Integrinen an ihre Rezeptoren hemmen
DK1090029T3 (da) 14,15-Cyclopropansteroider fra 19-norandrostan-rækken, fremgangsmåde til deres fremstilling, og farmaceutiske præparater indeholdende disse forbindelser
BR0010349B1 (pt) derivados de ácido propanóico que inibem a ligação de integrinas aos seus receptores.
EP0244832A2 (de) Ungesättigte Fettsäuren enthaltende Zubereitungen für die Synthese von Prostaglandinen und Hydroxyfettsäuren in biologischen Systemen
UA35607C2 (uk) Похідні оксазолідинонкарбонової кислоти, спосіб їх одержання, фармацевтична композиція і спосіб її одержання
ATE40127T1 (de) 1,5-benzothiazepinderivate, verfahren zu ihrer herstellung und arzneimittel.
DE2963010D1 (en) 3-chloro-6-hydroxy-5-methylbenzoic acid derivatives, corresponding pharmaceutical preparations, growth promoting compositions, the use of the compounds for promoting growth in certain animals and their manufacture
EP0301474A3 (en) New cysteine derivatives having expectorant activity
BR9810031A (pt) Derivados de ácido pirrolidina carboxìlico como antagonistas á endotelina
PT1090028E (pt) 14,15-ciclopropano-androstanos insaturados processo para a sua preparacao e composicoes farmaceuticas que contem estes compostos
PT1157028E (pt) Novos derivados de esteroides 11.beta.-substituidos seus processos de preparacao e intermediarios deste processo sua aplicacao a titulo de medicamentos e composicoes que os contem
UY24851A1 (es) Derivados de ácidos n-acil-alfa-aminados
IT9021967A0 (it) Composizioni farmaceutiche contenenti acido 2-(2-pirrolidon-5-carbonilamido)-3-mercaptopropionico, per il trattamento di malattie connesse auna carenza di glutatione